{"id":22974,"date":"2022-07-18T07:44:41","date_gmt":"2022-07-18T07:44:41","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22974"},"modified":"2022-07-19T06:37:31","modified_gmt":"2022-07-19T06:37:31","slug":"sevelamer-carbonate-winthrop","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sevelamer-carbonate-winthrop\/","title":{"rendered":"Sevelamer carbonate Winthrop &#8211; Sevelamer carbonate uses, dose and side effects"},"content":{"rendered":"\n<p>800 mg&nbsp;film-coated tablets<br>sevelamer carbonate<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sevelamer carbonate Winthrop is and what it is used for<\/h2>\n\n\n\n<p>Sevelamer carbonate Winthrop contains the active substance sevelamer carbonate.&nbsp;It binds&nbsp;phosphate&nbsp;from the food in the digestive tract and thus lowers the serum levels of phosphorus in the blood.<\/p>\n\n\n\n<p>This medicine is used to control&nbsp;hyperphosphatemia&nbsp;(high levels of phosphate in the blood) in<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>adult patients receiving dialysis (a blood purification technique).\u00a0It can be used to treat patients who receive\u00a0hemodialysis\u00a0(through a blood filtration machine) or\u00a0peritoneal dialysis\u00a0(where fluid is pumped into the abdominal cavity and an internal\u00a0membrane\u00a0in the body filters the blood);<\/li><li>patients with\u00a0chronic\u00a0(long-term) kidney disease with serum phosphorus levels (in the blood) greater than or equal to 1.78 mmol \/ l, who do not receive\u00a0dialysis.<\/li><\/ul>\n\n\n\n<p>This medicine should be used together with other treatment methods such as calcium supplements and&nbsp;vitamin&nbsp;D to prevent the development of skeletal disease.<\/p>\n\n\n\n<p>Elevated levels of serum phosphorus can lead to hard deposits in the body which are called calcifications.\u00a0These deposits can make the blood vessels stiff so that it becomes more difficult to pump the blood into the body.\u00a0Elevated levels of serum phosphorus can also lead to\u00a0itchy\u00a0skin, red eyes, skeletal pain, and\u00a0fractures.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to densevelamer carbonate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have low levels of&nbsp;phosphate&nbsp;in your blood (your doctor will check this for you)<\/li><li>if you have intestinal obstruction<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Sevelamer carbonate Winthrop:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have swallowing problems.\u00a0Your doctor may instead prescribe sevelamer carbonate powder for\u00a0oral\u00a0suspension.<\/li><li>if you have problems with\u00a0motility\u00a0(mobility) in the stomach and intestines<\/li><li>if you have an active intestinal inflammation<\/li><li>if you have had major surgery on your stomach or intestines<\/li><\/ul>\n\n\n\n<p>Talk to your doctor during treatment with Sevelamer carbonate Winthrop:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you experience severe abdominal pain, gastrointestinal upset, or blood in the stool (\u00a0gastrointestinal\u00a0bleeding).\u00a0These symptoms may be due to severe\u00a0inflammatory\u00a0bowel disease caused by sevelamer crystals in the intestine.\u00a0Contact your doctor who will decide whether to continue treatment or not.<\/li><\/ul>\n\n\n\n<p><em>Additional treatments<\/em>&nbsp;:<\/p>\n\n\n\n<p>Due to either your kidney condition or your dialysis treatment, you can:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>develop low or high calcium levels in the blood.\u00a0As this medicine does not contain\u00a0calcium, your doctor may prescribe extra calcium tablets.<\/li><li>have a low amount of\u00a0vitamin\u00a0D in the blood.\u00a0Therefore, your doctor may check the levels of\u00a0vitamin\u00a0D in your blood and\u00a0prescribe\u00a0more\u00a0vitamin\u00a0D if needed.\u00a0If you do not take any multivitamin supplements, you may also get low levels of\u00a0vitamins\u00a0A, E, K, and\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a>\u00a0in your blood therefore your doctor may check these levels and\u00a0prescribe\u00a0vitamin supplements if needed.<\/li><li>get abnormal levels of\u00a0bicarbonate\u00a0in the blood and increased acidity in the blood and other body tissues.\u00a0Your doctor should check the levels of bicarbonate in your blood.<\/li><\/ul>\n\n\n\n<p><em>Important to consider for patients receiving peritoneal dialysis:<\/em><\/p>\n\n\n\n<p>You may develop\u00a0peritonitis\u00a0(peritonitis) in connection with\u00a0peritoneal dialysis.\u00a0This risk can be reduced if you carefully follow the sterile methods during bag changes.\u00a0You should tell your doctor immediately if you get new signs or symptoms of abdominal discomfort, abdominal swelling, abdominal pain, abdominal pain or hard\/stiff abdomen, constipation, fever, chills, nausea, or vomiting.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Do not give this medicine to children under 6 years of age as the safety and efficacy in children (under 6 years of age) have not been studied.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You should not take Sevelamer carbonate Winthrop at the same time as\u00a0ciprofloxacin\u00a0(an\u00a0antibiotic\u00a0).<\/li><li>If you are taking medicines for heart rhythm problems or epilepsy, you should consult your doctor when taking Sevelamer carbonate Winthrop.<\/li><li>Sevelamer carbonate Winthrop may reduce the effects of such medicines as cyclosporine, mycophenolate mofetil, and tacrolimus (medicines used to\u00a0suppress\u00a0the immune system).\u00a0Your doctor will advise you if you are taking these medicines.<\/li><li>Thyroid hormone deficiency can be less common in some people taking levothyroxine (used to treat low levels of thyroid hormone) and Sevelamer carbonate Winthrop.\u00a0Therefore, your doctor may check the levels of thyroid-stimulating hormone\u00a0in your blood more closely.<\/li><li>Medicines to treat heartburn and acid reflux from your stomach or esophagus, such as omeprazole, pantoprazole, or lansoprazole, so-called &#8220;proton pump inhibitors&#8221;, may reduce the effect of Sevelamer carbonate Winthrop.\u00a0Your doctor may want to check the phosphate levels in your blood.<\/li><\/ul>\n\n\n\n<p>Your doctor will regularly check the risk of Sevelamer carbonate Winthrop being affected or affected by other medicines.<\/p>\n\n\n\n<p>In some cases when Sevelamer carbonate Winthrop is taken while you are taking another medicine, your doctor may ask you to take this medicine 1 hour before or 3 hours after taking Sevelamer carbonate Winthrop.&nbsp;Your doctor may also want to check the levels of the other medicine in your blood.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0<\/p>\n\n\n\n<p>The potential risk of Sevelamer carbonate Winthrop during human pregnancy is unknown.&nbsp;Talk to your doctor who will decide if you can continue treatment or not.<\/p>\n\n\n\n<p>It is not known if Sevelamer carbonate Winthrop can pass into breast milk and affect your baby.\u00a0Talk to your doctor who will decide if you can breastfeed or not and if it is necessary to stop treatment with Sevelamer carbonate Winthrop.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Sevelamer carbonate Winthrop is unlikely to affect your ability to drive or use machines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Excipients<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per tablet, ie it is essentially &#8216;sodium-free&#8217;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Your doctor will base&nbsp;dose&nbsp;one on your serum phosphorus level.<\/p>\n\n\n\n<p>The recommended starting dose of this medicine for adults and the elderly is one to two tablets of 800 mg at each meal, ie 3 times a day.\u00a0If you are not sure, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<p>Take Sevelamer carbonate Winthrop after a meal or with food.<\/p>\n\n\n\n<p>The tablets must be swallowed whole.\u00a0They must not be crushed, chewed, or broken into pieces.<\/p>\n\n\n\n<p>Initially, your doctor will check the phosphorus levels in your blood at 2-4 week intervals and may adjust the Sevelamer carbonate Winthrop&nbsp;dose&nbsp;as needed to achieve an appropriate phosphate level.<\/p>\n\n\n\n<p>Follow the diet prescribed by your doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Sevelamer carbonate Winthrop than you should<\/h2>\n\n\n\n<p>In the event of an overdose, contact your doctor immediately.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<p>If you have missed a\u00a0dose, skip this\u00a0dose\u00a0and take the next\u00a0dose\u00a0at the usual time with meals.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<p>Taking Sevelamer carbonate Winthrop is important for maintaining a proper level of phosphate in your blood.&nbsp;Quitting Sevelamer carbonate Winthrop would lead to significant consequences such as calcification of the blood vessels.&nbsp;If you are considering stopping treatment with Sevelamer carbonate Winthrop, talk to your doctor or pharmacist first.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Constipation is a very common\u00a0side effect. It can be an early symptom of intestinal blockage.\u00a0In case of constipation, you should contact a doctor or pharmacist.<\/p>\n\n\n\n<p>Some\u00a0side effects\u00a0can be serious.\u00a0If you get any of the following\u00a0side effects, seek medical advice immediately:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reaction\u00a0(symptoms include rash, hives, swelling, and difficulty breathing).\u00a0This is a very rare\u00a0side effect\u00a0(may affect up to 1 in 10,000 people).<\/li><li>Intestinal blockage (symptoms include severe bloating (abdominal pain, swelling, or cramps), and severe constipation) have been reported.\u00a0No known frequency (frequency can not be calculated from available data).<\/li><li>Holes in the intestinal wall (symptoms include severe abdominal pain, chills, fever, nausea, vomiting, or sore abdomen).\u00a0No known frequency.<\/li><li>Severe\u00a0inflammation\u00a0of the colon (symptoms include: severe abdominal pain, gastrointestinal upset, or blood in the stool [gastrointestinal bleeding]) and precipitation of sevelamer crystals in the intestinal mucosa have been reported.\u00a0No known frequency.<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have been reported in patients taking Sevelamer carbonate Winthrop:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><li>pain in the upper abdomen<\/li><li>nausea<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea<\/li><li>abdominal pain<\/li><li>indigestion<\/li><li>weather voltage<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(frequency can not be calculated from available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cases of\u00a0itching<\/li><li>rash<\/li><li>slow bowel motility (mobility)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sevelamer carbonate Winthrop<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the can and carton after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Close the jar tightly.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is sevelamer carbonate.\u00a0Each film-coated tablet contains 800 mg of sevelamer carbonate.<\/li><li>The other ingredients are microcrystalline cellulose, sodium chloride, zinc stearate, hypromellose (E464), diacetylated\u00a0monoglycerides, black iron oxide (E172), isopropyl alcohol, and propylene glycol.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Sevelamer carbonate Winthrop film-coated tablets are white to off-white tablets with \u201cSC800\u201d debossed on one side.\u00a0The tablets are packaged in high-density polyethylene cans fitted with a child-resistant polypropylene cap and an induction seal.<\/p>\n\n\n\n<p>Pack sizes:&nbsp;<\/p>\n\n\n\n<p>Each jar contains 30 or 180 tablets.<\/p>\n\n\n\n<p>Packs of 1 can with 30 or 180 tablets without outer carton.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Genzyme Europe BV<\/p>\n\n\n\n<p>Paasheuvelweg 25<br>1105 BP Amsterdam<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Genzyme Ireland Ltd.<\/p>\n\n\n\n<p>IDA Industrial Park<\/p>\n\n\n\n<p>Old Kilmeaden Road<\/p>\n\n\n\n<p>Waterford<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><br>Contact the representative of the marketing authorization holder to find out more about this medicine.<\/p>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Tel: +46 (0) 8 634 50 00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sevelamer carbonate Winthrop contains the active substance sevelamer carbonate.\u00a0It binds\u00a0phosphate\u00a0from the food in the digestive tract and thus lowers the serum levels of phosphorus in the blood.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[23982,23994,22706,23989,23993,23992,2210,23990,22708,23991],"class_list":["post-22974","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-sevelamer-carbonate","tag-benefits-of-sevelamer-carbonate-winthrop","tag-sevelamer-carbonate","tag-sevelamer-carbonate-winthrop","tag-sevelamer-carbonate-winthrop-side-effects","tag-sevelamer-carbonate-winthrop-tabelt","tag-tablet","tag-what-is-sevelamer-carbonate-winthrop","tag-what-sevelamer-carbonate-is-used-for","tag-what-sevelamer-carbonate-winthrop-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22974"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22974\/revisions"}],"predecessor-version":[{"id":23010,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22974\/revisions\/23010"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}