{"id":23465,"date":"2022-07-30T07:12:30","date_gmt":"2022-07-30T07:12:30","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23465"},"modified":"2022-08-02T06:59:20","modified_gmt":"2022-08-02T06:59:20","slug":"sparkal-and-sparkal-mite","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sparkal-and-sparkal-mite\/","title":{"rendered":"Sparkal and Sparkal Mite &#8211; Amiloride hydrochloride and\u00a0hydrochlorothiazide uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg\/50 mg and 2.5 mg\/25 mg&nbsp;tablets<br>amiloride hydrochloride and&nbsp;hydrochlorothiazide<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sparkal\/Sparkal Mite is and what it is used for<\/h2>\n\n\n\n<p>Sparkal\/Sparkal\u00a0Mite\u00a0is used for the treatment of high\u00a0blood pressure,\u00a0edema\u00a0(fluid accumulation in the\u00a0tissues\u00a0) due to\u00a0heart failure,\u00a0and cirrhosis with fluid in the abdominal cavity.<\/p>\n\n\n\n<p>The two active substances in Sparkal\/Sparkal\u00a0Mite\u00a0are\u00a0diuretic\u00a0and blood pressure lowering.\u00a0Amiloride hydrochloride is also\u00a0potassium-\u00a0and magnesium-sparing and counteracts the losses of\u00a0potassium\u00a0and\u00a0magnesium\u00a0that can be caused by\u00a0diuretics.<\/p>\n\n\n\n<p>Amiloride hydrochloride and\u00a0hydrochlorothiazide\u00a0found in Sparkal\/Sparkal\u00a0Mite\u00a0may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Sparkal\/Sparkal Mite:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to amiloride hydrochloride and\u00a0hydrochlorothiazide\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are hypersensitive to ingredients or chemically related agents, e.g.\u00a0certain other diuretics or sulfa drugs.<\/li><li>If you have severely impaired kidney or liver function.<\/li><li>If you have high levels of\u00a0potassium\u00a0in your blood.<\/li><li>If you use other potassium-sparing agents or potassium supplements.<\/li><li>If you have decreased or stopped passing urine.<\/li><li>If you have\u00a0gout.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Sparkal\/Sparkal Mite:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have reduced kidney or liver function.<\/li><li>if you are older, you may then be extra sensitive to disturbances in the salt balance in the blood<\/li><li>if you have\u00a0diabetes, this may be worsened by the treatment, and an adjustment of the\u00a0dose\u00a0of one of your diabetes medicines may be needed.<\/li><li>if you have high levels of\u00a0uric acid,\u00a0cholesterol,\u00a0or\u00a0triglycerides\u00a0(a type of\u00a0cholesterol\u00a0) in your blood.<\/li><li>if you have systemic lupus erythematosus (an\u00a0autoimmune\u00a0disease), this may be worsened by the treatment.<\/li><li>if you have had skin cancer or if you get an unexpected skin change during treatment.\u00a0Treatment with\u00a0hydrochlorothiazide, especially long-term use at high\u00a0doses, may increase the risk of certain types of skin and lip cancer (non-melanoma\u00a0skin cancer).\u00a0Protect your skin from exposure to sunlight and UV rays while using Sparkal\/Sparkal\u00a0Mite.<\/li><li>if you have previously had breathing or lung problems (including\u00a0inflammation\u00a0or fluid in the lungs) after taking\u00a0hydrochlorothiazide.\u00a0If you experience severe shortness of breath or severe breathing problems after taking Sparkal\/Sparkal\u00a0Mite, seek medical attention immediately.<\/li><\/ul>\n\n\n\n<p>If you experience impaired vision or eye pain, contact a doctor.\u00a0These may be symptoms of fluid accumulation in the eye (between the choroid and sclera) or an increase in pressure in the eye and may occur within hours to weeks of taking Sparkal\/Sparkal\u00a0Mite.\u00a0This can lead to permanent vision loss if left untreated.\u00a0If you have previously had a\u00a0penicillin\u00a0or sulfonamide allergy, you may be at a higher risk of developing this.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<p>The doctor needs to know if you are being treated with:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Potassium-sparing agents or potassium supplements.<\/li><li>Digitalis\u00a0and sotalol (heart medicine).<\/li><li>Cholestyramine and colestipol, are used against high cholesterol levels (hyperlipidemia).<\/li><li>Lithium (anti-mania\/depression) or certain sedative medications.<\/li><li>ACE inhibitors\u00a0(blood pressure lowering).<\/li><li>Non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0) (certain pain\/inflammation agents).<\/li><li>Barbiturates, are used for sleep problems or anxiety.<\/li><li>Insulin\u00a0and diabetes drugs.<\/li><li>Steroids, are used to treat many different conditions, such as rheumatism,\u00a0arthritis,\u00a0allergies\u00a0, skin problems,\u00a0asthma,\u00a0and a certain type of blood disorder.<\/li><li>ACTH, is used to test the function of the adrenal glands.<\/li><li>Medicines are injected for allergic reactions, for example,\u00a0adrenaline\u00a0(also called\u00a0epinephrine\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Sparkal\/Sparkal Mite with food, drink, and alcohol<\/h2>\n\n\n\n<p>Your doctor may have asked you to change your diet slightly and not to eat certain foods that contain a lot of\u00a0potassium.\u00a0Your doctor can tell you what you should not eat.\u00a0If you are unsure about which foods you should avoid, consult your doctor before taking Sparkal\/Sparkal\u00a0Mite.<\/p>\n\n\n\n<p>Your doctor may have asked you to minimize your alcohol intake while taking Sparkal\/Sparkal\u00a0Mite.\u00a0Alcohol can increase the effect of Sparkal\/Sparkal\u00a0Mite, which may make you feel dizzy when you stand up quickly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Usually, your doctor will suggest that you take another medicine instead of Sparkal\/Sparkal\u00a0Mite\u00a0because Sparkal\/Sparkal\u00a0Mite\u00a0is not recommended during pregnancy.\u00a0This is because Sparkal\/Sparkal\u00a0Mite\u00a0passes to the fetus and can cause harm to the fetus and the newborn if used during the last 6 months of pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Tell your doctor if you are breastfeeding or intend to start breastfeeding.\u00a0Sparkal\/Sparkal\u00a0Mite\u00a0is not recommended during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>If you experience\u00a0side effects\u00a0such as dizziness, fatigue, and weakness, do not drive or use machinery.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Sparkal\/Sparkal Mite contains lactose and wheat starch<\/h2>\n\n\n\n<p>If you have an intolerance to certain sugars, you should consult your doctor before taking this medication.<\/p>\n\n\n\n<p>This medicine contains only very low levels of gluten (from wheat starch).&nbsp;It is very unlikely to cause problems if you have gluten intolerance (&nbsp;celiac disease&nbsp;).<\/p>\n\n\n\n<p>One Sparkal tablet contains no more than 8.3 micrograms of gluten and one Sparkal&nbsp;Mite&nbsp;tablet contains no more than 4.2 micrograms of gluten.<\/p>\n\n\n\n<p>If you are allergic to wheat (a disease other than gluten intolerance) you should not use this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>Sparkal\/Sparkal&nbsp;Mite<\/p>\n\n\n\n<p>Always use this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><em>High blood pressure:<\/em>&nbsp;Usual&nbsp;dose&nbsp;is 1 tablet of Sparkal&nbsp;Mite&nbsp;daily.<\/p>\n\n\n\n<p><em>Edema&nbsp;in heart failure:<\/em>&nbsp;Usual starting dose is 1 tablet of Sparkal daily (equivalent to 2 tablets of Sparkal&nbsp;Mite&nbsp;).&nbsp;The dose&nbsp;for long-term treatment depends on how you respond to the treatment and is determined by the doctor.<\/p>\n\n\n\n<p><em>Edema&nbsp;in cirrhosis of the liver:<\/em>&nbsp;Usual starting dose is 1 tablet of Sparkal (equivalent to 2 tablets of Sparkal&nbsp;Mite&nbsp;) daily.&nbsp;The dose&nbsp;for long-term treatment depends on how you respond to the treatment and is determined by the doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor, or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed tablet.\u00a0Return to a regular schedule as soon as possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>Do not stop taking Sparkal\/Sparkal&nbsp;Mite&nbsp;without talking to your doctor.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious\u00a0side effects, contact the doctor immediately if you experience any of the following symptoms:<\/strong><\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity reaction\u00a0with fever, rash, swelling, and sometimes drop in blood pressure<\/li><li>Sparkal\/Sparkal\u00a0Mite\u00a0can in rare cases affect the white\u00a0blood cells\u00a0so that the defense against infection deteriorates.\u00a0If you get an\u00a0infection\u00a0with symptoms such as fever with a greatly worsened general condition or fever with local symptoms of infection such as sore throat\/pharynx\/mouth or vomiting, you should see a doctor as soon as possible so that a lack of\u00a0white blood cells\u00a0(\u00a0agranulocytosis\u00a0) can be ruled out via a blood test.\u00a0It is important that you then information about your medication.<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute\u00a0respiratory distress syndrome (signs of this are severe shortness of breath, fever, weakness, and confusion).<\/li><\/ul>\n\n\n\n<p><strong>Other side effects:<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 users):<\/em><\/p>\n\n\n\n<p>Weakness, fatigue, loss of appetite, dizziness, headache, effect on heart rhythm, nausea, diarrhea, abdominal pain, skin rash (exanthema),\u00a0itching, shortness of breath, increased blood sugar levels, increased amount of\u00a0uric acid\u00a0in the blood, pain in legs and arms.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 users):<\/em><\/p>\n\n\n\n<p>Joint pain, chest and back pain,\u00a0impotence, dizziness due to a drop in blood pressure when standing up quickly, palpitations, chest pain, &#8220;and crawling&#8221;, gastrointestinal disturbances such as bad taste in the mouth, vomiting, feeling full, constipation and flatulence, hiccups, thirst, stomach ache, nasal congestion,\u00a0gout.\u00a0Nausea, malaise, muscle weakness, and confusion due to low sodium levels in the blood.\u00a0General weakness, dizziness, and fainting due to lack of fluids, and dehydration (\u00a0dehydration\u00a0).\u00a0Muscle cramps, sleep disturbances, nervousness, depression, mental confusion, urination problems, and visual disturbances.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 users):<\/em><\/p>\n\n\n\n<p>Fainting,\u00a0anemia\u00a0and other blood changes, reduced level of alertness, gastrointestinal bleeding,\u00a0redness, hypersensitivity to sunlight, vessel wall inflammation, jaundice (cholestasis), cough, and impaired kidney function.\u00a0Muscle weakness, confusion, and difficulty speaking due to high potassium levels in the blood.<\/p>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users):<\/em><\/p>\n\n\n\n<p>Skin and lip cancer (Non-&nbsp;melanoma&nbsp;skin cancer).&nbsp;Decreased vision or pain in the eyes due to high pressure (possible sign of fluid accumulation in the eye (between the choroid and sclera) or&nbsp;acute&nbsp;narrow-angle glaucoma&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sparkal\/Sparkal Mite<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances areSparkal: 5 mg (amiloride hydrochloride) + 50 mg (\u00a0hydrochlorothiazide\u00a0)Sparkal Mite: 2.5 mg (amiloride hydrochloride) + 25 mg (\u00a0hydrochlorothiazide\u00a0).<\/li><li>Other ingredients\/excipient(s) are\u00a0lactose monohydrate, magnesium stearate, gelatin, talc, and wheat starch.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Sparkal: A pale yellow, round, flat scored tablet, coded EV 7 on one side and GEA on the other.&nbsp;Diameter: 8.5 mm.<\/li><li>Sparkal Mite: A pale yellow, round, flat scored tablet, coded EZ 3 on one side and GEA on the other.&nbsp;Diameter: 7 mm.<\/li><\/ul>\n\n\n\n<p>Polyethylene tablet container<\/p>\n\n\n\n<p>Cans of 30, 100, and 250 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Hexal A\/S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sparkal\/Sparkal\u00a0Mite\u00a0is used for the treatment of high\u00a0blood pressure\u00a0,\u00a0edema\u00a0(fluid accumulation in the\u00a0tissues\u00a0) due to\u00a0heart failure\u00a0and cirrhosis with fluid in the abdominal cavity.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[10656,3664,3666,24583,24586,24589,10658,24584,24587,24585],"class_list":["post-23465","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-amiloride-hydrochloride","tag-hydrochlorothiazide","tag-hydrochlorothiazide-side-effects","tag-sparkal","tag-sparkal-mite","tag-sparkal-mite-side-effects","tag-what-amiloride-hydrochloride-is-used-for","tag-what-is-sparkal","tag-what-is-sparkal-mite","tag-what-sparkal-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23465","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23465"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23465\/revisions"}],"predecessor-version":[{"id":23506,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23465\/revisions\/23506"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23465"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23465"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23465"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}