{"id":23470,"date":"2022-07-30T07:18:13","date_gmt":"2022-07-30T07:18:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23470"},"modified":"2022-08-02T06:58:44","modified_gmt":"2022-08-02T06:58:44","slug":"spectramox","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/spectramox\/","title":{"rendered":"Spectramox &#8211; Amoxicillin\/clavulanic acid uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg\/125 mg&nbsp;film-coated tablets<br>amoxicillin\/clavulanic acid<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Spektramox is and what it is used for<\/h2>\n\n\n\n<p>Spectramox is an\u00a0antibiotic\u00a0that works by killing bacteria that cause\u00a0infection.\u00a0It contains two different drugs called amoxicillin and\u00a0clavulanic acid.\u00a0Amoxicillin belongs to a group of medicines called &#8216;penicillins&#8217; which can sometimes stop working (become inactive).\u00a0The other active substance (\u00a0clavulanic acid\u00a0) prevents this from happening.<\/p>\n\n\n\n<p>Spectramox is used in adults and children to treat the following infections:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection&nbsp;in the middle ear and sinus infections<\/li><li>respiratory tract infections<\/li><li>urinary tract infections<\/li><li>skin and soft tissue infections including dental infections<\/li><li>bone and joint infections.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Spektramox<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Spektramox:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to amoxicillin,\u00a0clavulanic acid,\u00a0penicillin,\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have had a severe\u00a0allergic reaction\u00a0(\u00a0hypersensitivity reaction\u00a0) to any other\u00a0antibiotic.\u00a0This may include a rash or swelling of the face or neck.<\/li><li>if you have had liver problems or jaundice (yellowish skin) when you have taken an\u00a0antibiotic.<\/li><li><strong>Do not take Spektramox if any of the above applies to you.\u00a0<\/strong>If you are not sure, talk to your doctor or pharmacist before taking Spektramox.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking this medicine if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have glandular fever<\/li><li>being treated for liver or kidney problems<\/li><li>not peeing regularly.<\/li><\/ul>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking Spektramox.<\/p>\n\n\n\n<p>In some cases, your doctor can investigate the type of\u00a0bacteria\u00a0causing your\u00a0infection.\u00a0Depending on the results, you may receive a different strength of Spektramox or another medicine.<\/p>\n\n\n\n<p><strong>Conditions you must be aware of:<\/strong><\/p>\n\n\n\n<p>Spectramox can worsen certain existing conditions, or cause serious\u00a0side effects.\u00a0These include allergic reactions, convulsions, and\u00a0inflammation\u00a0of the colon. You need to be aware of certain symptoms when taking Spektramox to reduce the risk of possible problems.\u00a0See\u00a0<em>\u201cConditions you need to be aware of\u201d<\/em>\u00a0in\u00a0<strong>section 4.<\/strong><\/p>\n\n\n\n<p><strong>Blood and urine samples<\/strong><\/p>\n\n\n\n<p>If you are having blood tests (eg to check&nbsp;red blood cells&nbsp;or liver function tests) or urine tests (for&nbsp;glucose&nbsp;), tell the doctor or nurse that you are taking Spektramox.&nbsp;This is because Spektramox can affect the results of these types of samples.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Spektramox<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>If you take allopurinol (for&nbsp;gout&nbsp;) together with Spektramox, the risk of an allergic skin reaction may be greater.<\/p>\n\n\n\n<p>If you take probenecid (for&nbsp;gout&nbsp;), the doctor can change the&nbsp;dose&nbsp;of Spektramox.<\/p>\n\n\n\n<p>If you are taking blood-thinning medicines to prevent blood clots (eg&nbsp;warfarin&nbsp;) together with Spektramox, you may need to provide extra blood samples.<\/p>\n\n\n\n<p>Spectramox can affect how methotrexate (a medicine to treat cancer or rheumatic diseases) works.<\/p>\n\n\n\n<p>Spectramox can affect how mycophenolate mofetil (a medicine that prevents the rejection of transplanted organs) works.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Spektramox can have&nbsp;side effects&nbsp;and the symptoms can make you unfit to drive.&nbsp;Do not drive or use machines if you feel unwell.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Spectramox contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8220;sodium-free&#8221;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Spektramox<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Adults and children weighing 40 kg or more<\/strong><\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0is:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>1 tablet 3 times daily<\/li><\/ul>\n\n\n\n<p><strong>Children weighing less than 40 kg<\/strong><\/p>\n\n\n\n<p>Children who are 6 years of age or younger should preferably be treated with Spektramox\u00a0oral\u00a0suspension.<\/p>\n\n\n\n<p>Consult a doctor or pharmacist when giving Spektramox tablets to children weighing less than 40 kg.<\/p>\n\n\n\n<p><strong>Patients with kidney and liver problems<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The dose\u00a0may be changed if you have kidney problems.\u00a0Your doctor may choose a different strength or different medicine.<\/li><li>If you have liver problems, you may be given more frequent blood tests to check how your liver is working.<\/li><\/ul>\n\n\n\n<p><strong>How to take Spektramox<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the tablets whole with a glass of water at the beginning of a meal or just before.<\/li><li>Distribute the&nbsp;doses&nbsp;evenly throughout the day, at least 4 hours apart.&nbsp;Do not take 2&nbsp;doses&nbsp;within 1 hour.<\/li><li>Do not take Spektramox for more than 2 weeks.&nbsp;If you still feel unwell, see a doctor again.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Spektramox<\/h2>\n\n\n\n<p>If you have taken too much Spektramox, you may have symptoms such as an upset stomach (nausea, vomiting, or diarrhea) or convulsions.\u00a0Contact the doctor as soon as possible.\u00a0Take the box or bottle of medicine with you and show the doctor.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor, or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Spektramox<\/h2>\n\n\n\n<p>If you have forgotten a\u00a0dose, take it as soon as you remember.\u00a0You should not take the next\u00a0dose\u00a0too soon, but wait about 4 hours before taking it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Spektramox<\/h2>\n\n\n\n<p>Continue to take Spektramox until the treatment is finished, even if you feel better.\u00a0You need every\u00a0dose\u00a0to fight\u00a0infection.\u00a0If some bacteria survive, it can lead to\u00a0a recurrence of\u00a0the infection.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Conditions you must be aware of:<\/strong><\/p>\n\n\n\n<p><strong>Allergic reactions:<\/strong><\/p>\n\n\n\n<p>Has occurred in a very small number of people:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><li>inflammation\u00a0of blood vessels\u00a0<em>(\u00a0vasculitis\u00a0)<\/em>\u00a0which can be seen as red or purple, raised spots on the skin but can affect other parts of the body<\/li><li>fever, joint pain, swollen\u00a0glands\u00a0on the neck, in the armpits, or the groin<\/li><li>swelling, sometimes of the face or mouth\u00a0<em>(\u00a0angioedema\u00a0)<\/em>\u00a0leading to breathing difficulties<\/li><li>collapse.<\/li><li><strong>Contact a doctor immediately<\/strong>\u00a0if you experience any of these symptoms.\u00a0<strong>Stop taking Spectramox.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Inflammation&nbsp;of the colon<\/strong><\/p>\n\n\n\n<p>Has occurred in a very small number of people:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation\u00a0of the colon causes watery diarrhea, usually with blood and mucus, stomach pain, and\/or fever.<\/li><li><strong>Contact your doctor as soon as possible<\/strong>\u00a0for advice if you experience these symptoms.<\/li><\/ul>\n\n\n\n<p><strong>Serious skin reactions<\/strong><\/p>\n\n\n\n<p>It May affect up to 1 in 1,000 people:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin rash, which may blister and look like small targets (a dark dot in the center surrounded by a paler area, with a dark ring around the edge \u2013&nbsp;<em>erythema multiforme<\/em>&nbsp;)<\/li><\/ul>\n\n\n\n<p>Has occurred in a very small number of people:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a widespread rash with blisters and peeling skin, especially around the mouth, nose, eyes, and genitals (\u00a0Stevens-Johnson syndrome\u00a0), and a more severe form that causes extensive peeling of the skin (more than 30% of the body surface &#8211;\u00a0toxic epidermal necrolysis\u00a0)<\/li><li>an extensive red rash with small blisters where (\u00a0bullous exfoliative\u00a0dermatitis\u00a0)<\/li><li>a red, scaly rash with bumps under the skin and blisters (\u00a0exanthematous\u00a0pustulosis\u00a0).<\/li><li>flu-like symptoms\u00a0with rash, fever, swollen\u00a0glands,\u00a0and abnormal blood test results (including increased\u00a0white blood cell count\u00a0(\u00a0eosinophilia\u00a0) and liver enzymes) (drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS)).<\/li><li><strong>Contact a doctor immediately if you experience any of these symptoms.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These may affect more than 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>with diarrhea (in adults).<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These may affect up to 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>thrush (\u00a0<em>candida\u00a0<\/em>\u2013 a yeast infection in the vagina, mouth, or skin folds)<\/li><li>nausea,\u00a0especially when taking high\u00a0doses<\/li><li>if you suffer from this, take Spektramox before a meal<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><li>diarrhea (in children).<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These may affect up to 1 in 100 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin rash,&nbsp;itching<\/li><li>raised, itchy rash (hives)<\/li><li>indigestion<\/li><li>dizziness<\/li><li>headache.<\/li><\/ul>\n\n\n\n<p>Less common&nbsp;side effects&nbsp;that may show up in blood tests:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increase in certain substances&nbsp;<em>(&nbsp;<\/em><em>enzymes&nbsp;)<\/em>&nbsp;produced in the liver.<\/li><\/ul>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0ar<\/strong><\/p>\n\n\n\n<p>These may affect up to 1 in 1,000 people<\/p>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;that can show up in blood tests:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the low number of\u00a0blood cells\u00a0that are involved in the coagulation of the blood<\/li><li>low\u00a0white blood cell count.<\/li><\/ul>\n\n\n\n<p><strong>Other side effects that have been reported<\/strong><\/p>\n\n\n\n<p>These&nbsp;side effects&nbsp;have occurred in a very small number of people, but their exact incidence is unknown.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inflammation\u00a0of the liver (\u00a0<em>hepatitis<\/em>\u00a0)<\/li><li>inflammation\u00a0of the meninges and spinal cord (\u00a0<em>aseptic\u00a0meningitis<\/em>\u00a0)<\/li><li>jaundice is caused by increases in\u00a0bilirubin\u00a0in the blood (a substance produced in the liver) which can make the skin and whites of the eyes look yellow<\/li><li>inflammation\u00a0of the kidneys<\/li><li>it takes longer for the blood to clot<\/li><li>hyperactivity<\/li><li>seizures (in people taking high\u00a0doses\u00a0of Spektramox or who have kidney problems)<\/li><li>a black tongue that looks hairy<\/li><li>stains on the teeth (in children), usually go away with brushing.<\/li><\/ul>\n\n\n\n<p>Side effects&nbsp;that can show up in blood or urine tests:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe decrease in the number of&nbsp;white blood cells<\/li><li>low&nbsp;red blood cell count&nbsp;(&nbsp;<em>hemolytic anemia<\/em>&nbsp;)<\/li><li>crystals in the urine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Spektramox<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Tablets in a jar: Store in the original packaging.<\/p>\n\n\n\n<p>Tablets in blisters: Store at a maximum of 25\u00baC.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p><em>The active substances are:<\/em>&nbsp;amoxicillin and&nbsp;clavulanic acid<\/p>\n\n\n\n<p>1 tablet contains amoxicillin trihydrate corresponding to amoxicillin 500 mg and potassium clavulanate corresponding to&nbsp;clavulanic acid&nbsp;125 mg.<\/p>\n\n\n\n<p><em>Other ingredients are<\/em>\u00a0sodium starch glycolate,\u00a0colloidal\u00a0anhydrous silica, magnesium stearate, and microcrystalline cellulose.\u00a0Film coating: dye (titanium dioxide E 171), hypromellose, macrogol, dimethicone.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>White, oval, film-coated tablets, marked with score and AC on one side.<\/p>\n\n\n\n<p><em>Package size:<\/em><\/p>\n\n\n\n<p>20, 30, and 100 pcs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Viatris AB<\/p>\n\n\n\n<p>Box 23033<\/p>\n\n\n\n<p>104 35 Stockholm<\/p>\n\n\n\n<p>Telephone 08-630 19 00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Spectramox is an\u00a0antibiotic\u00a0that works by killing bacteria that cause\u00a0infection\u00a0.\u00a0It contains two different drugs called amoxicillin and\u00a0clavulanic acid\u00a0.\u00a0Amoxicillin belongs to a group of medicines called &#8216;penicillins&#8217; which can sometimes stop working (become inactive).\u00a0The other active substance (\u00a0clavulanic acid\u00a0) prevents this from happening.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[8787,24571,24565,24569,24568,24570,8788,8793,24566,24567],"class_list":["post-23470","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-amoxicillin","tag-clavulanic-acid-tabelt","tag-spectramox","tag-spectramox-side-effects","tag-spectramox-tablet","tag-what-clavulanic-acid-is-usd-for","tag-what-is-amoxicillin","tag-what-is-clavulanic-acid","tag-what-is-spectramox","tag-what-spectramox-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23470"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23470\/revisions"}],"predecessor-version":[{"id":23504,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23470\/revisions\/23504"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23470"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23470"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}