{"id":22434,"date":"2022-06-28T11:45:21","date_gmt":"2022-06-28T11:45:21","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22434"},"modified":"2022-06-29T11:37:39","modified_gmt":"2022-06-29T11:37:39","slug":"ropivacain-fresenius-kabi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ropivacain-fresenius-kabi\/","title":{"rendered":"Ropivacaine Fresenius Kabi &#8211; Ropivacaine hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>2 mg \/ ml&nbsp;solution for infusion&nbsp;.<br>ropivacaine hydrochloride<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Ropivacaine Fresenius Kabi is and what it is used for<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Ropivacaine Fresenius Kabi contains the active substance ropivacaine hydrochloride.<\/li><li>It belongs to a group of medicines called local anesthetics.&nbsp;<\/li><\/ul>\n\n\n\n<p><strong>Ropivacaine Fresenius Kabi 2 mg\/ml\u00a0solution for\u00a0infusion<\/strong>\u00a0is used in adults and children of all ages for\u00a0acute\u00a0pain relief.\u00a0It numbs parts of the body, e.g.\u00a0after surgery.<\/p>\n\n\n\n<p>Ropivacaine hydrochloride contained in Ropivacaine Fresenius Kabi may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you get Ropivacaine Fresenius Kabi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not be given Ropivacaine Fresenius Kabi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are\u00a0<strong>allergic<\/strong>\u00a0(hypersensitive)\u00a0<strong>to\u00a0ropivacaine hydrochloride<\/strong>\u00a0or any of the other ingredients of this medicine (listed in section 6),<ul><li>If you are allergic to other\u00a0local anesthetics\u00a0within the same class (eg\u00a0lidocaine\u00a0or bupivacaine)<\/li><\/ul><\/li><li>if you have been told you have\u00a0low blood volume\u00a0(\u00a0hypovolemia\u00a0).<\/li><li>in a blood vessel\u00a0to numb a certain body part, or\u00a0<strong>in the cervix<\/strong>\u00a0to relieve labor pain.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before receiving Ropivacaine Fresenius Kabi if you are not sure if any of the above apply to you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Take special care to&nbsp;<strong>avoid&nbsp;injecting&nbsp;<\/strong>Ropivacaine Fresenius Kabi&nbsp;<strong>directly into a blood vessel<\/strong>&nbsp;to avoid direct toxic effects.&nbsp;The drug should not be administered in inflamed areas.<\/p>\n\n\n\n<p>Tell your doctor, nurse, or other healthcare professional before giving you Ropivacaine Fresenius Kabi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if your\u00a0<strong>general condition is bad<\/strong>\u00a0due to age or other factors,<\/li><li>if you have\u00a0<strong>heart problems<\/strong>\u00a0(partial or total\u00a0AV block\u00a0),<\/li><li>if you have severe\u00a0<strong>liver problems<\/strong>,\u00a0<\/li><li>if you have severe\u00a0kidney problems.\u00a0<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you have any of these problems as the&nbsp;dose&nbsp;of Ropivacaine Fresenius Kabi may need to be adjusted.<\/p>\n\n\n\n<p>Tell your doctor, nurse, or other healthcare professional before giving you Ropivacaine Fresenius Kabi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you suffer from&nbsp;<strong>acute&nbsp;porphyria<\/strong>&nbsp;(problems with the build-up of red blood pigments that in some cases cause neurological symptoms).&nbsp;<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you or someone in your family suffers from&nbsp;porphyria&nbsp;as another&nbsp;anesthetic&nbsp;may need to be used.&nbsp;<\/p>\n\n\n\n<p>Tell your doctor before treatment if you suffer from any diseases or medical conditions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Special care must be taken:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>In newborns because they are more susceptible to Ropivacaine Fresenius Kabi 2 mg\/ml solution for\u00a0infusion.<\/li><li>In children under 12 years of age, when\u00a0injecting\u00a0Ropivacaine Fresenius Kabi 2 mg\/ml solution for\u00a0infusion, a solution for numbing parts of the body has not been established in younger children.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ropivacaine Fresenius Kabi<\/h2>\n\n\n\n<p>Tell your doctor or healthcare professional if you have recently taken, or might take any other medicines.\u00a0This is because Ropivacaine Fresenius Kabi can affect the way some medicines work and some medicines can affect Ropivacaine Fresenius Kabi.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Other local anesthetics<\/strong>\u00a0<\/li><li><strong>Strong painkillers<\/strong>, e.g.\u00a0morphine or\u00a0codeine<\/li><li>Drugs used to treat irregular heartbeats\u00a0(\u00a0arrhythmia\u00a0), such as\u00a0lidocaine\u00a0and mexiletine.<\/li><\/ul>\n\n\n\n<p>Your doctor needs to know these medicines to be able to determine the right\u00a0dose\u00a0of Ropivacaine Fresenius Kabi for you.<\/p>\n\n\n\n<p>Also, tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Antidepressants<\/strong>&nbsp;(eg fluvoxamine)<\/li><li><strong>Antibiotics&nbsp;<\/strong>to treat&nbsp;infections&nbsp;caused by bacteria (such as enoxacin).<\/li><\/ul>\n\n\n\n<p>This is because your body will take longer to get rid of Ropivacaine Fresenius Kabi if you take these medicines.&nbsp;If you are taking any of these medicines, long-term use of Ropivacaine Fresenius Kabi should be avoided<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0It is not known whether ropivacaine has effects during pregnancy or is excreted in human milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Ropivacaine Fresenius Kabi may make you feel drowsy and may affect your ability to react.\u00a0Do not drive or use any tools or machines until the day after you receive Ropivacaine Fresenius Kabi.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ropivacaine Fresenius Kabi contains sodium chloride<\/h2>\n\n\n\n<p>This medicine contains 3.4 mg of sodium (the main ingredient in table salt\/table salt) per ml.\u00a0This corresponds to 0.17% of the recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Ropivacaine Fresenius Kabi<\/h2>\n\n\n\n<p>Ropivacaine Fresenius Kabi will be given to you by a doctor.\u00a0The\u00a0dose\u00a0that your doctor gives you depends on the type of pain relief you need.\u00a0It also depends on your body size, age, and physical condition.<\/p>\n\n\n\n<p>Ropivacaine Fresenius Kabi is given to you as an\u00a0infusion.\u00a0Which part of the body it should be used for depends on why you are getting Ropivacaine Fresenius Kabi.\u00a0Your doctor will give you Ropivacaine Fresenius Kabi in one of the following places:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The part of the body that needs to be anesthetized.<\/li><li>Close to the part of the body that needs to be anesthetized.<\/li><li>In an area away from the part of the body that needs to be anesthetized.&nbsp;This is the case if you are given an&nbsp;epidural&nbsp;infusion&nbsp;(in the area around the spine).<\/li><\/ul>\n\n\n\n<p>When Ropivacaine Fresenius Kabi is used in one of these places, the nerves are stopped from being able to send pain messages to the brain.\u00a0It stops feelings of pain, heat, or cold in the area where it is used but you may still have other feelings such as pressure or touch.<\/p>\n\n\n\n<p>Your doctor will know which place is the right one to give you this medicine.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>Dose\u00a0one depends on what the medicine is used for and also on your health, age, and weight.<\/p>\n\n\n\n<p><strong>Processing time<\/strong><\/p>\n\n\n\n<p>Administration&nbsp;of ropivacaine normally lasts&nbsp;<strong>between 0.5 and 6 hours<\/strong>&nbsp;but can last for&nbsp;<strong>up to 72 hours<\/strong>&nbsp;for&nbsp;<strong>pain relief<\/strong>&nbsp;during or after surgery.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Ropivacaine Fresenius Kabi than you should;<\/h2>\n\n\n\n<p>Serious\u00a0side effects\u00a0are from ingesting too much Ropivacaine Fresenius Kabi needs special treatment and your doctor is trained to deal with these situations.\u00a0The first signs if you have been given too much Ropivacaine Fresenius Kabi are usually the following<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hearing and vision problems,<\/li><li>numbness of the lip, tongue, and around the mouth,<\/li><li>dizziness and intoxication,<\/li><li>knitting,<\/li><li>speech disorders characterized by poor articulation (\u00a0dysarthria\u00a0),<\/li><li>muscle stiffness, muscle twitching, seizures,<\/li><li>low\u00a0blood pressure,<\/li><li>slow or irregular heartbeat.<\/li><\/ul>\n\n\n\n<p>These symptoms may precede cardiac arrest, respiratory arrest, or severe seizures.<\/p>\n\n\n\n<p>To reduce the risk of serious\u00a0side effects, your doctor will stop giving you Ropivacaine Fresenius Kabi as soon as these signs appear.\u00a0This means that if any of these happen to you, or if you think you have been given too much Ropivacaine Fresenius Kabi<strong>, tell your doctor and healthcare professional immediately.<\/strong><\/p>\n\n\n\n<p>Serious\u00a0side effects\u00a0from giving too much Ropivacaine Fresenius Kabi include difficulty speaking, muscle twitching, tremors, tremors, seizures, and unconsciousness.<\/p>\n\n\n\n<p>Talk to a doctor or healthcare professional if you notice any of the above symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Important&nbsp;side effects&nbsp;are to be aware of:<\/strong><\/p>\n\n\n\n<p>Sudden\u00a0<strong>life-threatening allergic reactions<\/strong>\u00a0(eg\u00a0anaphylaxis\u00a0) are rare and may affect up to 1 in 1,000 people.\u00a0Possible symptoms include<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sudden onset of rash,\u00a0<\/li><li>an itchy or lumpy rash (hives),\u00a0<\/li><li>swelling of the face, lips, tongue, or other parts of the body,\u00a0<\/li><li>shortness of breath, wheezing, or difficulty breathing.<\/li><\/ul>\n\n\n\n<p><strong>If you think that Ropivacaine<\/strong> Fresenius Kabi gives you an\u00a0allergic reaction<strong>, tell your doctor or healthcare professional immediately.<\/strong><\/p>\n\n\n\n<p><strong>Other possible side effects:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;).&nbsp;This can make you feel dizzy and faint.<\/li><li>Nausea<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tingling and numbness (\u00a0paresthesia\u00a0),<\/li><li>Dizziness<\/li><li>Headache<\/li><li>Slow or fast heartbeat (\u00a0bradycardia,\u00a0tachycardia\u00a0)<\/li><li>High\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0)<\/li><li>Vomiting<\/li><li>Difficulty urinating (\u00a0urinary retention\u00a0)<\/li><li>Fever or chills<\/li><li>Stiffness<\/li><li>Back pain<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Concern<\/li><li>Decreased sensitivity or sensation in the skin<\/li><li>Fainting<\/li><li>Breathing difficulties<\/li><li>Low body temperature (&nbsp;hypothermia&nbsp;)<\/li><li>Some symptoms may occur if one&nbsp;injection&nbsp;was accidentally given into a blood vessel or if you have been given too much Ropivacaine Fresenius Kabi (see section 3 above, \u201cIf you have been given too much Ropivacaine Fresenius Kabi\u201d).&nbsp;Symptoms include seizures (cramps), dizziness or intoxication, numbness in the lips and around the mouth, numbness in the tongue, hearing problems, vision problems, speech disorders, muscle stiffness, tremors<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart attack (cardiac arrest)<\/li><li>Uneven heart rhythm (&nbsp;arrhythmia&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;include:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Numbness due to nerve irritation caused by the needle or\u00a0injection.\u00a0This is usually not for a long time.<\/li><li>Involuntary muscle movements (\u00a0dyskinesia\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Possible\u00a0side effects\u00a0that have been observed with other local anesthetics and that can also be caused by Ropivacaine Fresenius Kabi include:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nerve damage.&nbsp;These can in rare cases (may occur in up to 1 in 1000 users) cause permanent discomfort.<\/li><li>If too much Ropivacaine Fresenius Kabi is given in the spinal fluid, the whole body may be anesthetized.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>In children, the\u00a0side effects\u00a0are the same as in adults, except for low\u00a0blood pressure\u00a0which occurs less frequently in children (may occur in up to 1 in 10 children), and vomiting which occurs more often in children (may occur in more than 1 in 10 children).<\/p>\n\n\n\n<p><strong>Reporting of side effects<\/strong><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor or nurse.&nbsp;This also applies to side effects that are not mentioned in this information. You can also report side effects directly (see details below).&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n\n\n\n<p>www.lakemedelsverket.se<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Ropivacaine Fresenius Kabi<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Ropivacaine Fresenius Kabi should be used before the expiry date which is stated on the sachet and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p>Do not use Ropivacaine Fresenius Kabi if a&nbsp;precipitate&nbsp;appears in the infusion solution.<\/p>\n\n\n\n<p>Your doctor or hospital will normally store Ropivacaine Fresenius Kabi and will be responsible for the quality of the opened product that is not used immediately.\u00a0They are also responsible for ensuring that unused Ropivacaine Fresenius Kabi is disposed of properly.<\/p>\n\n\n\n<p>The medicine should not be disposed of via wastewater or household waste.\u00a0The doctor, nurse, or pharmacist will take care of medicines that are no longer needed.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ropivacaine 2 mg\/ml.\u00a0One 100 ml bag contains 200 mg of ropivacaine (in the form of hydrochloride). A 200 ml bag contains 400 mg of ropivacaine (in the form of hydrochloride).<\/li><li>The other ingredients are sodium chloride,\u00a0hydrochloric acid\u00a0(for\u00a0pH\u00a0adjustment), sodium hydroxide (for\u00a0pH\u00a0adjustment), and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Ropivacaine Fresenius Kabi solution for\u00a0infusion\u00a0is a clear, colorless\u00a0solution for infusion.<\/p>\n\n\n\n<p>Ropivacaine Fresenius Kabi 2 mg\/ml solution for\u00a0infusion\u00a0is supplied in 100 ml and 200 ml transparent plastic bags.<\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<p>1 bag with an outer bag<\/p>\n\n\n\n<p>5 bags with outer bag<\/p>\n\n\n\n<p>10 bags with outer bag<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorization Holder:<\/em><\/p>\n\n\n\n<p>Fresenius Kabi AB<\/p>\n\n\n\n<p>751 74 Uppsala<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Fresenius Kabi Norge AS<\/p>\n\n\n\n<p>PO Box 430<\/p>\n\n\n\n<p>N-1753 Halden<\/p>\n\n\n\n<p>Norway<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2 mg \/ ml solution for infusion .<br \/>\nropivacaine hydrochloride<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[23376,18435,23372,23375,18431,18434,23373,18432,23374,18433],"class_list":["post-22434","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-ropivacaine-fresenius-kabi","tag-benefits-of-ropivacaine-hydrochloride","tag-ropivacaine-fresenius-kabi","tag-ropivacaine-fresenius-kabi-side-effects","tag-ropivacaine-hydrochloride","tag-ropivacaine-hydrochloride-side-effects","tag-what-is-ropivacaine-fresenius-kabi","tag-what-is-ropivacaine-hydrochloride","tag-what-ropivacaine-fresenius-kabi-is-used-for","tag-what-ropivacaine-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22434"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22434\/revisions"}],"predecessor-version":[{"id":22505,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22434\/revisions\/22505"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}