{"id":23900,"date":"2022-08-11T15:37:00","date_gmt":"2022-08-11T15:37:00","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23900"},"modified":"2022-08-12T12:08:25","modified_gmt":"2022-08-12T12:08:25","slug":"sumatriptan-apofree","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sumatriptan-apofree\/","title":{"rendered":"Sumatriptan Apofree &#8211; Sumatriptan uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg&nbsp;film-coated tablet<br>sumatriptan<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sumatriptan Apofri is and what it is used for<\/h2>\n\n\n\n<p>Sumatriptan Apofri belongs to a group of medicines called triptans, which are used to treat migraine headaches.<\/p>\n\n\n\n<p>Migraine symptoms can be caused by a temporary dilation of the blood vessels in the head.\u00a0This medicine reduces the dilation of these blood vessels.\u00a0This helps the headache disappear and relieves other migraine symptoms such as nausea, vomiting, and sensitivity to light and sound.<\/p>\n\n\n\n<p>Sumatriptan Apofri is used to treat migraine attacks with or without\u00a0aura\u00a0(a premonition that usually consists of visual disturbances such as flashes, zigzag lines, stars, or waves).<\/p>\n\n\n\n<p>Sumatriptan Apofri should only be used when you have signs or symptoms of a migraine attack.<\/p>\n\n\n\n<p>Migraine headaches are usually of moderate to severe\u00a0intensity, unilateral (but can switch sides between attacks), and have a pulsating character.\u00a0Symptoms such as nausea, sometimes vomiting, and significant sensitivity to light and sound are common in\u00a0migraines.<\/p>\n\n\n\n<p>Sumatriptan Apofri is not intended for the treatment of other types of headache, e.g.&nbsp;tension headache.<\/p>\n\n\n\n<p>Sumatriptan contained in Sumatriptan Apofri may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Sumatriptan Apofri<\/h2>\n\n\n\n<p>Sumatriptan Apofri should only be used by you who have been diagnosed with&nbsp;migraine&nbsp;confirmed by a doctor.<\/p>\n\n\n\n<p>You probably have a&nbsp;migraine&nbsp;if you have recurring headaches such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>has a pulsating character and is unilateral,<\/li><li>has moderate to the strong\u00a0intensity\u00a0and lasts for 4-72 hours,<\/li><li>worsens with normal physical activity (eg walking or climbing stairs)<\/li><li>affects your ability to concentrate and your daily tasks.<\/li><\/ul>\n\n\n\n<p>Migraines&nbsp;can be accompanied by other symptoms such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea, sensitivity to light and sound,<\/li><li>aura symptoms (e.g. visual field loss, zigzag patterns or flashes in the&nbsp;visual field&nbsp;et), and more rarely numbness or speech difficulties.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Sumatriptan Apofri<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sumatriptan or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have or have had heart problems, such as a heart attack, angina (chest pain brought on by exercise or exertion), Prinzmetal&#8217;s angina (chest pain that comes on at rest), or have had heart-related symptoms such as shortness of breath or tightness in the chest<\/li><li>if you have problems with blood circulation in the hands and feet (\u00a0peripheral\u00a0vascular disease)<\/li><li>if you have had a\u00a0stroke\u00a0(&#8220;stroke&#8221;) or bleeding in the brain (\u00a0cerebrovascular\u00a0disease) or if you have had a transient disturbance of the blood supply to the brain (\u00a0TIA\u00a0)<\/li><li>if you have high\u00a0blood pressure<\/li><li>if you have severely impaired liver function<\/li><li>if you are taking medicines containing\u00a0ergotamine\u00a0or ergotamine derivatives (migraine medicines such as methysergide) or triptans (5\u2011hydroxytryptamine (5\u2011HT\u00a0<sub>1<\/sub>\u00a0),\u00a0receptor agonists\u00a0such as almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan or zolmitriptan) These must not be taken at the same time as Sumatriptan Apofri (see also &#8220;Other medicines and Sumatriptan Apofri&#8221;).<\/li><li>if you are currently taking\u00a0monoamine oxidase inhibitors\u00a0(MAOIs) (eg moclobemide for depression or\u00a0selegiline\u00a0for\u00a0Parkinson&#8217;s disease\u00a0) Sumatriptan Apofri must not be used within two weeks of stopping treatment with MAOIs.\u00a0See also &#8220;Other medicines and Sumatriptan Apofri&#8221; below.<\/li><\/ul>\n\n\n\n<p>If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using this medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Sumatriptan Apofri.<\/p>\n\n\n\n<p>Before you start using Sumatriptan Apofri, talk to your doctor if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Have\u00a0diabetes, especially if you are a postmenopausal woman or a man over 40.\u00a0A medical examination should take place before treatment begins.<\/li><li>Are a heavy smoker or use products containing nicotine (\u00a0patches\u00a0or\u00a0gum\u00a0), especially if you are a man over 40 or a woman who has passed menopause.\u00a0A medical examination should take place before treatment begins.<\/li><li>Have had seizures\/convulsions or are prone to seizures\/convulsions.\u00a0Sumatriptan Apofri may increase the risk of seizures.<\/li><li>Has reduced liver or kidney function.\u00a0The doctor may adjust your\u00a0dose.<\/li><li>Are allergic (hypersensitive) to certain\u00a0antibiotics\u00a0(\u00a0sulfonamides\u00a0).\u00a0In this case, you may also be allergic to Sumatriptan Apofri.\u00a0If you know that you are allergic to an\u00a0antibiotic\u00a0(even if you are not sure that it is a sulfonamide), consult your doctor or pharmacist before using this medicine.<\/li><\/ul>\n\n\n\n<p>This medicine may only be used if you have been diagnosed with a &#8220;migraine&#8221; and other factors have been ruled out.\u00a0Some forms of\u00a0migraine\u00a0cannot be treated with sumatriptan.<\/p>\n\n\n\n<p>After taking this medicine, you may feel pain in your chest and a feeling of pressure for a short time.&nbsp;These symptoms can be quite intense and radiate up to the throat.&nbsp;In very rare cases this can be caused by effects on the heart.&nbsp;Therefore, you should contact a doctor if the symptoms do not disappear.<\/p>\n\n\n\n<p>Overuse of this medication may cause\u00a0chronic, daily headaches or worsening headaches.\u00a0It may be necessary to discontinue treatment with Sumatriptan Apofri.\u00a0Consult your doctor if this is right for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sumatriptan Apofri<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Interaction\u00a0means that medicines used at the same time can affect each other&#8217;s effects and\/or\u00a0side effects.\u00a0The following may also apply to medicines that you have used in the past or will use shortly.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Medicines containing\u00a0ergotamine\u00a0(migraine medicine) or other triptans.\u00a0These must not be taken at the same time as Sumatriptan Apofri (see also &#8220;Do not take Sumatriptan Apofri&#8221;):<ul><li>After taking medicines containing\u00a0ergotamine, you should wait at least 24 hours before taking Sumatriptan Apofri.<\/li><li>After you have taken Sumatriptan Apofri, you should wait at least 6 hours before taking medicines containing\u00a0ergotamine\u00a0and at least 24 hours before taking medicines containing other triptans.<\/li><\/ul><\/li><li>Monoamine oxidase inhibitors\u00a0(MAOIs) (eg moclobemide for depression or\u00a0selegiline\u00a0for\u00a0Parkinson&#8217;s disease\u00a0).<ul><li>You must not take Sumatriptan Apofri within two weeks of stopping using MAOIs.<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Use of triptans together with antidepressants such as selective serotonin reuptake inhibitors (\u00a0SSRIs\u00a0) and\u00a0serotonin\u00a0and norepinephrine reuptake inhibitors (\u00a0SNRIs\u00a0) may cause serotonin syndrome (a collection of symptoms that may include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle twitching, tremors, palpitations, and tremors).\u00a0If you get these symptoms, tell your doctor.<\/li><li>There is a risk that the simultaneous use of sumatriptan and lithium (for manic\/depressive (bipolar) disorders) may cause serotonin syndrome.<\/li><li>With the simultaneous use of natural remedies containing St. John&#8217;s\u00a0wort\u00a0(\u00a0<em>Hypericum perforatum<\/em>\u00a0),\u00a0side effects\u00a0may occur more often.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>Sumatriptan Apofri should only be used during pregnancy under the\u00a0prescription\u00a0of a doctor.\u00a0Sumatriptan Apofri should only be used during pregnancy if the positive effects for the mother are greater than the potential risk to the fetus.<\/p>\n\n\n\n<p>Sumatriptan passes into breast milk.\u00a0Avoid breastfeeding for 12 hours after taking Sumatriptan Apofri to reduce the amount of medicine the baby gets.\u00a0During this time, the breast milk should be pumped out and thrown away.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>No studies on the ability to drive and use machines have been performed.<\/p>\n\n\n\n<p>Drowsiness may occur as a result of&nbsp;migraine&nbsp;or its treatment with sumatriptan and this may affect the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Sumatriptan Apofri contains lactose<\/h2>\n\n\n\n<p>If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicinal product contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per film-coated tablet, i.e.&nbsp;is almost &#8220;sodium-free&#8221;.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Sumatriptan Apofri<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sumatriptan Apofri should be taken at the first sign of a migraine attack, but can also be taken during an ongoing attack.<\/li><li>Sumatriptan Apofri should not be used preventively (prophylactically).<\/li><li>Do not take more than 2 tablets per 24-hour period.<\/li><li>Do not take more than 2 tablets during the same migraine attack.<\/li><\/ul>\n\n\n\n<p><strong>Dosage:<\/strong><\/p>\n\n\n\n<p><em>Adults (18-65 years):<\/em><\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0for adults is 1 tablet of 50 mg for migraine attacks.\u00a0No more than 2 tablets in 24 hours.<\/p>\n\n\n\n<p>Take the tablet with water, preferably as soon as possible after the migraine attack starts.&nbsp;The tablets must not be chewed or crushed.<\/p>\n\n\n\n<p><em>Children and young people:<\/em><\/p>\n\n\n\n<p>Sumatriptan Apofri is not recommended for children and adolescents under the age of 18.<\/p>\n\n\n\n<p><em>Elderly people (over the age of 65):<\/em><\/p>\n\n\n\n<p>Sumatriptan Apofri is not recommended for adults over 65 years of age.<\/p>\n\n\n\n<p>If the migraine symptoms\u00a0<strong>are relieved<\/strong>\u00a0after the first\u00a0dose\u00a0(1 tablet) but later return, another 1 tablet can be taken.\u00a0You must wait at least 2 hours after taking the first\u00a0dose\u00a0before you can take the second\u00a0dose.<\/p>\n\n\n\n<p>If the migraine symptoms\u00a0<strong>are not relieved<\/strong>\u00a0after the first\u00a0dose\u00a0and the medication is not effective, do\u00a0<strong>not<\/strong>\u00a0take another\u00a0dose\u00a0during the same migraine attack.\u00a0The next time you get a\u00a0migraine, you can try Sumatriptan Apofri again.<\/p>\n\n\n\n<p>You must contact a doctor if symptoms worsen or do not improve within 3 days.<\/p>\n\n\n\n<p>Sumatriptan Apofri should only be used to relieve migraine symptoms.&nbsp;Do not take the medicine to try to prevent a seizure.&nbsp;Do not take the medicine until you are sure that it is a&nbsp;migraine&nbsp;and not a regular headache.<\/p>\n\n\n\n<p>If you feel that Sumatriptan Apofri does not provide any relief, it may mean that you do not have a\u00a0migraine.\u00a0Talk to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Sumatriptan Apofri is not recommended for children and adolescents under the age of 18.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Sumatriptan Apofri&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>Side effects&nbsp;such as those mentioned under &#8220;Potential side effects&#8221; may occur.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Sumatriptan Apofri<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Sumatriptan Apofri<\/h2>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop taking Sumatriptan Apofri and contact your doctor immediately if you experience any of the following side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe\u00a0allergic reaction\u00a0(so-called\u00a0anaphylactic reaction\u00a0) with symptoms such as swelling of the face, tongue, or throat;\u00a0difficulty swallowing;\u00a0hives\u00a0and breathing difficulties, and drop in blood pressure.\u00a0<\/li><li>Seizures (usually in people who have or have had\u00a0epilepsy\u00a0).<\/li><li>Vascular spasm (pain in the chest, often brought on by exertion), heart attack, or spasm in the blood vessels of the heart.<\/li><li>Inflammation\u00a0in the large intestine due to reduced blood flow in the intestine.\u00a0This is a serious condition that can manifest as acute cramping stomach pains and diarrhea.<\/li><\/ul>\n\n\n\n<p>The above&nbsp;side effects&nbsp;have been reported but occur in an unknown number of users.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that may occur:<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(affects more than 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness, drowsiness or feeling of warmth, sensory disturbance<\/li><li>Transient increase in\u00a0blood pressure\u00a0et soon after treatment,\u00a0flushing<\/li><li>Shortness of breath<\/li><li>Nausea, vomiting<\/li><li>A feeling of heaviness, tightness, pain, or pressure in any part of the body including the throat or chest, muscle pain (\u00a0myalgia\u00a0)<\/li><li>Pain, heat, or cold sensation<\/li><li>Weakness and tiredness (exhaustion)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(affects less than 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drowsiness (sleepiness)<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(affects less than 1 in 10,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Impaired liver function<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurring in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic skin reaction with\u00a0itching<\/li><li>Tremors<\/li><li>Movement disorder that can cause abnormal movements or abnormal posture (\u00a0dystonia\u00a0)<\/li><li>Impaired vision, e.g.\u00a0double vision, flickering, and sometimes loss of vision with permanent visual impairment.\u00a0Visual disturbances can also occur as a result of the migraine attack itself.<\/li><li>Slow heartbeats, fast heartbeats, organ-bound heartbeats, palpitations.\u00a0Transient ischemic\u00a0EKG\u00a0changes, seen during\u00a0EKG\u00a0examination.<\/li><li>Reduced blood flow to the arms and legs, resulting in pale or bluish fingers and toes<\/li><li>If you have recently injured yourself or if you have inflammation\u00a0(such as rheumatism or\u00a0inflammation\u00a0of the colon), you may experience pain or worsening pain at the site of the injury or\u00a0inflammation.<\/li><li>Difficulty swallowing<\/li><li>Diarrhea<\/li><li>Drop in blood pressure<\/li><li>Stiff neck<\/li><li>Joint pain<\/li><li>Anxiety<\/li><li>Increased sweating<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sumatriptan Apofri<\/h2>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton after Exp or EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is sumatriptan succinate corresponding to 50 mg of sumatriptan per tablet.<\/p>\n\n\n\n<p><em>Other ingredients are:<\/em><\/p>\n\n\n\n<p><em>Tablet core:\u00a0<\/em>lactose monohydrate, microcrystalline cellulose (E460), pregelatinized maize starch, croscarmellose sodium, magnesium stearate (E470b).<\/p>\n\n\n\n<p><em>Coating:<\/em>&nbsp;hypromellose (E464), titanium dioxide (E171), talc (E553b), red iron oxide (E172), yellow iron oxide (E172), macrogol<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Sumatriptan Apofri 50 mg film-coated tablets are peach-colored, capsule-shaped, biconvex tablets, 10.6 x 4.4 mm and are available in blister packs of 2 tablets.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Apofri AB<\/p>\n\n\n\n<p>Box 120<\/p>\n\n\n\n<p>182 12 Danderyd<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Evolan Pharma AB<\/p>\n\n\n\n<p>Svardv\u00e4gen 19<\/p>\n\n\n\n<p>182 33 Danderyd<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sumatriptan Apofri belongs to a group of medicines called triptans, which are used to treat migraine headaches.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[13065,24862,24863,24864,13070,13068,13066,24866,24865,13067],"class_list":["post-23900","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-sumatriptan","tag-sumatriptan-apofree","tag-sumatriptan-apofree-side-effects","tag-sumatriptan-apofree-tablet","tag-sumatriptan-side-effects","tag-sumatriptan-tablet","tag-what-is-sumatriptan","tag-what-is-sumatriptan-apofree","tag-what-sumatriptan-apofree-is-used-for","tag-what-sumatriptan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23900"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23900\/revisions"}],"predecessor-version":[{"id":23926,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23900\/revisions\/23926"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}