{"id":22517,"date":"2022-06-30T07:48:57","date_gmt":"2022-06-30T07:48:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22517"},"modified":"2022-07-01T10:51:17","modified_gmt":"2022-07-01T10:51:17","slug":"rukobia","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/rukobia\/","title":{"rendered":"Rukobia &#8211; Fostemsavir uses, dose and side effects"},"content":{"rendered":"\n<p>600 mg&nbsp;prolonged-release tablets&nbsp;are<br>fostemsavir<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Rukobia is and what it is used for<\/h2>\n\n\n\n<p>Rukobia contains fostemsavir and is a type of\u00a0HIV\u00a0medicine (antiretroviral medicine) called\u00a0<em>a\u00a0binding inhibitor<\/em>.\u00a0Rukobia works by binding to HIV\u00a0and\u00a0thus preventing it from entering\u00a0blood cells.<\/p>\n\n\n\n<p>Rukobia is used in combination with other antiretroviral medicines (&nbsp;<em>combination&nbsp;<\/em><em>therapy<\/em>&nbsp;) to treat HIV infection in adults with limited treatment options (other antiretroviral medicines are not effective enough or are not suitable).<\/p>\n\n\n\n<p>Rukobia does not cure HIV infection but it does reduce the amount of\u00a0virus\u00a0in the body and keeps it at a low level.\u00a0Because\u00a0HIV\u00a0reduces the number of CD4 cells in the body, a low level of\u00a0HIV\u00a0means that the number of CD4 cells in the blood increases.\u00a0CD4 cells are a type of\u00a0white blood cell\u00a0that is important for the body&#8217;s ability to fight\u00a0infections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Rukobia\u00a0<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Rukobia<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are\u00a0<strong>allergic to fostemsavir<\/strong>\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are taking any of these medicines:<ul><li><strong>carbamazepine<\/strong>\u00a0or\u00a0<strong>phenytoin\u00a0<\/strong>(used to treat\u00a0<strong>epilepsy<\/strong>\u00a0and prevent seizures)<\/li><li>mitotane\u00a0(for the treatment of several forms of\u00a0cancer\u00a0)<\/li><li>enzalutamide\u00a0(for the treatment of\u00a0prostate cancer\u00a0)<\/li><li>rifampicin\u00a0(for the treatment of certain\u00a0bacterial infections, such as\u00a0<strong>tuberculosis<\/strong>\u00a0)<\/li><li>medicines containing\u00a0<strong>St. John&#8217;s wort<\/strong>\u00a0(\u00a0<em>Hypericum perforatum<\/em>\u00a0) (a traditional herbal medicine used for\u00a0<strong>mild depression<\/strong>\u00a0and\u00a0<strong>mild anxiety<\/strong>\u00a0).<\/li><\/ul><\/li><li><strong>If you think any of these apply to you, do not take Rukobia<\/strong>\u00a0until you have talked to your doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Symptoms you need to be aware of<\/strong><\/p>\n\n\n\n<p>Some people who take medicines for HIV infection get other symptoms, which can be serious.&nbsp;These are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection\u00a0and\u00a0inflammation\u00a0_<\/li><li>joint pain, stiffness, and skeletal problems.<\/li><\/ul>\n\n\n\n<p>You need to know the important signs and symptoms to be aware of while taking Rukobia.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>See section 4 of this leaflet.<\/li><\/ul>\n\n\n\n<p><strong>Before taking&nbsp;&nbsp;<\/strong><strong>Rukobia, your doctor needs to know<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had\u00a0<strong>heart problems<\/strong>, or if you notice any abnormal changes in the heartbeat (eg too fast or too slow heartbeat).\u00a0Rukobia can affect the heart rhythm.<\/li><li>if you have or have had\u00a0<strong>liver disease,<\/strong>\u00a0including\u00a0hepatitis\u00a0B or\u00a0hepatitis\u00a0C.<\/li><li><strong>Talk to your doctor<\/strong>\u00a0if this applies to you.\u00a0You may need extra checks, including blood tests, while you are taking the medicine.<\/li><\/ul>\n\n\n\n<p><strong>You will need to submit blood samples regularly<\/strong><\/p>\n\n\n\n<p>As long as you are taking Rukobia, your doctor will arrange for regular blood tests to measure the amount of\u00a0HIV\u00a0in your blood and to check if you have any\u00a0side effects.\u00a0You will find more information about such\u00a0side effects\u00a0in\u00a0<strong>section 4<\/strong>\u00a0of this leaflet.<\/p>\n\n\n\n<p><strong>Keep in regular contact with your doctor<\/strong><\/p>\n\n\n\n<p>Rukobia helps to keep the HIV infection under control, but it does not cure the disease.&nbsp;You need to keep taking it every day to prevent the disease from getting worse.&nbsp;Because Rukobia does not cure HIV infection, you can still develop&nbsp;infections&nbsp;and diseases associated with HIV infection.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Keep in touch with your doctor and do not stop taking Rukobia unless your doctor advises <\/strong>you to do so.<\/li><\/ul>\n\n\n\n<p><strong>Protect others<\/strong><\/p>\n\n\n\n<p>HIV infection is spread through sexual contact with someone who is infected or by transmission via infected blood (eg if you use the same injection needles).&nbsp;Although effective&nbsp;antiretroviral&nbsp;therapy reduces the risk, you can still transmit HIV infection while taking this medicine.&nbsp;Discuss with your doctor what steps you need to take to avoid infecting others.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Rukobia is not recommended for patients under 18 years of age as it has not been studied in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Rukobia<\/h2>\n\n\n\n<p><strong>Tell your doctor or pharmacist<\/strong>\u00a0if you have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p><strong>Rukobia&nbsp;<\/strong>&nbsp;<strong>must not be taken with certain other medicines<\/strong><\/p>\n\n\n\n<p>Do not take Rukobia if you are taking any of these medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>carbamazepine<\/strong>\u00a0or\u00a0<strong>phenytoin<\/strong>\u00a0for the treatment of\u00a0<strong>epilepsy<\/strong>\u00a0and the prevention of seizures<\/li><li>mitotane\u00a0for the treatment of several forms of\u00a0cancer<\/li><li>enzalutamide\u00a0for the treatment of\u00a0prostate cancer<\/li><li>rifampicin\u00a0for the treatment of certain\u00a0bacterial infections, e.g.\u00a0<strong>tuberculosis<\/strong><\/li><li>products containing\u00a0<strong>St. John&#8217;s wort<\/strong>\u00a0(\u00a0<em>Hypericum perforatum<\/em>\u00a0) (a traditional herbal medicine used for\u00a0<strong>mild depression<\/strong>\u00a0and\u00a0<strong>mild anxiety<\/strong>\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>The following medicines are not recommended with Rukobia:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>elbasvir\/grazoprevir, for the treatment of\u00a0hepatitis\u00a0C\u00a0infection<strong>.<\/strong><\/li><li><strong>Tell your doctor or pharmacist<\/strong>\u00a0if you are being treated with any of these medicines.<\/li><\/ul>\n\n\n\n<p><strong>Some medicines may affect the effect of&nbsp;<\/strong><strong>Rukobia<\/strong><\/p>\n\n\n\n<p>or may increase the risk of\u00a0side effects.\u00a0Rukobia can also affect the effects of certain other medicines.<\/p>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if you are taking any of the medicines listed below:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>amiodarone,\u00a0disopyramide, ibutilide,\u00a0procainamide,\u00a0quinidine,\u00a0or sotalol, used to treat\u00a0heart problems<\/li><li>statins\u00a0(atorvastatin, fluvastatin, pitavastatin, rosuvastatin, or\u00a0simvastatin\u00a0), which are used to\u00a0lower cholesterol levels<\/li><li>ethinyl estradiol, which is used in\u00a0contraception<\/li><li>tenofoviralafenamide, which is used as antiviral medicine.<\/li><li><strong>Tell your doctor or pharmacist<\/strong>\u00a0if you are taking any of these medicines.\u00a0Your doctor may decide that\u00a0your dose\u00a0needs to be changed or that you need to have more check-ups.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>If you are\u00a0<strong>pregnant<\/strong>,\u00a0think you may be pregnant,\u00a0or\u00a0are planning to have a baby, ask your doctor for advice before taking Rukobia.\u00a0Your doctor\u00a0will discuss with you the benefits and risks for your baby if you are taking Rukobia during pregnancy.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p><strong>Women who are\u00a0HIV\u00a0-positive should not breastfeed<\/strong>\u00a0because the HIV infection can be transmitted to the baby via breast milk.\u00a0<\/p>\n\n\n\n<p><strong>It is not known<\/strong>&nbsp;whether the ingredients in Rukobia can pass into breast milk.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are breastfeeding or planning to breastfeed,\u00a0talk to a doctor immediately<strong>.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Rukobia makes you dizzy and has other\u00a0side effects\u00a0that diminish your attention.<\/p>\n\n\n\n<p>Do not drive or use machines unless you are sure that the medicine has no such effect on you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Rukobia<\/h2>\n\n\n\n<p><strong>Always take Rukobia exactly as your doctor has told you.&nbsp;<\/strong>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>The usual\u00a0dose<\/strong>\u00a0of Rukobia is a 600 mg tablet twice daily.<\/li><li><strong>The Rukobia tablets should be swallowed whole<\/strong>\u00a0with a little liquid.\u00a0<strong>Do not chew, crush or split the tablets<\/strong>\u00a0&#8211; if you do, there is a risk that the drug will be released too quickly in the body.<\/li><li>You can take Rukobia\u00a0<strong>with or without food<\/strong>.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Rukobia than you should<\/h2>\n\n\n\n<p>If you have taken too many Rukobia tablets,\u00a0<strong>contact your doctor or pharmacist<\/strong>.\u00a0Show them the package with Rukobia if possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Rukobia<\/h2>\n\n\n\n<p>Take it as soon as you remember.\u00a0However, if it is time for your next\u00a0dose, skip the missed\u00a0dose\u00a0and return to your regular schedule.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.\u00a0If you are not sure what to do,\u00a0<strong>ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Rukobia<\/h2>\n\n\n\n<p>Do not stop taking Rukobia without talking to a doctor.<\/p>\n\n\n\n<p>Take Rukobia for as long as your doctor recommends keeping your HIV infection under control and preventing the disease from getting worse.\u00a0Do not stop unless your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0<strong>It is therefore very important that you talk to your doctor about any changes in your health.<\/strong><\/p>\n\n\n\n<p><strong>Symptoms of&nbsp;infection&nbsp;and&nbsp;inflammation&nbsp;are common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<p>People with advanced HIV infection (\u00a0AIDS\u00a0) have a weak immune system and are more likely to get serious\u00a0<em>infections\u00a0<\/em>(\u00a0opportunistic\u00a0<em>infections\u00a0)<\/em>.\u00a0When they start treatment, the immune system becomes stronger and the body begins to fight\u00a0infection.<\/p>\n\n\n\n<p>Symptoms of&nbsp;infection&nbsp;and&nbsp;inflammation&nbsp;may develop, caused by:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>that old, hidden&nbsp;infections&nbsp;flare up again when the body fights them<\/li><li>that the immune system accidentally attacks healthy&nbsp;tissue&nbsp;(&nbsp;<em>autoimmune diseases<\/em>&nbsp;).<\/li><\/ul>\n\n\n\n<p>The symptoms of autoimmune diseases can develop several months after you start taking medicines for your HIV infection.<\/p>\n\n\n\n<p>The symptoms can be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>muscle weakness<\/strong>\u00a0and\/or\u00a0<strong>muscle pain<\/strong><\/li><li><strong>joint pain<\/strong>\u00a0or\u00a0<strong>joint swelling<\/strong><\/li><li><strong>weakness<\/strong>\u00a0that begins in the hands and feet and moves upwards towards the torso<\/li><li><strong>palpitations<\/strong>\u00a0or\u00a0<strong>tremors\u00a0<\/strong><em>_\u00a0_<\/em>\u00a0_\u00a0_\u00a0<em>_<\/em>\u00a0_<\/li><li><strong>excessive restlessness and excessive movements<\/strong>\u00a0(\u00a0<em>hyperactivity<\/em>\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>If you get symptoms of an\u00a0infection\u00a0or\u00a0inflammation<\/strong>, or if you notice any of the symptoms mentioned above:<\/p>\n\n\n\n<p><strong>Tell your doctor immediately<\/strong>.\u00a0Do not take other medicines for\u00a0infection\u00a0without talking to a doctor.<\/p>\n\n\n\n<p><strong>Very common&nbsp;<\/strong>side effects&nbsp;(may affect&nbsp;<strong>more than 1 in 10 people<\/strong>&nbsp;):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>diarrhea<\/li><li>vomiting<\/li><li>abdominal pain (\u00a0<em>abdominal pain<\/em>\u00a0)<\/li><li>headache<\/li><li>rash.<\/li><li><strong>Talk to your doctor<\/strong>\u00a0if you get any\u00a0side effects.<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;<\/strong>side effects&nbsp;(may affect&nbsp;<strong>up to 1 in 10 people<\/strong>&nbsp;):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>indigestion (\u00a0<em>dyspepsia<\/em>\u00a0)<\/li><li>lack of energy<\/li><li>cardiac arrhythmia is seen on\u00a0ECG\u00a0(\u00a0prolonged\u00a0\u00a0QT interval\u00a0)<\/li><li>muscle aches (\u00a0myalgia\u00a0)<\/li><li>drowsiness (\u00a0somnolence\u00a0)<\/li><li>dizziness<\/li><li>altered sense of taste (\u00a0dysgeusia\u00a0)<\/li><li>intestinal gases<\/li><li>difficulty sleeping (\u00a0insomnia\u00a0)<\/li><li>itching\u00a0(\u00a0pruritus\u00a0).<\/li><li>Talk to your doctor if you get any\u00a0side\u00a0effects.<\/li><\/ul>\n\n\n\n<p>Some&nbsp;side effects&nbsp;may only be seen in blood tests and may not occur immediately after you start taking Rukobia.<\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;that can show up in blood tests are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the increased amount of\u00a0enzymes\u00a0produced in the muscles (creatine phosphokinase, a sign of muscle damage)\u00a0<\/li><li>elevated\u00a0creatinine, an indicator of how well the kidneys are working<\/li><li>the increased amount of\u00a0enzymes\u00a0produced in the liver (increased\u00a0transaminases, a sign of liver damage).<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;that can show up in blood tests are:<\/strong><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have occurred in some people but it is not known how common they are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the increased amount of\u00a0bilirubin\u00a0(a substance produced by the liver) in the blood<\/li><\/ul>\n\n\n\n<p><strong>Joint pain, stiffness, and skeletal problems<\/strong><\/p>\n\n\n\n<p>Some people who take combination drugs for\u00a0HIV\u00a0suffer from a condition called\u00a0<em>osteonecrosis<\/em>.\u00a0Osteonecrosis\u00a0means that parts of the skeletal tissue die because the blood supply to the skeleton decreases.<\/p>\n\n\n\n<p>The risk of suffering from this increases in people who:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>treated for a long time with combination drugs<\/li><li>also, take anti-inflammatory drugs in the form\u00a0of\u00a0corticosteroids<\/li><li>drinking alcohol<\/li><li>has a very weak immune system<\/li><li>are overweight.<\/li><\/ul>\n\n\n\n<p><strong>Signs of&nbsp;osteonecrosis&nbsp;are:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stiffness in the joints<\/li><li>aches and pains (especially in hips, knees, or shoulders)<\/li><li>difficulty moving.<\/li><\/ul>\n\n\n\n<p>If you get any of these symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Tell your doctor.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Rukobia<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not take Rukobia after the expiry date which is stated on the carton and jar after \u201cEXP\u201d.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is fostemsavir.&nbsp;One tablet contains fostemsavir tromethamine equivalent to 600 mg fostemsavir.<\/li><li>The other ingredients are hydroxypropylcellulose, hypromellose,&nbsp;colloidal&nbsp;anhydrous silica, magnesium stearate, poly (vinyl alcohol), titanium dioxide (E171), macrogol 3350, talc, yellow iron oxide, red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Rukobia 600 mg\u00a0prolonged-release tablets\u00a0are beige, oval, biconvex tablets, approximately 19 mm long, 10 mm wide, and 8 mm thick, film-coated, and marked with the code &#8220;SV 1V7&#8221; on one side.<\/p>\n\n\n\n<p>Each pack consists of one or three cans containing 60&nbsp;prolonged-release tablets&nbsp;each.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>ViiV Healthcare BV<\/p>\n\n\n\n<p>Van Asch van Wijckstraat 55H<\/p>\n\n\n\n<p>3811 LP Amersfoort<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>GlaxoSmithKline Manufacturing SPA<br>Strada Provinciale Atlanta, 90<br>San Polo di Torrile<br>Parma, 43056<br>Italy<\/p>\n\n\n\n<p>For any information about this medicine, please contact the local representative of the Marketing Authorization Holder:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>ViiV Healthcare srl \/ bvTel: + 32 (0) 10 85 65 00<\/td><td><strong>Lithuania<\/strong>ViiV Healthcare BVTel: + 370 80000334<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>ViiV Healthcare BVTel: + 359 80018205<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>ViiV Healthcare srl \/ bvBelgium \/ BelgiumTel: + 32 (0) 10 85 65 00<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>GlaxoSmithKline, sroTel: + 420 222 001 111cz.info@gsk.com<\/td><td><strong>Hungary<\/strong>Healthcare BVTel .: + 36 80088309<\/td><\/tr><tr><td><strong>Denmark<\/strong>GlaxoSmithKline Pharma A \/ STel: + 45 36 35 91 00dk-info@gsk.com<\/td><td><strong>Malta<\/strong>Healthcare BVTel: + 356 80065004<\/td><\/tr><tr><td><strong>Germany<\/strong>ViiV Healthcare GmbHTel .: + 49 (0) 89 203 0038-10 viiv.med.info@viivhealthcare.com<\/td><td><strong>The Netherlands<\/strong>ViiV Healthcare BV&nbsp;Tel: + 31 (0) 33 2081199<\/td><\/tr><tr><td><strong>Eesti<\/strong>ViiV Healthcare BVTel: + 372 8002640estonia@gsk.com<\/td><td><strong>Norway<\/strong>GlaxoSmithKline ASTel: + 47 22 70 20 00<\/td><\/tr><tr><td><strong>Greece<\/strong>GlaxoSmithKline A\u03bf\u03bd\u03bf\u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03b7 AEBE:\u0397\u03bb: + 30 210 68 82 100<\/td><td><strong>Austria<\/strong>GlaxoSmithKline Pharma GmbHTel: + 43 (0) 1 97075 0at.info@gsk.com<\/td><\/tr><tr><td><strong>Spain<\/strong>Laboratorios ViiV Healthcare, SL Tel: + 34 900 923 501es-ci@viivhealthcare.com<\/td><td><strong>Poland<\/strong>GSK Services Sp.&nbsp;z ooTel .: + 48 (0) 22 576 9000<\/td><\/tr><tr><td><strong>France<\/strong>ViiV Healthcare SASTel .: + 33 (0) 1 39 17 69 69 Infomed@viivhealthcare.com<\/td><td><strong>Portugal<\/strong>VIIVHIV HEALTHCARE, UNIPESSOAL, LDATel: + 351 21 094 08 01 viiv.fi.pt@viivhealthcare.com<\/td><\/tr><tr><td><strong>Croatia<\/strong>ViiV Healthcare BVTel: + 385 800787089<\/td><td><strong>Romania<\/strong>ViiV Healthcare BVTel: + 40800672524<\/td><\/tr><tr><td><strong>Ireland<\/strong>GlaxoSmithKline (Ireland) LimitedTel: + 353 (0) 1 4955000<\/td><td><strong>Slovenia<\/strong>ViiV Healthcare BVTel: + 386 80688869<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovak Republic<\/strong>ViiV Healthcare BVTel: + 421 800500589<\/td><\/tr><tr><td><strong>Italy<\/strong>ViiV Healthcare Srl&nbsp;Tel: + 39 (0) 45 7741600<\/td><td><strong>Finland \/ Finland<\/strong>GlaxoSmithKline OyPuh \/ Tel: + 358 (0) 10 30 30 30Finland.tuoteinfo@gsk.com<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>ViiV Healthcare BV:\u0397\u03bb: + 357 80070017<\/td><td><strong>Sweden<\/strong>GlaxoSmithKline ABTel: + 46 (0) 8 638 93 00info.produkt@gsk.com<\/td><\/tr><tr><td><strong>Latvia<\/strong>ViiV Healthcare BVTel: + 371 80205045<\/td><td><strong>United Kingdom<\/strong><strong>(Northern Ireland)<\/strong>ViiV Healthcare BVTel: + 44 (0) 800 221441customercontactuk@gsk.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Rukobia contains fostemsavir and is a type of HIV medicine (antiretroviral medicine) called a binding inhibitor . Rukobia works by binding to the HIV virus and thus preventing it from entering blood cells .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[23460,23464,23463,23465,23469,23468,23462,23461,23466,23467],"class_list":["post-22517","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-fostemsavir","tag-fostemsavir-side-effects","tag-fostemsavir-tablet","tag-rukobia","tag-rukobia-side-effects","tag-rukobia-tablet","tag-what-fostemsavir-is-used-for","tag-what-is-fostemsavir","tag-what-is-rukobia","tag-what-rukobia-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22517"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22517\/revisions"}],"predecessor-version":[{"id":22543,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22517\/revisions\/22543"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22517"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22517"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}