{"id":23271,"date":"2022-07-26T06:23:52","date_gmt":"2022-07-26T06:23:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23271"},"modified":"2022-07-27T06:15:52","modified_gmt":"2022-07-27T06:15:52","slug":"skinoren","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/skinoren\/","title":{"rendered":"Skinoren &#8211; Azelaic acid uses, dose and side effects"},"content":{"rendered":"\n<p>20%&nbsp;cream<br>azelaic acid<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Skinoren is and what it is used for<\/h2>\n\n\n\n<p>Skinoren\u00a0cream\u00a0contains azelaic acid, which occurs naturally in the human body and which prevents the growth of the bacteria that are active in the occurrence of\u00a0acne.\u00a0In addition, Skinoren normalizes the formation of the top skin layer in such a way that blackheads do not form.<\/p>\n\n\n\n<p>Skinoren is used for the treatment of mild to moderate\u00a0acne.<\/p>\n\n\n\n<p>Azelaic acid contained in Skinoren\u00a0cream\u00a0may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Skinoren<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Skinoren<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to azelaic acid or any other ingredient (especially propylene glycol) of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Skinoren.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have\u00a0asthma.\u00a0Exacerbation of\u00a0asthma\u00a0in patients treated with azelaic acid has been reported rarely.<\/li><li>Skinoren\u00a0cream\u00a0should only be used\u00a0externally.<\/li><li>The cream\u00a0should not come into contact with the eyes, mouth, or mucous membranes.<\/li><li>If the preparation accidentally comes into contact with the eyes, mouth, or mucous membranes, rinse with plenty of water.\u00a0If eye irritation persists, contact a doctor.<\/li><li>In case of fragile, thin, or damaged skin, Skinoren\u00a0cream\u00a0should be used with caution.<\/li><li>Hands must be washed after each treatment with Skinoren\u00a0cream.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Skinoren&nbsp;cream&nbsp;is not recommended for children under 12 years of age because there is no data on efficacy and safety for them.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Skinoren<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>There is no information on whether Skinoren affects the effect or safety of other medicines given at the same time or whether Skinoren is affected by other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<br>There is limited experience with the use of the active substance azelaic acid during pregnancy and breastfeeding.<\/p>\n\n\n\n<p>Children should not come into contact with treated skin.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Skinoren does not affect the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Skinoren contains benzoic acid and propylene glycol<\/h2>\n\n\n\n<p>Skinoren&nbsp;cream&nbsp;contains 2 mg of benzoic acid per gram.&nbsp;Benzoic acid can cause local irritation.<\/p>\n\n\n\n<p>Skinoren&nbsp;cream&nbsp;contains 125 mg of propylene glycol per gram.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Skinoren<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor and the directions on the pharmacy label.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Adults<\/strong><br>Skinoren should only be used\u00a0externally.<br>Before using Skinoren, the skin must be thoroughly cleaned with water or a mild skin cleanser and dried.<\/p>\n\n\n\n<p>Skinoren is spread on the skin areas to be treated according to the doctor&#8217;s\u00a0prescription, usually 2 times a day (morning and evening).\u00a0The cream\u00a0should be gently massaged into the skin.\u00a0About 2.5 cm of\u00a0cream\u00a0is enough for the whole face.<\/p>\n\n\n\n<p>If skin irritation occurs (see section 4. Possible\u00a0side effects\u00a0), you can use a smaller amount of Skinoren or you can just treat the skin once a day until the irritation stops.\u00a0You may need to take a break from treatment for a few days.<\/p>\n\n\n\n<p>It is important to use Skinoren&nbsp;cream&nbsp;regularly throughout the treatment period.&nbsp;This treatment time varies from person to person and also depends on how severe the skin problems are.<br>Normally an improvement is seen after about 4 weeks, but to achieve the best possible results, the treatment should be continued for several months depending on how you respond to the treatment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Dose adjustment is not necessary when Skinoren&nbsp;cream&nbsp;is given to adolescents between 12 and 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Skinoren&nbsp;<\/h2>\n\n\n\n<p>If you have used too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>It is unlikely that too much Skinoren&nbsp;cream&nbsp;will lead to poisoning symptoms.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Skinoren<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.\u00a0Continue the treatment as prescribed by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Skinoren<\/h2>\n\n\n\n<p>If you stop treatment, your skin problems may worsen.&nbsp;Consult your doctor before stopping treatment.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Local skin irritation (usually with a stinging\/stinging sensation) occurs especially at the beginning of the treatment but usually decreases during the treatment.<\/p>\n\n\n\n<p><em>Angioedema<\/em>&nbsp;:<\/p>\n\n\n\n<p>Stop taking Skinoren&nbsp;cream&nbsp;and contact your doctor immediately if you experience any of the following symptoms (&nbsp;angioedema&nbsp;):<\/p>\n\n\n\n<p>swelling of the face, tongue, or throat;\u00a0difficulty swallowing;\u00a0hives,\u00a0and difficulty breathing.<\/p>\n\n\n\n<p>The following\u00a0side effects\u00a0are based on reports from\u00a0clinical studies\u00a0and from follow-up after the approval of Skinoren\u00a0cream.\u00a0Side effects\u00a0are listed according to how often they are reported to occur.<\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 in 10 users):<\/strong><br>At the site of administration: Stinging\/stinging sensation,\u00a0itching, redness of the skin.<\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 users):<\/strong><br>At the site of administration: Scaling, pain, dry skin, skin discoloration, skin irritation.<\/p>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people):<\/strong><br>Seborrhea\u00a0(increased sebum production, giving the skin an oily appearance),\u00a0acne, and loss of skin pigment.<br>At the site of administration: Numbness, skin inflammation, discomfort,\u00a0edema\u00a0(abnormal accumulation of fluid in the body).<\/p>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users):<\/strong><br>Drug hypersensitivity (which may occur together with\u00a0angioedema\u00a0<sup>1<\/sup>, contact eczema\u00a01, eye swelling\u00a01, facial swelling\u00a01\u00a0), aggravated\u00a0asthma,\u00a0hives\u00a01,\u00a0inflammation\u00a0of the lips, skin rash\u00a01.<\/p>\n\n\n\n<p>At the site of administration: the feeling of warmth, blisters,\u00a0eczema, ulcers.<\/p>\n\n\n\n<p><sup>1<\/sup>&nbsp;&nbsp;These&nbsp;side effects&nbsp;have been reported in patients who used Skinoren&nbsp;cream&nbsp;after approval<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Skinoren should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.&nbsp;Store at a maximum of 30\u00b0C.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging after &#8220;Expiry Date&#8221;.<br>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Opened packaging is stable for 6 months.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active ingredient is azelaic acid.&nbsp;1 g of&nbsp;cream&nbsp;contains 200 mg of azelaic acid.<\/li><li>Other ingredients are benzoic acid (E210), cetearyl octanoate + isopropyl myristate (PCL Liquid), glycerol (85%), glycerol stearate + cetearyl alcohol + cetyl palmitate + coconut oil glycerides (CUTINA CBS), propylene glycol, water, stearoyl macrogol glycerides.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Skinoren is a white, opaque\u00a0cream.<br>Ointment tube: 30 g and 50 g.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>LEO Pharma A\/S<\/p>\n\n\n\n<p>Industriparken 55<\/p>\n\n\n\n<p>DK-2750 Ballerup<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong>&nbsp;:<br>LEO Pharma Manufacturing Italy Srl<br>Via E. Schering 21<br>I-20054 Segrate<br>Milano<br>Italy<\/p>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>LEO Pharma AB<\/p>\n\n\n\n<p>Box 404<\/p>\n\n\n\n<p>201 24 Malm\u00f6<\/p>\n\n\n\n<p>Phone: 040-352200<\/p>\n\n\n\n<p>Email: info.se@leo-pharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Skinoren\u00a0cream\u00a0contains azelaic acid, which occurs naturally in the human body and which prevents the growth of the bacteria that are active in the occurrence of\u00a0acne\u00a0.\u00a0In addition, Skinoren normalizes the formation of the top skin layer in such a way that blackheads do not form.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[2915,24333,2918,24338,24334,24337,24332,24331,24335,24336],"class_list":["post-23271","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-azelaic-acid","tag-azelaic-acid-cream","tag-azelaic-acid-side-effects","tag-benefits-of-skinoren","tag-skinoren","tag-skinoren-side-effects","tag-what-azelaic-acid-is-used-for","tag-what-is-azelaic-acid","tag-what-is-skinoren","tag-what-skinoren-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23271","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23271"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23271\/revisions"}],"predecessor-version":[{"id":23315,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23271\/revisions\/23315"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23271"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23271"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23271"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}