{"id":22664,"date":"2022-07-05T07:25:47","date_gmt":"2022-07-05T07:25:47","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22664"},"modified":"2022-07-05T10:39:24","modified_gmt":"2022-07-05T10:39:24","slug":"sapimol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/sapimol\/","title":{"rendered":"Sapimol &#8211; Ipratropium bromide \/ Salbutamol container uses, dose and side effects"},"content":{"rendered":"\n<p>0.5 mg \/ 2.5 mg per 2.5 ml&nbsp;nebuliser solution&nbsp;,&nbsp;single&nbsp;dose<br>ipratropium bromide \/ salbutamol container<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Sapimol is and what it is used for<\/h2>\n\n\n\n<p>Sapimol belongs to a class of medicines called&nbsp;bronchodilators&nbsp;that facilitate breathing by opening up the airways.<\/p>\n\n\n\n<p>Sapimol is used to treat breathing problems in people who have long-term breathing difficulties.<\/p>\n\n\n\n<p>Ipratropium bromide and\u00a0salbutamol\u00a0contained in Sapimol may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Sapimol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Sapimol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ipratropium bromide, salbutamol sulfate, atropine, or any of the other ingredients of this medicine (see section 6).<\/li><li>if you have a heart condition called\u00a0cardiomyopathy\u00a0(ie heart rhythm disorders caused by\u00a0inflammation\u00a0of the heart muscle)<\/li><li>if you have a fast and irregular heart rhythm (so-called tachyarrhythmia)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Sapimol:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are pregnant, planning to become pregnant, or if you are breast-feeding<\/li><li>if you have\u00a0diabetes<\/li><li>if you have or have had a heart condition or have recently had a heart attack<\/li><li>if you have high\u00a0blood pressure, irregular heartbeat, or angina<\/li><li>if you have an overactive\u00a0thyroid gland<\/li><li>if you have\u00a0cystic fibrosis<\/li><li>if you have problems emptying your bladder<\/li><li>if you have or think you may have an eye disease called\u00a0glaucoma\u00a0(increased pressure in the eyes)<\/li><li>if you have or have had liver or kidney disease<\/li><li>if you have been informed that you have\u00a0pheochromocytoma.\u00a0This is a rare\u00a0tumor\u00a0that can cause restlessness, and high\u00a0blood pressure\u00a0and make the heart beat faster.<br>A condition called lactic acidosis (increased acidity (\u00a0lactic acid\u00a0) in the blood) has been reported in association with high\u00a0doses\u00a0of\u00a0salbutamol, especially in patients being treated for\u00a0acute\u00a0bronchospasm\u00a0(spasm of the trachea) (see sections 3 and 4).\u00a0An increase in lactate levels (lactic acid level) can lead to difficulty breathing and hyperventilation (rapid and shallow breathing) even if other symptoms such as wheezing improve.\u00a0If you experience that your medicine does not work as well as usual and you need to use the nebulizer more than your doctor has prescribed, talk to a doctor immediately.<br>Good oral hygiene and regular dental check-ups are recommended, especially for children.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Sapimol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including any of the following medicines, which may or may not be affected by Sapimol:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Steroids\u00a0include\u00a0prednisolone<\/li><li>Xanthines such as theophylline<\/li><li>Beta-blockers\u00a0such as propranolol or\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/\">timolol<\/a>\u00a0as may reduce the effect of your medicine<\/li><li>Diuretics\u00a0(&#8220;diuretics&#8221;) including non-potassium\u00a0-sparing diuretics\u00a0such as\u00a0furosemide\u00a0or indapamide.<\/li><li>Digoxin\u00a0(used in\u00a0heart failure\u00a0)<\/li><li>Other drugs that facilitate breathing such as\u00a0terbutaline<\/li><li>Anticholinergic drugs (for\u00a0asthma, gastrointestinal irritation,\u00a0Parkinson&#8217;s disease,\u00a0and\u00a0incontinence\u00a0(involuntary bladder emptying))<\/li><li>Some medicines are used to treat depression (so-called monoamine oxidase inhibitors and\u00a0tricyclic antidepressants\u00a0).<\/li><\/ul>\n\n\n\n<p>Some anesthetic gases may&nbsp;interact&nbsp;with your medicine.&nbsp;If you are going to have surgery under anesthesia, tell your anesthetist that you are taking Sapimol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0If you are breastfeeding, do not use Sapimol unless your doctor tells you to.\u00a0If you become pregnant while you are being treated with this medicine, tell your doctor as soon as possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Sapimol has no known effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether\u00a0<em>you<\/em>\u00a0are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Sapimol<\/h2>\n\n\n\n<p>Always use Sapimol exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Your doctor will probably tell you that you should use the nebulizer at regular times each day and you should always follow your doctor&#8217;s instructions.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;for adults (including the elderly) and children over the age of 12 is 1&nbsp;single dose&nbsp;3-4 times daily.<\/p>\n\n\n\n<p>Sapimol is not recommended for use in children under 12 years of age.<\/p>\n\n\n\n<p><strong>General instructions:<\/strong><\/p>\n\n\n\n<p>Open one foil package at a time and use all the single-dose containers in it before opening the next foil package.\u00a0After use, the remaining\u00a0single-dose container\u00a0should always be returned to the foil package and the foil package should be returned to the carton.\u00a0As single-dose containers do not contain\u00a0preservatives, they must be used immediately after opening.<\/p>\n\n\n\n<p><strong>Instructions for use<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Prepare the nebulizer according to the manufacturer&#8217;s and physician&#8217;s dosing instructions.<\/li><li>Remove the single-dose containers from the foil package.\u00a0Remove a\u00a0single-dose container\u00a0from the card single-dose container\u00a0and put the rest back in the foil package, which in turn is put back in the box (see figure A).\u00a0Never use medicines from a\u00a0single-dose container\u00a0that has been opened before or if the solution is discolored.<\/li><li>Hold the single-dose container upright and turn off the top (see figure B).<\/li><li>Unless your doctor recommends otherwise, squeeze the entire contents into the nebulizer chamber (see Figure C).<\/li><li>Discard the used single-dose container.<\/li><li>Turn on the nebulizer and inhale the &#8220;steam&#8221; deeply and calmly using the face mask and mouthpiece.\u00a0If you use a face mask, make sure that it closes tightly.\u00a0Protect your eyes from the steam as it may otherwise cause pain or discomfort.\u00a0This is especially important if you have\u00a0glaucoma.<\/li><li>How long it takes for the nebulizer to convert your medicine to steam depends on the type of equipment you use.\u00a0When steam no longer comes out of the face mask, your treatment is complete.<\/li><li>Wash\u00a0the nebulizer, face mask, and\/or your mouthpiece with warm soap solution after each use and rinse well.<\/li><\/ol>\n\n\n\n<p>Sapimol should only be used in a\u00a0nebulizer\u00a0approved by your doctor and should not be mixed with other medicines in the same\u00a0nebulizer.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20070626000016#\" rel=\"noopener\"><\/a><br>A<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20070626000016#\" rel=\"noopener\"><\/a><br>B<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20070626000016#\" rel=\"noopener\"><\/a><br>C<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Contact a doctor immediately if:<\/strong><\/p>\n\n\n\n<p>\u2022&nbsp;<strong>The current&nbsp;dosage&nbsp;does not improve<\/strong><\/p>\n\n\n\n<p>\u2022&nbsp;<strong>Your breathing difficulties get worse<\/strong><\/p>\n\n\n\n<p>\u2022&nbsp;<strong>You experience pressure over the chest<\/strong><\/p>\n\n\n\n<p><strong>The above are signs that your symptoms are not adequately controlled by the treatment and that you may need another or additional treatment.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Sapimol than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital immediately for an assessment of the risk and advice.<\/p>\n\n\n\n<p>If you have taken a slightly larger\u00a0dose\u00a0than usual, you may have hot flashes, feel shaky, feel weak, feel restless and\/or dizzy, have an abnormal heart rhythm, have chest pain, feel your heart beat faster than normal, and get loud or low\u00a0blood pressure.\u00a0If you have taken more medicine than you should, tell your doctor immediately or go to the nearest hospital.\u00a0If you feel shaky, do not drive.\u00a0Take this leaflet and a\u00a0single-dose container\u00a0of your medicine with you so that they know at the hospital which medicine you have taken.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Sapimol<\/h2>\n\n\n\n<p>If you forget to take a\u00a0dose\u00a0at the right time, take it instead when it is time for the\u00a0<strong>next\u00a0<\/strong>dose\u00a0or before you get wheezing.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>All medicines can cause allergic reactions, although severe allergic reactions are very rare.\u00a0Contact a doctor immediately if you suddenly experience wheezing, difficulty breathing, swelling of the eyelids, face or lips, rash, or\u00a0itching\u00a0(especially if it occurs all over the body.)<\/strong><\/p>\n\n\n\n<p><strong>In rare cases, inhaled medicines such as Sapimol may cause\u00a0acute\u00a0wheezing and\/or shortness of breath.\u00a0If this happens, stop using the medicine immediately and contact a doctor.<\/strong><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Dry mouth<\/li><li>Speech difficulties or hoarseness<\/li><li>Palpitation&nbsp;er (palpitations)<\/li><li>Feeling sick (nausea)<\/li><li>Problems focusing the eyes<\/li><li>Fast&nbsp;pulse<\/li><li>Cough<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>Vomiting<\/li><li>Difficulty emptying the bladder<\/li><li>High&nbsp;blood pressure<\/li><li>Tremors or tremors<\/li><li>Nervousness<\/li><li>Irregular heartbeat<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sweating<\/li><li>Constipation<\/li><li>Muscle weakness, muscle aches\/cramps<\/li><li>Lowered\u00a0blood pressure\u00a0and circulatory problems<\/li><li>Allergic reactions (see above)<\/li><li>Restlessness<\/li><li>Mouth and throat irritation<\/li><li>Breathing difficulties (see above)<\/li><li>Memory disorders<\/li><li>Anxiety and depression<\/li><li>Hyperactivity in children<\/li><li>Eye problems, including eye pain and\u00a0glaucoma\u00a0(increased pressure in the eyes)<\/li><\/ul>\n\n\n\n<p>Has been reported (occurs in an unknown number of users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Caries<\/li><li>A condition called lactic acidosis (increased acidity (\u00a0lactic acid\u00a0)) can cause abdominal pain, hyperventilation (rapid and shallow breathing), difficulty breathing (although other symptoms such as wheezing improve), and cold hands and feet, irregular heartbeat, or thirst.<\/li><\/ul>\n\n\n\n<p>If the solution or vapor enters the eyes, you may have pain or irritation in the eyes, blurred vision, or see light rings (halo phenomena) or colored dots.\u00a0Therefore, you must be careful and protect your eyes when using your medicine.<\/p>\n\n\n\n<p>Sometimes your medicine can cause a decrease in the level of potassium in your blood, which can make you nauseous.&nbsp;If you get nausea, tell your doctor so any blood tests can be taken.<\/p>\n\n\n\n<p>Although it is not known exactly how often it occurs, some people can sometimes experience chest pain (caused by heart problems such as angina).\u00a0Tell your doctor\/nurse if you get these symptoms while you are being treated with Sapimol, but do not stop treatment unless your doctor recommends it.<\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get\u00a0any side effects, talk to your doctor, pharmacist, or nurse.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly (see details below).\u00a0By reporting\u00a0side effects, you can help increase the safety of medicines.<\/p>\n\n\n\n<p>L\u00e4kemedelsverket<br>Box 26<br>751 03 Uppsala<\/p>\n\n\n\n<p><a href=\"http:\/\/www.lakemedelsverket.se\/\" target=\"_blank\" rel=\"noreferrer noopener\">www.lakemedelsverket.se<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Sapimol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store the single-dose containers in the foil package in the original packaging.&nbsp;Sensitive to light.&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date \/ EXP which is stated on the carton after \u201cEXP\u201d \/ EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not use this medicine if the packaging is damaged or if the solution is discolored or cloudy.<\/p>\n\n\n\n<p>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances are: ipratropium bromide (0.5 mg \/ 2.5 ml) and&nbsp;salbutamol&nbsp;(as sulphate (2.5 mg \/ 2.5 ml)<\/p>\n\n\n\n<p>The other ingredients are sodium chloride,\u00a0hydrochloric acid,\u00a0and water for injections.<\/p>\n\n\n\n<p>Each\u00a02.5 ml Sapimol single-dose container contains 0.5 mg ipratropium bromide and 2.5 mg\u00a0salbutamol\u00a0(\u00a0as sulfate).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Sapimol is a nebulizer&nbsp;solution&nbsp;.<\/p>\n\n\n\n<p>Your medicine is contained in\u00a0single-dose\u00a0plastic containers containing 2.5 ml in a clear solution intended for nebulization (conversion to vapor for\u00a0inhalation\u00a0).\u00a0Cards with 10\u00a0single-dose containers\u00a0are packed in foil bags, which in turn are packed in cardboard boxes containing 10, 20, 40, 60, 80, 100, or 120\u00a0ampoules\u00a0of Sapimol.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Rivopharm Ltd.<\/p>\n\n\n\n<p>17 Corrig Road<\/p>\n\n\n\n<p>Sandyford, Dublin 18<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Laboratory Unither,<\/p>\n\n\n\n<p>Espace Industriel Nord, 151 rue Adr\u00e9 Durouchez- CS 28028<\/p>\n\n\n\n<p>80084 Amiens, Cedex 2,<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><em>Skin:<\/em><\/p>\n\n\n\n<p>SanoSwiss UAB<\/p>\n\n\n\n<p>Lvovo 25-701<\/p>\n\n\n\n<p>LT-09320 Vilnius<\/p>\n\n\n\n<p>Lithuania<\/p>\n\n\n\n<p>info@sanoswiss.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>0.5 mg \/ 2.5 mg per 2.5 ml&nbsp;nebuliser solution&nbsp;,&nbsp;single&nbsp;doseipratropium bromide \/ salbutamol container What Sapimol is and what it is used for Sapimol belongs to a class of medicines called&nbsp;bronchodilators&nbsp;that facilitate breathing by opening up the airways. Sapimol is used to treat breathing problems in people who have long-term breathing difficulties. Ipratropium bromide and\u00a0salbutamol\u00a0contained in [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18530],"tags":[12443,23645,6729,6731,23646,23649,23641,23644,9676,23647,23642,23648,23643],"class_list":["post-22664","post","type-post","status-publish","format-standard","hentry","category-medicines","category-s","tag-benefits-of-ipratropium-bromide","tag-benefits-of-sapimol","tag-ipratropium-bromide","tag-ipratropium-bromide-side-effects","tag-salbutamol-container","tag-salbutamol-container-side-effects","tag-sapimol","tag-sapimol-side-effects","tag-what-ipratropium-bromide-is-used-for","tag-what-is-salbutamol-container","tag-what-is-sapimol","tag-what-salbutamol-container-is-used-for","tag-what-sapimol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22664"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22664\/revisions"}],"predecessor-version":[{"id":22686,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22664\/revisions\/22686"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}