{"id":23375,"date":"2022-07-28T06:20:00","date_gmt":"2022-07-28T06:20:00","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23375"},"modified":"2022-07-29T11:10:27","modified_gmt":"2022-07-29T11:10:27","slug":"solu-cortef","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/solu-cortef\/","title":{"rendered":"Solu-Cortef &#8211; Hydrocortisone sodium succinate uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg, 250 mg, 1g\u00a0\u00a0powder, and liquid for\u00a0injection, solution<br>hydrocortisone sodium succinate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Solu-Cortef is and what it is used for<\/h2>\n\n\n\n<p>Solu-Cortef contains hydrocortisone sodium succinate and belongs to a group of medicines called\u00a0corticosteroids.\u00a0Hydrocortisone\u00a0is a\u00a0hormone\u00a0that occurs naturally in the body, it is normally formed in the\u00a0adrenal cortex.<\/p>\n\n\n\n<p>Solu-Cortef is used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>to replace\u00a0hydrocortisone\u00a0when the\u00a0adrenal cortex\u00a0for some reason does not produce enough\u00a0hydrocortisone<\/li><li>for example\u00a0during surgery when hydrocortisone reserves are insufficient<\/li><li>shock treatment together with other treatment<\/li><li>life-threatening allergic reactions (\u00a0anaphylaxis\u00a0with fever, rash, swelling, and sometimes drop in blood pressure)<\/li><li>severe\u00a0hypersensitivity\u00a0reaction<\/li><li>severe reactions after insect and snake bites<\/li><li>severe asthma attacks<\/li><li>SLE\u00a0(connective tissue disease)<\/li><li>congenital enlargement of the\u00a0adrenal cortex\u00a0a<\/li><li>leukemia\u00a0and malignant\u00a0lymphoma<\/li><\/ul>\n\n\n\n<p>The hydrocortisone sodium succinate contained in Solu-Cortef may also be approved to treat other conditions not listed in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you are given Solu-Cortef<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Solu-Cortef<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to hydrocortisone sodium succinate or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before being given Solu-Cortef if you have any of the following diseases or conditions:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>osteoporosis<\/li><li>recently undergone intestinal surgery<\/li><li>mental disorders<\/li><li>ulcers\u00a0or other serious stomach or intestinal problems<\/li><li>tuberculosis<\/li><li>diabetes<\/li><li>high\u00a0blood pressure<\/li><li>heart failure\u00a0or another cardiovascular disease<\/li><li>infection<\/li><li>tumor\u00a0of the adrenal medulla (\u00a0phaeochromocytoma\u00a0)<\/li><li>diseases of the liver, kidneys, and biliary tract<\/li><li>chicken pox or measles<\/li><li>underactive\u00a0thyroid\u00a0(\u00a0hypothyroidism\u00a0)<\/li><li>seizures (\u00a0epilepsy\u00a0)<\/li><li>glaucoma\u00a0(increased pressure in the eye)<\/li><li>herpes infection in the eye<\/li><li>damage to the\u00a0optic nerve\u00a0or cataracts (can be seen as vision loss)<\/li><li>Central serous\u00a0retinopathy\u00a0is an eye disease that causes vision loss<\/li><li>blood clots in blood vessels or have an increased sensitivity to forming blood clots<\/li><li>a neuromuscular disease called\u00a0myasthenia gravis, as it can make you more susceptible to\u00a0acute\u00a0generalized muscle disease.<\/li><\/ul>\n\n\n\n<p><em>Susceptibility&nbsp;to&nbsp;infection<\/em><\/p>\n\n\n\n<p>This medicine may increase your susceptibility to\u00a0infection\u00a0or mask symptoms of\u00a0infection.\u00a0To avoid possible serious consequences due to this, tell your doctor immediately if you develop any symptoms of\u00a0infection\u00a0during treatment.<\/p>\n\n\n\n<p><em>Stress<\/em><\/p>\n\n\n\n<p>Talk to your doctor if you are exposed or will be exposed to an unusual amount of stress during treatment.&nbsp;It may be necessary to adjust your treatment.<\/p>\n\n\n\n<p><em>Mental disorders<\/em><\/p>\n\n\n\n<p>Psychiatric disorders, such as elation, insomnia, mood swings, personality changes, deep depression, or overt psychotic symptoms may occur or worsen with the use of this medicine.\u00a0If you experience similar symptoms, contact your doctor as your treatment may need to be adjusted.<\/p>\n\n\n\n<p><em>Effects on&nbsp;blood pressure&nbsp;and laboratory values<\/em><\/p>\n\n\n\n<p>In rare cases, high\u00a0doses\u00a0or long-term use of this medicine can increase\u00a0blood pressure, increase\u00a0sodium\u00a0and water retention in the body (swelling), increase\u00a0potassium\u00a0and calcium excretion or increase blood fat values.\u00a0To manage these\u00a0side effects, your doctor may ask you to review your diet.<\/p>\n\n\n\n<p><em>Other<\/em><\/p>\n\n\n\n<p>Contact a doctor if you experience blurred vision or other visual disturbances.<\/p>\n\n\n\n<p>High-dose or long-term corticosteroid therapy can cause&nbsp;Kaposi&#8217;s sarcoma&nbsp;(a rare tumor disease) or&nbsp;epidural&nbsp;lipomatosis (accumulation of fatty tissue in the area around the spinal canal).&nbsp;You will be monitored for these effects and, if necessary, your doctor will adjust the treatment accordingly.&nbsp;Long-term use of this drug can also impair the body&#8217;s adrenal function and cortisol production.&nbsp;To reduce the risk of such symptoms, treatment will be terminated by gradually tapering the&nbsp;dose&nbsp;a.<\/p>\n\n\n\n<p>The doctor may need to monitor your treatment more closely, change the&nbsp;dose&nbsp;or give you a different medicine.<\/p>\n\n\n\n<p>Solu-Cortef should not be used in the treatment of complications after severe head injuries or\u00a0strokes, as you will probably not benefit from the treatment and it may even be harmful.<\/p>\n\n\n\n<p>Tell the doctor that you have received Solu-Cortef if you are going to undergo a skin test, e.g.&nbsp;prick test for&nbsp;allergy&nbsp;or tuberculin test.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>In children, long-term use of high&nbsp;doses&nbsp;of this medicine may cause impaired growth or increased pressure (symptoms: headache, nausea\/vomiting, balance disorder, reduced level of consciousness).&nbsp;You should carefully observe your child for signs and symptoms of these conditions.<\/p>\n\n\n\n<p>If&nbsp;hydrocortisone&nbsp;is given to a premature infant, the function and structure of the heart may need to be monitored.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Solu-Cortef<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, even those without a prescription.<\/p>\n\n\n\n<p><strong>Tell your doctor if you are simultaneously using:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs that are partly used in the treatment of\u00a0epilepsy\u00a0and partly as fast-acting anesthetics (\u00a0phenytoin, carbamazepine, and\u00a0barbiturates\u00a0such as phenobarbital)<\/li><li>medicine against bacterial infection (rifampicin).<\/li><li>certain anti-\u00a0HIV\u00a0medicines (cobicistat).\u00a0Your doctor may want to monitor you closely if you are taking these medicines<\/li><li>certain antifungal medicines (eg\u00a0ketoconazole, itraconazole)<\/li><li>certain\u00a0antibiotics\u00a0such as\u00a0can be used for the treatment of respiratory tract infections or\u00a0infections\u00a0in the throat, sinuses and skin, and soft tissues (e.g. clarithromycin)<\/li><li>blood-thinning medicines taken by mouth to prevent blood clotting (eg\u00a0warfarin\u00a0)<\/li><li>anticholinergics used against, among other things\u00a0certain eye diseases,\u00a0asthma, COPD,\u00a0Parkinson&#8217;s disease,\u00a0and inhibition of mucus formation<\/li><li>drugs against the neuromuscular disease\u00a0myasthenia gravis<\/li><li>medicines used to treat high blood sugar.\u00a0The doctor may need to adjust\u00a0the\u00a0dose<\/li><li>certain breast cancer medicines (aromatase inhibitors)<\/li><li>medicines for\u00a0heart failure\u00a0and\u00a0atrial fibrillation\u00a0(\u00a0digoxin\u00a0)<\/li><li>drugs for pain (\u00a0NSAIDs\u00a0)<\/li><li>potassium-lowering agents (eg,\u00a0diuretics\u00a0to treat high\u00a0blood pressure\u00a0)<\/li><\/ul>\n\n\n\n<p>Solu-Cortef can be affected by or affect the effect of many other medicines.&nbsp;<strong>Treating physicians must therefore be aware of all other medications.&nbsp;This applies to both prescription and non-prescription drugs.<\/strong><\/p>\n\n\n\n<p><strong>Always tell the doctor who prescribes you another medicine that you are being treated with Solu-Cortef.<\/strong><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Solu-Cortef with food, drink, and alcohol<\/h2>\n\n\n\n<p>Avoid drinking grapefruit juice during treatment.&nbsp;Grapefruit juice may increase the&nbsp;side effects&nbsp;of this medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before you are given this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em>\u00a0<br>There is a risk that the fetus will be affected.\u00a0With long-term treatment, low birth weight has been seen in infants.\u00a0Therefore, do not use Solu-Cortef during pregnancy other than on a specific\u00a0prescription\u00a0from a doctor.<\/p>\n\n\n\n<p>Solu-Cortef 1 g contains the preservative benzyl alcohol (see &#8220;Solu-Cortef 1 g powder and liquid for\u00a0injection, the solution contains benzyl alcohol&#8221;).<\/p>\n\n\n\n<p><em>Breastfeeding<\/em><br>There is a risk that a child who is breastfed will be affected as small amounts of\u00a0hydrocortisone\u00a0pass into breast milk.\u00a0Therefore, do not use Solu-Cortef during breastfeeding other than on a specific\u00a0prescription\u00a0from a doctor.<\/p>\n\n\n\n<p>Solu-Cortef 1 g contains the preservative benzyl alcohol (see &#8220;Solu-Cortef 1 g powder and liquid for\u00a0injection, the solution contains benzyl alcohol&#8221;).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Solu-Cortef does not usually affect the ability to drive or use machines.\u00a0However, you may experience\u00a0side effects\u00a0such as dizziness, visual disturbances, and fatigue, which can therefore affect driving ability.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Solu-Cortef 1 g powder and liquid for injection, the solution contains benzyl alcohol<\/h2>\n\n\n\n<p>Solu-Cortef 1 g contains 72 mg of benzyl alcohol per 8 ml of solution, which corresponds to 9 mg\/ml of benzyl alcohol.<\/p>\n\n\n\n<p>Benzyl alcohol can cause allergic reactions.<\/p>\n\n\n\n<p>Benzyl alcohol is associated with the risk of serious&nbsp;side effects&nbsp;such as breathing difficulties in young children.&nbsp;Do not give the medicine to newborns (up to 4 weeks of age) and no longer than 1 week to younger children (younger than 3 years) unless a doctor has prescribed it.<\/p>\n\n\n\n<p>Consult a doctor or pharmacist before using this medicine if you have impaired liver or kidney function or if you are pregnant or breastfeeding.&nbsp;Large amounts of benzyl alcohol can be stored in the body and cause&nbsp;side effects&nbsp;(metabolic&nbsp;acidosis&nbsp;).<\/p>\n\n\n\n<p><strong>Solu-Cortef&nbsp;<\/strong><strong>contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>Solu-Cortef 100 mg contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per bottle, i.e. is second<\/p>\n\n\n\n<p>next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<p>Solu-Cortef 250 mg contains 30 mg of&nbsp;sodium&nbsp;(the main ingredient in common\/table salt) per bottle.&nbsp;This corresponds to 1.5% of the maximum recommended daily intake of&nbsp;sodium&nbsp;for adults.<\/p>\n\n\n\n<p>Solu-Cortef 1 g contains 109.3 mg of&nbsp;sodium&nbsp;(the main ingredient in common\/table salt) per bottle.&nbsp;This corresponds to 5.5% of the maximum recommended daily intake of&nbsp;sodium&nbsp;for adults.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Solu-Cortef is given to you<\/h2>\n\n\n\n<p>Solu-Cortef is given as an\u00a0injection.\u00a0Your doctor will decide where to\u00a0inject, how much medicine, and how many\u00a0injections\u00a0to get, depending on the condition being treated.\u00a0Your doctor will inject as low a\u00a0dose\u00a0for as short a time as possible to effectively relieve your symptoms.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you are given too much Solu-Cortef<\/h2>\n\n\n\n<p>As this medicine will be given to you by your doctor, it is unlikely that you will be given too much medicine.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The&nbsp;side effects&nbsp;that can occur with long-term treatment are very rare with short-term treatment.<\/p>\n\n\n\n<p>Among other things, the&nbsp;side effects&nbsp;listed below can occur.<\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>reduce your resistance to\u00a0infection\u00a0or hide or change the signs and symptoms of certain\u00a0infections\u00a0which may make them more difficult to detect, as well as activation\u00a0of\u00a0infection<\/li><li>inhibition of the own\u00a0corticosteroid\u00a0secretion as well as fat accumulation on the torso and face, skin changes, fluid accumulation in the body (so-called Cushing-like symptoms)<\/li><li>worsening of\u00a0diabetes\u00a0or outbreak of\u00a0diabetes\u00a0that has been dormant<\/li><li>growth retardation in children<\/li><li>menstrual disorders<\/li><li>low level of potassium in the blood, impaired excretion of\u00a0sodium\u00a0in the urine<\/li><li>edema, high\u00a0blood pressure,\u00a0heart failure<\/li><li>pinpoint-sized, flat, round, red marks under the skin (\u00a0petechiae\u00a0)<\/li><li>osteoporosis, muscle wasting (reduction of muscle mass)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased risk of blood clots<\/li><li>the clotting ability of the blood may increase<\/li><li>allergic or allergy-like reactions with spasms in the trachea<\/li><li>negative nitrogen balance caused by the breakdown of muscle proteins<\/li><li>calcium loss from the skeleton<\/li><li>mental disorders<\/li><li>increased pressure in the eyes, posterior cataracts with symptoms such as blurred vision and sensitivity to bright light, protruding eyes<\/li><li>wounds, holes (\u00a0perforation\u00a0) and possibly bleeding from the gastrointestinal tract,\u00a0inflammation\u00a0of the pancreas<\/li><li>thinned skin, impaired wound healing<\/li><li>loss of bone and\u00a0cartilage\u00a0(aseptic bone necrosis), muscle wasting (\u00a0myopathy\u00a0), rupture of tendons, spontaneous fractures<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased pressure in the skull, due to the increased pressure, various&nbsp;side effects&nbsp;can occur such as headaches, vomiting, convulsions, visual disturbances, etc.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased number of\u00a0white blood cells\u00a0(\u00a0leukocytosis\u00a0)<\/li><li>pheochromocytoma-related crisis (symptoms such as palpitations, headache, and sweating)<\/li><li>dyslipidemia<\/li><li>increased appetite<\/li><li>affective disorder (including depression,\u00a0euphoria, affect lability, drug addiction, suicidal ideation)<\/li><li>mental disorders (including mania, delusions, hallucinations, and schizophrenia)<\/li><li>personality change<\/li><li>sleep disorders<\/li><li>Mood swings<\/li><li>confusion<\/li><li>concern<\/li><li>abnormal behavior<\/li><li>irritability accumulation of adipose tissue in isolated places on the body<\/li><li>memory loss<\/li><li>deterioration of short-term memory<\/li><li>dizziness<\/li><li>headache<\/li><li>cramps<\/li><li>an eye disease that causes a distorted field of\u00a0vision<\/li><li>blurred vision<\/li><li>hiccup<\/li><li>open stomach<\/li><li>abdominal pain<\/li><li>diarrhea<\/li><li>vomiting<\/li><li>nausea<\/li><li>increased hair growth in women<\/li><li>skin redness<\/li><li>increased sweating<\/li><li>stretch marks<\/li><li>rash<\/li><li>itching<\/li><li>acne<\/li><li>pigment spots<\/li><li>muscle pain<\/li><li>neuropathic joint disease<\/li><li>joint pain<\/li><li>fatigue<\/li><li>malaise<\/li><li>injection site reaction<\/li><li>increase of\u00a0urea\u00a0in the blood<\/li><li>thickening of the heart muscle (\u00a0hypertrophic\u00a0cardiomyopathy\u00a0) in premature infants<\/li><li>weight gain<\/li><\/ul>\n\n\n\n<p>Liver effects have been seen in connection with corticosteroid treatment.\u00a0These changes are usually small, with no other symptoms, and that reverse when treatment is stopped.<\/p>\n\n\n\n<p>If any&nbsp;side effects&nbsp;get worse or if you notice any&nbsp;side effects&nbsp;not mentioned in this information, contact your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Solu-Cortef<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton after EXP.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is hydrocortisone sodium succinate.\u00a0One package contains the equivalent of 100 mg, 250 mg, and 1 g of hydrocortisone sodium succinate.<\/li><li>Other ingredients are (powder): anhydrous sodium dihydrogen phosphate monohydrate, sodium hydroxide, and sodium phosphate (see section 2 &#8220;Solu-Cortef contains sodium&#8221;).<\/li><\/ul>\n\n\n\n<p><em>Solu-Cortef 100 mg and 250 mg<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other ingredients are (&nbsp;diluent&nbsp;): water for injections.<\/li><\/ul>\n\n\n\n<p><em>Solu-Cortef 1 g<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other ingredients are (\u00a0diluent\u00a0): benzyl alcohol, water for injections (see section 2 &#8220;Solu-Cortef 1 g powder and liquid for\u00a0injection, the solution contains benzyl alcohol&#8221;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Powder and liquid for&nbsp;injection&nbsp;in combination packaging.<\/p>\n\n\n\n<p><em>100 mg:<\/em>&nbsp;1&#215;100 mg, 25&#215;100 mg, 100&#215;100 mg.<\/p>\n\n\n\n<p><em>250 mg:<\/em>&nbsp;1&#215;250 mg.<\/p>\n\n\n\n<p><em>1g:<\/em>&nbsp;1x1g.<\/p>\n\n\n\n<p>Not all pack sizes and strengths may be marketed.<br><a><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Solu-Cortef contains hydrocortisone sodium succinate and belongs to a group of medicines called\u00a0corticosteroids\u00a0.\u00a0Hydrocortisone\u00a0is a\u00a0hormone\u00a0that occurs naturally in the body, it is normally formed in the\u00a0adrenal cortex\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24431,24436,24427,24430,24432,24435,24429,24428,24433,24434],"class_list":["post-23375","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-hydrocortisone-sodium-succinate","tag-benefits-of-solu-cortef","tag-hydrocortisone-sodium-succinate","tag-hydrocortisone-sodium-succinate-side-effects","tag-solu-cortef","tag-solu-cortef-side-effects","tag-what-hydrocortisone-sodium-succinate-is-used-for","tag-what-is-hydrocortisone-sodium-succinate","tag-what-is-solu-cortef","tag-what-solu-cortef-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23375","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23375"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23375\/revisions"}],"predecessor-version":[{"id":23403,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23375\/revisions\/23403"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23375"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23375"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23375"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}