{"id":22760,"date":"2022-07-07T10:29:17","date_gmt":"2022-07-07T10:29:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22760"},"modified":"2022-07-08T10:27:53","modified_gmt":"2022-07-08T10:27:53","slug":"selesyn","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/selesyn\/","title":{"rendered":"Selesyn &#8211; Sodium selenite pentahydrate uses, dose and side effects"},"content":{"rendered":"\n<p>Solution 50 micrograms\/ml Selenium solution for&nbsp;injection<br>(as sodium selenite pentahydrate)<\/p>\n\n\n\n<p>Read<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Selesyn is and what it is used for<\/h2>\n\n\n\n<p>Selesyn is a drug that belongs to the group of mineral supplements.&nbsp;Sodium selenite pentahydrate, the active substance in Selesyn, is a source of selenium which is an important trace element in nutrient intake to ensure efficient metabolism.<\/p>\n\n\n\n<p>Selesyn is used for adults.<\/p>\n\n\n\n<p>Your doctor has recommended this medicine because tests to measure the level of selenium in your blood have shown that you have a selenium deficiency that cannot be corrected by selenium intake through your diet.<\/p>\n\n\n\n<p>Sodium selenite pentahydrate contained in Selesyn may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Selesyn<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Selesyn<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sodium selenite pentahydrate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have selenosis (selenium poisoning).&nbsp;For symptoms of selenosis, see section 3 &#8220;If you have had too much Selesyn&#8221;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Selesyn.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children under 18 years of age as safety and efficacy have not been established.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Selesyn<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The solution for injection must not be mixed with so-called reducing agents such as&nbsp;vitamin&nbsp;C.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>There is limited information on the use of sodium selenite pentahydrate in pregnant women.&nbsp;No adverse effects of sodium selenite pentahydrate are expected on pregnancy or the unborn child, provided that the medicine is used in case of proven selenium deficiency.<\/p>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<p>Selenium is excreted in breast milk.&nbsp;However, at approved&nbsp;doses&nbsp;of Selesyn, no effects on breastfed newborns\/infants are expected.<\/p>\n\n\n\n<p>Fertility<\/p>\n\n\n\n<p>There is no information available on the role of selenium in&nbsp;fertility.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>There is no effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Selesyn solution for injection\/infusion contains sodium<\/h2>\n\n\n\n<p><em>Selesyn 100 micrograms, solution for injection or infusion<\/em><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per 2 ml&nbsp;ampoule, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p><em>Selesyn 50 micrograms\/ml, solution for injection or infusion<\/em><\/p>\n\n\n\n<p>This medicine contains up to 35.70 mg and 71.39 mg of&nbsp;sodium&nbsp;respectively (the main ingredient in table salt\/table salt) in each&nbsp;vial&nbsp;of 10 ml and 20 ml respectively.&nbsp;This corresponds to 1.8% and 3.6%, respectively, of the highest recommended daily intake of&nbsp;sodium&nbsp;for adults.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Selesyn<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Selesyn 100 micrograms solution for injection\/infusion is used as a single dose only.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;for adults is:<\/p>\n\n\n\n<p>100 micrograms selenium (1&nbsp;ampoule&nbsp;Selesyn 100 micrograms solution for injection \/ infusion or 2 ml from 10 ml or 20 ml vial Selesyn 50 micrograms \/ ml solution for injection \/ infusion) daily.&nbsp;For a short time, up to 300 micrograms of selenium (3 ampoules of&nbsp;Selesyn&nbsp;100 micrograms solution for injection or infusion or 6 ml from a 10 ml or 20 ml vial of Selesyn 50 micrograms\/ml solution for injection\/infusion) can be given daily.<\/p>\n\n\n\n<p>To treat extreme selenium deficiency, your doctor may temporarily increase the&nbsp;dose&nbsp;by up to 2000 micrograms of selenium (2 vials of 20 ml Selesyn 50 micrograms\/ml solution for injection\/infusion) daily.<\/p>\n\n\n\n<p>Use<\/p>\n\n\n\n<p>Selesyn, the solution for injection\/infusion should always be given to you by a nurse or doctor.<\/p>\n\n\n\n<p>Selesyn, a solution for injection or infusion, is given&nbsp;intramuscularly&nbsp;(&nbsp;injection&nbsp;into a muscle) or&nbsp;intravenously&nbsp;(&nbsp;injection&nbsp;into a vein), or as an additive to&nbsp;infusion.<\/p>\n\n\n\n<p>Duration of treatment:<\/p>\n\n\n\n<p>How long you should be treated is decided by your doctor.<\/p>\n\n\n\n<p>Your nurse or doctor will take regular blood tests to check the levels of selenium in your blood to monitor the effectiveness of your treatment.&nbsp;As soon as the selenium content is normal, your treatment with Selesyn will be completed.<\/p>\n\n\n\n<p>Selesyn should only be given when&nbsp;oral&nbsp;administration&nbsp;is not possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have had too much Selesyn<\/h2>\n\n\n\n<p>If you have had more Selesyn than you should, you may experience the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>acute&nbsp;(short-term): garlic-smelling breath, fatigue, nausea, diarrhea, and abdominal pain or<\/li><li>chronic (long-term): can cause symptoms that affect the growth of nails and hair and can lead to&nbsp;peripheral&nbsp;polyneuropathy&nbsp;(a disease of a nerve or nerve pathway that can feel numb or tingling).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to get Selesyn<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten injection\/infusion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Selesyn<\/h2>\n\n\n\n<p>There are no special instructions if you stop using Selesyn.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>No known frequency (cannot be calculated from the available data):<\/strong><\/p>\n\n\n\n<p>After&nbsp;intramuscular&nbsp;use, you may feel pain in the place where your nurse or doctor has given Selesyn.<\/p>\n\n\n\n<p><em>Reporting<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Selesyn<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Selesyn is for single use only.&nbsp;Your nurse or doctor will give you this medicine immediately after opening the&nbsp;ampoule&nbsp;or bottle.&nbsp;Your doctor or nurse will inject the remaining 10 ml or 20 ml vial of Selesyn 50 micrograms\/ml solution for injection\/infusion.<\/p>\n\n\n\n<p>Your nurse or doctor will not give you this medicine if the&nbsp;ampoule&nbsp;or bottle is damaged or if the solution is cloudy.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and the&nbsp;ampoule&nbsp;or vial label after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is:&nbsp;sodium selenite pentahydrate<\/p>\n\n\n\n<p><em>Selesyn 100 micrograms, solution for injection or infusion, 2 ml<\/em><\/p>\n\n\n\n<p>1&nbsp;ampoule&nbsp;with 2 ml solution for injection\/infusion contains: 0.333 mg sodium selenite pentahydrate, equivalent to 100 micrograms of selenium<\/p>\n\n\n\n<p><em>Selesyn 50 micrograms \/ ml, solution for injection \/ infusion, 10 ml (500 micrograms)<\/em><\/p>\n\n\n\n<p>One&nbsp;vial&nbsp;of 10 ml solution for injection\/infusion contains 1.67 mg sodium selenite pentahydrate equivalent to 500 micrograms seof lenium.<\/p>\n\n\n\n<p><em>Selesyn 50 micrograms \/ ml, solution for injection \/ infusion, 20 ml (1000 micrograms)<\/em><\/p>\n\n\n\n<p>One&nbsp;vial&nbsp;of 20 ml solution for injection\/infusion contains 3.33 mg sodium selenite pentahydrate equivalent to 1000 micrograms selenium.<\/p>\n\n\n\n<p>The other ingredients are:&nbsp;sodium chloride, water for injections,&nbsp;hydrochloric acid<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Selesyn is a clear, colorless solution.<\/p>\n\n\n\n<p><em><u>Selesyn 100 micrograms, solution for injection or infusion<\/u><\/em><\/p>\n\n\n\n<p>Glass ampoule&nbsp;containing 2 ml solution for injection\/infusion<\/p>\n\n\n\n<p>Pack sizes: 5, 10, and 50&nbsp;ampoules<\/p>\n\n\n\n<p><em><u>Selesyn 50 micrograms\/ml, solution for injection or infusion<\/u><\/em><\/p>\n\n\n\n<p>Glass vial with chlorobutyl rubber stopper containing 10 ml or 20 ml solution for injection\/infusion.<\/p>\n\n\n\n<p><em><u>10 ml&nbsp;vial&nbsp;(500 micrograms)<\/u><\/em><\/p>\n\n\n\n<p>Pack sizes: 2, 10 and 50 (5 x 10) 20 ml&nbsp;vial&nbsp;(1000 micrograms) Pack sizes: 2, 10 and 50 (5 x 10)<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>biosyn Arzneimittel GmbH<\/p>\n\n\n\n<p>Schorndorfer Strasse 32<\/p>\n\n\n\n<p>70734 Fellbach<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Denmark: Selesyn 100 micrograms, solution for injection or infusion<\/p>\n\n\n\n<p>Denmark: Selesyn 50 micrograms\/ml, solution for injection or infusion<\/p>\n\n\n\n<p>Sweden: Selesyn 100 micrograms, solution for injection or infusion<\/p>\n\n\n\n<p>Sweden: Selesyn 50 micrograms \/ ml, solution for injection \/ infusion<\/p>\n\n\n\n<p>Germany: selenase\u00ae 100 micrograms solution for injection \/ solution for infusion<\/p>\n\n\n\n<p>Germany: selenase\u00ae 50 micrograms \/ ml solution for injection \/ infusion solution<\/p>\n\n\n\n<p>France: SELENIUM PANPHARMA 100 micrograms, injectable solution<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selesyn is a drug that belongs to the group of mineral supplements.\u00a0Sodium selenite pentahydrate, the active substance in Selesyn, is a source of selenium which is an important trace element in nutrient intake to ensure efficient metabolism.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[23780,23782,23786,23785,23776,23779,23783,23777,23784,23778],"class_list":["post-22760","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-sodium-selenite-pentahydrate","tag-selesyn","tag-selesyn-side-effects","tag-selesyn-tablet","tag-sodium-selenite-pentahydrate","tag-sodium-selenite-pentahydrate-side-effects","tag-what-is-selesyn","tag-what-is-sodium-selenite-pentahydrate","tag-what-selesyn-is-used-for","tag-what-sodium-selenite-pentahydrate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22760"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22760\/revisions"}],"predecessor-version":[{"id":22795,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22760\/revisions\/22795"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22760"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22760"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}