{"id":23478,"date":"2022-07-30T07:26:51","date_gmt":"2022-07-30T07:26:51","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23478"},"modified":"2022-08-02T06:58:28","modified_gmt":"2022-08-02T06:58:28","slug":"spiolto-respimat","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/spiolto-respimat\/","title":{"rendered":"Spiolto Respimat &#8211; Tiotropium\/olodaterol uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 micrograms\/2.5 micrograms per puff&nbsp;inhalation liquid, solution<br>tiotropium\/olodaterol<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Spiolto Respimat is and what it is used for<\/h2>\n\n\n\n<p><strong>What Spiolto Respimat is<\/strong><\/p>\n\n\n\n<p>Spiolto Respimat contains the two active substances <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiogiva\/\">tiotropium<\/a> and olodaterol.&nbsp;These belong to a group of medicines called long-acting bronchodilators.&nbsp;Tiotropium belongs to the subgroup of anticholinergics (smooth muscle relaxants).&nbsp;Olodaterol belongs to the subgroup of long-acting beta-2&nbsp;agonists&nbsp;(agents that stimulate&nbsp;beta-2 receptors&nbsp;).<\/p>\n\n\n\n<p><strong>What Spiolto Respimat is used for<\/strong><\/p>\n\n\n\n<p>Spiolto Respimat helps adult patients with chronic&nbsp;obstructive pulmonary disease&nbsp;(COPD) to breathe easier.&nbsp;COPD is a long-term lung disease that causes shortness of breath and coughing.&nbsp;The diagnosis of COPD is also associated with long-term&nbsp;bronchial catarrh&nbsp;(&nbsp;chronic&nbsp;bronchitis&nbsp;) and enlarged lung sacs (&nbsp;emphysema&nbsp;).<\/p>\n\n\n\n<p>Spiolto Respimat helps open your airways and makes it easier to get air in and out of the lungs.&nbsp;Regular use of Spiolto Respimat can also help when you have ongoing shortness of breath due to your illness, and help reduce the impact of the illness on your daily life.&nbsp;Because COPD is a long-term disease, you should take Spiolto Respimat every day, not just when you have breathing problems or other symptoms of COPD.<\/p>\n\n\n\n<p>Tiotropium and olodaterol contained in Spiolto Respimat may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Spiolto Respimat<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Spiolto Respimat<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to tiotropium or olodaterol or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are allergic to atropine or similar substances, e.g.\u00a0ipratropium or tiotropium.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p><strong>Talk to your doctor or pharmacist before using Spiolto Respimat<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have\u00a0asthma\u00a0(you should not use Spiolto Respimat to treat\u00a0asthma\u00a0)<\/li><li>if you have heart problems<\/li><li>if you have high\u00a0blood pressure<\/li><li>if you have\u00a0epilepsy<\/li><li>if you have a specific thyroid problem called\u00a0thyrotoxicosis<\/li><li>if you have an abnormal enlargement of an\u00a0artery, called an\u00a0aneurysm<\/li><li>if you have\u00a0diabetes<\/li><li>if you have severe liver disease<\/li><li>if you have kidney disease<\/li><li>in the event of a planned operation<\/li><li>if you have an eye\u00a0problem with narrow-angle glaucoma<\/li><li>if you have problems with the prostate or have difficulty emptying the bladder<\/li><\/ul>\n\n\n\n<p><strong>During treatment with Spiolto Respimat<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Stop using the medicine and contact your doctor immediately<\/strong>\u00a0if you feel chest pressure, cough, wheezing, or shortness of breath immediately after using the medicine.\u00a0This may be a sign of a condition called\u00a0bronchospasm\u00a0(see section 4).<\/li><li>If breathing becomes difficult or you experience a skin rash, swelling, or\u00a0itching\u00a0immediately after\u00a0inhalation, stop using Spiolto Respimat and contact a doctor immediately (see section 4).<\/li><li>If you experience any\u00a0side effects\u00a0affecting the heart (increased\u00a0heart rate, increased\u00a0blood pressure,\u00a0and\/or increase in symptoms such as chest pain), contact your doctor immediately (see section 4).<\/li><li>If you experience muscle twitching, muscle weakness, or abnormal heart rhythm, consult your doctor as these symptoms may be linked to low potassium levels in the blood (see section 4).<\/li><\/ul>\n\n\n\n<p>When taking Spiolto Respimat, be careful not to get the inhalation liquid in your eyes.\u00a0This can cause pain or discomfort in the eyes, blurred vision, and visual phenomena associated with red eyes (ie\u00a0narrow-angle glaucoma\u00a0).\u00a0Symptoms from the eyes may be accompanied by headache, nausea, or vomiting.\u00a0Clean the eyes with lukewarm water and stop using Spiolto Respimat and immediately contact your doctor for advice.<\/p>\n\n\n\n<p>Spiolto Respimat should be used for the maintenance treatment of\u00a0chronic obstructive pulmonary disease.\u00a0<strong>It should not be used to treat sudden attacks of shortness of breath or wheezing.<\/strong><\/p>\n\n\n\n<p>Do not use Spiolto Respimat together with certain medicines that contain long-acting beta-agonists, such as\u00a0salmeterol\u00a0or formoterol.<\/p>\n\n\n\n<p>If you regularly take medicines called short-acting beta-agonists, such as\u00a0salbutamol, continue taking them only to relieve acute symptoms such as shortness of breath.<\/p>\n\n\n\n<p>Dry mouth, observed during treatment with anticholinergic drugs, can lead to cavities in the teeth during long-term treatment.\u00a0Therefore, be careful with oral hygiene.<\/p>\n\n\n\n<p>Do not use Spiolto Respimat more often than once a day.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Spiolto Respimat\u00a0<strong>should not<\/strong>\u00a0be given to\u00a0<strong>children or adolescents (under 18 years)<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Spiolto Respimat<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines.<\/p>\n\n\n\n<p>In particular, you should tell your doctor if you use:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain medicines similar to Spiolto Respimat (contain similar active substances, such as anticholinergic medicines or beta-adrenergic agents).\u00a0It may increase your risk of\u00a0side effects.<\/li><li>medicines called beta-blockers are used for high\u00a0blood pressure\u00a0or other heart problems (such as propranolol), or the eye disease\u00a0glaucoma\u00a0(such as\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/\">timolol<\/a>\u00a0).\u00a0This may result in a reduced effect of Spiolto Respimat.<\/li><li>medicines that lower the potassium level in the blood.\u00a0These include:<ul><li>cortisone\u00a0(so-called\u00a0steroids, for example,\u00a0prednisolone\u00a0),<\/li><li>diuretics\u00a0(water tablets),<\/li><li>and medicines for breathing problems such as theophylline.<br>If you use these medicines together with Spiolto Respimat, you may experience symptoms such as muscle twitching, muscle weakness, or abnormal heart rhythm.<\/li><\/ul><\/li><li>medicines called\u00a0tricyclic antidepressants\u00a0or\u00a0MAO inhibitors\u00a0(such as\u00a0selegiline\u00a0or moclobemide), which are used to treat neurological or psychiatric disorders such as\u00a0Parkinson&#8217;s disease\u00a0or depression.\u00a0Simultaneous use of these medicines increases the risk of you getting\u00a0side effects\u00a0that affect your heart.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.\u00a0You should not use this medicine unless your doctor has specifically recommended it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>No studies have been carried out regarding the effect on the ability to drive vehicles and use machines.&nbsp;If you feel dizzy or have blurred vision while taking Spiolto Respimat, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Spiolto Respimat contains benzalkonium chloride<\/h2>\n\n\n\n<p>This medicine contains 0.0011 mg benzalkonium chloride per puff.\u00a0Benzalkonium chloride can cause wheezing and difficulty breathing (bronchial spasm), especially if you have\u00a0asthma.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Spiolto Respimat<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Spiolto Respimat is intended for\u00a0inhalation\u00a0only.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is:<\/p>\n\n\n\n<p>Spiolto Respimat is effective for 24 hours and therefore only needs to be used\u00a0<strong>ONCE PER DAY<\/strong>, if possible at the same time.\u00a0For each use, take\u00a0TWO PUFFS.<\/p>\n\n\n\n<p>Because COPD is a long-term disease, Spiolto Respimat should be used every day and not only for breathing problems.\u00a0Do not use more than the recommended\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>There is no relevant use for Spiolto Respimat in children (under 18 years).<\/p>\n\n\n\n<p>Make sure you know how to use Spiolto Respimat&nbsp;inhaler&nbsp;correctly.&nbsp;Instructions for use for the Spiolto Respimat&nbsp;inhaler&nbsp;can be found on the back of this leaflet.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Spiolto Respimat<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>You may be at higher risk of\u00a0side effects\u00a0such as\u00a0dry mouth, constipation, difficulty emptying the bladder, blurred vision, chest pain, high or low\u00a0blood pressure, fast or irregular heartbeats or palpitations, dizziness, nervousness, difficulty sleeping, anxiety, headache, tremors, muscle cramps, nausea, tiredness, feeling unwell, low levels of\u00a0potassium\u00a0in the blood (which can cause symptoms such as muscle twitching, muscle weakness or abnormal heart rhythm), high blood sugar, or too acidic blood (which can cause symptoms such as nausea, vomiting, weakness, muscle cramps, and faster breathing ).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Spiolto Respimat<\/h2>\n\n\n\n<p>If you forget to inhale a\u00a0dose, inhale a\u00a0dose\u00a0at the usual time the next day.<\/p>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Spiolto Respimat<\/h2>\n\n\n\n<p>Before you stop using Spiolto Respimat, talk to your doctor or pharmacist.&nbsp;If you stop using Spiolto Respimat, the symptoms of COPD may worsen.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>If any of the following occur<strong>, stop using this medicine<\/strong>\u00a0and contact your doctor immediately.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Immediate\u00a0hypersensitivity reactions\u00a0to Spiolto Respimat are rare (may affect up to 1 in 1,000 users).\u00a0These reactions may occur as a single reaction or as part of a severe\u00a0allergic reaction\u00a0(\u00a0anaphylactic reaction\u00a0) after the administration of Spiolto Respimat.\u00a0These include skin rash,\u00a0hives\u00a0(\u00a0urticaria\u00a0), swelling of the mouth and face, sudden difficulty in breathing (\u00a0angioneurotic edema), or other\u00a0hypersensitivity reactions\u00a0(such as a sudden drop in blood pressure or feeling faint).<\/li><li>As with other inhaled medicines, chest tightness, coughing, wheezing or shortness of breath may occur immediately after\u00a0inhalation\u00a0(paradoxical\u00a0bronchospasm\u00a0).\u00a0Based on the data available, it is not possible to assess how common it is.<\/li><li>Visual phenomena such as rings of light or colored images associated with red eyes (\u00a0glaucoma\u00a0) occur in an unknown number of users.<\/li><li>Blockage in the bowels or failure to have bowel movements (intestinal obstruction including bowel obstruction) occurs in an unknown number of users.<\/li><\/ul>\n\n\n\n<p>Other possible side effects:<\/p>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>faster heartbeat (&nbsp;tachycardia&nbsp;)<\/li><li>dizziness<\/li><li>headache<\/li><li>cough<\/li><li>hoarseness (&nbsp;dysphonia&nbsp;)<\/li><li>dry mouth<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>irregular heartbeat (\u00a0atrial fibrillation\u00a0)<\/li><li>fast heartbeat (\u00a0supraventricular\u00a0tachycardia\u00a0)<\/li><li>a heartbeat that can be felt (palpitations)<\/li><li>high\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0)<\/li><li>difficulty emptying the bladder (\u00a0urinary retention\u00a0)<\/li><li>urinary tract infections<\/li><li>pain when emptying the bladder (\u00a0dysuria\u00a0)<\/li><li>sore throat (\u00a0pharyngitis\u00a0)<\/li><li>inflammation\u00a0of the larynx (\u00a0laryngitis\u00a0)<\/li><li>inflamed gums (\u00a0gingivitis\u00a0)<\/li><li>inflammation\u00a0of the oral mucosa (stomatitis)<\/li><li>fungal infection of the mouth and throat (\u00a0oropharyngeal\u00a0candidiasis)<\/li><li>nosebleeds (\u00a0epistaxis\u00a0)<\/li><li>insomnia\u00a0_\u00a0_<\/li><li>blurred vision<\/li><li>chest pressure, associated with coughing, wheezing or wheezing or shortness of breath immediately after\u00a0inhalation\u00a0(\u00a0bronchospasm\u00a0)<\/li><li>constipation<\/li><li>nausea<\/li><li>itching\u00a0(\u00a0pruritus\u00a0)<\/li><li>joint pain (\u00a0arthralgia\u00a0)<\/li><li>swollen joints<\/li><li>back pain<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased measured pressure in the eye<\/li><li>Runny nose<\/li><li>sinusitis (&nbsp;sinusitis&nbsp;)<\/li><li>difficulty swallowing (&nbsp;dysphagia&nbsp;)<\/li><li>inflammation&nbsp;of the tongue (&nbsp;glossitis&nbsp;)<\/li><li>heartburn (&nbsp;gastroesophageal&nbsp;reflux)<\/li><li>holes in the teeth (&nbsp;caries&nbsp;)<\/li><li>infection&nbsp;or wounds in the skin<\/li><li>dry skin<\/li><li>loss of body fluid (&nbsp;dehydration&nbsp;)<\/li><\/ul>\n\n\n\n<p>You may also experience\u00a0side effects\u00a0known from treating breathing problems with medicines similar to Spiolto Respimat (beta agonists).\u00a0These can be irregular heartbeats, chest pain, low\u00a0blood pressure, tremors, nervousness, muscle cramps, tiredness, feeling unwell, and low levels of\u00a0potassium\u00a0in the blood (which can cause symptoms such as muscle twitching, muscle weakness, or abnormal heart rhythm), high blood sugar, or too acidic blood (which can cause symptoms such as nausea, vomiting, weakness, muscle cramps and faster breathing).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Spiolto Respimat<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and the inhaler label after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not freeze.<\/p>\n\n\n\n<p>Shelf life after opening:<\/p>\n\n\n\n<p>Replace the medication container no later than three months after insertion.<\/p>\n\n\n\n<p>Do not use the same Respimat reusable&nbsp;inhaler&nbsp;for more than one year.<\/p>\n\n\n\n<p>Recommended use: up to 6 medicine containers per\u00a0inhaler.<\/p>\n\n\n\n<p>Note: Respimat reusable&nbsp;inhaler&nbsp;has been tested with 540 puffs (corresponding to 9 containers) with maintained function.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substances are tiotropium and olodaterol.\u00a0The delivered\u00a0dose\u00a0is 2.5 micrograms of tiotropium (as bromide monohydrate) and 2.5 micrograms olodaterol (as hydrochloride) per puff.<\/p>\n\n\n\n<p>The delivered&nbsp;dose&nbsp;is the&nbsp;dose&nbsp;available to the patient after passing through the nozzle.<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>Benzalkonium chloride, disodium edetate, purified water, and\u00a0hydrochloric acid\u00a0for\u00a0pH\u00a0adjustment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Spiolto Respimat consists of a medicine container with inhalation solution and a Respimat\u00a0inhaler.\u00a0The container must be inserted into the inhaler before first use.<\/p>\n\n\n\n<p>1-pack: 1 Respimat reusable&nbsp;inhaler&nbsp;and 1 medication container, containing 60 puffs (30 medication doses)<\/p>\n\n\n\n<p>3-pack: 1 Respimat reusable&nbsp;inhaler&nbsp;and 3 medication containers, each containing 60 puffs (30 medication doses)<\/p>\n\n\n\n<p>1-pack refill: 1 medication container, containing 60 puffs (30 medication doses)<\/p>\n\n\n\n<p>3-pack refill: 3 medication containers, containing 60 puffs (30 medication doses) each<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>The marketing authorization holder<\/strong>&nbsp;for Spiolto Respimat is:<\/p>\n\n\n\n<p>Boehringer Ingelheim International GmbH<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturers<\/strong>&nbsp;of Spiolto Respimat are:<\/p>\n\n\n\n<p>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KG<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><em>alternatively<\/em><\/p>\n\n\n\n<p>Boehringer Ingelheim Espa\u00f1a, SA<\/p>\n\n\n\n<p>c\/ Prat de la Riba, 50<\/p>\n\n\n\n<p>08174 Sant Cugat del Vall\u00e8s (Barcelona)<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p><em>alternatively<\/em><\/p>\n\n\n\n<p>Boehringer Ingelheim France<\/p>\n\n\n\n<p>100-104 Avenue de France<\/p>\n\n\n\n<p>75013 Paris<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><em>Information provided by<\/em>&nbsp;:<\/p>\n\n\n\n<p>Boehringer Ingelheim AB, Box 92008, 120 06 Stockholm.&nbsp;Phone: 08 \u2013 721 21 00<\/p>\n\n\n\n<p>Email: info.sto@boehringer-ingelheim.com<\/p>\n\n\n\n<p><strong>This medicine is approved in the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p><strong>Austria, Liechtenstein:<\/strong>&nbsp;Spiolto Respimat 2.5 Microgram\/2.5 Microgram \u2013 L\u00f6sung zur&nbsp;Inhalation<\/p>\n\n\n\n<p><strong>Belgium, Luxembourg:<\/strong>&nbsp;Spiolto Respimat 2.5 microgrammes\/2.5 microgrammes\/inhalation, solution \u00e0 inhaler<\/p>\n\n\n\n<p><strong>Bulgaria:<\/strong>&nbsp;Spiolto Respimat \u0421\u043f\u0438\u043e\u043b\u0442\u043e \u0420\u0435\u0441\u043f\u0438\u043c\u0430\u0442<\/p>\n\n\n\n<p><strong>Cyprus, Greece:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Croatia<\/strong>\u00a0Spiolto Respimat 2.5 micrograms\/ 2.5 micrograms, solution inhalation<\/p>\n\n\n\n<p><strong>Czech Republic:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Denmark:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Estonia:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Finland:<\/strong>&nbsp;&nbsp; Inspiolto Respimat 2.5 microg\/2.5 microg inhalaationeste, liuos<\/p>\n\n\n\n<p><strong>France:<\/strong>&nbsp;Spiolto Respimat 2.5 microgrammes\/2.5 microgrammes\/dose, solution \u00e0 inhaler<\/p>\n\n\n\n<p><strong>Germany:<\/strong>&nbsp;Spiolto Respimat 2.5 Microgram\/2.5 Microgram pro Hub, L\u00f6sung<br>zur&nbsp;Inhalation<\/p>\n\n\n\n<p><strong>Hungary:<\/strong>&nbsp;Spiolto Respimat 2.5 micrograms\/2.5 micrograms inhal\u00e1ci\u00f3s oldat<\/p>\n\n\n\n<p><strong>Iceland:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Ireland, Malta,&nbsp;<\/strong><strong>UK:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Italy:<\/strong>&nbsp;Spiolto Respimat 2.5 microgrammi\/2.5 microgrammi, soluzione<br>per inalazione<\/p>\n\n\n\n<p><strong>Latvia:<\/strong>\u00a0Spiolto Respimat 2.5 micrograms\/2.5 micrograms inhalations \u0161kidums<\/p>\n\n\n\n<p><strong>Lithuania:<\/strong>&nbsp;Spiolto Respimat 2.5 microgram\/2.5 microgram\/i\u0161pur\u0161kime<br>\u012fkvepiamasis tirpalas<\/p>\n\n\n\n<p><strong>The Netherlands:<\/strong>\u00a0Spiolto Respimat 2.5 microgram\/2.5 microgram, inhalation oplossing<\/p>\n\n\n\n<p><strong>Norway:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Poland:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Portugal:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Romania:<\/strong>&nbsp;Spiolto Respimat 2.5 micrograme\/2.5 micrograme soluzione de inhalat<\/p>\n\n\n\n<p><strong>Slovakia:<\/strong>&nbsp;Spiolto Respimat<\/p>\n\n\n\n<p><strong>Slovenia:<\/strong>&nbsp;Spiolto Respimat 2.5 micrograms\/2.5 micrograms<\/p>\n\n\n\n<p><strong>Spain:<\/strong>\u00a0Spiolto Respimat 2.5 microgramos\/2.5 microgramos soluci\u00f3n para inhalaci\u00f3n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2.5 micrograms\/2.5 micrograms per puff&nbsp;inhalation liquid, solutiontiotropium\/olodaterol What Spiolto Respimat is and what it is used for What Spiolto Respimat is Spiolto Respimat contains the two active substances tiotropium and olodaterol.&nbsp;These belong to a group of medicines called long-acting bronchodilators.&nbsp;Tiotropium belongs to the subgroup of anticholinergics (smooth muscle relaxants).&nbsp;Olodaterol belongs to the subgroup of long-acting [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24544,24550,24553,8517,24551,24554,24552,8520],"class_list":["post-23478","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-tiotropium","tag-spiolto-respimat","tag-spiolto-respimat-side-effects","tag-tiotropium","tag-what-is-spiolto-respimat","tag-what-is-tiotropiumtiotropium-side-effects","tag-what-spiolto-respimat-is-used-for","tag-what-tiotropium-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23478"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23478\/revisions"}],"predecessor-version":[{"id":23502,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23478\/revisions\/23502"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}