{"id":23270,"date":"2022-07-26T06:21:54","date_gmt":"2022-07-26T06:21:54","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23270"},"modified":"2023-02-20T12:52:39","modified_gmt":"2023-02-20T12:52:39","slug":"skilarence","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/skilarence\/","title":{"rendered":"Skilarence &#8211; Dimethyl Fumarate Uses, Dose And Aide Effects"},"content":{"rendered":"\n<p><strong>Skilarence 30 mg&nbsp;Dimethyl Fumarate Enteric Tablet<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Skilarence Is And What Skilarence Used For?<\/h2>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>What is Skilarence<\/strong>?<\/span><\/p>\n\n\n\n<p>Skilarence is a medicine that contains the active substance dimethyl fumarate.&nbsp;Dimethyl fumarate acts on cells in the immune system (the body&#8217;s natural defenses).&nbsp;It changes the activity of the immune system and reduces the production of substances that contribute to causing&nbsp;psoriasis.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">What Skilarence is used for<\/span><\/strong>:<\/p>\n\n\n\n<p><strong>Skilarence tablets are used to treat moderate to severe plaque psoriasis in adults.\u00a0Psoriasis\u00a0is a disease that causes thickened, inflamed, red areas of the skin, often covered in silvery scales.<\/strong><\/p>\n\n\n\n<p>After starting treatment with this medicine, improvement is generally seen as early as week 3 and improves over time.\u00a0Experience with other medicines containing dimethyl fumarate shows the effect of the treatment for at least up to 24 months.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before You Take Skilarence?<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Skilarence:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to dimethyl fumarate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have severe problems with your stomach or intestines<\/li><li>If you have severe liver or kidney problems<\/li><li>If you are pregnant or breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Precautions:<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Investigations<\/span><\/strong><\/p>\n\n\n\n<p>Skilarence may cause problems with the blood, liver, or kidneys.&nbsp;You will have blood and urine samples before treatment and then regularly during treatment to check that you do not develop such complications and can continue to take this medicine.&nbsp;Depending on the results of these blood and urine tests, the doctor may lower the&nbsp;dose&nbsp;of Skilarence or stop the treatment.<\/p>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>Infection\u00a0you<\/strong><\/span><\/p>\n\n\n\n<p>White blood cells\u00a0help your body fight\u00a0infection.\u00a0Skilarence can cause a reduced number of\u00a0white blood cells.\u00a0Talk to your doctor if you think you may have an\u00a0infection.\u00a0Symptoms may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">Pain<\/a><\/li><li>Muscle aches<\/li><li>Headache<\/li><li>Decreased appetite<\/li><li>General weakness<\/li><\/ul>\n\n\n\n<p>If you have a serious\u00a0infection before starting treatment with Skilarence or during treatment, your doctor may advise you not to take this medicine until the\u00a0infection\u00a0has cleared.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Diseases of the gastrointestinal tract:<\/span><\/strong><\/p>\n\n\n\n<p>Tell your doctor if you have problems with your stomach or intestines.\u00a0The doctor will tell you what measures you must take during treatment with Skilarence.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People:<\/h2>\n\n\n\n<p>Children and adolescents under 18 should not take this medicine as it has not been studied in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Skilarence:<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Dimethyl fumarate or other fumarates.\u00a0<\/strong>The active ingredient in Skilarence, dimethyl fumarate, is also used in other medicines such as tablets, ointments, and baths.\u00a0You must avoid using other products containing fumarates to prevent taking too much.<\/li><li>Other medicines for treating\u00a0psoriasis,\u00a0eg methotrexate,\u00a0retinoids, psoralens, and cyclosporine, or other immunosuppressive medicines or\u00a0cytostatics\u00a0(medicines that affect the immune system).\u00a0If you take these medicines with Skilarence, the risk of\u00a0side effects\u00a0affecting the immune system may increase.<\/li><li>Other medicines that can affect kidney function, such as e.g.\u00a0methotrexate or cyclosporine (used for\u00a0psoriasis\u00a0),\u00a0aminoglycosides\u00a0(used for\u00a0infection\u00a0),\u00a0diuretics\u00a0(which increase urine output), non-steroidal anti-inflammatory drugs (used for pain) or lithium (used for\u00a0bipolar disorder\u00a0and depression). Taking this medicine with Skilarence may increase the risk of\u00a0side effects\u00a0in the kidneys.<\/li><\/ul>\n\n\n\n<p>If you get severe or prolonged diarrhea with Skilarence, it is possible that other medicines will not work as well as they would otherwise.\u00a0<strong>Talk to your doctor if you have severe diarrhea and are concerned that other medicines you take may not work<\/strong>.<\/p>\n\n\n\n<p>Especially if you are taking birth control (\u00a0birth control pills\u00a0), as the effect may be reduced, and you may need to use an additional\u00a0barrier\u00a0method to prevent pregnancy.\u00a0Read the instructions in the package insert for the contraceptive you are using.<\/p>\n\n\n\n<p>If you need to be vaccinated, talk to your doctor.&nbsp;Certain types of vaccines (live vaccines) can cause&nbsp;infection&nbsp;if used during treatment with Skilarence.&nbsp;The doctor can advise you on what is most suitable.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ski Clearance With Alcohol:<\/h2>\n\n\n\n<p>Avoid strong alcoholic drinks (more than 50 ml of spirits containing more than 30% alcohol by volume) during treatment with Skilarence, as alcohol can affect this medicine.&nbsp;This can cause stomach and intestinal problems.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding:<\/h2>\n\n\n\n<p>Do not take Skilarence if you are pregnant or trying to become pregnant because Skilarence may harm your baby.&nbsp;Use effective contraception to avoid pregnancy during treatment with Skilarence (see also &#8220;Other medicines and Skilarence&#8221; above).&nbsp;Do not breastfeed during treatment with Skilarence.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving Ability And Use Of Machinery:<\/h2>\n\n\n\n<p>Skilarence may have a minor effect on the ability to drive and use machines.&nbsp;You may feel dizzy or tired after taking Skilarence.&nbsp;If you are affected, be careful when driving or using machines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Skilarence Contains Lactose:<\/h2>\n\n\n\n<p>Skilarence contains\u00a0lactose.\u00a0If you are intolerant to certain sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Skilarence contains\u00a0sodium<\/strong>: This medicine contains less than 1 mmol (23 mg)\u00a0of sodium\u00a0per tablet, i.e. it is almost &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Take Skilarence?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine as directed by your doctor or pharmacist.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li><strong>Dose<\/strong><ul><li>The doctor will start your treatment with a low\u00a0dose\u00a0(30 mg Skilarence tablets).\u00a0This helps to reduce the risk of stomach upset and other\u00a0side effects.\u00a0Dose\u00a0one will be increased each week according to the table below (change to 120 mg Skilarence tablets from week 4).<\/li><\/ul><\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\">Treatment week<\/th><th scope=\"col\">Tablet strength<\/th><th scope=\"col\">Number of tablets to be taken during the day<\/th><th scope=\"col\">Number of tablets per day<\/th><th scope=\"col\">Total daily dose<\/th><\/tr><\/thead><tbody><tr><td>&nbsp;<\/td><td>&nbsp;<\/td><td>Breakfast<\/td><td>Lunch<\/td><td>Evening meal<\/td><td><\/td><td><\/td><\/tr><tr><td>1<\/td><td>30 mg<\/td><td>&#8211;<\/td><td>&#8211;<\/td><td>1<\/td><td>1<\/td><td>30 mg<\/td><\/tr><tr><td>2<\/td><td>30 mg<\/td><td>1<\/td><td>&#8211;<\/td><td>1<\/td><td>2<\/td><td>60 mg<\/td><\/tr><tr><td>3<\/td><td>30 mg<\/td><td>1<\/td><td>1<\/td><td>1<\/td><td>3<\/td><td>90 mg<\/td><\/tr><tr><td>4<\/td><td>120 mg<\/td><td>&#8211;<\/td><td>&#8211;<\/td><td>1<\/td><td>1<\/td><td>120 mg<\/td><\/tr><tr><td>5<\/td><td>120 mg<\/td><td>1<\/td><td>&#8211;<\/td><td>1<\/td><td>2<\/td><td>240 mg<\/td><\/tr><tr><td>6<\/td><td>120 mg<\/td><td>1<\/td><td>1<\/td><td>1<\/td><td>3<\/td><td>360 mg<\/td><\/tr><tr><td>7<\/td><td>120 mg<\/td><td>1<\/td><td>1<\/td><td>2<\/td><td>4<\/td><td>480 mg<\/td><\/tr><tr><td>8<\/td><td>120 mg<\/td><td>2<\/td><td>1<\/td><td>2<\/td><td>5<\/td><td>600 mg<\/td><\/tr><tr><td>9+<\/td><td>120 mg<\/td><td>2<\/td><td>2<\/td><td>2<\/td><td>6<\/td><td>720 mg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The doctor will check how your condition improves after taking Skilarence and if you have any\u00a0side effects.\u00a0If you experience serious\u00a0side effects\u00a0after a dose increase, the doctor may recommend temporarily returning to the last\u00a0dose.<\/p>\n\n\n\n<p>If the\u00a0side effects\u00a0do not bother you, the\u00a0dose\u00a0increases until your condition is controlled.\u00a0You may not need the maximum\u00a0dose\u00a0of 720 mg per day.\u00a0When your condition has improved enough, the doctor will consider how to gradually reduce the daily dose of Skilarence to the\u00a0dose\u00a0you need to maintain the improvement.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Take The Tablets?<\/h2>\n\n\n\n<p>Swallow the Skilarence tablets whole with liquid.&nbsp;Take the tablets during or immediately after a meal.&nbsp;The tablets should not be crushed, split, dissolved, or chewed as they have a special coating to prevent stomach irritation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Have Taken Too Much Skilarence:<\/h2>\n\n\n\n<p>If you think you have taken too many tablets, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Skilarence:<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.\u00a0Take the next\u00a0dose\u00a0at the usual time and continue to take medicine exactly as described in this leaflet or as your doctor prescribes.\u00a0Ask your doctor or pharmacist if you are unsure. If you have any further questions about this medicine, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Skilarence Side Effects:<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.\u00a0Some side effects, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reddening\u00a0of the face or body (erythema)<\/li><li>Diarrhea<\/li><li>Upset stomach<\/li><li>Nausea usually get better as treatment continues.<\/li><\/ul>\n\n\n\n<p><strong>The most serious\u00a0side effects\u00a0of Skilarence are an\u00a0allergy\u00a0or\u00a0hypersensitivity reaction,\u00a0kidney failure\u00a0or a kidney disease called Fanconi syndrome, or a serious brain infection<\/strong> called\u00a0progressive\u00a0multifocal\u00a0leukoencephalopathy (PML).\u00a0These have been reported (occurring in an unknown number of users).\u00a0For symptoms, see below.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Allergy\u00a0or\u00a0hypersensitivity\u00a0reaction<\/span><\/strong><\/p>\n\n\n\n<p>Allergic\u00a0or\u00a0hypersensitivity reactions\u00a0are rare but can be very serious.\u00a0Redness\u00a0of the face or body is a common\u00a0side effect\u00a0that may occur in more than 1 in 10 users.\u00a0But if you show\u00a0redness\u00a0and any of the following signs:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Wheezing (breath sounds), difficulty breathing, or shortness of breath<\/li><li>Swelling of the face, lips, mouth, or tongue<\/li><\/ul>\n\n\n\n<p>stop taking Skilarence and call your doctor right away.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Brain infection called PML<\/span><\/strong>:<\/p>\n\n\n\n<p>Progressive\u00a0multifocal\u00a0leukoencephalopathy (PML) is a rare but serious brain infection that can lead to severe disability or death.\u00a0If you notice DESCRIBED SYMPTOMS, Stop taking Skilarence and talk to your doctor immediately.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>New or worsening weakness in one side of the body<\/li><li>Clumsiness<\/li><li>Vision changes<\/li><li>Impaired thinking or memory<\/li><li>Confusion<\/li><li>Personality changes that last several days<\/li><\/ul>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>Fanconi syndrome<\/strong><\/span>:<\/p>\n\n\n\n<p>Fanconi syndrome is a rare but serious kidney disorder that can occur with Skilarence.\u00a0If you urinate more often or in larger quantities, are thirstier, and drink more than usual, your muscles seem weaker, you break a bone, or you have aches and pains, talk to your doctor as soon as possible, so this can be investigated further.<\/p>\n\n\n\n<p>Talk to your doctor if you get any of the following\u00a0side effects. <\/p>\n\n\n\n<p><strong>Very common\u00a0side effects\u00a0(may affect more than 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reduced number of a type of\u00a0white blood cell\u00a0called\u00a0lymphocytes\u00a0(lymphopenia)<\/li><li>Decreased number of all types of\u00a0white blood cells\u00a0(\u00a0leukopenia\u00a0)<\/li><li>Redness\u00a0of the face or body (erythema)<\/li><li>Diarrhea<\/li><li>Bloated stomach, stomach ache, or stomach cramps<\/li><li>Nausea<\/li><\/ul>\n\n\n\n<p><strong>Common\u00a0side effects\u00a0(may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased number of all types of\u00a0white blood cells\u00a0(\u00a0leukocytosis\u00a0)<\/li><li>Increased number of\u00a0eosinophils, a special type of\u00a0white blood cell<\/li><li>Increased levels of certain\u00a0enzymes\u00a0in the blood (used to check liver function)<\/li><li>Vomiting<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/constipation\/\">Constipation<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/flatulence\/\">Flatulence<\/a><\/li><li>Upset stomach<\/li><li>Indigestion<\/li><li>Decreased appetite<\/li><li>Headache<\/li><li>Fatigue<\/li><li>Weakness<\/li><li>Feeling of warmth<\/li><li>Abnormal sensation in the skin, such as:<ul><li>Itching<\/li><li>Burning<\/li><li>Tingling<\/li><li>Tickling<\/li><li>A stinging sensation<\/li><\/ul><\/li><li>Pink or red spots on the skin (\u00a0erythema\u00a0)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon\u00a0side effects\u00a0(may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>The increased amount of\u00a0protein\u00a0in the urine (\u00a0proteinuria\u00a0)<\/li><li>Elevated\u00a0serum creatinine\u00a0(a substance in the blood used to measure how well your kidneys are working)<\/li><\/ul>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0(may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic skin reactions<\/li><\/ul>\n\n\n\n<p><strong>Very rare\u00a0side effects\u00a0(may affect up to 1 in 10,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute\u00a0lymphoblastic\u00a0leukemia\u00a0(a type of blood <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a>)<\/li><li>Lack of all types of\u00a0blood cells\u00a0(pancytopenia)<\/li><\/ul>\n\n\n\n<p><strong>Frequency not known (cannot be estimated from available data):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Herpes\u00a0zoster (\u00a0shingles\u00a0)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Skilarence?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Use before the expiry date on the carton and the blister after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>No special storage instructions.<\/li><\/ul>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.&nbsp;Ask the pharmacist how to dispose of medicines that are no longer used.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Packaging And Other Information:<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is dimethyl fumarate.&nbsp;One tablet contains 30 mg of dimethyl fumarate.<\/li><li>Other ingredients are&nbsp;lactose monohydrate, microcrystalline cellulose, croscarmellose sodium,&nbsp;colloidal&nbsp;anhydrous silica, magnesium stearate, methacrylic acid ethyl acrylate copolymer (1:1), talc, triethyl citrate, titanium dioxide (E171) and simethicone.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance And Package Sizes Of The Medicine:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Skilarence 30 mg is a white, round tablet with a diameter of approximately 6.8 mm.<\/li><li>Skilarence 30 mg is available in packs of 42, 70, or 210 gastro-resistant tablets.<\/li><li>Not all pack sizes may be marketed.\u00a0The tablets are packed in PVC\/PVCD aluminum blister packs.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Admiral, SA<\/p>\n\n\n\n<p>Ronda General Miter, 151<\/p>\n\n\n\n<p>E-08022 Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>Tel.&nbsp;+34 93 291 30 00<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Industrias Farmac\u00e9uticas Almirall, SA<\/p>\n\n\n\n<p>Ctr.&nbsp;de Martorell 41-61<\/p>\n\n\n\n<p>E-08740 Sant Andreu de la Barca, Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder if you want to know more about this medicine:<\/p>\n\n\n\n<p><strong>Belgi\u00eb\/Belgique\/Belgien\/&nbsp;<\/strong>&nbsp;<strong>Luxembourg\/Luxemburg<\/strong><\/p>\n\n\n\n<p>Almirall NV, T\u00e9l\/Tel: +32 (0)2 771 86 37<\/p>\n\n\n\n<p><strong>Bulgaria\/ Czech Republic\/ Eesti\/ Espa\u00f1a\/ Hrvatska\/ Cyprus\/ Latvija\/ Lietuva\/ Magyarorsz\u00e1g\/ Malta\/ Rom\u00e2nia\/ Slovenija\/ Slovensk\u00e1 republika<\/strong><\/p>\n\n\n\n<p>Almirall, SA, Tel.\/ Tel\/ \u03a4\u03b7\u03bb: +34 93 291 30 00 Tel (\u010cesk\u00e1 republika \/ Slovensk\u00e1 republika): +420 220 990 139<\/p>\n\n\n\n<p><strong>Denmark\/ Norway<\/strong>&nbsp;\/&nbsp;<strong>Finland\/ Finland\/ Sweden<\/strong><\/p>\n\n\n\n<p>Almirall ApS, Tel\/ Puh\/Tel: +45 70 25 75 75<\/p>\n\n\n\n<p><strong>Deutschland<\/strong><\/p>\n\n\n\n<p>Almirall Hermal GmbH, Tel.: +49 (0)40 72704-0<\/p>\n\n\n\n<p><strong>Greece<\/strong><\/p>\n\n\n\n<p>Galenica AE, Tel: +30 210 52 81 700<\/p>\n\n\n\n<p><strong>France<\/strong><\/p>\n\n\n\n<p>Almirall SAS, Tel.: +33(0)1 46 46 19 20<\/p>\n\n\n\n<p><strong>Ireland\/ United Kingdom (Northern Ireland)<\/strong><\/p>\n\n\n\n<p>Almirall, SA, Tel: +353 (0) 1431 9836<\/p>\n\n\n\n<p><strong>Iceland<\/strong><\/p>\n\n\n\n<p>Visitor hf., Phone: +354 535 70 00<\/p>\n\n\n\n<p><strong>Italy<\/strong><\/p>\n\n\n\n<p>Almirall SpA, Tel.: +39 02 346181<\/p>\n\n\n\n<p><strong>The Netherlands<\/strong><\/p>\n\n\n\n<p>Almirall BV, Tel: +31 (0)307991155<\/p>\n\n\n\n<p><strong>Austria<\/strong><\/p>\n\n\n\n<p>Almirall GmbH, Tel.: +43 (0)1\/595 39 60<\/p>\n\n\n\n<p><strong>Polish<\/strong><\/p>\n\n\n\n<p>Almirall Sp.z oo, Tel.: +48 22 330 02 57<\/p>\n\n\n\n<p><strong>Portugal<\/strong><\/p>\n\n\n\n<p>Almirall &#8211; Produtos Farmac\u00eauticos, Lda., Tel.: +351 21 415 57 50<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Skilarence is a treatment used to treat plaque psoriasis, which causes swollen, red, and irritated skin patches with scaly spots.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24339,24343,24342,24344,24348,24347,24341,24340,24345,24346],"class_list":["post-23270","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-dimethyl-fumarate","tag-dimethyl-fumarate-side-effects","tag-dimethyl-fumarate-tablet","tag-skilarence","tag-skilarence-side-effects","tag-skilarence-tablet","tag-what-dimethyl-fumarate-is-used-for","tag-what-is-dimethyl-fumarate","tag-what-is-skilarence","tag-what-skilarence-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23270"}],"version-history":[{"count":61,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23270\/revisions"}],"predecessor-version":[{"id":49914,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23270\/revisions\/49914"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}