{"id":23995,"date":"2022-08-13T08:34:45","date_gmt":"2022-08-13T08:34:45","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23995"},"modified":"2022-08-15T09:28:45","modified_gmt":"2022-08-15T09:28:45","slug":"sunosi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sunosi\/","title":{"rendered":"Sunosi &#8211; Solriamfetol uses, dose and side effects"},"content":{"rendered":"\n<p>75 mg 150 mg&nbsp;film-coated tablets<br>solriamfetol<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sunosi is and what it is used for<\/h2>\n\n\n\n<p>Sunosi contains the active substance solriamfetol.&nbsp;Solriamfetol increases the amount of the natural substances&nbsp;dopamine&nbsp;and&nbsp;norepinephrine&nbsp;in the brain.&nbsp;Sunosi helps you stay awake and less sleepy.<\/p>\n\n\n\n<p>It is used<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>to adults with\u00a0narcolepsy, a condition that makes you feel very sleepy at any time, suddenly and unexpectedly.\u00a0Some patients with\u00a0narcolepsy\u00a0also have symptoms of\u00a0cataplexy\u00a0(when the muscles become weaker in connection with emotions such as anger, fear, laughter, or surprise. which Can sometimes lead to collapse).<\/li><li>to increase alertness and reduce excessive daytime sleepiness (EDS) in adult patients with obstructive\u00a0sleep apnea\u00a0(OSA) whose EDS has not been adequately treated with primary OSA treatment, such as continuous positive airway pressure (CPAP).<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Sunosi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Sunosi if you<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>are allergic to solriamfetol or any of the other ingredients of this medicine (listed in section 6)<\/li><li>have had a heart attack in the past year<\/li><li>have serious heart problems, e.g.\u00a0new chest pain or chest pain that lasts longer or is more severe than usual, high\u00a0blood pressure\u00a0that cannot be controlled with medicine, severely irregular heartbeat, or other serious heart problems<\/li><li>are taking a type of medicine called a\u00a0monoamine oxidase inhibitor\u00a0(\u00a0MAO inhibitor\u00a0) for depression or\u00a0Parkinson&#8217;s disease, or have taken\u00a0MAO inhibitors\u00a0in the last 14 days.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Sunosi if you have or have had<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>mental health problems, such as\u00a0psychosis\u00a0(disturbed perception of reality) and severe mood swings (\u00a0bipolar disorder\u00a0)<\/li><li>heart problems, heart attack, or\u00a0stroke<\/li><li>high\u00a0blood pressure<\/li><li>alcoholism or any drug or drug abuse or dependence<\/li><li>an eye disease called\u00a0narrow-angle glaucoma.<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist before starting treatment if any of the above applies to you.\u00a0Sonos may make some of these problems worse.\u00a0The doctor will do checks to see how the medicine affects you.<\/p>\n\n\n\n<p>Sonos does not replace your usual OSA treatment, e.g.\u00a0CPAP.\u00a0You should continue that treatment while taking Sunosi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Sonos is not recommended for children and adolescents under 18 years of age.\u00a0Safety and efficacy in this age group are not yet known.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sunosi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Do not retake Sunosi<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you are taking a medicine called a\u00a0monoamine oxidase inhibitor\u00a0(\u00a0MAO inhibitor\u00a0) for depression or\u00a0Parkinson&#8217;s disease, or have taken\u00a0MAO inhibitors\u00a0in the last 14 days.\u00a0MAO inhibitors\u00a0together with Sunosi can raise\u00a0blood pressure\u00a0et.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor or pharmacist if you are taking medicines that can increase\u00a0blood pressure\u00a0or\u00a0pulse\u00a0(heart rate), or if you are taking dopaminergic substances (eg pramipexole,\u00a0levodopa,\u00a0or methylphenidate) used to treat\u00a0Parkinson&#8217;s disease, depression, restless legs syndrome (restless legs) and\u00a0ADHD.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>Sonos should not be used during pregnancy or in women of childbearing potential who are not using effective contraception.<\/p>\n\n\n\n<p>Do not take Sunosi if you are breastfeeding.\u00a0You and your doctor must decide whether to stop breastfeeding or to stop or withhold treatment with Sunosi after considering the benefit of breastfeeding for you and your baby and the benefit of treatment for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>You may feel dizzy or have difficulty concentrating, so take special care when driving any vehicle or using machinery.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you are not sure how the underlying disease or this medicine affects you when it comes to activities that require close attention, e.g.&nbsp;driving or using machines<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>at the beginning of treatment<\/li><li>if your&nbsp;dose&nbsp;changes.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Sunosi<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How much Sunosi should you take?<\/h2>\n\n\n\n<p>The doctor will tell you what&nbsp;dose&nbsp;of Sunosi you should take.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Treatment for\u00a0narcolepsy\u00a0normally starts with 75 mg once daily, to be taken in the morning when you wake up.\u00a0Some patients may need a starting dose of 150 mg.\u00a0The doctor will tell you if this applies to you.\u00a0The doctor may give you a lower\u00a0dose\u00a0of 37.5 mg.\u00a0You get this\u00a0dose\u00a0by dividing a 75 mg tablet.\u00a0The tablet should be split in the score.<\/li><li>Treatment for OSA usually starts with 37.5 mg once daily, to be taken in the morning when you wake up.\u00a0You get this\u00a0dose\u00a0by dividing a 75 mg tablet.\u00a0The tablet should be split in the score.<\/li><li>After at least 3 days of treatment, the doctor can increase your daily\u00a0dose\u00a0to the\u00a0dose\u00a0that is most suitable for you.<\/li><\/ul>\n\n\n\n<p>The recommended maximum&nbsp;dose&nbsp;of Sunosi is 150 mg daily.<\/p>\n\n\n\n<p><strong>Elderly (over 65 years)<\/strong><\/p>\n\n\n\n<p>Take the usual&nbsp;dose&nbsp;once unless you have kidney problems (see below \u201cPatients with kidney problems\u201d).<\/p>\n\n\n\n<p><strong>Patients with kidney problems<\/strong><\/p>\n\n\n\n<p>If you have kidney problems, your doctor may need to change your\u00a0dose.<\/p>\n\n\n\n<p><strong>How to take Sunosi<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sonos should be swallowed.<\/li><li>Take Sunosi by mouth in the morning when you wake up.<\/li><li>You can take Sunosi with food or between meals.<\/li><\/ul>\n\n\n\n<p><strong>How long take Sunosi<\/strong><\/p>\n\n\n\n<p>Continue taking Sunosi for as long as your doctor has prescribed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Sunosi<\/h2>\n\n\n\n<p>The following symptoms were seen when a patient received 900 mg of Sunosi (6 times the highest daily\u00a0dose): uncontrollable movements (\u00a0tardive dyskinesia\u00a0) and a feeling of restlessness and difficulty staying still (\u00a0akathisia\u00a0).\u00a0The symptoms disappeared when treatment with Sunosi was discontinued.<\/p>\n\n\n\n<p>Contact a doctor or the nearest emergency department immediately for advice.&nbsp;Take this leaflet and any tablets you have left with you.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Sunosi<\/h2>\n\n\n\n<p>If you forget to take the medicine at the usual time, you can still take it if it is more than 9 hours until bedtime.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Sunosi<\/h2>\n\n\n\n<p>Talk to your doctor before you stop taking Sunosi.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache.<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anxiety, difficulty sleeping, irritability, dizziness, nervousness, profuse sweating<\/li><li>fast or irregular\u00a0pulse, so-called palpitations, discomfort in the chest<\/li><li>high\u00a0blood pressure<\/li><li>nausea, diarrhea, stomach pain, constipation, vomiting<\/li><li>cough, teeth grinding\/clenching,\u00a0dry mouth<\/li><li>decreased appetite.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>agitation, restlessness, concentration difficulties,\u00a0tremors<\/li><li>an increased\u00a0heart rate\u00a0that is much higher than normal<\/li><li>shortness of breath<\/li><li>pains in the chest<\/li><li>thirst<\/li><li>weight loss.<\/li><\/ul>\n\n\n\n<p>Skin rash,\u00a0hives,\u00a0and\u00a0itching\u00a0have also been reported.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sunosi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and can\/blister after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Blister cards: No special storage instructions.<\/p>\n\n\n\n<p>Cans: After opening, they should be used within 4 months.&nbsp;Seal the jar well.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is solriamfetol.<\/p>\n\n\n\n<p>SunOS 75 mg film-coated tablets<\/p>\n\n\n\n<p>Each tablet contains solriamfetol hydrochloride equivalent to 75 mg solriamfetol.<\/p>\n\n\n\n<p>SunOS 150 mg film-coated tablets<\/p>\n\n\n\n<p>Each tablet contains solriamfetol hydrochloride equivalent to 150 mg solriamfetol.<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>Tablet core: hydroxypropyl cellulose, magnesium stearate<\/p>\n\n\n\n<p>Film coating: polyvinyl alcohol, macrogol, talc, titanium dioxide (E171), yellow iron oxide (E172).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Film-coated tablet<\/p>\n\n\n\n<p>SunOS 75 mg film-coated tablets<\/p>\n\n\n\n<p>Yellow to dark yellow\/orange oblong tablet with &#8220;75&#8221; debossed on one side and scored on the other side.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n<p>SunOS 150 mg film-coated tablets<\/p>\n\n\n\n<p>Yellow oblong tablet with &#8220;150&#8221; embossed on one side.<\/p>\n\n\n\n<p>Sonos is available in blister packs of 7 x 1 film-coated tablet in perforated single-dose blisters of PVC\/PCTFE\/aluminum, 28 or 56 film-coated tablets, and in cans of 30 or 100 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Jazz Pharmaceuticals Ireland Ltd<\/p>\n\n\n\n<p>5&nbsp;<sup>th<\/sup>&nbsp;Floor<\/p>\n\n\n\n<p>Waterloo Exchange<\/p>\n\n\n\n<p>Waterloo Road<\/p>\n\n\n\n<p>Dublin<\/p>\n\n\n\n<p>D04 E5W7<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p>Phone: +353 1 968 1631<\/p>\n\n\n\n<p>(local telephone number within Ireland)<\/p>\n\n\n\n<p>(outside the Republic of Ireland international call charges may apply)<\/p>\n\n\n\n<p>Email: medinfo-int@jazzpharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sunosi contains the active substance solriamfetol.\u00a0Solriamfetol increases the amount of the natural substances\u00a0dopamine\u00a0and\u00a0norepinephrine\u00a0in the brain.\u00a0Sunosi helps you stay awake and less sleepy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24968,24971,24966,24967,24970,24972,24964,24973,24965,24969],"class_list":["post-23995","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-solriamfetol","tag-benefits-of-sunosi","tag-solriamfetol","tag-solriamfetol-side-effects","tag-sunosi","tag-sunosi-side-effects","tag-what-is-solriamfetol","tag-what-is-sunosi","tag-what-solriamfetol-is-used-for","tag-what-sunosi-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23995"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23995\/revisions"}],"predecessor-version":[{"id":24021,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23995\/revisions\/24021"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23995"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23995"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}