{"id":23783,"date":"2022-08-06T08:26:40","date_gmt":"2022-08-06T08:26:40","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23783"},"modified":"2022-08-10T06:50:03","modified_gmt":"2022-08-10T06:50:03","slug":"strefen","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/strefen\/","title":{"rendered":"Strefen – Flurbiprofen uses, dose and side effects"},"content":{"rendered":"\n

8.75 mg lozenges
flurbiprofen 8.75 mg<\/a><\/p>\n\n\n\n

What Strefen lozenges are and what they are used for<\/h2>\n\n\n\n

Strefen lozenges contain flurbiprofen.\u00a0Flurbiprofen belongs to a group of pain-relieving drugs called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), which have analgesic, antipyretic and anti-inflammatory properties.\u00a0These drugs work by changing the body’s response to pain, swelling, and fever.<\/p>\n\n\n\n

Strefen lozenges are used for short-term symptom relief in sore throats, such as sore, painful, and swollen throats and difficulty swallowing in adults and children over 12 years of age.<\/p>\n\n\n\n

The flurbiprofen found in Strefen may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask a doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.
<\/p>\n\n\n\n

What you need to know before taking Strefen lozenges<\/h2>\n\n\n\n

Do not take these lozenges if you:<\/h2>\n\n\n\n

\u2022 are allergic (hypersensitive) to flurbiprofen or any of the other ingredients in Strefen (listed in section 6).<\/p>\n\n\n\n

\u2022 ever had\u00a0asthma, unexpected wheezing, shortness of breath, runny nose, facial swelling, or an itchy rash (\u00a0hives\u00a0) after taking\u00a0acetylsalicylic acid<\/a>\u00a0or any other NSAID preparation.<\/p>\n\n\n\n

\u2022 have or have ever had two or more episodes of\u00a0stomach ulcers, ulcers in the intestines, or bleeding in the gastrointestinal tract<\/p>\n\n\n\n

\u2022 have had bleeding or holes in the stomach or intestines, severe\u00a0colitis\u00a0(inflammation of the colon), or blood disorders when you have previously taken an\u00a0NSAID\u00a0preparation.<\/p>\n\n\n\n

\u2022 taking high\u00a0doses of\u00a0acetylsalicylic\u00a0acid\u00a0or other\u00a0NSAID\u00a0preparations (such as celecoxib,\u00a0ibuprofen, diclofenac sodium, etc.).<\/p>\n\n\n\n

\u2022 during the last three months of pregnancy.<\/p>\n\n\n\n

\u2022 have or have ever had severe heart, kidney, or liver disease.<\/p>\n\n\n\n

\u2022 is under 12 years of age.<\/a><\/p>\n\n\n\n

Warnings and precautions<\/h2>\n\n\n\n

Talk to your doctor or pharmacist before taking Strefen lozenges if you:<\/p>\n\n\n\n

\u2022 have ever had\u00a0asthma\u00a0or suffered from\u00a0allergies<\/p>\n\n\n\n

\u2022 have tonsillitis (strep throat) or think you may have a bacterial throat infection (as you may need antibiotics )<\/p>\n\n\n\n

\u2022 have heart, kidney, or liver problems<\/p>\n\n\n\n

\u2022 have had a stroke<\/p>\n\n\n\n

\u2022 have had any history of bowel disease (\u00a0ulcerative colitis,\u00a0Crohn’s disease\u00a0)<\/p>\n\n\n\n

\u2022 have a chronic ( autoimmune ) disease where the body’s immune system attacks its own body, such as systemic lupus erythematosus and mixed connective tissue disease.<\/p>\n\n\n\n

\u2022 are older, as the likelihood of you developing the side effects listed in this leaflet increases<\/p>\n\n\n\n

\u2022 are you in the first 6 months of pregnancy or are breastfeeding<\/p>\n\n\n\n

\u2022 cannot tolerate certain sugars
<\/a><\/p>\n\n\n\n

While using Strefen lozenges<\/h2>\n\n\n\n

\u2022 At the first sign of a skin reaction (rash, scaly skin, blisters) or other signs of\u00a0an allergic reaction, stop taking the lozenge and contact a doctor immediately.<\/p>\n\n\n\n

\u2022 Report any unusual symptoms (especially bleeding) to a doctor.<\/p>\n\n\n\n

\u2022 If you do not improve, get worse or if new symptoms appear, contact a doctor.<\/p>\n\n\n\n

\u2022 Medicines such as Strefen lozenges may be associated with a slightly increased risk of suffering a heart attack (\u00a0myocardial infarction\u00a0) or\u00a0stroke.\u00a0All risks increase with higher\u00a0doses\u00a0and long-term treatment.\u00a0Do not exceed the recommended\u00a0dose\u00a0or duration of treatment (3 days).<\/p>\n\n\n\n

Children<\/strong><\/p>\n\n\n\n

Children should not use the medicine under 12 years of age.<\/p>\n\n\n\n

Special warnings<\/strong><\/p>\n\n\n\n

If you have heart problems, have had a\u00a0stroke,\u00a0or think you may be at risk of these conditions (eg if you have high\u00a0blood pressure,\u00a0diabetes,\u00a0high\u00a0cholesterol,\u00a0or smoke) you should discuss the treatment with your doctor or pharmacist.<\/p>\n\n\n\n

Other medicines and Strefen lozenges<\/strong><\/p>\n\n\n\n

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, even those without a prescription.\u00a0In particular, tell them if you are taking:<\/p>\n\n\n\n

\u2022 low-dose aspirin (up to 75 mg a day)<\/p>\n\n\n\n

\u2022 medicines for high blood pressure or heart failure (antihypertensive medicines, cardiac glycosides)<\/p>\n\n\n\n

\u2022 diuretics (\u00a0diuretics, including potassium-sparing drugs)<\/p>\n\n\n\n

\u2022 medicines that thin the blood (\u00a0anticoagulants, platelet inhibitors)<\/p>\n\n\n\n

\u2022 medicines for gout (probenecid, sulfinpyrazone)<\/p>\n\n\n\n

\u2022 other\u00a0NSAID\u00a0preparations or\u00a0steroids\u00a0(such as celecoxib,\u00a0ibuprofen, diclofenac sodium, or\u00a0prednisolone\u00a0)<\/p>\n\n\n\n

\u2022 mifepristone (a medicine used to terminate a pregnancy)<\/p>\n\n\n\n

\u2022 quinolone antibiotics (such as ciprofloxacin )<\/p>\n\n\n\n

\u2022 ciclosporin or tacrolimus (to suppress the immune system).<\/p>\n\n\n\n

\u2022 phenytoin (to treat epilepsy )<\/p>\n\n\n\n

\u2022 methotrexate (to treat autoimmune diseases or cancer)<\/p>\n\n\n\n

\u2022 lithium or SSRI preparations (for depression)<\/p>\n\n\n\n

\u2022 oral diabetes medicines (to treat diabetes )<\/p>\n\n\n\n

\u2022 zidovudine (to treat HIV ).<\/a><\/p>\n\n\n\n

Strefen lozenges with food and drink<\/h2>\n\n\n\n

Alcohol should be avoided during treatment with Strefen lozenges because it increases the risk of bleeding in the gastrointestinal tract.<\/a><\/p>\n\n\n\n

Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n

Pregnant women should not use Strefen during the last three months of pregnancy.<\/strong><\/p>\n\n\n\n

If you are in the first 6 months of pregnancy or breastfeeding, talk to your doctor before taking these lozenges.<\/p>\n\n\n\n

Ingestion of Strefen should be avoided by women planning a pregnancy or who are pregnant.<\/p>\n\n\n\n

Strefen lozenges belong to a group of drugs ( NSAIDs ) that can make it harder to get pregnant.<\/p>\n\n\n\n

This effect ceases when the treatment is stopped.
<\/a><\/p>\n\n\n\n

Driving ability and use of machinery<\/h2>\n\n\n\n

No studies on the effects on the ability to drive or use machines have been performed. Dizziness and visual disturbances are, however, possible side effects after taking NSAIDs. If you experience these symptoms, do not drive or use machines.<\/p>\n\n\n\n

You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

Strefen lozenges contain glucose and sucrose<\/h2>\n\n\n\n

Strefen lozenges contain 1.069 g of\u00a0glucose\u00a0and 1.407 g of sucrose per lozenge.\u00a0This should be taken into account in patients with\u00a0diabetes mellitus.<\/p>\n\n\n\n

If you have an intolerance to certain sugars, you should consult your doctor before taking these lozenges.<\/p>\n\n\n\n

This medicine contains only very low levels of gluten (from wheat starch) and is considered “gluten-free”. It is very unlikely that it will cause problems if you have gluten intolerance ( celiac disease ) 1 lozenge contains no more than 21.38 micrograms of gluten.<\/p>\n\n\n\n

If you are allergic to wheat (a disease other than gluten intolerance) you should not use this medicine.<\/p>\n\n\n\n

This medicine contains fragrances with citral, citronellol, d-limonene, farnesol, geraniol, and linalool.<\/p>\n\n\n\n

Citral, citronellol, d-limonene, farnesol, geraniol, and linalool can cause allergic reactions.<\/p>\n\n\n\n

Sulfur dioxide (E220) can in rare cases cause serious hypersensitivity reactions and spasms in the trachea.<\/p>\n\n\n\n

Butylhydroxyanisole (E320) can cause local skin reactions (e.g. contact dermatitis) or be irritating to the eyes and mucous membranes

<\/p>\n\n\n\n

How to take Strefen lozenges<\/h2>\n\n\n\n

Always use this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

The recommended<\/strong>\u00a0dose\u00a0is for Adults and children from the age of 12:<\/strong><\/p>\n\n\n\n

\u2022 Take a lozenge in your mouth and let it dissolve slowly.<\/p>\n\n\n\n

\u2022 Keep moving the lozenge around in your mouth while it dissolves.<\/p>\n\n\n\n

\u2022 The lozenges should start working within 30 minutes.<\/p>\n\n\n\n

\u2022 Then take a lozenge every 3-6 hours, if needed.<\/p>\n\n\n\n

\u2022 Do not take more than 5 lozenges per day.<\/p>\n\n\n\n

Do not give Strefen lozenges to children under 12 years of age.<\/strong><\/p>\n\n\n\n

These lozenges are intended for short-term use only.<\/strong><\/p>\n\n\n\n

You should take as few lozenges as you need for the shortest time necessary to relieve the symptoms.<\/p>\n\n\n\n

If irritation occurs in the mouth, treatment with flurbiprofen should be discontinued.<\/p>\n\n\n\n

Do not take Strefen lozenges for more than 3 days<\/strong> unless your doctor has recommended it. If you do not improve or if you get worse, or if new symptoms appear, talk to a doctor or pharmacist.
<\/a><\/p>\n\n\n\n

If you have taken too many Strefen lozenges<\/h2>\n\n\n\n

If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n

The symptoms of overdose can be nausea or vomiting, stomach pain, or, more rarely, diarrhea.\u00a0Ringing in the ears, headache, and bleeding in the gastrointestinal tract are also possible symptoms.<\/p>\n\n\n\n

If you have any further questions about this medicine, ask your doctor or pharmacist.
<\/a><\/p>\n\n\n\n

If you forget to take Strefen lozenges<\/h2>\n\n\n\n

Do not take a double dose to make up for a missed tablet.<\/a><\/p>\n\n\n\n

Possible side effects<\/h2>\n\n\n\n

Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n

STOP TAKING this medicine and call your doctor immediately if you develop:<\/strong><\/p>\n\n\n\n

\u2022\u00a0signs of allergic reactions<\/strong>\u00a0such as\u00a0asthma, unexpected wheezing, shortness of breath,\u00a0itching, runny nose, or skin rash.<\/p>\n\n\n\n

\u2022 swelling of the face, tongue, or throat leading to breathing difficulties, palpitations, and a drop in blood pressure leading to\u00a0shock\u00a0(These may occur when the medicine is first used).<\/p>\n\n\n\n

\u2022 serious skin reactions such as scaly skin, blisters, or peeling skin.<\/p>\n\n\n\n

Talk to your doctor or pharmacist if you notice any of the following other side effects or any side effects not mentioned:<\/strong><\/p>\n\n\n\n

Common <\/strong>(affects 1 in 10 users)<\/em> :<\/p>\n\n\n\n

\u2022 headache, dizziness<\/p>\n\n\n\n

\u2022 throat irritation<\/p>\n\n\n\n

\u2022 mouth ulcers or pain in the mouth<\/p>\n\n\n\n

\u2022 sore throat<\/p>\n\n\n\n

\u2022 discomfort or abnormal sensation in the mouth (warming sensation, burning sensation, tingling sensation, etc.)<\/p>\n\n\n\n

\u2022 nausea, diarrhea<\/p>\n\n\n\n

\u2022 tingling and itching sensation in the skin<\/p>\n\n\n\n

Uncommon <\/strong>(affects 1 in 100 users)<\/em><\/p>\n\n\n\n

\u2022 drowsiness<\/p>\n\n\n\n

\u2022 blisters in the mouth or throat, numbness in the throat<\/p>\n\n\n\n

\u2022 swollen abdomen, abdominal pain, gas, constipation, indigestion, vomiting<\/p>\n\n\n\n

\u2022 dry mouth<\/p>\n\n\n\n

\u2022 burning sensation in the mouth, changes in taste<\/p>\n\n\n\n

\u2022 skin rash, itchy skin<\/p>\n\n\n\n

\u2022 fever, pain<\/p>\n\n\n\n

\u2022 sleepiness or difficulty sleeping<\/p>\n\n\n\n

\u2022 worsened\u00a0asthma, wheezing, shortness of breath<\/p>\n\n\n\n

\u2022 reduced feeling in the throat<\/p>\n\n\n\n

Rare <\/strong>(occurs in 1 in 1,000 users)<\/em><\/p>\n\n\n\n

\u2022 acute allergic reaction<\/p>\n\n\n\n

Frequency not known<\/strong> ( cannot be calculated from available data)<\/em><\/p>\n\n\n\n

\u2022\u00a0anemia,\u00a0thrombocytopenia\u00a0(low number of\u00a0blood platelets\u00a0which can cause bruising and bleeding)<\/p>\n\n\n\n

\u2022 swelling (\u00a0edema\u00a0), high\u00a0blood pressure,\u00a0heart failure, heart attack.<\/p>\n\n\n\n

\u2022 serious skin reactions, for example, bullous reactions, including\u00a0Stevens-Johnson syndrome,\u00a0Lyell’s syndrome,\u00a0and\u00a0toxic epidermal necrolysis.<\/p>\n\n\n\n

\u2022\u00a0hepatitis\u00a0(inflammation of the liver).<\/p>\n\n\n\n

How Strefen lozenges should be stored<\/h2>\n\n\n\n

Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n

Use before the expiry date stated on the packaging after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n

Store in the original packaging.<\/p>\n\n\n\n

Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n

Contents of the packaging and other information<\/h2>\n\n\n\n

Contents declaration<\/h2>\n\n\n\n