{"id":23224,"date":"2022-07-25T11:46:41","date_gmt":"2022-07-25T11:46:41","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23224"},"modified":"2022-07-26T06:17:16","modified_gmt":"2022-07-26T06:17:16","slug":"singulair","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/singulair\/","title":{"rendered":"Singulair &#8211; Montelukast uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg&nbsp;film-coated tablets<br>montelukast<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Singulair is and what it is used for<\/h2>\n\n\n\n<p><strong>What Singulair is<\/strong><\/p>\n\n\n\n<p>Singulair is a leukotriene receptor antagonist that blocks substances called\u00a0leukotrienes.<\/p>\n\n\n\n<p><strong>How Singulair works<\/strong><\/p>\n\n\n\n<p>Leukotriene\u00a0er causes constriction and swelling of the airways in the lungs and also causes allergic symptoms.\u00a0By blocking the\u00a0leukotrienes, Singulair improves the symptoms of\u00a0asthma, helps control\u00a0asthma,\u00a0and improves the symptoms of seasonal\u00a0allergies\u00a0(so-called hay fever or seasonal allergic\u00a0rhinitis\u00a0).<\/p>\n\n\n\n<p><strong>When to use Singulair<\/strong><\/p>\n\n\n\n<p>Your doctor has prescribed Singulair to treat&nbsp;asthma&nbsp;and thus prevent asthma symptoms during the day and night.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Singulair is used for the treatment of adults and adolescents, 15 years of age and older, who have not been adequately controlled with previous asthma medication and therefore need additional treatment.<\/li><li>Singulair also prevents constriction of the airways associated with physical exertion.<\/li><li>Singulair can also be used for seasonal allergic\u00a0rhinitis\u00a0in those patients where Singulair is used to treat\u00a0asthma.<\/li><\/ul>\n\n\n\n<p>Depending on your symptoms and the severity of your\u00a0asthma, your doctor will decide how Singulair should be used.<\/p>\n\n\n\n<p><strong>What is\u00a0asthma?<\/strong><br>Asthma\u00a0is a\u00a0chronic\u00a0disease.<\/p>\n\n\n\n<p>Asthma&nbsp;includes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty breathing due to constriction of the airways.\u00a0This constriction of the airways worsens and improves depending on different conditions.<\/li><li>Sensitive airways that react to different things such as cigarette smoke, pollen, cold air, or exertion.<\/li><li>Swelling (\u00a0inflammation\u00a0) of the mucous membranes of the respiratory tract.<\/li><\/ul>\n\n\n\n<p>Symptoms of\u00a0asthma\u00a0include coughing, wheezing, and chest tightness.<\/p>\n\n\n\n<p><strong>What is a <\/strong>seasonal\u00a0allergy?<br>Seasonal\u00a0allergy\u00a0(also called hay fever or seasonal allergic\u00a0rhinitis\u00a0) is an\u00a0allergic reaction\u00a0that is often caused by airborne pollen from trees, grass, or weeds.\u00a0The symptoms of seasonal\u00a0allergy\u00a0are characterized by;\u00a0a stuffy, runny, and itchy nose;\u00a0sneezing;\u00a0watery, swollen, red, and itchy eyes.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Singulair<\/h2>\n\n\n\n<p>Tell your doctor about any medical or allergy problems you have or have had.<\/p>\n\n\n\n<p><strong>Do not take Singulair<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to montelukast or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Singulair.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If asthma symptoms or breathing worsen, contact your doctor immediately.<\/li><li>Singulair is not intended for the treatment of acute asthma attacks.\u00a0If an attack occurs, follow the instructions given by the doctor for this situation.\u00a0Always carry your inhaled bronchodilator asthma medicine with you for acute asthma attacks.<\/li><li>You or your child must take any other asthma medicines prescribed by the doctor.\u00a0Singulair is not intended to replace other asthma medicines prescribed by the doctor for concomitant treatment.<\/li><li>During treatment with asthma medication, you should know that if you get a combination of different symptoms, such as\u00a0flu-like symptoms, tingling or numbness in the arms or legs, worsening respiratory symptoms, and\/or skin rashes, a doctor should be contacted.<\/li><li>If you know that your asthma is worsened by\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/treo-comp\/\">aspirin<\/a>\u00a0or other anti-inflammatory\u00a0agents (so-called\u00a0NSAIDs\u00a0), then do not use these drugs.<\/li><\/ul>\n\n\n\n<p>Patients should be aware that various neuropsychiatric events (eg, behavior and mood-related changes) have been reported in adults, adolescents, and children with Singulair (see section 4).&nbsp;If you develop such symptoms while using Singulair, you should contact your doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children younger than 15 years of age.<\/p>\n\n\n\n<p>There are other formulations of this medicine available for children and adolescents under the age of 18 that are based on age group.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Singulair<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines, even those without a prescription.<\/p>\n\n\n\n<p>Some medicines can affect how Singulair works and Singulair can affect how other medicines work.<\/p>\n\n\n\n<p>Tell your doctor if you are using the following medications before you start taking Singulair:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>phenobarbital (&nbsp;antiepileptic&nbsp;)<\/li><li>phenytoin&nbsp;(medicine for&nbsp;epilepsy&nbsp;)<\/li><li>rifampicin (medicine against&nbsp;tuberculosis&nbsp;and other&nbsp;infections&nbsp;)<\/li><li>gemfibrozil (medicine for high blood fat levels)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Singulair with food and drink<\/h2>\n\n\n\n<p>Singulair 10 mg film-coated tablets can be taken with or without food.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using Singulair.<\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>Your doctor will decide if you can take Singulair during this time.<\/p>\n\n\n\n<p>Breastfeeding<br>It is unknown whether Singulair passes into breast milk.&nbsp;Therefore, consult a doctor before using Singulair during breastfeeding or planned breastfeeding.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Singulair is not expected to affect your ability to drive or operate machinery.&nbsp;However, individual reactions to drugs can vary.&nbsp;However, dizziness and drowsiness have been reported which may affect some patients&#8217; ability to drive or operate machinery.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Singulair 10 mg film-coated tablets contain lactose and sodium<\/h2>\n\n\n\n<p>If you have an intolerance to some sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8220;sodium-free&#8221;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Singulair<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take only one Singulair tablet a day as directed by your doctor.<\/li><li>You must continue to take Singulair both during symptom-free periods and during an\u00a0acute\u00a0asthma attack.<\/li><\/ul>\n\n\n\n<p><strong>Adults and adolescents, 15 years and older<\/strong><br>The recommended&nbsp;dose&nbsp;is one 10 mg tablet taken once daily in the evening.<\/p>\n\n\n\n<p>Singulair should not be used with any other product that contains the same active ingredient, montelukast.<\/p>\n\n\n\n<p>This medicine should be taken by mouth.<\/p>\n\n\n\n<p>Singulair 10 mg can be taken with or without food.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Singulair<\/h2>\n\n\n\n<p>Contact a doctor immediately for advice.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>In the majority of the reports that exist of overdose, no\u00a0side effects\u00a0have been reported.\u00a0The most common symptoms reported in overdose in adults and children included abdominal pain, drowsiness, thirst, headache, vomiting, and hyperactivity.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Singulair<\/h2>\n\n\n\n<p>Try to take Singulair as\u00a0prescribed.\u00a0If you have missed a\u00a0dose, then return to the usual schedule of one tablet a day.<\/p>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Singulair<\/h2>\n\n\n\n<p>Singulair can only treat your&nbsp;asthma&nbsp;if you keep taking it.<\/p>\n\n\n\n<p>It is important to keep taking Singulair as long as your doctor prescribes it.\u00a0It helps you control your\u00a0asthma.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>In\u00a0clinical studies\u00a0with Singulair 10 mg film-coated tablets, the most commonly reported\u00a0side effects\u00a0(which may affect up to 1 in 10 users) where a probable relationship exists were:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stomach ache<\/li><li>headache<\/li><\/ul>\n\n\n\n<p>These were usually mild and occurred more often in patients treated with Singulair than with\u00a0a placebo\u00a0(a\u00a0pill\u00a0that does not contain any medicine).<\/p>\n\n\n\n<p><strong>Serious&nbsp;<\/strong><strong>side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Talk to your doctor immediately<\/strong>&nbsp;if you notice any of the following&nbsp;side effects&nbsp;which may be serious and may require&nbsp;urgent&nbsp;medical treatment.<\/p>\n\n\n\n<p>Uncommon: may affect up to 1 in 100 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions including swelling of the face, lips, tongue, and\/or throat, which may cause breathing or swallowing difficulties<\/li><li>behavioral and mood changes: anxiety\/agitation including aggressive behavior or hostility, depression<\/li><li>convulsions<\/li><\/ul>\n\n\n\n<p>Rare: may affect up to 1 in 1,000 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased tendency to bleed<\/li><li>tremors<\/li><li>palpitation<\/li><\/ul>\n\n\n\n<p>Very rare: may affect up to 1 in 10,000 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>combination of symptoms, such as\u00a0flu-like symptoms, tingling or numbness in the arms and legs, worsening respiratory symptoms, and\/or skin rash (Churg-Strauss syndrome) (see section 2)<\/li><li>decreased number of\u00a0platelets<\/li><li>behavioral and mood changes: hallucinations, disorientation, suicidal thoughts and actions<\/li><li>swelling (\u00a0inflammation\u00a0) in the lungs<\/li><li>serious skin reactions (erythema multiforme) which may appear without warning<\/li><li>inflammation of the liver (\u00a0hepatitis\u00a0)<\/li><\/ul>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0were reported during the time the medicine has been on the market<\/strong><\/p>\n\n\n\n<p>Very common: may affect more than 1 in 10 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>upper respiratory tract infection<\/li><\/ul>\n\n\n\n<p>Common: may affect up to 1 in 10 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea, nausea, vomiting<\/li><li>rash<\/li><li>fever<\/li><li>elevated liver enzymes<\/li><\/ul>\n\n\n\n<p>Uncommon: may affect up to 1 in 100 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>behavioral and mood changes: altered dream patterns including nightmares, insomnia, sleepwalking, irritability, anxiety, restlessness<\/li><li>dizziness, drowsiness, numbness, and tingling<\/li><li>nosebleed<\/li><li>dry mouth, indigestion<\/li><li>bruises,\u00a0itching,\u00a0hives<\/li><li>joint or muscle pain, muscle cramps<\/li><li>bedwetting in children<\/li><li>weakness\/fatigue, general malaise, swelling<\/li><\/ul>\n\n\n\n<p>Rare: may affect up to 1 in 1,000 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>behavioral and mood changes: impaired attention, impaired memory, involuntary muscle movements<\/li><\/ul>\n\n\n\n<p>Very rare: may affect up to 1 in 10,000 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>painful red bumps under the skin, preferably on the shins (erythema nodosum)<\/li><li>behavioral and mood changes: obsessive-compulsive symptoms, stuttering<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Singulair<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the blister and carton after EXP.&nbsp;The first two digits indicate the month and the last four digits indicate the year.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is montelukast.\u00a0One tablet contains montelukast sodium equivalent to 10 mg montelukast.<\/li><li>Other ingredients are\u00a0lactose monohydrate\u00a0(89.3 mg), microcrystalline cellulose, croscarmellose sodium, hydroxypropyl cellulose (E463), and magnesium stearate.<\/li><\/ul>\n\n\n\n<p>Film coating: Hypromellose, hydroxypropyl cellulose (E463), titanium dioxide (E171), red and yellow iron oxide (E172), and carnauba wax.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Singulair 10 mg tablet is beige, rounded square, film-coated, marked SINGULAIR on one side and MSD 117 on the other.<\/p>\n\n\n\n<p>Blisters in packs of: 7, 10, 14, 20, 28, 30, 50, 56, 84, 90, 98, 100, 140, 200 tablets.<\/p>\n\n\n\n<p>Blisters (single-dose) in packs of: 49&#215;1, 50&#215;1 and 56&#215;1 tablets<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>NV Organon<\/p>\n\n\n\n<p>Kloosterstraat 6<\/p>\n\n\n\n<p>5349 AB Us<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Merck Sharp &amp; Dohme BV<\/p>\n\n\n\n<p>PO Box 581<\/p>\n\n\n\n<p>2003 PC Haarlem<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Schering-Plough Labo NV<\/p>\n\n\n\n<p>Industriepark 30<\/p>\n\n\n\n<p>Heist-op-den-Berg, 2220<\/p>\n\n\n\n<p>Belgium<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Singulair is a leukotriene receptor antagonist that blocks substances called\u00a0leukotrienes\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24289,17881,24284,24288,17882],"class_list":["post-23224","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-singulair","tag-montelukast","tag-singulair","tag-singulair-tablet","tag-what-is-montelukast"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23224"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23224\/revisions"}],"predecessor-version":[{"id":23268,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23224\/revisions\/23268"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}