{"id":23237,"date":"2022-07-25T12:01:03","date_gmt":"2022-07-25T12:01:03","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23237"},"modified":"2022-07-26T06:16:45","modified_gmt":"2022-07-26T06:16:45","slug":"sive-extra","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sive-extra\/","title":{"rendered":"Sive\u00a0Extra\u00a0&#8211; Tedizolid phosphate uses, dose and side effects"},"content":{"rendered":"\n<p> tedizolid phosphate200 mg\u00a0film-coated tablets<br>tedizolid phosphate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sivextro is and what it is used for<\/h2>\n\n\n\n<p>Sivextro is an&nbsp;antibiotic&nbsp;that contains the active substance tedizolid phosphate.&nbsp;It belongs to a group of medicines called &#8220;oxazolidinones&#8221;.<\/p>\n\n\n\n<p>It is used to treat adults and adolescents from 12 years of age with&nbsp;infection&nbsp;in the skin and&nbsp;tissues&nbsp;under the skin.<\/p>\n\n\n\n<p>It works by stopping the growth of certain bacteria that can cause serious\u00a0infections.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Sivextro<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Sivextro<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to tedizolid phosphate or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Your doctor has decided that Sivextro is suitable for treating your\u00a0infection.<\/p>\n\n\n\n<p>Talk to your doctor or nurse before taking Sivextro if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have diarrhea, or have had diarrhea while (or up to 2 months after) you have taken\u00a0antibiotics in\u00a0the past.<\/li><li>if you are allergic to other medicines that belong to the &#8220;oxazolidinones&#8221; group, e.g.\u00a0linezolid, cycloserine).<\/li><li>if you have a history of bleeding or easy bruising (which may be a sign of a low number of\u00a0platelets, the small cells that help the blood to clot).<\/li><li>if you have kidney problems.<\/li><li>if you are taking certain medicines to treat depression called tricyclics, SSRIs (selective serotonin reuptake inhibitors), or\u00a0MAOIs\u00a0(monoamine oxidase inhibitors). See Other medicines and Sivextro for examples.<\/li><li>if you take certain medicines to treat\u00a0migraines\u00a0called &#8216;triptans&#8217;.\u00a0See Other medicines and Sivextro for examples.<\/li><\/ul>\n\n\n\n<p>Ask your doctor or pharmacist if you are not sure if you are taking any of these medicines.<\/p>\n\n\n\n<p>Diarrhea<\/p>\n\n\n\n<p>Contact your doctor immediately if you develop diarrhea during or after treatment.&nbsp;Do not take any medicine to treat diarrhea without first consulting your doctor.<\/p>\n\n\n\n<p>Resistance&nbsp;to&nbsp;antibiotics<\/p>\n\n\n\n<p>Bacteria can become resistant to antibiotic treatment over time.\u00a0This means that\u00a0antibiotics\u00a0cannot stop the growth of bacteria and treat your infection.\u00a0Your doctor will decide whether you should receive Sivextro to treat your\u00a0infection.<\/p>\n\n\n\n<p>Possible&nbsp;side effects&nbsp;are<\/p>\n\n\n\n<p>Some&nbsp;side effects&nbsp;have been seen with Sivextro or another member of the oxazolidinone class when&nbsp;administered&nbsp;for a period longer than that recommended for Sivextro.&nbsp;Tell your doctor immediately if you experience any of the following while taking Sivextro:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a low\u00a0white blood cell count<\/li><li>anemia\u00a0(low\u00a0red blood cell count\u00a0)<\/li><li>bleeds or bruises easily<\/li><li>loss of sensation in the hands and feet (for example, numbness, tingling\/tingling, or severe pain)<\/li><li>vision problems, e.g.\u00a0blurred vision, altered color vision, difficulty seeing details, or if the\u00a0field\u00a0of vision becomes restricted.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>This medicine should not be used in children under 12 years of age as it has not been sufficiently studied in this patient group.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sivextro<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines.\u00a0You must tell your doctor if you are also taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>amitriptyline,\u00a0citalopram, clomipramine, dosulepin, doxepin,\u00a0fluoxetine, fluvoxamine, imipramine, isocarboxazid, lofepramine, moclobemide,\u00a0paroxetine, phenelzine,\u00a0selegiline, and\u00a0sertraline\u00a0(used to treat depression)<\/li><li>sumatriptan, zolmitriptan (used to treat\u00a0migraine\u00a0)<\/li><li>imatinib, lapatinib (used to treat cancer)<\/li><li>methotrexate (used to treat cancer,\u00a0rheumatoid arthritis,\u00a0or\u00a0psoriasis\u00a0)<\/li><li>sulfasalazine (used to treat inflammatory bowel disease)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/topotecan-ebewe\/\">topotecan<\/a> (used to treat cancer)<\/li><li>statins such as pitavastatin, and rosuvastatin (used to lower blood cholesterol levels)<\/li><\/ul>\n\n\n\n<p>Sivextro can interfere with the effects of these medicines.&nbsp;Your doctor can explain in more detail.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>It is unknown if Sivextro is excreted in breast milk.&nbsp;Consult your doctor before breastfeeding your baby.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Avoid driving or using machines if you feel dizzy or tired after taking this medicine.<a><\/a><br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Sivextro<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one 200 mg tablet once daily for 6 days.&nbsp;The tablets must be swallowed whole and can be taken with or without food or drink.<\/p>\n\n\n\n<p>Talk to your doctor if you do not feel better or if you feel worse after 6 days.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Sivextro<\/h2>\n\n\n\n<p>Contact a doctor, pharmacist, or the nearest emergency department as soon as possible if you have taken more tablets than you should, and take the medicine with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Sivextro<\/h2>\n\n\n\n<p>If you forget to take your medicine, take a\u00a0dose\u00a0as soon as possible up to 8 hours before the next scheduled\u00a0dose.\u00a0If it is less than 8 hours until the next\u00a0dose, wait until it is time for the next scheduled\u00a0dose.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.\u00a0If you are unsure, consult a pharmacist.<\/p>\n\n\n\n<p>You must take all 6 tablets to complete the treatment course, even if you have missed a\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Sivextro<\/h2>\n\n\n\n<p>If you stop taking Sivextro without first consulting your doctor, your symptoms may worsen.&nbsp;Talk to your doctor or pharmacist before you stop taking the medicine.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact your doctor immediately<\/strong>&nbsp;if you develop diarrhea during or after treatment.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;can be:<\/strong><\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea<\/li><li>Vomiting<\/li><li>Headache<\/li><li>Itching&nbsp;all over the body<\/li><li>Fatigue<\/li><li>Dizziness<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fungal infections of the skin, mouth, and vagina (oral\/vaginal thrush)<\/li><li>Itching\u00a0(including\u00a0itching\u00a0due to\u00a0an allergic reaction\u00a0), hair loss,\u00a0acne, red and\/or itchy rash or\u00a0hives, profuse sweating<\/li><li>Decreased or lost sensitivity in the skin, tingling\/stinging sensation in the skin<\/li><li>Flushing or\u00a0redness\u00a0of the face, neck, or upper chest<\/li><li>An abscess\u00a0(swollen, fluid-filled lump)<\/li><li>Infection,\u00a0inflammation,\u00a0or\u00a0itching\u00a0in the vagina<\/li><li>Restlessness, irritability, shaking, or tremors<\/li><li>Respiratory tract infection (sinuses, pharynx, and chest)<\/li><li>Dryness of the nose, congestion in the chest, cough<\/li><li>Drowsiness, abnormal sleep patterns, difficulty sleeping, nightmares (unpleasant\/disturbing dreams)<\/li><li>Dry mouth, constipation, indigestion, stomach (abdominal) pain\/discomfort, retching, belching, bright red blood in the stool<\/li><li>Reflux disease\u00a0(heartburn, pain, or difficulty swallowing), gas in the stomach<\/li><li>Joint pain, muscle cramps, back pain, neck pain, pain\/discomfort in arms and legs, decreased grip strength<\/li><li>Blurry vision, &#8220;spots&#8221; (small dots that float around in the field of\u00a0vision,\u00a0etc.)<\/li><li>Swollen or enlarged\u00a0lymph nodes<\/li><li>Allergic reaction<\/li><li>Dehydration<\/li><li>Poor control of\u00a0diabetes<\/li><li>Abnormal taste experience<\/li><li>Slow heartbeat<\/li><li>Fever<\/li><li>Swollen ankles and\/or feet<\/li><li>Urine smells abnormal, and abnormal blood tests<\/li><\/ul>\n\n\n\n<p>Frequency not known (cannot be estimated from available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bleeding and bruising more easily (due to a low number of\u00a0platelets, the small cells that help the blood clot)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How Sivextro should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton or blister label after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tedizolid phosphate.\u00a0One film-coated tablet contains 200 mg of tedizolid phosphate.<\/li><li>Other ingredients are microcrystalline cellulose, mannitol, povidone, crospovidone, and magnesium stearate inside the tablet core.\u00a0The film coating of the tablet contains polyvinyl alcohol, titanium dioxide (E171), macrogol, talc, and yellow iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Sivextro is an oval, yellow, film-coated tablet marked with &#8216;TZD&#8217; on one side and &#8216;200&#8217; on the other side.<\/p>\n\n\n\n<p>It is supplied as 6 \u00d7 1 tablets in perforated unit dose blisters.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Merck Sharp &amp; Dohme BV<\/p>\n\n\n\n<p>Waarderweg 39<\/p>\n\n\n\n<p>2031 BN Haarlem<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong>MSD BelgiumTel\/Tel: +32(0)27766211dpoc_belux@merck.com<\/td><td><strong>Lithuania<\/strong>UAB Merck Sharp &amp; DohmeTel.: +370 5 278 02 47msd_lietuva@merck.com<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>\u041c\u0435\u0440\u043a \u0428\u0430\u0440\u043f \u0438 \u0414\u043e\u043c \u0411\u0443\u043b\u0433\u0430\u0440\u0438\u044f \u0415\u041e\u041e\u0414Tel.: +359 2 819 3737info-msdbg@merck.com<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>MSD BelgiumTel\/Tel: +32(0)27766211dpoc_belux@merck.com<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Merck Sharp &amp; Dohme s.r.oTel.: +420 233 010 111dpoc_czechslovak@merck.com<\/td><td><strong>Magyarorsz\u00e1g<\/strong>MSD Pharma Hungary Kft.Tel.: +361 888 53 00hungary_msd@merck.com<\/td><\/tr><tr><td><strong>Denmark<\/strong>MSD Danmark ApSPhone: +45 4482 4000dkmail@merck.com<\/td><td><strong>Malta<\/strong>Merck Sharp &amp; Dohme Cyprus LimitedPhone: 8007 4433 (+356 99917558)malta_info@merck.com<\/td><\/tr><tr><td><strong>Deutschland<\/strong>MSD Sharp &amp; Dohme GmbHPhone: 0800 673 673 673 (+49 (0) 89 4561 0)e-mail@msd.de<\/td><td><strong>The Netherlands<\/strong>Merck Sharp &amp; Dohme BVPhone: 0800 9999000 (+31 23 5153153)medicalinfo.nl@merck.com<\/td><\/tr><tr><td><strong>Estonia<\/strong>Merck Sharp &amp; Dohme O\u00dcTel.: +372 6144 200msdeesti@merck.com<\/td><td><strong>Norway<\/strong>MSD (Norway) iPhone: +47 32 20 73 00msdnorge@msd.no<\/td><\/tr><tr><td><strong>Greece<\/strong>MSD \u0391.\u03a6.\u0392.\u0395.\u0395.Tel: +30 210 98 97 300dpoc_greece@merck.com<\/td><td><strong>Austria<\/strong>Merck Sharp &amp; Dohme Ges.mbHPhone: +43 (0) 1 26 044msd-medizin@merck.com<\/td><\/tr><tr><td><strong>Spain<\/strong>Merck Sharp &amp; Dohme de Espa\u00f1a, SAPhone: +34 91 321 06 00msd_info@merck.com<\/td><td><strong>Polish<\/strong>MSD Polska Sp. z o. oTel.: +48 22 549 51 00msdpolska@merck.com<\/td><\/tr><tr><td><strong>France<\/strong>MSD FranceTel: + 33 (0) 1 80 46 40 40<\/td><td><strong>Portugal<\/strong>Merck Sharp &amp; Dohme, LdaPhone: +351 21 4465700inform_pt@merck.com<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Merck Sharp &amp; Dohme dooPhone: + 385 1 6611 333croatia_info@merck.com<\/td><td><strong>Romania<\/strong>Merck Sharp &amp; Dohme Romania SRLPhone: +40 21 529 29 00msdromania@merck.com<\/td><\/tr><tr><td><strong>Ireland<\/strong>Merck Sharp &amp; Dohme Ireland (&nbsp;Human&nbsp;Health) LimitedPhone: +353 (0)1 299 8700medinfo_ireland@merck.com<\/td><td><strong>Slovenija<\/strong>Merck Sharp &amp; Dohme, inovativna svlad\u00edva dooPhone: + 386 1 5204 201msd.slovenia@merck.com<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovenian Republic<\/strong>Merck Sharp &amp; Dohme, s.r.oTel.: +421 2 58282010dpoc_czechslovak@merck.com<\/td><\/tr><tr><td><strong>Italy<\/strong>MSD Italia SrlPhone: +39 06 361911medicalinformation.it@merck.com<\/td><td><strong>Finland\/Finland<\/strong>MSD Finland OyTel: +358 (0) 9 804650info@msd.fi<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Merck Sharp &amp; Dohme Cyprus LimitedTel: 800 00 673 (+357 22866700)cyprus_info@merck.com<\/td><td><strong>Sweden<\/strong>Merck Sharp &amp; Dohme (Sweden) ABPhone: +46 77 5700488medicalinfo@merck.com<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA Merck Sharp &amp; Dohme LatvijaPhone: +371 67364224msd_lv@merck.com.<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Merck Sharp &amp; Dohme Ireland (&nbsp;Human&nbsp;Health) LimitedPhone: +353 (0)1 2998700medinfoNI@msd.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Sivextro is an\u00a0antibiotic\u00a0that contains the active substance tedizolid phosphate.\u00a0It belongs to a group of medicines called &#8220;oxazolidinones&#8221;.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24245,24249,24248,24240,24244,24243,24246,24241,24247,24242],"class_list":["post-23237","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-sive-extra","tag-sive-extra-side-effects","tag-sive-extra-tablet","tag-tedizolid-phosphate","tag-tedizolid-phosphate-side-effects","tag-tedizolid-phosphate-tablet","tag-what-is-sive-extra","tag-what-is-tedizolid-phosphate","tag-what-sive-extra-is-used-for","tag-what-tedizolid-phosphate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23237","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23237"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23237\/revisions"}],"predecessor-version":[{"id":23263,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23237\/revisions\/23263"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23237"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23237"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23237"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}