{"id":24239,"date":"2022-08-18T11:16:43","date_gmt":"2022-08-18T11:16:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24239"},"modified":"2022-08-20T08:12:54","modified_gmt":"2022-08-20T08:12:54","slug":"tadim","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tadim\/","title":{"rendered":"Tadim &#8211; Colistimethate sodium uses, dose and side effects"},"content":{"rendered":"\n<p>1 million international units (IU)&nbsp;Powder for&nbsp;infusion&nbsp;, solution<br>colistimethate sodium<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">WHAT TADIM IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<p>Tadim contains colistimethate sodium.&nbsp;It is an&nbsp;<strong>antibiotic<\/strong>&nbsp;given by&nbsp;injection&nbsp;to treat certain types of serious&nbsp;infections&nbsp;caused by certain bacteria.<\/p>\n\n\n\n<p>Tadim is used when other&nbsp;antibiotics&nbsp;are not suitable.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">WHAT YOU NEED TO KNOW BEFORE YOU RECEIVE TADIM<\/h2>\n\n\n\n<p>In some cases, your doctor may decide not to prescribe Tadim.<\/p>\n\n\n\n<p><strong>Do not use Tadim and consult your doctor if:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are&nbsp;<strong>allergic<\/strong>&nbsp;to colistimethate sodium, colistin, or other polymyxins.<\/li><\/ul>\n\n\n\n<p><strong>If this applies to you, talk to your doctor before receiving Tadim.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with Tadim and consult a doctor, pharmacist or doctor if:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>you have or have had&nbsp;<strong>kidney problems;<\/strong><\/li><li>you suffer from&nbsp;<strong>myasthenia gravis<\/strong>&nbsp;(a rare disease where your muscles are extremely weak and tire very quickly);<\/li><li>you suffer from&nbsp;<strong>porphyria<\/strong>&nbsp;(a rare metabolic disease that some people are born with).<\/li><\/ul>\n\n\n\n<p>In premature and newborn babies, special care should be taken when using Tadim because the kidneys are not fully developed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use of other medicines<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.&nbsp;<strong>These medicines can affect the effect of Tadim.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Medicines that can affect your kidney function.\u00a0If you take Tadim at the same time as these medicines, the risk of kidney damage may increase.<\/li><li>Medicines that can affect the nervous system.\u00a0If you take Tadim at the same time as these medicines, the risk of\u00a0side effects\u00a0in the nervous system may increase.<\/li><li>Medicines called muscle relaxants, are often used during anesthesia.\u00a0Tadim can increase the effect of these medicines.\u00a0If you are going to be anesthetized, you must tell the anesthesiologist that you have Tadim.<\/li><\/ul>\n\n\n\n<p>If you suffer from\u00a0myasthenia gravis\u00a0and also use other\u00a0antibiotics\u00a0called\u00a0macrolides\u00a0(such as azithromycin, clarithromycin, or erythromycin) or\u00a0antibiotics\u00a0called\u00a0fluoroquinolones\u00a0(such as ofloxacin, norfloxacin, and\u00a0ciprofloxacin\u00a0), while taking Tadim increases the risk of muscle weakness and breathing difficulties.<\/p>\n\n\n\n<p>If you receive Tadim as an\u00a0infusion\u00a0at the same time as colistimethate sodium as an\u00a0inhalation, it may increase the risk of\u00a0side effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>You can use Tadim if you are pregnant or trying to become pregnant if your doctor considers that the benefits outweigh the possible risks.&nbsp;It is not known whether using Tadim can harm your unborn baby.<\/p>\n\n\n\n<p>You should not breastfeed while using this medicine, as Tadim can pass into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tadim can make you dizzy, confused, or cause vision problems e.g.\u00a0blurred vision\u00a0If this happens, do not drive, use tools or operate machinery.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO GET TADIM<\/h2>\n\n\n\n<p>Your treatment with Tadim is given by your doctor as&nbsp;an infusion&nbsp;into a vein over 30-60 minutes.<\/p>\n\n\n\n<p>The normal daily\u00a0dose\u00a0for adults is 9 million international units, divided into two or three\u00a0doses.\u00a0If you are quite sick, you will receive a higher\u00a0dose\u00a0of 9 million international units once at the start of treatment.<\/p>\n\n\n\n<p>In some cases, your doctor may decide to give a higher daily&nbsp;dose&nbsp;of up to 12 million international units.<\/p>\n\n\n\n<p>The normal\u00a0dose\u00a0for a child weighing up to 40 kg is 75,000 to 150,000 international units per kilogram of body weight, divided into three\u00a0doses.<\/p>\n\n\n\n<p>Higher\u00a0doses\u00a0have sometimes been given in\u00a0cystic fibrosis.<\/p>\n\n\n\n<p>Children and adults with kidney problems, including people treated with\u00a0dialysis, are normally given a lower\u00a0dose.\u00a0Your doctor will check your kidney function regularly while you are receiving Tadim.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you receive too much Tadim.<\/h2>\n\n\n\n<p>Because a doctor or nurse will give you Tadim, it is unlikely that you will receive an incorrect\u00a0dose.\u00a0Tell your doctor or healthcare professional if you have any questions about the amount of medicine you are given.<\/p>\n\n\n\n<p>Symptoms that you may get if you have received too much Tadim:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness&nbsp;and&nbsp;vertigo<\/li><li>slurred speech<\/li><li>visual disturbances<\/li><li>confusion<\/li><li>mental disorder<\/li><li>flushing&nbsp;(&nbsp;redness&nbsp;of the face)<\/li><li>kidney problems<\/li><li>muscle weakness<\/li><li>feeling like you can&#8217;t breathe<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you have not received Tadim as you should<\/h2>\n\n\n\n<p>Contact a doctor or healthcare professional if you think you have missed a\u00a0dose\u00a0of Tadim and it has been\u00a0<strong>less than 3\u00a0<\/strong><strong>hours<\/strong>\u00a0since you should have received a\u00a0dose.<\/p>\n\n\n\n<p>If it is\u00a0<strong>more than 3 hours<\/strong>\u00a0after the missed\u00a0dose, the doctor or nurse will wait until the next\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop receiving Tadim<\/h2>\n\n\n\n<p>Your doctor will decide how long you should receive Tadim.\u00a0The treatment must be completed according to the doctor&#8217;s instructions, otherwise, the symptoms may worsen.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, Tadim can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Tadim can sometimes cause\u00a0<strong>allergic<\/strong>\u00a0reactions such as\u00a0<strong>skin rash<\/strong>\u00a0or red and raised skin rash, swollen eyelids, face, lips, mouth, or tongue,\u00a0itching, and difficulty breathing or swallowing.\u00a0If this occurs, treatment with\u00a0Tadim must be stopped immediately.<\/p>\n\n\n\n<p>Tadim can also affect your\u00a0<strong>kidneys<\/strong>, especially if the\u00a0dose\u00a0is high or if you are using other medicines that affect the kidneys.<\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(affects more than 1 person in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blood tests can show changes in kidney function<\/li><li>headache<\/li><li>tingling or numbness around the mouth, lips and face<\/li><li>itching<\/li><li>muscle weakness<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(affects less than 1 person in 1,000)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney failure<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;can be<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>difficulty controlling movements<\/li><li>tenderness at the injection site<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO STORE TADIM<\/h2>\n\n\n\n<p>Keep Tadim out of the sight and reach of children.<\/p>\n\n\n\n<p>Use Tadim before the expiry date which is stated on the vial or carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Unopened Tadim bottles do not require special storage instructions.<\/p>\n\n\n\n<p>Tadim contains no\u00a0preservatives.\u00a0After\u00a0preparation, Tadim should be used immediately.<\/p>\n\n\n\n<p>Doctors or healthcare professionals will dispose of unused medicine safely.&nbsp;These measures will help to protect the environment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">OTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The&nbsp;<strong>active substance<\/strong>&nbsp;is colistimethate sodium<\/li><li>Each&nbsp;vial&nbsp;contains 1 million international units (IU) of colistimethate sodium, which weighs approximately 80 mg.&nbsp;There are no other ingredients.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tadim is supplied as a powder in a\u00a0glass\u00a0vial.\u00a0The powder must be prepared into an infusion solution.<\/p>\n\n\n\n<p>Tadim is delivered packaged in boxes of 10 vials.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Zambon S.p.A<\/p>\n\n\n\n<p>Via Lillo del Duca 10<\/p>\n\n\n\n<p>20091 Bresso (MI) &#8211; Italy<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Xellia Pharmaceuticals ApS<\/p>\n\n\n\n<p>Dalslandsgade 11<\/p>\n\n\n\n<p>DK- 2300, Copenhagen S<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Agent<\/strong><\/p>\n\n\n\n<p>Zambon Sweden, Branch of Zambon Nederland BVMedicon Village<\/p>\n\n\n\n<p>223 81 Lund,<\/p>\n\n\n\n<p>Phone: +47 815 300 30<\/p>\n\n\n\n<p>Email: contact@zambongroup.com<\/p>\n\n\n\n<p><strong>This medicine is approved in the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Austria, Netherlands, Sweden: Tadim<\/p>\n\n\n\n<p>Germany, Denmark, Norway, UK: Promixin<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tadim contains colistimethate sodium.\u00a0It is an\u00a0antibiotic\u00a0given by\u00a0injection\u00a0to treat certain types of serious\u00a0infections\u00a0caused by certain bacteria.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[25163,25169,6761,6763,25164,25168,25165,6762,25167,25166],"class_list":["post-24239","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-colistimethate-sodium","tag-benefits-of-tadim","tag-colistimethate-sodium","tag-colistimethate-sodium-side-effects","tag-tadim","tag-tadim-side-effects","tag-what-colistimethate-sodium-is-used-for","tag-what-is-colistimethate-sodium","tag-what-is-tadim","tag-what-tadim-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24239"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24239\/revisions"}],"predecessor-version":[{"id":24283,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24239\/revisions\/24283"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}