{"id":24195,"date":"2022-08-17T10:23:36","date_gmt":"2022-08-17T10:23:36","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24195"},"modified":"2022-08-18T11:06:03","modified_gmt":"2022-08-18T11:06:03","slug":"tadalafil-orion","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tadalafil-orion\/","title":{"rendered":"Tadalafil Orion &#8211; Tadalafil uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg&nbsp;film-coated tablets<br>tadalafil<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tadalafil Orion is and what it is used for<\/h2>\n\n\n\n<p>Tadalafil Orion contains the active substance tadalafil which belongs to a group of medicines called&nbsp;phosphodiesterase&nbsp;type 5 inhibitors.<\/p>\n\n\n\n<p>Tadalafil Orion 5 mg is used for the treatment of adult men with:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Erectile dysfunction<\/strong>.\u00a0This means that a man cannot get, or maintain, a hard and erect penis, sufficient for sexual intercourse.\u00a0Tadalafil has been shown to\u00a0significantly\u00a0improve the ability to have a hard and erect penis, sufficient for sexual intercourse. Tadalafil works during sexual stimulation by relaxing the blood vessels in the penis, so that blood can flow in.\u00a0This results in improved erectile function.\u00a0If you do not have\u00a0erectile dysfunction, Tadalafil will not help.\u00a0It is important to remember that tadalafil has no effect if you are not sexually stimulated.\u00a0The need for foreplay for you and your partner is the same as when you have not taken any medication for\u00a0erectile dysfunction.<\/li><li>Urinary tract symptoms are associated with a common condition called\u00a0benign\u00a0prostatic hyperplasia.\u00a0This is when the prostate gland becomes larger with increasing age.\u00a0Symptoms include difficulty passing water, a feeling of not being able to empty the bladder, and having to pass water more often, even at night.\u00a0Tadalafil improves blood flow and relaxes the muscles in the prostate and bladder, which can reduce symptoms of\u00a0benign\u00a0prostatic hyperplasia.\u00a0Tadalafil has shown an effect on these urinary tract symptoms as early as 1\u20132 weeks after starting treatment.<\/li><\/ul>\n\n\n\n<p>Tadalafil contained in Tadalafil Orion may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Tadalafil Orion<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Tadalafil Orion<\/h2>\n\n\n\n<p>Do not take Tadalafil Orion if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>are allergic to tadalafil or any of the other ingredients of this medicine (listed in section 6).<\/li><li>are taking medicines containing\u00a0organic nitrates\u00a0or nitric oxide donors such as amyl nitrite.\u00a0These medicines (&#8220;nitrates&#8221;) are used to treat angina (chest pain).\u00a0Tadalafil Orion has been shown to increase the effect of these drugs.\u00a0If you are taking any form of nitrates or if you are not sure, talk to your doctor.<\/li><li>have a serious heart condition or have recently had a heart attack within the last 90 days.<\/li><li>recently had a stroke\u00a0within\u00a0the last 6 months.<\/li><li>have low\u00a0blood pressure\u00a0or uncontrolled high\u00a0blood pressure.<\/li><li>have ever lost sight due to non-arteritic anterior ischemic optic neuropathy (NAION), the so-called &#8220;stroke in the eye&#8221;.<\/li><li>taking riociguat.\u00a0This medicine is used to treat\u00a0pulmonary\u00a0arterial\u00a0hypertension\u00a0(ie high\u00a0blood pressure\u00a0in the lungs) and\u00a0chronic\u00a0thromboembolic\u00a0pulmonary\u00a0hypertension\u00a0(ie high\u00a0blood pressure\u00a0in the lungs due to blood clots).\u00a0PDE5 inhibitors, such as Tadalafil Orion, have been shown to increase the blood pressure-lowering effect of this medicine.\u00a0If you are taking riociguat or if you are not sure, talk to your doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Tadalafil Orion.<\/p>\n\n\n\n<p>Keep in mind that sexual intercourse poses a possible risk to patients with heart disease, as it puts more strain on the heart than usual.&nbsp;If you have heart problems, tell your doctor.<\/p>\n\n\n\n<p>As\u00a0benign\u00a0prostatic hyperplasia\u00a0and prostate cancer can have the same symptoms, your doctor will investigate you regarding prostate cancer before starting treatment with Tadalafil Orion for\u00a0benign\u00a0prostatic hyperplasia.\u00a0Tadalafil Orion is not a treatment for prostate cancer.<\/p>\n\n\n\n<p>Before taking the tablets, tell your doctor if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sickle cell anemia&nbsp;(abnormal&nbsp;red blood cells&nbsp;).<\/li><li>multiple&nbsp;myeloma&nbsp;(cancer of the&nbsp;bone marrow&nbsp;).<\/li><li>leukemia&nbsp;(blood cell cancer).<\/li><li>deformed penis.<\/li><li>severe liver disease.<\/li><li>severe kidney disease.<\/li><\/ul>\n\n\n\n<p>It is not known whether Tadalafil Orion is effective in patients who have undergone:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pelvic surgery.<\/li><li>surgery where part or all of the prostate gland is removed and where the nerves are not preserved (radical non-nerve-sparing&nbsp;prostatectomy&nbsp;).<\/li><\/ul>\n\n\n\n<p>If you experience a sudden decrease or loss of vision, stop taking Tadalafil Orion and contact your doctor immediately.<\/p>\n\n\n\n<p>Impaired hearing or sudden hearing loss has been noted in some patients taking tadalafil.&nbsp;Although it is not known whether the events are related to tadalafil, you should stop taking Tadalafil Orion and contact your doctor immediately if you develop hearing impairment or sudden hearing loss.<\/p>\n\n\n\n<p>Tadalafil Orion is not intended for use by women.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Tadalafil Orion is not intended for use by children and adolescents under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tadalafil Orion<\/h2>\n\n\n\n<p>Always tell your doctor if you are taking, have recently taken, or might take any other medicines.\u00a0Do not take Tadalafil Orion if you are already taking nitrates.<\/p>\n\n\n\n<p>Some medicines can be affected by Tadalafil Orion or affect how well Tadalafil Orion will work.&nbsp;Tell your doctor or pharmacist if you are already taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>alpha-blockers (used to treat high\u00a0blood pressure\u00a0or urinary tract symptoms related to\u00a0benign\u00a0prostatic hyperplasia\u00a0).<\/li><li>any other medicine to treat high\u00a0blood pressure.<\/li><li>riociguat.<\/li><li>a 5-alpha reductase inhibitor (used to treat\u00a0benign\u00a0prostatic hyperplasia\u00a0).<\/li><li>medicines such as ketoconazole tablets (to treat fungal infections) and\u00a0protease inhibitors\u00a0to treat\u00a0AIDS\u00a0or\u00a0HIV\u00a0infection.<\/li><li>phenobarbital,\u00a0phenytoin\u00a0and carbamazepine (antiepileptic drugs).<\/li><li>rifampicin, erythromycin, clarithromycin, or itraconazole.<\/li><li>other treatments for\u00a0erectile dysfunction.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Tadalafil Orion with drink and alcohol<\/h2>\n\n\n\n<p>For information on the effect of alcohol, see section 3. Grapefruit juice can affect how well Tadalafil Orion will work and should be taken with caution.&nbsp;Talk to your doctor for more information.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fertility<\/h2>\n\n\n\n<p>When dogs were treated, a decrease in sperm was seen.\u00a0A decrease in sperm has been seen in some men.\u00a0It is unlikely that this decrease in sperm would lead to\u00a0infertility.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Dizziness has been reported by some of the men taking Tadalafil Orion in\u00a0clinical studies.\u00a0Feel how you react to the tablets before driving or using machinery.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tadalafil Orion contains lactose<\/h2>\n\n\n\n<p>If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Tadalafil Orion contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8220;sodium-free&#8221;.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Tadalafil Orion<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Tadalafil Orion tablets are taken by mouth and are intended for men only.&nbsp;Swallow the tablet whole with a little water.&nbsp;The tablet can be taken regardless of a meal.<\/p>\n\n\n\n<p>Alcohol intake can temporarily lower your\u00a0blood pressure.\u00a0If you have taken or plan to take Tadalafil Orion, avoid consuming large amounts of alcohol (0.8 per mille or more in the blood) as this may increase the risk of dizziness when standing up.<\/p>\n\n\n\n<p><strong>For the treatment of&nbsp;erectile dysfunction<\/strong><\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;is one<\/strong>&nbsp;5 mg tablet a day, taken at about the same time each day.&nbsp;Your doctor may change the&nbsp;dose&nbsp;from one to 2.5 mg depending on how Tadalafil Orion works for you.&nbsp;You will then be prescribed another product containing tadalafil 2.5 mg.<\/p>\n\n\n\n<p>Do not take Tadalafil Orion more than once per day.<\/p>\n\n\n\n<p>When you take Tadalafil Orion once a day, you can get\u00a0an erection\u00a0at any time during the 24 hours, if you are sexually stimulated.\u00a0The daily\u00a0dosing\u00a0of Tadalafil Orion may be suitable for men who have sexual intercourse two or more times per week.<\/p>\n\n\n\n<p>It is important to remember that Tadalafil Orion has no effect if you are not sexually stimulated.\u00a0The need for foreplay for you and your partner is the same as when you have not taken any medication for\u00a0erectile dysfunction.<\/p>\n\n\n\n<p>Alcohol intake can affect your ability to get\u00a0an erection.\u00a0<\/p>\n\n\n\n<p><strong>For the treatment of&nbsp;benign&nbsp;prostatic hyperplasia<\/strong><\/p>\n\n\n\n<p>Dose\u00a0one is one 5 mg tablet a day, taken at about the same time each day.\u00a0If you have\u00a0benign\u00a0prostatic hyperplasia\u00a0and\u00a0erectile dysfunction, the\u00a0dose\u00a0is still one 5 mg tablet a day.<\/p>\n\n\n\n<p>Do not take Tadalafil Orion more than once daily.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Tadalafil Orion &nbsp;<\/h2>\n\n\n\n<p>Contact your doctor.\u00a0You may experience\u00a0the side effects\u00a0described in section 4.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Tadalafil Orion<\/h2>\n\n\n\n<p>Take your&nbsp;dose&nbsp;as soon as you remember but do not take a double&nbsp;dose&nbsp;to make up for a missed tablet.&nbsp;You should not take Tadalafil Orion more often than once a day.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0Side effects\u00a0are usually mild or moderate.<\/p>\n\n\n\n<p><strong>If you experience any of the following\u00a0side effects, stop using the medicine and see a doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions with rash (frequency less common).<\/li><li>chest pain &#8211; do not use nitrates but see a doctor immediately (frequency less common).<\/li><li>priapism, prolonged and possibly painful&nbsp;erection&nbsp;after taking Tadalafil Orion (frequency rare).&nbsp;If you get&nbsp;an erection&nbsp;that lasts continuously for more than 4 hours, consult a doctor immediately.<\/li><li>sudden loss of vision (frequency rare).<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache, back pain, muscle pain, pain in arms and legs, facial flushing, nasal congestion, and indigestion.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness, stomach pain, nausea, vomiting, reflux, blurred vision, pain in the eyes, difficulty breathing, presence of blood in the urine, prolonged\u00a0erection, palpitations, rapid heartbeat, high\u00a0blood pressure, low\u00a0blood pressure, nosebleeds,\u00a0tinnitus\u00a0(sound in the ears without an external sound source), swollen hands, feet or ankles, and tiredness.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fainting, seizures and temporary memory loss, swollen eyelids, red eyes, sudden deterioration or loss of hearing, rash (itchy red small blisters on the skin), bleeding from the penis, presence of blood in semen, and increased sweating.<\/li><\/ul>\n\n\n\n<p>Heart attack and stroke have been reported rarely in men taking Tadalafil Orion.&nbsp;Most had known heart problems before taking the drug.<\/p>\n\n\n\n<p>Partial, temporary, or permanent visual impairment or loss of vision in one or both eyes has been reported rarely.<\/p>\n\n\n\n<p><strong>A few more rare\u00a0side effects<\/strong>,\u00a0which were not observed in\u00a0clinical trials, have been reported by men taking Tadalafil Orion.\u00a0These are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>migraine, facial swelling, severe\u00a0allergic reaction\u00a0causing swelling\u00a0of\u00a0the face or throat, severe skin rash, disturbances in blood flow to the eyes, irregular heartbeat, angina pectoris, and sudden cardiac death.<\/li><\/ul>\n\n\n\n<p>The side effect&nbsp;of dizziness has been reported more often in men over 75 years of age taking Tadalafil Orion.&nbsp;Diarrhea has been reported more often in men over 65 years of age taking Tadalafil Orion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tadalafil Orion<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton, on the blister pack, or on the can label after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tadalafil.\u00a0One film-coated tablet contains 5 mg of tadalafil.<\/li><li>Other ingredients are Tablet core:\u00a0copovidone, macrogol glycerol hydroxy stearate,\u00a0lactose monohydrate,\u00a0colloidal\u00a0anhydrous silica, microcrystalline cellulose, croscarmellose sodium, magnesium stearate film<em> coating:<\/em>\u00a0hypromellose, titanium dioxide (E171), talc (E553b), iron oxide yellow (E172), triacetin.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Film-coated tablet.<\/p>\n\n\n\n<p>Light yellow, oval film-coated tablet marked &#8220;5&#8221; on one side and &#8220;TL&#8221; on the other side.<\/p>\n\n\n\n<p>Tadalafil Orion film-coated tablets are packed in blister packs of transparent PVC\/PVdC and aluminum foil and HDPE cans.<\/p>\n\n\n\n<p>Blister packs: 4, 8, 12, 14, 28, 30, 56, 84 and 90 film-coated tablets.<\/p>\n\n\n\n<p>Cans: 100 and 250 film-coated tablets<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Orion Corporation<\/p>\n\n\n\n<p>Orion Indie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>APL Swift Services (Malta) Limited<\/p>\n\n\n\n<p>HF26, Hal Far Industrial Estate, Hal Far, Birzebbugia, BBG 3000<\/p>\n\n\n\n<p>Malta<\/p>\n\n\n\n<p>Milpharm Limited<\/p>\n\n\n\n<p>Ares Block, Odyssey Business Park, West End Road, Ruislip HA4 6QD<\/p>\n\n\n\n<p>UK<\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Orion Intie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Joensuunkatu 7<\/p>\n\n\n\n<p>FI-24100 Salo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>Generis Farmac\u00eautica SA<\/p>\n\n\n\n<p>Rua Jo\u00e3o de Deus, no. 19<\/p>\n\n\n\n<p>Venda Nova, 2700-487 Amadora<\/p>\n\n\n\n<p>Portugal<\/p>\n\n\n\n<p>For further information about this medicine, contact your local representative:<\/p>\n\n\n\n<p>Orion Pharma AB, Danderyd, medinfo@orionpharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tadalafil Orion contains the active substance tadalafil which belongs to a group of medicines called\u00a0phosphodiesterase\u00a0type 5 inhibitors.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[7298,25107,25111,25110,7300,7301,7299,25108,11676,25109],"class_list":["post-24195","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-tadalafil","tag-tadalafil-orion","tag-tadalafil-orion-side-effects","tag-tadalafil-orion-tablet","tag-tadalafil-side-effects","tag-tadalafil-tablet","tag-what-is-tadalafil","tag-what-is-tadalafil-orion","tag-what-tadalafil-is-used-for","tag-what-tadalafil-orion-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24195"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24195\/revisions"}],"predecessor-version":[{"id":24227,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24195\/revisions\/24227"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}