{"id":22909,"date":"2022-07-14T06:52:32","date_gmt":"2022-07-14T06:52:32","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22909"},"modified":"2022-07-18T07:19:59","modified_gmt":"2022-07-18T07:19:59","slug":"seroquel-depot","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/seroquel-depot\/","title":{"rendered":"Seroquel Depot &#8211; Quetiapine uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg, 150 mg, 200 mg, 300 mg, 400 mg&nbsp;prolonged-release tablets&nbsp;are<br>quetiapine<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Seroquel Depot is and what it is used for<\/h2>\n\n\n\n<p>Seroquel\u00a0Depot\u00a0contains a substance called quetiapine.\u00a0Quetiapine belongs to a group of medicines called antipsychotics.\u00a0Seroquel\u00a0Depot\u00a0can be used to treat several ailments, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bipolar depression and depressive episodes in real depression: when you may feel depressed or depressed, guilt-laden, lacking energy, have a poor appetite or have sleep problems.<\/li><li>Mania: when you may feel very upset, elated, upset, enthusiastic, hyperactive, or have poor judgment with elements of aggressive and fragmented behavior.<\/li><li>Schizophrenia: when you may see, hear or feel things that do not exist, believe in things that are not real, or feel unusually suspicious, anxious, confused, tense, or depressed.<\/li><\/ul>\n\n\n\n<p>When Seroquel\u00a0Depot\u00a0is taken to treat depressive episodes in case of major depression, it is taken in addition to other medications used to treat this disease.<\/p>\n\n\n\n<p>Your doctor may want you to continue taking Seroquel&nbsp;Depot&nbsp;even when you feel better.<\/p>\n\n\n\n<p>Quetiapine contained in Seroquel\u00a0Depot\u00a0may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Seroquel Depot<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Seroquel Depot:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to quetiapine or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are taking any of the following medicines:<ul><li>certain medicines for&nbsp;HIV<\/li><li>azoles (medicines for fungal infections)<\/li><li>erythromycin and clarithromycin (medicines for&nbsp;infections&nbsp;)<\/li><li>nefazodone (antidepressant).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>If you are not sure, talk to your doctor or pharmacist before taking Seroquel\u00a0Depot.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Seroquel Depot:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you or someone in your family has or has had a heart problem, such as heart rhythm disorders, weak heart muscle, or\u00a0inflammation\u00a0of the heart, or if you are taking any medicines that may affect your heart rate<\/li><li>if you have low\u00a0blood pressure<\/li><li>if you have had a\u00a0stroke, especially if you are older<\/li><li>if you have liver problems<\/li><li>if you have ever had a seizure (\u00a0epilepsy\u00a0)<\/li><li>if you have\u00a0diabetes\u00a0or are at risk of getting\u00a0diabetes.\u00a0If you have it, your doctor may need to measure your blood sugar level when you use Seroquel\u00a0Depot.<\/li><li>if you know you have had low\u00a0white blood cell counts\u00a0in the past (which may or may not have been caused by other medicines)<\/li><li>if you are older and suffer from dementia (a loss of brain function).\u00a0If this is true for you, do not take Seroquel\u00a0Depot, as the group of medicines to which Seroquel\u00a0Depot\u00a0belongs may increase the risk of\u00a0stroke, or in some cases the risk of death, in elderly people with dementia.<\/li><li>if you are older and suffering from Parkinson&#8217;s disease\/parkinsonism<\/li><li>if you or someone in your family has had a blood clot, as similar medicines have been linked to the formation of blood clots<\/li><li>if you have or have had a condition where you stop breathing for short periods during your normal night&#8217;s sleep (called &#8220;sleep apnea&#8221;) and take medicines that reduce the normal activity of the brain (&#8220;sedatives&#8221;)<\/li><li>if you have or have had a condition where you cannot empty the bladder completely (\u00a0urinary retention\u00a0), have an enlarged\u00a0prostate, a blockage in the intestines, or increased pressure inside the eye.\u00a0These conditions are sometimes caused by drugs (called &#8220;anticholinergics&#8221;) that affect the function of nerve cells to treat certain conditions.<\/li><li>if you have or have had problems with alcohol or drug abuse.<\/li><\/ul>\n\n\n\n<p>Tell your doctor immediately if you experience any of the following after taking Seroquel Depot:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a combination of fever, severe muscle stiffness, sweating, or decreased consciousness (a condition called malignant neuroleptic syndrome).\u00a0You may need immediate medical attention.<\/li><li>uncontrollable movements, especially on the face or tongue.<\/li><li>dizziness or troublesome drowsiness.\u00a0In older patients, this could increase the risk of accidental injuries (by falling)<\/li><li>seizures<\/li><li>prolonged and painful\u00a0erection\u00a0(priapism)<\/li><li>rapid irregular heartbeat even at rest, palpitations, breathing problems, chest pain, or unexplained fatigue.\u00a0The doctor needs to examine your heart and, if necessary, send (refer) you immediately to a cardiologist.<\/li><\/ul>\n\n\n\n<p>Such conditions can be caused by this type of drug.<\/p>\n\n\n\n<p>Talk to a doctor as soon as possible if you get:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever,\u00a0flu-like symptoms, sore throat, or any other\u00a0infection, as this could be due to a very low\u00a0white\u00a0blood cell count, which may require discontinuation of Seroquel\u00a0Depot\u00a0and\/or treatment for\u00a0infection<\/li><li>constipation along with persistent pain in the stomach or constipation that does not respond to treatment, as this can lead to a more severe blockage of the intestine.<\/li><li>Suicidal thoughts and worsening depression<br>You who are depressed can sometimes have thoughts of wanting to hurt yourself or commit suicide.\u00a0These symptoms may worsen when you start treatment, as it takes time for a drug of this type to take effect, usually about 2 weeks, but sometimes longer.\u00a0Thoughts of this type can also increase if you suddenly stop taking your medicine.\u00a0These thoughts can be common if you are a young adult.\u00a0Clinical studies\u00a0have shown that young adults (younger than 25 years) with depression have an increased risk of suicidal thoughts and\/or thoughts of self-harm.<br><br>Contact a doctor as soon as possible or go to the nearest hospital if you have thoughts of injuring yourself or committing suicide.\u00a0It can be helpful to tell a relative or close friend that you are depressed.\u00a0Feel free to ask them to read this leaflet.\u00a0You can also ask them to tell you if they think the depression is getting worse or if they think your behavior is changing.<\/li><\/ul>\n\n\n\n<p><strong>Severe skin reactions (SCAR)<\/strong><\/p>\n\n\n\n<p>Severe skin reactions (SCARs) that can be life-threatening or fatal have been reported in very rare cases during treatment with this medicine.&nbsp;These usually appear as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stevens-Johnson syndrome\u00a0(SJS), is a widespread rash with blisters and skin detachment, especially around the mouth, nose, eyes, and genitals<\/li><li>Toxic epidermal necrolysis\u00a0(TEN), a more serious form that causes extensive skin detachment<\/li><li>Drug-induced skin rash with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS) consisting of\u00a0flu-like symptoms\u00a0with rash, fever, swollen\u00a0glands,\u00a0and abnormal results of blood tests (including an increase in\u00a0white blood cells\u00a0(\u00a0eosinophilia\u00a0) and liver enzymes).<\/li><li>Acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0(AGEP), small blisters filled with var<\/li><li>Erythema multiforme (EM), skin rash with itchy irregular red spots<\/li><\/ul>\n\n\n\n<p>Stop using Seroquel&nbsp;Depot&nbsp;if you get these symptoms and contact your doctor or see a doctor immediately.<\/p>\n\n\n\n<p><strong>Weight gain<\/strong><\/p>\n\n\n\n<p>Some patients taking Seroquel&nbsp;Depot&nbsp;have been shown to gain weight.&nbsp;You and your doctor should check your weight regularly.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Seroquel&nbsp;Depot&nbsp;should not be used by children and adolescents under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Seroquel Depot<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Do not take Seroquel&nbsp;Depot&nbsp;if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain medicines for&nbsp;HIV<\/li><li>azoles (medicines for fungal infections)<\/li><li>erythromycin or clarithromycin (medicines for&nbsp;infections&nbsp;)<\/li><li>nefazodone (antidepressant).<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>epilepsy drugs (such as&nbsp;phenytoin&nbsp;or carbamazepine)<\/li><li>medicines for high&nbsp;blood pressure<\/li><li>barbiturates&nbsp;(medicines for sleep disorders)<\/li><li>thioridazine or lithium (other antipsychotics)<\/li><li>drugs that affect the heartbeat, such as drugs that can cause an imbalance in the&nbsp;electrolytes&nbsp;(low levels of&nbsp;potassium&nbsp;or&nbsp;magnesium&nbsp;) such as&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;) or certain&nbsp;antibiotics&nbsp;(medicines for&nbsp;infections&nbsp;)<\/li><li>drugs that can cause constipation<\/li><li>drugs (called &#8220;anticholinergics&#8221;) that affect the way nerve cells work to treat certain conditions.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before stopping any of these medicines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Seroquel Depot with food, drink, and alcohol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Seroquel\u00a0Depot\u00a0can be affected by food and you should therefore take your tablets at least 1 hour before a meal or before bedtime.<\/li><li>You should be careful about how much alcohol you drink as the combination of Seroquel\u00a0Depot\u00a0and alcohol can make you sleepy.<\/li><li>Do not drink grapefruit juice while taking Seroquel\u00a0Depot.\u00a0It may affect the way medicine works.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.\u00a0You should not take Seroquel\u00a0Depot\u00a0during pregnancy unless you have discussed it with your doctor.<\/p>\n\n\n\n<p>You should not take Seroquel\u00a0Depot\u00a0if you are breastfeeding.<\/p>\n\n\n\n<p>The following symptoms, which are similar to those that may occur when you stop taking the medicine, may occur in newborns of mothers who have used Seroquel\u00a0Depot\u00a0during the last trimester (last three months of pregnancy): tremors, muscle stiffness, and\/or muscle weakness, drowsiness, anxiety, breathing problems and difficulty eating.\u00a0If your child has any of these symptoms, you may need to consult a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Your tablets can make you sleepy.&nbsp;Do not drive or use any tools or machines until you know how the tablets affect you.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Seroquel Depot contains lactose<\/h2>\n\n\n\n<p>Seroquel&nbsp;Depot&nbsp;contains&nbsp;lactose&nbsp;(a sugar).&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Seroquel&nbsp;Depot&nbsp;<\/strong><strong>contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>Seroquel\u00a0Depot\u00a050 mg\u00a0prolonged-release tablets, Seroquel\u00a0Depot\u00a0150 mg\u00a0prolonged-release tablets,\u00a0and Seroquel\u00a0Depot\u00a0200 mg\u00a0prolonged-release tablets\u00a0contain less than 1 mmol (23 mg)\u00a0sodium\u00a0per tablet, ie are essential &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p>Seroquel\u00a0Depot\u00a0300 mg\u00a0prolonged-release tablets\u00a0and Seroquel\u00a0Depot\u00a0400 mg\u00a0prolonged-release tablets\u00a0contain 27 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per tablet.\u00a0This corresponds to 1.35% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.<\/p>\n\n\n\n<p><strong>Effects on drug tests in urine<\/strong><\/p>\n\n\n\n<p>If you are taking a urine sample for a drug test, using Seroquel may make you test positive for&nbsp;methadone&nbsp;or certain antidepressants called&nbsp;tricyclic antidepressants&nbsp;(TCAs).&nbsp;This can happen when certain test methods are used, even though you may not be taking&nbsp;methadone&nbsp;or TCA, in which case a more specific test may be performed.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Seroquel Depot<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Your doctor will decide on your starting dose.&nbsp;The maintenance dose (the daily&nbsp;dose&nbsp;one) depends on your illness and your needs but is normally between 150 mg and 800 mg.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You should take the tablets once a day.<\/li><li>Do not divide, chew or crush the tablets.<\/li><li>Swallow the tablets whole with a glass of water.<\/li><li>Take the tablets without food (at least 1 hour before a meal or at night &#8211; your doctor will tell you which time is best).<\/li><li>Do not drink grapefruit juice while taking Seroquel\u00a0Depot.\u00a0It may affect the way medicine works.<\/li><li>Do not stop taking your tablets even if you feel better unless your doctor tells you to.<\/li><\/ul>\n\n\n\n<p><strong>Liver problem<\/strong><\/p>\n\n\n\n<p>If you have liver problems, your doctor may change your\u00a0dose.<\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>If you are older, your doctor may change your\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Seroquel&nbsp;Depot&nbsp;should not be used by children and adolescents under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Seroquel Depot than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor or hospital for risk assessment and advice.\u00a0If you take more\u00a0doses\u00a0than your doctor prescribes, you may feel drowsy, dizzy, and feel your heart beating abnormally.\u00a0Bring the Seroquel\u00a0Depot\u00a0tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Seroquel Depot<\/h2>\n\n\n\n<p>If you forget to take a tablet, take it as soon as you remember.&nbsp;If it&#8217;s soon time for the next tablet, wait until then.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Seroquel Depot<\/h2>\n\n\n\n<p>If you suddenly stop taking Seroquel\u00a0Depot, you may have difficulty sleeping, feel nauseous or experience headaches, diarrhea, vomiting, dizziness, or feel irritable.\u00a0Your doctor may suggest that you reduce the\u00a0dose\u00a0gradually before stopping your treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Very common: may affect more than 1 user in 10<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness (may lead to falls), headache,\u00a0dry mouth<\/li><li>drowsiness (may disappear with time when taking Seroquel\u00a0Depot\u00a0) (may lead to falls)<\/li><li>discontinuation symptoms (symptoms that occur when you stop taking Seroquel\u00a0Depot\u00a0) include difficulty falling asleep (insomnia), malaise (nausea), headache, diarrhea, vomiting, dizziness, and irritability.\u00a0It is advisable to stop taking the medicine gradually over at least 1-2 weeks.<\/li><li>weight gain<\/li><li>abnormal muscle movements, e.g.\u00a0difficult to start movements, tremors, a feeling of restlessness or muscle stiffness without pain<\/li><li>altered levels of certain fats (\u00a0triglycerides\u00a0and total\u00a0cholesterol\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Common: may affect up to 1 in 10 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fast heartbeat<\/li><li>feeling that the heart is pounding, rushing, or skipping a heartbeat<\/li><li>constipation, upset stomach (digestive problems)<\/li><li>impotence<\/li><li>swelling in arms or legs<\/li><li>drop in blood pressure when you get up.\u00a0It may make you feel dizzy or faint (which may lead to falls)<\/li><li>increased blood sugar content<\/li><li>dimsyn<\/li><li>strange dreams and nightmares<\/li><li>increased feelings of hunger<\/li><li>feeling of irritation<\/li><li>speech and language disorders<\/li><li>suicidal thoughts and worsening of your depression<\/li><li>shortness of breath<\/li><li>vomiting (mainly in the elderly)<\/li><li>fever<\/li><li>altered levels of thyroid hormones in the blood<\/li><li>decreased levels of certain types of\u00a0blood\u00a0cells<\/li><li>increased content of liver enzymes measured in blood samples<\/li><li>increased levels of the\u00a0hormone\u00a0et\u00a0prolactin\u00a0in the blood.\u00a0An increase in the\u00a0hormone\u00a0et\u00a0prolactin\u00a0may in rare cases lead to the following:<ul><li>Men and women can get a swelling of the breasts and unexpected production of breast milk.<\/li><li>in women, menstruation may cease or become irregular.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Uncommon: may affect up to 1 in 100 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>epilepsy\u00a0or seizures<\/li><li>allergic reactions that may include raised lumps or streaks, skin swelling, and swelling around the mouth<\/li><li>the feeling of discomfort in the legs (also called restless legs syndrome)<\/li><li>difficulty swallowing<\/li><li>involuntary movements, especially of the face and tongue<\/li><li>sexual\u00a0dysfunction<\/li><li>diabetes<\/li><li>change in heart electrical activity that can be seen on\u00a0ECG\u00a0(\u00a0QT\u00a0prolongation)<\/li><li>a slower-than-normal heart rate may occur at the beginning of treatment and may be associated with low\u00a0blood pressure\u00a0and fainting<\/li><li>difficulty urinating<\/li><li>fainting (may lead to falls)<\/li><li>nasal congestion<\/li><li>reduced levels of\u00a0red blood cells<\/li><li>lowered\u00a0sodium\u00a0levels in the blood<\/li><li>worsening\u00a0diabetes<\/li><li>confusion.<\/li><\/ul>\n\n\n\n<p><strong>Rare: may affect up to 1 in 1,000 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a combination of fever, sweating, muscle stiffness, drowsiness, or fainting (a condition called &#8220;malignant neuroleptic syndrome&#8221;)<\/li><li>yellow skin and eyes (jaundice)<\/li><li>hepatitis\u00a0_\u00a0_<\/li><li>persistent and painful\u00a0erection\u00a0(priapism)<\/li><li>swelling of the breasts and unexpected production of breast milk (\u00a0galactorrhea\u00a0)<\/li><li>menstrual disorder<\/li><li>blood clots in the veins, especially in the legs (with symptoms such as swelling, pain, and\u00a0redness\u00a0) can be passed on in the blood vessels to the lungs and cause chest pain and difficulty breathing.\u00a0If you get symptoms similar to these, you should see a doctor immediately.<\/li><li>that you walk, talk, eat or have other activities while you sleep<\/li><li>decreased body temperature (\u00a0hypothermia\u00a0)<\/li><li>pancreatitis<\/li><li>a condition (so-called \u201cmetabolic syndrome\u201d) where you may have a combination of at least 3 of the following signs: an increase in belly fat, a decrease in \u201cgood cholesterol\u201d (\u00a0HDL-C\u00a0), an increase in a type of fat in blood called\u00a0triglycerides, high\u00a0blood pressure\u00a0and an increase in blood sugar<\/li><li>a combination of fever,\u00a0flu-like symptoms, sore throat, or any other\u00a0infection\u00a0with very low\u00a0white blood cell count, a condition called\u00a0agranulocytosis<\/li><li>blockage of the intestine<\/li><li>increased levels of creatine phosphokinase in the blood (a substance that comes from the muscles).<\/li><\/ul>\n\n\n\n<p><strong>Very rare: may affect up to 1 in 10,000 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe rash, blisters, or red spots on the skin<\/li><li>severe\u00a0allergic reaction\u00a0(\u00a0anaphylactic reaction\u00a0) which may cause difficulty breathing or\u00a0shock<\/li><li>rapid swelling of the skin, usually around the eyes, lips, and neck (\u00a0angioedema\u00a0)<\/li><li>a serious disease with blistering of the skin, mouth, eyes, and genitals (\u00a0Stevens-Johnson syndrome\u00a0).\u00a0See section 2.<\/li><li>disturbed secretion of a\u00a0hormone\u00a0that regulates urine volume<\/li><li>degradation of muscle fibers and muscle pain (\u00a0rhabdomyolysis\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>No known frequency: can not be calculated from the available data<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin rash with irregular red spots (erythema multiforme).\u00a0See section 2.<\/li><li>rapidly emerging areas of red skin with small blisters filled with white \/ yellow fluid called\u00a0acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0(AGEP).\u00a0See section 2.<\/li><li>severe, sudden\u00a0allergic reaction\u00a0with symptoms such as fever, blistering, and peeling of the skin (\u00a0toxic epidermal necrolysis\u00a0).\u00a0See section 2.<\/li><li>drug-induced skin rash with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS) consisting of\u00a0flu-like symptoms\u00a0with rash, fever, swollen\u00a0glands,\u00a0and abnormal results of blood tests (including an increase in\u00a0white blood cells\u00a0(\u00a0eosinophilia\u00a0) and liver enzymes).\u00a0See section 2.<\/li><li>Problems with discontinuation of the drug may occur in newborns of mothers who have used Seroquel\u00a0Depot\u00a0during pregnancy.<\/li><li>stroke.<\/li><li>heart muscle disease (\u00a0cardiomyopathy\u00a0).<\/li><li>Myocarditis (\u00a0myocarditis\u00a0).<\/li><li>Inflammation\u00a0of the blood vessels (\u00a0vasculitis\u00a0) often with a rash with small red or purple nodules.<\/li><\/ul>\n\n\n\n<p>Seroquel&nbsp;Depot&nbsp;is a type of medicine that can cause heart rhythm disturbances.&nbsp;Such disorders can be serious and, in severe cases, fatal.<\/p>\n\n\n\n<p>Some\u00a0side effects\u00a0are only visible if you take a blood sample.\u00a0These include altered levels of certain fats (\u00a0triglycerides\u00a0and total\u00a0cholesterol\u00a0) or sugar in the blood, altered levels of thyroid hormones in the blood, elevated levels of liver enzymes, decreased number of certain types of\u00a0blood cells, decreased levels of\u00a0red blood cells, increased levels of creatine phosphokinase (a substance in the muscles) in the blood, lowered\u00a0sodium\u00a0levels in the blood and elevated levels in the blood of the\u00a0hormone\u00a0et\u00a0prolactin.\u00a0An increase in the\u00a0hormone\u00a0et\u00a0prolactin\u00a0can in rare cases lead to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Men and women can get a swelling of the breasts and unexpected production of breast milk.<\/li><li>in women, menstruation may cease or become irregular.<\/li><\/ul>\n\n\n\n<p>Your doctor may ask you to have blood tests regularly.<\/p>\n\n\n\n<p><strong>Additional&nbsp;side effects&nbsp;are in children and adolescents<\/strong><\/p>\n\n\n\n<p>The same&nbsp;side effects&nbsp;that can occur in adults can also occur in children and adolescents.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may be more common in children and adolescents or may not occur at all in adults:<\/p>\n\n\n\n<p><strong>Very common: may affect more than 1 user in 10<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The increased amount of the\u00a0hormone\u00a0et\u00a0prolactin\u00a0in the blood.\u00a0Increased amounts of the\u00a0hormone\u00a0et\u00a0prolactin\u00a0may in rare cases lead to the following:<ul><li>Breasts can swell in both boys and girls and unexpectedly form breast milk<\/li><li>Menstruation can stop or become irregular in girls<\/li><\/ul><\/li><li>Increased appetite<\/li><li>Vomiting<\/li><li>Abnormal muscle movements.\u00a0These include difficulty starting muscle movements, tremors, restlessness, or muscle stiffness without pain<\/li><li>Increased\u00a0blood pressure.<\/li><\/ul>\n\n\n\n<p><strong>Common: may affect up to 1 in 10 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Weakness, fainting (may lead to falls)<\/li><li>nasal congestion<\/li><li>That you feel annoyed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Seroquel Depot<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures are to<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is quetiapine.\u00a0Seroquel\u00a0Depot\u00a0tablets contain 50 mg, 150 mg, 200 mg, 300 mg or 400 mg of quetiapine (as quetiapine fumarate).<\/li><li>Other ingredients are Tablet core: microcrystalline cellulose, sodium citrate,\u00a0lactose monohydrate, magnesium stearate, and hypromellose.Tablet cover: hypromellose, macrogol, titanium dioxide (E171).\u00a0The 50 mg, 200 mg, and 300 mg tablets also contain yellow iron oxide (E172) and the 50 mg tablets contain red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>All\u00a0prolonged-release tablets\u00a0are capsule-shaped and imprinted with XR and strength.\u00a0The 50 mg tablets are peach-colored, the 150 mg tablets are white, the 200 mg tablets are yellow, the 300 mg tablets are light yellow and the 400 mg tablets are white.<\/p>\n\n\n\n<p>Pack sizes of 10, 30, 50, 60, and 100 tablets are registered for all strengths.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing authorization holder: AstraZeneca AB, 151 85 S\u00f6dert\u00e4lje.<\/p>\n\n\n\n<p>Manufacturer: AstraZeneca GmbH, Tinsdaler Weg 183, 22880 Wedel, Germany.<\/p>\n\n\n\n<p>AstraZeneca AB, G\u00e4rtunav\u00e4gen, 151 85 S\u00f6dert\u00e4lje.<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p><strong>Seroquel XR:<\/strong>\u00a0Belgium, Cyprus, Estonia, Greece, Ireland, Croatia, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Slovakia, Hungary, and Austria.<\/p>\n\n\n\n<p><strong>Seroquel Prolong:<\/strong>&nbsp;Denmark, Finland, Iceland, Spain, Czech Republic and Germany (Seroquel Prolong\u00ae 50 mg Retard Tablet, Seroquel Prolong\u00ae 150 mg Retard Tablet, Seroquel Prolong\u00ae 200 mg Retard Tablet, Seroquel Prolong\u00ae 300 mg Retard Tablet, Seroquel Prolong\u00ae 400 mg .<\/p>\n\n\n\n<p><strong>Seroquel Depot:<\/strong>&nbsp;Norway and Sweden.<\/p>\n\n\n\n<p><strong>Seroquel SR:<\/strong>&nbsp;Portugal and Slovenia.<\/p>\n\n\n\n<p><strong>Xeroquel LP:<\/strong>&nbsp;France.<\/p>\n\n\n\n<p><strong>Seroquel XL:<\/strong>&nbsp;Great Britain.<\/p>\n\n\n\n<p><strong>Seroquel compresses to prolonged release:<\/strong>&nbsp;Italien.<\/p>\n\n\n\n<p><strong>Quetiapine XR AstraZeneca:<\/strong>&nbsp;The Netherlands.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>50 mg, 150 mg, 200 mg, 300 mg, 400 mg&nbsp;prolonged-release tablets&nbsp;arequetiapine What Seroquel Depot is and what it is used for Seroquel\u00a0Depot\u00a0contains a substance called quetiapine.\u00a0Quetiapine belongs to a group of medicines called antipsychotics.\u00a0Seroquel\u00a0Depot\u00a0can be used to treat several ailments, such as: Bipolar depression and depressive episodes in real depression: when you may feel depressed [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[8744,8746,8748,23956,23960,23959,8745,23957,8747,23958],"class_list":["post-22909","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-quetiapine","tag-quetiapine-side-effects","tag-quetiapine-tablet","tag-seroquel-depot","tag-seroquel-depot-side-effects","tag-seroquel-depot-tabelt","tag-what-is-quetiapine","tag-what-is-seroquel-depot","tag-what-quetiapine-is-used-for","tag-what-seroquel-depot-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22909"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22909\/revisions"}],"predecessor-version":[{"id":22955,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22909\/revisions\/22955"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22909"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22909"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}