{"id":23234,"date":"2022-07-25T11:53:36","date_gmt":"2022-07-25T11:53:36","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23234"},"modified":"2022-07-26T06:16:51","modified_gmt":"2022-07-26T06:16:51","slug":"sitagliptin-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sitagliptin-accord\/","title":{"rendered":"Sitagliptin Accord &#8211; Sitagliptin uses, dose and side effects"},"content":{"rendered":"\n<p>25 mg, 50 mg, and 100 mg\u00a0film-coated tablets<br>sitagliptin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sitagliptin Accord is and what it is used for<\/h2>\n\n\n\n<p>Sitagliptin Accord contains the active substance sitagliptin, which belongs to a group of medicines that lower blood sugar levels in adult patients with&nbsp;diabetes mellitus&nbsp;type 2. These are called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors).<\/p>\n\n\n\n<p>This medicine helps to increase the insulin levels produced after a meal and reduces the amount of sugar that is formed in the body.<\/p>\n\n\n\n<p>Your doctor has prescribed this medicine to help lower your blood sugar, which is too high due to your type 2\u00a0diabetes.\u00a0This medicine can be used alone or in combination with certain other blood sugar-lowering medicines (\u00a0insulin,\u00a0metformin, sulphonylureas, or glitazones) that you may already be taking for your\u00a0diabetes\u00a0and together with a diet and exercise program.<\/p>\n\n\n\n<p>What is type 2\u00a0diabetes?<\/p>\n\n\n\n<p>Type 2\u00a0diabetes\u00a0is a condition in which your body does not make enough\u00a0insulin\u00a0and the\u00a0insulin\u00a0the body produces does not work as well as it should.\u00a0Your body can also make too much sugar.\u00a0When this happens, sugar (\u00a0glucose\u00a0) accumulates in the blood.\u00a0This can lead to serious medical problems such as heart disease, kidney disease, blindness, and amputation.<br><br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Sitagliptin Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Sitagliptin Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sitagliptin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Cases of&nbsp;inflammation&nbsp;of the pancreas (&nbsp;pancreatitis&nbsp;) have been reported in patients receiving Sitagliptin Accord (see section 4).<\/p>\n\n\n\n<p>If you get blisters on your skin, it could be a sign of a condition called bullous\u00a0pemphigoid.\u00a0Your doctor may tell you to stop taking Sitagliptin Accord.<\/p>\n\n\n\n<p>Tell your doctor if you have or have had:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a disease of the pancreas (such as\u00a0pancreatitis\u00a0)<\/li><li>gallstones, alcohol dependence, or very high levels of\u00a0triglycerides\u00a0(a type of fat) in the blood.\u00a0These medical conditions may increase the risk of\u00a0developing pancreatitis\u00a0(see section 4).<\/li><li>type 1\u2011\u00a0diabetes<\/li><li>increased levels of ketones in the blood and urine (diabetic ketoacidosis; a complication of\u00a0diabetes\u00a0with high blood sugar, rapid weight loss, nausea, or vomiting)<\/li><li>any past or present problems with the kidneys<\/li><li>an\u00a0allergic reaction\u00a0to Sitagliptin Accord (see section 4).<\/li><\/ul>\n\n\n\n<p>This medicine does not work when blood sugar is low and is therefore unlikely to cause too low blood sugar.\u00a0However, when this drug is used in combination with sulfonylurea or\u00a0insulin, low blood sugar (\u00a0hypoglycemia\u00a0) may occur.\u00a0Your doctor can then reduce the\u00a0dose\u00a0of one of your sulfonylurea or your\u00a0insulin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Children and adolescents under the age of 18 should not use this medicine.&nbsp;It is not effective in children and adolescents between 10 and 17 years of age.&nbsp;It is not known if this medicine is safe and effective when used in children and adolescents under 10 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sitagliptin Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are taking&nbsp;digoxin&nbsp;(a medicine used to treat irregular heart rhythms and other heart problems).&nbsp;The level of&nbsp;digoxin&nbsp;in the blood may need to be checked if it is taken together with Sitagliptin Accord.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>You should not use this medicine during pregnancy.<\/p>\n\n\n\n<p>It is not known whether this medicine passes into breast milk.\u00a0You should not use this medicine if you are breastfeeding or plan to breastfeed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>This medicine has no or negligible effect on the ability to drive and use machines.&nbsp;However, dizziness and drowsiness have been reported, which may affect your ability to drive and use machines.<\/p>\n\n\n\n<p>Concomitant use of this medicine with medicines called sulphonylureas or with\u00a0insulin\u00a0may cause\u00a0hypoglycemia, which may affect your ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Sitagliptin Accord contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8216;sodium-free&#8217;.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Sitagliptin Accord<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The usual recommended\u00a0dose\u00a0is:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a film-coated tablet of 100 mg<\/li><li>once daily<\/li><li>through the mouth.<\/li><\/ul>\n\n\n\n<p>If you have kidney problems, your doctor may prescribe you a lower&nbsp;dose&nbsp;(such as 25 mg or 50 mg).<\/p>\n\n\n\n<p>You can take this medicine with or without food and drink.<\/p>\n\n\n\n<p>Your doctor may prescribe this medicine alone or together with certain other medicines that lower blood sugar.<\/p>\n\n\n\n<p>Diet and exercise can help your body make better use of blood sugar.&nbsp;It is important to continue with the diet and exercise recommended by the doctor while you are taking Sitagliptin Accord.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Sitagliptin Accord<\/h2>\n\n\n\n<p>Contact your doctor immediately if you have taken more than the prescribed&nbsp;dose&nbsp;of one of these medicines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Sitagliptin Accord<\/h2>\n\n\n\n<p>If you have forgotten to take a\u00a0dose, take it as soon as you remember.\u00a0If you do not remember it until it is time for the next\u00a0dose, then do not take the missed\u00a0dose\u00a0and continue the usual dosing schedule.\u00a0Do not take a double\u00a0dose\u00a0of this medicine on the same day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Sitagliptin Accord<\/h2>\n\n\n\n<p>To keep your blood sugar under control, you should continue to take this medicine for as long as your doctor has prescribed the treatment.&nbsp;You should not stop taking the medicine without talking to your doctor first.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>STOP taking Sitagliptin Accord and contact your doctor immediately if you notice any of the following serious side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe and persistent pain in the abdomen (stomach) that may radiate to the back, with or without nausea and vomiting, as these may be signs of an inflamed&nbsp;pancreas&nbsp;(&nbsp;pancreatitis&nbsp;).<\/li><\/ul>\n\n\n\n<p>If you get a serious\u00a0allergic reaction\u00a0(frequency not known), such as rash, hives, skin blisters\/scaly skin, and swelling of the face, lips, tongue, and throat which may cause breathing or swallowing difficulties, stop taking this medicine and contact your doctor immediately.\u00a0Your doctor may\u00a0prescribe\u00a0one medicine to treat your allergic reaction and another medicine for your\u00a0diabetes.<\/p>\n\n\n\n<p>Some patients have experienced the following&nbsp;side effects&nbsp;when adding sitagliptin to metformin:<\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 people): low blood sugar, feeling sick, feeling sick, being sick<\/p>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people): stomach pain, diarrhea, constipation, drowsiness<\/p>\n\n\n\n<p>Some patients have experienced various types of stomach discomfort when starting combination therapy with sitagliptin and&nbsp;metformin&nbsp;together (reported frequency: common).<\/p>\n\n\n\n<p>Some patients have experienced the following\u00a0side effects\u00a0when taking sitagliptin in combination with sulphonylurea and metformin:<\/p>\n\n\n\n<p>Very common (may affect more than 1 in 10 people): low blood sugar<\/p>\n\n\n\n<p>Common: constipation<\/p>\n\n\n\n<p>Some patients have experienced the following&nbsp;side effects&nbsp;when taking sitagliptin and pioglitazone:<\/p>\n\n\n\n<p>Common: weather tension, swollen hands, and legs<\/p>\n\n\n\n<p>Some patients have experienced the following&nbsp;side effects&nbsp;when taking sitagliptin in combination with pioglitazone and metformin:<\/p>\n\n\n\n<p>Common: swollen hands and legs<\/p>\n\n\n\n<p>Some patients have experienced the following&nbsp;side effects&nbsp;when taking sitagliptin in combination with&nbsp;insulin&nbsp;(with or without&nbsp;metformin&nbsp;):<\/p>\n\n\n\n<p>Common:&nbsp;influenza<\/p>\n\n\n\n<p>Uncommon:&nbsp;dry mouth<\/p>\n\n\n\n<p>Some patients have experienced the following\u00a0side effects\u00a0when taking sitagliptin alone in\u00a0clinical trials\u00a0or during post-approval follow-up when using sitagliptin alone and\/or in combination with other diabetes medicines:<\/p>\n\n\n\n<p>Common: low blood sugar, headache, upper respiratory tract infection, stuffy or runny nose and sore throat,\u00a0osteoarthritis, pain in arms or legs.<\/p>\n\n\n\n<p>Uncommon: dizziness, constipation,&nbsp;itching<\/p>\n\n\n\n<p>Rare: decreased number of&nbsp;blood platelets<\/p>\n\n\n\n<p>Not known frequency: kidney problems (which sometimes require&nbsp;dialysis&nbsp;), vomiting, joint pain, muscle pain, back pain, interstitial lung disease, bullous&nbsp;pemphigoid&nbsp;(a kind of blistering of the skin).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sitagliptin Accord<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the blister and carton after &#8220;EXP&#8221; and &#8220;Exp. date&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is sitagliptin.<\/p>\n\n\n\n<p><em>Sitagliptin Accord 25 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet (tablet) contains sitagliptin hydrochloride monohydrate equivalent to 25 mg of sitagliptin.<\/p>\n\n\n\n<p><em>Sitagliptin Accord 50 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet (tablet) contains sitagliptin hydrochloride monohydrate equivalent to 50 mg sitagliptin.<\/p>\n\n\n\n<p><em>Sitagliptin Accord 100 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet (tablet) contains sitagliptin hydrochloride monohydrate equivalent to 100 mg of sitagliptin.<\/p>\n\n\n\n<p>Other ingredients are: In the tablet core: microcrystalline cellulose (E460), calcium hydrogen phosphate, croscarmellose sodium (E468), and magnesium stearate (E470b).\u00a0The film coating of the tablet contains poly(vinyl alcohol), macrogol 3350, talc (E553b), titanium dioxide (E171), red iron oxide (E172), and yellow iron oxide (E172).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p><em><u>Sitagliptin Accord 25 mg film-coated tablets:<\/u><\/em>\u00a0A pink, round, film-coated tablet with a smooth edge, debossed with \u201cS3\u201d on one side and plain on the other side.\u00a0Diameter 6 mm to 6.40 mm.<\/p>\n\n\n\n<p><em><u>Sitagliptin Accord 50 mg film-coated tablets:<\/u><\/em>\u00a0Light beige, round, film-coated tablet with a beveled edge, debossed with \u201cS4\u201d on one side and plain on the other side.\u00a0Diameter 8 mm to 8.40 mm.<\/p>\n\n\n\n<p><em><u>Sitagliptin Accord 100 mg film-coated tablets:<\/u><\/em>\u00a0Beige, round, film-coated tablets with a beveled edge, debossed with \u201cS7\u201d on one side and plain on the other side.\u00a0Diameter 10 mm to 10.40 mm.<\/p>\n\n\n\n<p>PVC\/PE\/PVDC aluminum blisters.&nbsp;Packs of 28, 30, 56, 98 or 100 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Accord Healthcare SLU<\/p>\n\n\n\n<p>World Trade Center, Moll de Barcelona, \u200b\u200bs\/n,<\/p>\n\n\n\n<p>Edifici Est, 6&nbsp;<sup>a<\/sup>&nbsp;Planta,<\/p>\n\n\n\n<p>08039 Barcelona, \u200b\u200bSpain<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.&nbsp;Zoo<\/p>\n\n\n\n<p>ul.Lutomierska 50,<\/p>\n\n\n\n<p>95-200, Pabianice, Poland<\/p>\n\n\n\n<p>Paradox Healthcare Limited<\/p>\n\n\n\n<p>KW20A Kordin Industrial Park,<\/p>\n\n\n\n<p>Paola PLA 3000, Malta<\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200,<\/p>\n\n\n\n<p>3526 KV Utrecht, The Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sitagliptin Accord contains the active substance sitagliptin, which belongs to a group of medicines that lower blood sugar levels in adult patients with\u00a0diabetes mellitus\u00a0type 2. These are called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[14947,24250,24253,24254,14951,14950,14948,24251,24252,14949],"class_list":["post-23234","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-sitagliptin","tag-sitagliptin-accord","tag-sitagliptin-accord-side-effects","tag-sitagliptin-accord-tablet","tag-sitagliptin-side-effects","tag-sitagliptin-tablet","tag-what-is-sitagliptin","tag-what-is-sitagliptin-accord","tag-what-sitagliptin-accord-is-used-for","tag-what-sitagliptin-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23234"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23234\/revisions"}],"predecessor-version":[{"id":23264,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23234\/revisions\/23264"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23234"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}