{"id":23022,"date":"2022-07-19T06:45:15","date_gmt":"2022-07-19T06:45:15","guid":{"rendered":"https:\/\/zeepedia.com\/?p=23022"},"modified":"2022-07-20T06:00:39","modified_gmt":"2022-07-20T06:00:39","slug":"sevorane","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sevorane\/","title":{"rendered":"Sevorane &#8211; Sevoflurane uses, dose and side effects"},"content":{"rendered":"\n<p>100%\u00a0inhalation vapor, liquid<br>Sevoflurane<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sevorane is and what it is used for<\/h2>\n\n\n\n<p>Sevorane is an anesthetic that is inhaled to achieve or maintain the deep anesthesia required during surgery.&nbsp;The drug causes you to lose consciousness and the ability to feel pain during surgery.&nbsp;The medicine is given by an anesthetist into the air you breathe before undergoing surgery.&nbsp;The anesthetist administers the medicine using a carburetor that converts the liquid into a gas so that you can inhale it.&nbsp;Sevorane is only used by healthcare professionals.&nbsp;Sevorane is given to both adults and children.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Sevorane<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Sevorane<\/h2>\n\n\n\n<p>Tell your doctor if any of the following apply or have affected you.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have reacted negatively in the past to anesthesia or if you know that you are hypersensitive to certain anesthetics, so-called halogenated\u00a0anesthetics, which are given.\u00a0You may have previously affected liver function, an increase in the number of\u00a0white blood cells,\u00a0or fever after anesthesia with one of these medicines.<\/li><li>if you have a known or suspected hereditary predisposition to an unusual type of severe high fever (\u00a0malignant\u00a0hyperthermia\u00a0).<\/li><\/ul>\n\n\n\n<p>There may also be other reasons why it is inappropriate to give anesthesia with Sevorane.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with Sevorane:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have low\u00a0blood pressure\u00a0and impaired breathing or dehydration.<\/li><li>if you have a known or suspected hereditary predisposition to an unusual type of severe high fever (\u00a0malignant\u00a0hyperthermia\u00a0).\u00a0In sensitive patients, certain anesthetics can cause a condition in the skeleton and muscles that can lead to an increase in the need for oxygen and an increase in temperature.<\/li><li>if you have impaired kidney function.<\/li><li>if you have some heart problems or irregular heartbeat.<\/li><li>if you are prone to cramps.<\/li><li>if you have or have previously had liver problems such as\u00a0hepatitis\u00a0(hepatitis), jaundice, or received treatment with drugs that impair liver function.\u00a0If you have previously had liver damage, jaundice, fever, or an increase in certain\u00a0white blood cells\u00a0(\u00a0eosinophils\u00a0), there may be a reason to give anesthesia with a medicine that does not contain sevoflurane.<\/li><li>if you as a patient have been repeatedly anesthetized with anesthetics similar to Sevorane within a relatively short interval.\u00a0This may increase the risk of liver damage.<\/li><li>if you have or have had neuromuscular diseases, e.g.\u00a0Duchenne muscular dystrophy.<\/li><li>if you are a child and have a neuromuscular disease called\u00a0Pompe&#8217;s disease.<\/li><li>if you have a so-called mitochondrial disease.<\/li><li>if you have elevated pressure in the brain (\u00a0intracranial pressure\u00a0).<\/li><\/ul>\n\n\n\n<p>As with other anesthetics, minor mood swings may persist for several days after anesthesia.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sevorane<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p>The following medicines may affect or be affected by Sevoflurane:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>muscle relaxants (eg pancuronium, vecuronium, atracurium, or succinylcholine).<\/li><li>painkillers such as opioids (morphine, alfentanil and sufentanil) or\u00a0benzodiazepines\u00a0.\u00a0When combined with Sevorane, the result may be a decrease in heart rate,\u00a0blood pressure,\u00a0and respiratory rate.<\/li><li>Using Sevorane with amphetamines or\u00a0ephedrine\u00a0may cause\u00a0an acute\u00a0increase in blood pressure.<\/li><li>use of Sevorane with certain medicines for high\u00a0blood pressure\u00a0(so-called beta-blockers\u00a0and calcium channel blockers) may affect the effect.<\/li><li>Concomitant use of herbal remedies containing\u00a0St. John&#8217;s wort\u00a0may cause severe hypotension and late recovery after anesthesia with Sevorane.<\/li><li>the use of\u00a0isoniazid\u00a0(medicine given for\u00a0tuberculosis\u00a0) or alcohol with Sevorane may affect plasma fluoride\u00a0concentrations.\u00a0Using\u00a0isoniazid\u00a0with Sevorane may increase the risk of liver effects with\u00a0isoniazid.<\/li><li>laughing gas.<\/li><li>The use of Sevorane with certain antidepressants, called non-selective\u00a0MAOIs, may increase the risk of problems during surgery.<\/li><\/ul>\n\n\n\n<p>Sevorane may affect the sensitivity of the heart to certain cardiac stimulants (\u00a0adrenaline,\u00a0isoprenaline,\u00a0and\u00a0norepinephrine\u00a0), which may increase the risk of irregular heartbeat.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use of Sevorane with food and drink<\/h2>\n\n\n\n<p>Before sleeping, do not eat or drink.&nbsp;The medical staff will give you detailed instructions on this.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p><em>Pregnancy<\/em>: There is no experience of use in pregnant women.\u00a0Sevorane should not be given to you if you are pregnant except after special consideration.<\/p>\n\n\n\n<p><em>Lactation<\/em>: There is no data on whether sevoflurane or its degradation products pass into breast milk.\u00a0Due to the lack of documented experience, you are advised not to breastfeed for 48 hours after receiving sevoflurane and discard milk produced during this time.\u00a0Talk to your doctor if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Sevorane has a profound effect on your ability to drive and use tools or machines.&nbsp;Do not drive or use any tools or machines until your doctor tells you it is safe.&nbsp;Anesthetics can affect wakefulness for several days.&nbsp;This can affect your ability to perform tasks that require sharp attention.&nbsp;Consult your anesthetist when it is safe for you to drive and use machines again.<a><\/a><br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Sevorane<\/h2>\n\n\n\n<p>Sevorane is only used by healthcare professionals.&nbsp;If you have any further questions, ask your doctor or pharmacist.<\/p>\n\n\n\n<p><em>Awakening:<\/em>&nbsp;Awakening generally occurs quickly after anesthesia with Sevorane.&nbsp;You may therefore need pain relief early after surgery.&nbsp;Recovery after anesthesia (anesthesia) will be ensured before you leave the recovery ward.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Sevorane than you should&nbsp;<\/h2>\n\n\n\n<p>Because Sevorane is given under strict supervision and dosed individually, it is unlikely that you will receive too much.&nbsp;If you receive too much Sevorane, your anesthetist will take the necessary action.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Sevorane can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or pharmacist.<\/p>\n\n\n\n<p>Sevoflurane, like all anesthetics, can cause transient heart-lung function that is transient.\u00a0Most\u00a0side effects\u00a0are mild to moderate in severity and transient.\u00a0Nausea, vomiting, and severe confusion (\u00a0delirium\u00a0) have occurred after surgery, which is common after\u00a0surgery\u00a0and anesthesia and may be due to the anesthetic gas, other medications given before or after surgery, and your reaction to the surgery.<\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects more than 1 user in 10):<\/p>\n\n\n\n<p>Concern<\/p>\n\n\n\n<p>Abnormally slow heartbeat<\/p>\n\n\n\n<p>Low&nbsp;blood pressure<\/p>\n\n\n\n<p>Cough<\/p>\n\n\n\n<p>Nausea<\/p>\n\n\n\n<p>Vomiting<\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects more than 1 user in 100):<\/p>\n\n\n\n<p>Somnolence<\/p>\n\n\n\n<p>Dizziness<\/p>\n\n\n\n<p>Headache<\/p>\n\n\n\n<p>Palpitation<\/p>\n\n\n\n<p>High&nbsp;blood pressure<\/p>\n\n\n\n<p>Difficulty breathing<\/p>\n\n\n\n<p>Cramp in the larynx<\/p>\n\n\n\n<p>Increased salivation<\/p>\n\n\n\n<p>Overindulge<\/p>\n\n\n\n<p>Fever<\/p>\n\n\n\n<p>Abnormal blood sugar<\/p>\n\n\n\n<p>Abnormal liver function tests<\/p>\n\n\n\n<p>Deviating the number of\u00a0white blood cells<\/p>\n\n\n\n<p>Elevated fluoride (a form of fluoride) in the blood **<\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects 1 to 10 users in 1,000):<\/p>\n\n\n\n<p>Atrioventricular block (effect on the electrical signal in the heart)<\/p>\n\n\n\n<p><strong>Side effects&nbsp;are without known frequency<\/strong><\/p>\n\n\n\n<p>Allergic&nbsp;shock<\/p>\n\n\n\n<p>Hypersensitivity reaction<\/p>\n\n\n\n<p>Dystonia&nbsp;(involuntary muscle contractions)<\/p>\n\n\n\n<p>Muscle cramps<\/p>\n\n\n\n<p>Cardiac arrest<\/p>\n\n\n\n<p>Spasmodic contraction of the muscles in the trachea<\/p>\n\n\n\n<p>Respiratory distress<\/p>\n\n\n\n<p>Wheezing<\/p>\n\n\n\n<p>Liver inflammation<\/p>\n\n\n\n<p>Liver failure<\/p>\n\n\n\n<p>Disintegration and death of liver cells<\/p>\n\n\n\n<p>Itching<\/p>\n\n\n\n<p>Hives<\/p>\n\n\n\n<p>Contact dermatitis<\/p>\n\n\n\n<p>Swelling of the face<\/p>\n\n\n\n<p>Very high and fast temperature rise<\/p>\n\n\n\n<p>Discomfort in the chest<\/p>\n\n\n\n<p>Cardiac arrhythmias<\/p>\n\n\n\n<p>In children (from two months of age) and young adults with an increased risk of having seizures, it may be necessary to use another anesthetic.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sevorane<\/h2>\n\n\n\n<p>No special storage instructions.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is sevoflurane<\/p>\n\n\n\n<p>The other ingredients are water.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Sevorane is a clear, colorless liquid that is delivered in an amber-colored plastic bottle with a size of 250 ml or a package containing 6 250 ml plastic bottles.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>My\u00a0information<strong> is provided by:<\/strong><\/p>\n\n\n\n<p>AbbVie AB<\/p>\n\n\n\n<p>Box 1523<\/p>\n\n\n\n<p>171 29 Solna<\/p>\n\n\n\n<p>Tel: 08-684 44 600<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>AbbVie Srl<\/p>\n\n\n\n<p>SR148 Pontina km 52 snc<\/p>\n\n\n\n<p>Campoverde di Aprilia<\/p>\n\n\n\n<p>04011 Aprilia (LT)<\/p>\n\n\n\n<p>Italy<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sevorane is an anesthetic that is inhaled to achieve or maintain the deep anesthesia required during surgery.\u00a0The drug causes you to lose consciousness and the ability to feel pain during surgery.\u00a0The medicine is given by an anesthetist into the air you breathe before undergoing surgery.\u00a0The anesthetist administers the medicine using a carburetor that converts the liquid into a gas so that you can inhale it.\u00a0Sevorane is only used by healthcare professionals.\u00a0Sevorane is given to both adults and children.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[24058,24063,24054,24057,24059,24062,24055,24060,24056],"class_list":["post-23022","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-sevoflurane","tag-benefits-of-sevorane","tag-sevoflurane","tag-sevoflurane-side-effects","tag-sevorane","tag-sevorane-side-effects","tag-what-is-sevoflurane","tag-what-is-sevorane","tag-what-sevoflurane-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23022","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=23022"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23022\/revisions"}],"predecessor-version":[{"id":23057,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/23022\/revisions\/23057"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=23022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=23022"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=23022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}