{"id":23181,"date":"2022-07-22T06:33:19","date_gmt":"2022-07-22T06:33:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23181"},"modified":"2022-07-25T11:38:30","modified_gmt":"2022-07-25T11:38:30","slug":"simvastatin-sandoz","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/simvastatin-sandoz\/","title":{"rendered":"Simvastatin Sandoz &#8211; Simvastatin uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg&nbsp;film-coated tablets<br>simvastatin<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Simvastatin Sandoz is and what it is used for<\/h2>\n\n\n\n<p>Simvastatin\u00a0Sandoz contains the active substance\u00a0simvastatin.\u00a0Simvastatin\u00a0Sandoz is a drug used to lower the levels of total cholesterol in the blood, the &#8220;bad&#8221;\u00a0cholesterol\u00a0(\u00a0LDL\u00a0cholesterol\u00a0), and blood fats, so-called\u00a0triglycerides.<\/p>\n\n\n\n<p>Simvastatin&nbsp;Sandoz also increases the levels of &#8220;good&#8221;&nbsp;cholesterol&nbsp;(&nbsp;HDL&nbsp;cholesterol&nbsp;).&nbsp;Simvastatin&nbsp;Sandoz belongs to a group of medicines called statins.<\/p>\n\n\n\n<p>Cholesterol\u00a0is one of several fats found in your blood.\u00a0Your total cholesterol consists mainly of\u00a0LDL\u00a0and\u00a0HDL\u00a0cholesterol.<\/p>\n\n\n\n<p>LDL\u00a0cholesterol\u00a0is often called the &#8220;bad&#8221;\u00a0cholesterol\u00a0because it causes fat storage in your artery walls and forms\u00a0plaque.\u00a0This plaque buildup can eventually lead to the narrowing of your\u00a0arteries.\u00a0This narrowing can reduce or block blood flow to important organs such as the heart and brain.\u00a0Blockage of blood flow can result in a heart attack or\u00a0stroke.<\/p>\n\n\n\n<p>HDL&nbsp;cholesterol&nbsp;is often called the &#8220;good&#8221;&nbsp;cholesterol&nbsp;because it helps prevent the &#8220;bad&#8221;&nbsp;cholesterol&nbsp;from being stored in the&nbsp;arteries&nbsp;and&nbsp;protects against heart disease.<\/p>\n\n\n\n<p>Triglycerides&nbsp;are another type of fat in the blood that can increase the risk of heart disease.<\/p>\n\n\n\n<p>You should continue with a cholesterol-lowering diet while you are taking this medicine.<\/p>\n\n\n\n<p>Simvastatin&nbsp;Sandoz is used as a supplement to your cholesterol-lowering diet if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>elevated blood cholesterol levels (primary\u00a0hypercholesterolemia\u00a0) or elevated blood fats (combined\u00a0hyperlipidemia\u00a0)<\/li><li>an inherited disease (\u00a0homozygous\u00a0familial\u00a0hypercholesterolemia\u00a0) that causes elevated cholesterol levels in the blood.\u00a0You can also receive other treatments.<\/li><li>coronary heart disease or if you are at high risk of developing coronary heart disease (because you have\u00a0diabetes, had a previous\u00a0stroke,\u00a0or had another vascular disease).\u00a0Treatment with\u00a0Simvastatin\u00a0Sandoz can lead to prolonged survival by reducing the risk of heart disease, regardless of the amount of cholesterol in your blood.<\/li><\/ul>\n\n\n\n<p>In most people, high\u00a0cholesterol\u00a0does not cause immediate symptoms.\u00a0Your doctor can measure your cholesterol level with a simple blood test.\u00a0Visit your doctor regularly, monitor your cholesterol levels, and discuss your goals with your doctor.\u00a0Simvastatin\u00a0found in<\/p>\n\n\n\n<p>Simvastatin\u00a0Sandoz may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Simvastatin Sandoz<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Simvastatin Sandoz<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0simvastatin\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have liver problems<\/li><li>if you are pregnant or breastfeeding<\/li><li>if you are taking medicines containing one or more of the following active substances:<ul><li>itraconazole,\u00a0ketoconazole\u00a0, posaconazole or voriconazole (used to treat fungal infections)<\/li><li>erythromycin, clarithromycin, or telithromycin (used to treat\u00a0infections\u00a0)<\/li><li>HIV\u00a0protease inhibitors\u00a0such as indinavir, nelfinavir, ritonavir, and\u00a0saquinavir\u00a0(used in\u00a0HIV\u00a0infections\u00a0)<\/li><li>boceprevir or telaprevir (used to treat\u00a0hepatitis\u00a0C virus infection)<\/li><li>nefazodone (used to treat depression)<\/li><li>cobicistat<\/li><li>gemfibrozil (used to lower cholesterol)<\/li><li>ciclosporin (used in patients who have had an organ transplant)<\/li><li>danazol (a synthetic\u00a0hormone\u00a0used to treat\u00a0endometriosis, a condition in which the lining of the uterus grows outside the uterus).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Do not take more than 40 mg\u00a0of Simvastatin\u00a0Sandoz if you are taking lomitapide (used to treat a serious and rare genetic cholesterol condition).<\/p>\n\n\n\n<p>Ask your doctor if you are not sure if your medicine is listed above.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking&nbsp;Simvastatin&nbsp;Sandoz:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>about all your medical ailments, including\u00a0allergies.<\/li><li>if you have high alcohol consumption.<\/li><li>if you have or have had any liver disease.\u00a0Simvastatin\u00a0Sandoz may not be the right medicine for you.<\/li><li>if you are taking or have taken a medicine called fusidic acid (a medicine for bacterial\u00a0infections\u00a0) over the last 7 days, either by mouth or by\u00a0injection.\u00a0The combination of fusidic acid and\u00a0Simvastatin\u00a0Sandoz can lead to severe muscle problems (\u00a0rhabdomyolysis\u00a0).<\/li><li>if you are going to have surgery.\u00a0Discontinuation of treatment with\u00a0Simvastatin\u00a0Sandoz may need to be done for a short time.<\/li><li>if you are of Asian descent, then another\u00a0dose\u00a0may apply to you.<\/li><\/ul>\n\n\n\n<p>Your doctor should\u00a0prescribe\u00a0a blood test before you start taking\u00a0Simvastatin\u00a0Sandoz and if you have any symptoms of liver problems during treatment with\u00a0Simvastatin\u00a0Sandoz.\u00a0This blood test is performed to check your liver function.<\/p>\n\n\n\n<p>Your doctor may also want to&nbsp;prescribe&nbsp;blood tests to check your liver function after you start taking&nbsp;Simvastatin&nbsp;Sandoz.<\/p>\n\n\n\n<p>During treatment with this medicine, your doctor will closely monitor you if you have\u00a0diabetes\u00a0or are at risk of developing\u00a0diabetes.\u00a0You are more likely to be at risk for\u00a0diabetes\u00a0if you have high blood sugar and blood fat levels, are overweight, and have high\u00a0blood pressure.<\/p>\n\n\n\n<p>Tell your doctor if you have any serious lung disease.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you experience unexplained muscle aches, soreness, or weakness.\u00a0The reason for this is that in rare cases, the muscle problems can be serious and involve the breakdown of muscles with kidney damage as a result and in very rare cases, deaths have occurred.<\/strong><\/p>\n\n\n\n<p>Also, tell your doctor or pharmacist if you have persistent muscle weakness.\u00a0Additional tests and medications may be needed to diagnose and treat this.<\/p>\n\n\n\n<p>The risk of muscle breakdown is greater with higher\u00a0doses\u00a0of\u00a0Simvastatin\u00a0Sandoz, especially for\u00a0an 80 mg\u00a0dose.\u00a0The risk of muscle breakdown is also greater in some patients.\u00a0Talk to your doctor if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have a high alcohol consumption<\/li><li>you have kidney problems<\/li><li>you have thyroid problems<\/li><li>you are 65 years or older<\/li><li>you are a woman<\/li><li>if you have ever had muscle problems during treatment with cholesterol-lowering drugs, so-called statins or fibrates<\/li><li>you or a close relative has a hereditary muscle disease.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>The safety and efficacy of&nbsp;simvastatin&nbsp;have been studied in boys aged 10\u201317 years and in girls who had menstruated for at least one year (see section 3: How to take&nbsp;Simvastatin&nbsp;Sandoz).&nbsp;Simvastatin&nbsp;has not been studied in children under 10 years of age.&nbsp;For further information, consult a doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Simvastatin Sandoz<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines.\u00a0Taking\u00a0Simvastatin\u00a0Sandoz with any of the following medicines may increase the risk of muscle problems (some of these have already been listed in the section &#8216;Do not take Simvastatin Sandoz&#8217; above).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you need to take fusidic acid by mouth to treat a bacterial\u00a0infection<\/strong>, you will need to temporarily stop using\u00a0this medicine.\u00a0Your doctor will tell you when it is safe to start taking\u00a0Simvastatin\u00a0Sandoz again.\u00a0Taking\u00a0Simvastatin\u00a0Sandoz with fusidic acid may in rare cases lead to muscle weakness, tenderness, or pain (\u00a0rhabdomyolysis\u00a0).\u00a0See more information on\u00a0rhabdomyolysis\u00a0in section 4.<\/li><li>ciclosporin (often used by patients who have had an organ transplant)<\/li><li>danazol (a synthetic\u00a0hormone\u00a0used to treat\u00a0endometriosis, a condition in which the lining of the uterus grows outside the uterus)<\/li><li>drugs with an active substance such as itraconazole,\u00a0ketoconazole,\u00a0fluconazole, posaconazole, or voriconazole (used to treat fungal infections)<\/li><li>fibrates with an active substance such as gemfibrozil and bezafibrate (used to lower cholesterol)<\/li><li>erythromycin, clarithromycin, or telithromycin (used to treat bacterial\u00a0infections\u00a0)<\/li><li>HIV\u00a0protease inhibitors\u00a0such as indinavir, nelfinavir, ritonavir, and saquinavir (used to\u00a0treat\u00a0HIV\u00a0infections\u00a0)<\/li><li>medicines for\u00a0hepatitis\u00a0C, such as boceprevir, telaprevir, elbasvir, or grazoprevir (used to treat\u00a0hepatitis\u00a0C virus infection)<\/li><li>nefazodone (used to treat depression)<\/li><li>medicines containing the active substance cobicistat<\/li><li>amiodarone\u00a0(used to treat irregular heartbeat)<\/li><li>verapamil,\u00a0diltiazem,\u00a0or amlodipine (used to treat high\u00a0blood pressure, chest pain associated with heart disease or other heart problems)<\/li><li>lomitapide (used to treat a serious and rare genetic cholesterol condition)<\/li><li>daptomycin (a medicine used to treat complicated skin and soft tissue infections and\u00a0bacteremia\u00a0(presence of bacteria in the blood)).\u00a0The risk of\u00a0side effects\u00a0affecting the muscles may be higher when this medicine is taken during treatment with\u00a0simvastatin.\u00a0Your doctor may decide that you should\u00a0stop taking simvastatin\u00a0for a while.<\/li><li>colchicine (used to treat\u00a0gout\u00a0)<\/li><li>ticagrelor (used by patients who have had a heart attack or who have chest pain that is not well controlled).\u00a0Do not take more than 40 mg\u00a0of Simvastatin\u00a0Sandoz daily if you are taking ticagrelor.<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.&nbsp;It is especially important to tell your doctor if you are taking medicines with any of the following active substances:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anticoagulants with an active substance such as\u00a0warfarin, phenprocoumon, or acenocoumarol (\u00a0anticoagulants\u00a0)<\/li><li>fenofibrate (also used to lower cholesterol)<\/li><li>niacin\u00a0(also used to lower cholesterol)<\/li><li>rifampicin (used to treat\u00a0tuberculosis\u00a0).<\/li><\/ul>\n\n\n\n<p>Also, tell all doctors who prescribe you a new medicine that you are taking\u00a0Simvastatin\u00a0Sandoz.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Simvastatin Sandoz with food, drink, and alcohol<\/h2>\n\n\n\n<p>Grapefruit juice contains one or more substances that affect the body&#8217;s breakdown of certain drugs, including&nbsp;Simvastatin&nbsp;Sandoz.&nbsp;Intake of grapefruit juice should be avoided.<\/p>\n\n\n\n<p>Tell your doctor if you drink large amounts of alcohol.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Do not take\u00a0Simvastatin\u00a0Sandoz if you are pregnant, trying to conceive, or think you may be pregnant.\u00a0If you become pregnant while\u00a0taking Simvastatin\u00a0Sandoz, stop using the tablets immediately and contact your doctor.<\/p>\n\n\n\n<p>Do not take\u00a0Simvastatin\u00a0Sandoz if you are breastfeeding as it is unknown if the medicine passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Simvastatin&nbsp;Sandoz is not expected to affect your ability to drive or use machines.&nbsp;However, you should keep in mind that some people have experienced dizziness after taking&nbsp;Simvastatin&nbsp;Sandoz.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Simvastatin Sandoz contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Simvastatin Sandoz<\/h2>\n\n\n\n<p>Your doctor will decide which\u00a0dose\u00a0is right for you depending on your ailments, your ongoing treatment, and your risk profile.<\/p>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>You should continue with a cholesterol-lowering diet while taking&nbsp;Simvastatin&nbsp;Sandoz.<\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;is<\/strong>&nbsp;one tablet by mouth once a day.<\/p>\n\n\n\n<p><em>Adults<\/em><\/p>\n\n\n\n<p>The most common starting dose is 10, 20, or in some cases 40 mg daily.\u00a0Your doctor may, after at least 4 weeks, adjust your\u00a0dose\u00a0to a maximum of 80 mg per day.\u00a0<strong>Do not take more than 80 mg per day.<\/strong><\/p>\n\n\n\n<p>Your doctor may prescribe a lower&nbsp;dose&nbsp;for you, especially if you are taking certain medicines listed above or have certain kidney problems.<\/p>\n\n\n\n<p>A dose\u00a0of 80 mg is only recommended for adult patients with very high cholesterol levels and who are at high risk for heart disease and who have not achieved their treatment goals with lower\u00a0doses.<\/p>\n\n\n\n<p><em>Use for children and adolescents<\/em><\/p>\n\n\n\n<p>The recommended starting dose for children (10\u201317 years) is usually 10 mg daily until the evening.&nbsp;The maximum recommended&nbsp;dose&nbsp;is 40 mg daily.<\/p>\n\n\n\n<p><strong>Method of administration and duration of treatment<\/strong><\/p>\n\n\n\n<p>Take the medicine in the evening.&nbsp;You can take it with or without food.&nbsp;Continue to take the medicine unless your doctor has told you to stop.<\/p>\n\n\n\n<p>The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n<p>If your doctor has prescribed&nbsp;Simvastatin&nbsp;Sandoz with another cholesterol-lowering medicine that contains bile acid sequestrants, you should take&nbsp;Simvastatin&nbsp;Sandoz at least 2 hours before or 4 hours after taking the bile acid sequestrant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Simvastatin Sandoz than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.\u00a0If you overdose, your doctor should take symptomatic and supportive measures.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Simvastatin Sandoz<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.\u00a0Continue treatment with the prescribed\u00a0dose.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Simvastatin Sandoz<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist as your cholesterol level may rise again.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>If any of these serious\u00a0side effects\u00a0occur, stop taking your medicine and contact your doctor immediately or go to the nearest emergency department\u00a0:<\/strong><\/p>\n\n\n\n<p>The following rare serious&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>muscle aches, soreness, weakness, or cramps.\u00a0In rare cases, muscle problems can be serious and involve the breakdown of muscles with kidney damage as a result, and in very rare cases, deaths have occurred.<\/li><li>hypersensitivity (allergic reactions) including:<ul><li>swelling of the face, tongue, and throat, which may cause difficulty breathing (\u00a0angioedema\u00a0)<\/li><li>severe muscle pain, usually in the shoulders and hips<\/li><li>rash with weakness in arms, legs, and neck muscles<\/li><li>joint pain or\u00a0inflammation\u00a0(rheumatic polymyalgia)<\/li><li>inflammation\u00a0of blood vessels (\u00a0vasculitis\u00a0)<\/li><li>unusual bruising, skin changes and swelling (\u00a0dermatomyositis\u00a0),\u00a0hives, skin sensitivity to sun exposure, fever,\u00a0redness<\/li><li>shortness of breath (\u00a0dyspnoea\u00a0) and general malaise<\/li><li>lupus \u2011 similar disease picture (including rash, joint problems, and effects on\u00a0blood cells\u00a0)<\/li><\/ul><\/li><li>inflammation\u00a0of the liver with the following symptoms: yellowing of the skin and eyes,\u00a0itching, dark-colored urine or pale stools, feeling of tiredness or weakness, loss of appetite, and very rarely a liver failure<\/li><li>inflammation\u00a0of the pancreas, often with severe abdominal pain.<\/li><\/ul>\n\n\n\n<p>The following very rare serious&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a severe\u00a0allergic reaction\u00a0that causes difficulty breathing or dizziness (\u00a0anaphylaxis\u00a0)<\/li><li>gynecomastia\u00a0(breast augmentation in men)<\/li><li>rash that may occur on the skin or sores in the mouth (drug-related lichenoid rash)<\/li><li>muscle strain.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have also been reported:<\/p>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low\u00a0red blood cell count\u00a0(\u00a0anemia\u00a0)<\/li><li>numbness or weakness in the arms and legs<\/li><li>headache, &#8220;ant crawls&#8221;, dizziness<\/li><li>blurred vision and impaired vision<\/li><li>indigestion (abdominal pain, constipation, flatulence,\u00a0dyspepsia, diarrhea, nausea, vomiting)<\/li><li>rash,\u00a0itching, hair loss<\/li><li>weakness<\/li><li>elevations of liver function values \u200b\u200band a muscle enzyme (creatine kinase) in blood samples<\/li><li>memory loss, confusion.<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>difficulty sleeping<\/li><li>bad memory.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>\u00a0(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>erectile dysfunction<\/li><li>Depression<\/li><li>inflammation\u00a0of the lungs that causes difficulty breathing including persistent cough and\/or shortness of breath or fever<\/li><li>problems with tendons, sometimes aggravated by a tendon rupture<\/li><li>persistent muscle weakness.<\/li><\/ul>\n\n\n\n<p>Additional possible&nbsp;side effects&nbsp;that have been reported with certain statins:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sleep disorders including nightmares<\/li><li>sexual problems<\/li><li>Diabetes.\u00a0This is more likely if you have high blood sugar and blood fat levels, are overweight, and have high\u00a0blood pressure.\u00a0Your doctor will monitor you while you are taking this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Simvastatin Sandoz<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister\/tablet after EXP.\u00a0or EXP.\u00a0The expiration date is the last day of the specified month.\u00a0Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p><em>Blister:<\/em><\/p>\n\n\n\n<p>Store in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p><em>Tablet jar:<\/em><\/p>\n\n\n\n<p>Store in the original package.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is\u00a0simvastatin.\u00a0One film-coated tablet contains 10 mg\u00a0of simvastatin.<\/li><li>Other ingredients are:<br>Tablet core: pregelatinized\u00a0starch,\u00a0lactose monohydrate, microcrystalline cellulose, butyl hydroxy anisole (E320),\u00a0ascorbic acid\u00a0(E300), citric acid monohydrate (E330), magnesium stearate.<br>Film coating: hypromellose, talc, titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Simvastatin&nbsp;Sandoz 10 mg film-coated tablets are light red, oval, scored, convex tablets, marked with SIM 10 on one side.&nbsp;Simvastatin&nbsp;Sandoz 10 mg is available in the following packs:<\/p>\n\n\n\n<p>Blister (Al \/ PVC)<\/p>\n\n\n\n<p>Pack sizes: 10, 20, 28, 30, 40, 49, 50, 50 x 1, 60, 70, 80, 84, 90, 98 and 100 film-coated tablets.<\/p>\n\n\n\n<p>Polyethylene tablet jar with a screw cap<\/p>\n\n\n\n<p>Pack sizes: 10, 20, 28, 30, 40, 50, 84, 90, 100, 105 and 250 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Lek Pharmaceuticals dd, Verov\u0161kova 57, 1526 Ljubljana, Slovenia (tablet jar)<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>LEK SA, 16 Podlipie Street, 95-010 Stryk\u00f3w, Poland (blister packs)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>10 mg&nbsp;film-coated tabletssimvastatin What Simvastatin Sandoz is and what it is used for Simvastatin\u00a0Sandoz contains the active substance\u00a0simvastatin.\u00a0Simvastatin\u00a0Sandoz is a drug used to lower the levels of total cholesterol in the blood, the &#8220;bad&#8221;\u00a0cholesterol\u00a0(\u00a0LDL\u00a0cholesterol\u00a0), and blood fats, so-called\u00a0triglycerides. Simvastatin&nbsp;Sandoz also increases the levels of &#8220;good&#8221;&nbsp;cholesterol&nbsp;(&nbsp;HDL&nbsp;cholesterol&nbsp;).&nbsp;Simvastatin&nbsp;Sandoz belongs to a group of medicines called statins. Cholesterol\u00a0is one [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24153,24222,24122,24217,24221,24220,24218,24124,24219],"class_list":["post-23181","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-simvastatin","tag-benefits-of-simvastatin-sandoz","tag-simvastatin","tag-simvastatin-sandoz","tag-simvastatin-sandoz-side-effects","tag-simvastatin-sandoz-tablet","tag-what-is-simvastatin-sandoz","tag-what-simvastatin-is-used-for","tag-what-simvastatin-sandoz-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23181","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23181"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23181\/revisions"}],"predecessor-version":[{"id":23220,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23181\/revisions\/23220"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23181"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23181"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}