{"id":22356,"date":"2022-06-25T06:25:43","date_gmt":"2022-06-25T06:25:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22356"},"modified":"2022-06-25T09:35:29","modified_gmt":"2022-06-25T09:35:29","slug":"roclanda","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/roclanda\/","title":{"rendered":"Roclanda &#8211; Latanoprost and netarsudil uses, dose and side effects"},"content":{"rendered":"\n<p>50 micrograms \/ ml + 200 micrograms \/ ml&nbsp;eye drops&nbsp;, solution<br>latanoprost + netarsudil<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Roclanda is and what it is used for<\/h2>\n\n\n\n<p>Roclanda contains the active substances latanoprost and netarsudil.\u00a0Latanoprost belongs to a group of medicines called\u00a0prostaglandin analogs.\u00a0Netarsudil belongs to a group of medicines called Rho-kinase inhibitors.\u00a0They work in different ways to reduce the amount of fluid in the eyes and thus lower the pressure.<\/p>\n\n\n\n<p>Roclanda is used to lower the pressure in the eyes of adults who have an eye disease called\u00a0glaucoma\u00a0or who have elevated pressure in the eyes.\u00a0If the pressure in the eye is too high, vision can be damaged.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Roclanda<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Roclanda<\/h2>\n\n\n\n<p>if you are allergic to latanoprost or netarsudil or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>If you think any of the following may be true for you, talk to your doctor or pharmacist before using Roclanda:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have dry eyes.<\/li><li>You have severe\u00a0asthma\u00a0or\u00a0asthma\u00a0that is not well controlled.<\/li><li>You have had or have an ongoing viral infection in your eye caused by the\u00a0herpes\u00a0simplex\u00a0virus.<\/li><\/ul>\n\n\n\n<p>Do not use Roclanda more than once a day, as it may give you more\u00a0side effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Roclanda should not be used in children or adolescents under 18 years of age, as it is not known if the medicine is safe and effective in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Roclanda<\/h2>\n\n\n\n<p>Roclanda can affect or be affected by other medicines.\u00a0Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, especially those containing another\u00a0prostaglandin analog, such as latanoprost.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0Do not use Roclanda if you are pregnant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Shortly after using Roclanda, you may notice that your vision becomes blurred or abnormal.&nbsp;Do not drive or use machines until your vision problems have passed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Roclanda contains benzalkonium chloride<\/h2>\n\n\n\n<p>This medicine contains benzalkonium chloride, which can be absorbed by soft contact lenses and discolor them.\u00a0Remove the contact lenses before using the medicine and wait at least 15 minutes before re-inserting them.<\/p>\n\n\n\n<p>Benzalkonium chloride can also be irritating to the eyes, especially if you have dry eyes or problems with the cornea (the clear membrane at the front of the eye).\u00a0If you experience irritation, tingling, or pain in the eye after using this medicine, consult a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Roclanda<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Roclanda should only be used in the eyes (&nbsp;ocular&nbsp;use).<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one drop in the affected eye once a day in the evening.&nbsp;Use the medicine at about the same time each day.&nbsp;Do not use this medicine more than once a day.<\/p>\n\n\n\n<p><strong>How to use the medicine<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20191122000031#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/0e8f380b-71e1-421d-8c35-f6b9eb915770\" alt=\"picture 1\" title=\"picture 1\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Wash your hands before you start.<\/li><li>Do not touch the drip tip with your fingers when opening or closing the bottle.\u00a0This can contaminate the eye drops.<\/li><li>Unscrew the bottle cap and place the cap on its side on a clean surface.\u00a0Continue to hold the bottle while making sure that the drip tip does not touch anything.<\/li><li>Hold the bottle, pointing down, between your thumb and fingers.<\/li><li>Bend your head back.<\/li><li>Pull down the lower eyelid with a clean finger until a &#8220;pocket&#8221; is formed between the eyelid and the eye.\u00a0The drop should end up here.<\/li><li>Move the drip tip towards the eye.\u00a0Do this in front of a mirror if it makes it easier.<\/li><li>Do not touch the eye or eyelid, surrounding areas, or other surfaces with the drip tip.\u00a0This can contaminate the eye drops.<\/li><li>Gently press the bottle to release a drop of Roclanda into the eye.<\/li><li>Only one drop should be applied to the eye each time.\u00a0If a drop misses the eye, try again.<\/li><li>After\u00a0dosing, press a finger against the inner corner of the eye at the nose.\u00a0Hold your finger for 1 minute and close your eyes at all times.<\/li><li>If you need to use drops in both eyes, repeat the steps for the other eye while the bottle is open.<\/li><li>Replace the bottle cap and close the bottle.<\/li><li>Put the bottle back in the carton to protect the eye drops from light until you need to use them again.<\/li><\/ul>\n\n\n\n<p>If you use other\u00a0eye drops, wait at least 5 minutes after using them, and only then use Roclanda.\u00a0If you use an eye ointment, use it last.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Roclanda than you should&nbsp;<\/h2>\n\n\n\n<p>Rinse the eye with lukewarm water.\u00a0Do not take more drops, but wait until it is time for the next regular\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Roclanda<\/h2>\n\n\n\n<p>Continue with the next\u00a0dose\u00a0as planned.\u00a0Do not use a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>Do not use more than one drop in the affected eye once a day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Roclanda<\/h2>\n\n\n\n<p>Do not stop taking Roclanda without talking to your doctor first.\u00a0If you stop using Roclanda, the pressure in your eye will not be kept under control, which may lead to impaired vision\/loss of vision.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been seen with Roclanda and other medicines containing latanoprost or netarsudil alone.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Very common (may affect more than 1 user in 10)<\/strong><ul><li><em>Effects on<\/em> the eye<ul><li>Reddening of the eyes;\u00a0small deposits in the front of the eye and pain where the drops have been applied;\u00a0a gradually increasing amount of brown pigment in the colored part of the eye (\u00a0iris\u00a0) which gives a change in eye color;\u00a0a gradual increase in eyelash color (darker), length, thickness, and number.<\/li><\/ul><\/li><\/ul><\/li><li>Common (may affect up to 1 in 10 people)<ul><li>Effects on the eye<ul><li>Infection\u00a0or\u00a0inflammation\u00a0of the eye;\u00a0dry eyes or small damage to the liquid film on the surface of the eye;\u00a0eye secretions;\u00a0itchy eyelids;\u00a0cloudiness of the eye and slight deterioration of vision;\u00a0eye pain;\u00a0a feeling of grit or of having something in the eye;\u00a0general redness of the eyes shortly after application of the drops;\u00a0redness of the eyes in the form of dots or spots;\u00a0conjunctivitis\u00a0(eye inflammation or prominent blood vessels) caused by an allergic reaction;\u00a0watery eyes, increased sensitivity to light;\u00a0swelling around the eye;\u00a0crusting on the eyelids;\u00a0dimsyn.<\/li><\/ul><\/li><li>General\u00a0adverse\u00a0reactions<ul><li>Redness\u00a0or\u00a0itching\u00a0of the skin on the face.<\/li><\/ul><\/li><\/ul><\/li><li>Uncommon (may affect up to 1 in 100 people)<ul><li>Effects on the eye<ul><li>Increased fluid pressure inside the eye;\u00a0inflammation\u00a0of the colored part of the eye (\u00a0iris\u00a0);\u00a0swollen iris;\u00a0increased creasing of the clear membrane over the eye where it meets the lower eyelid;\u00a0blindness, blurred vision, double vision or halo effect;\u00a0blocked tear duct;\u00a0small colored dots\/spots on the surface of the eye;\u00a0dry eyelids;\u00a0dry eyes due to\u00a0inflammation\u00a0of the eyelid glands;\u00a0eye allergy;\u00a0shiny\/glossy eyes;\u00a0tired eyes;\u00a0a numb or burning sensation in the eye;\u00a0abnormal outward turning of the lower eyelid;\u00a0loss of\u00a0eyelashes, an eye disease associated with\u00a0diabetes<\/li><\/ul><\/li><li>Side effects\u00a0are in other parts of the body<ul><li>Nasal congestion;\u00a0nosebleeds;\u00a0discomfort and pain in the nose;\u00a0headache;\u00a0dizziness;\u00a0redness\u00a0or\u00a0itching\u00a0of the skin;\u00a0dry skin;\u00a0thickening of the skin;\u00a0muscle pain or cramps;\u00a0joint pain;\u00a0jaw pain;\u00a0tingling in the skin;\u00a0bronchitis;\u00a0chest pain (angina);\u00a0awareness of heartbeat (palpitations);\u00a0asthma;\u00a0shortness of breath (\u00a0dyspnoea\u00a0).<\/li><\/ul><\/li><\/ul><\/li><li>Rare\u00a0side effects\u00a0(may affect up to 1 in 1,000 people)<ul><li>Effects on the eye<ul><li>Swelling or abrasions with damage to the eye surface;\u00a0swelling around the eye (periorbital\u00a0edema\u00a0);\u00a0the eyelashes\u00a0growing in the wrong direction or an extra row of\u00a0eyelashes\u00a0is formed;\u00a0scarring on the surface of the eye;\u00a0fluid-filled area within the colored part of the eye (iris cyst);\u00a0skin reactions on the eyelids;\u00a0darkening of the skin on the eyelids;\u00a0viral infection of the eye caused by the\u00a0herpes\u00a0simplex\u00a0virus\u00a0(\u00a0HSV\u00a0).<\/li><\/ul><\/li><li>Side effects\u00a0are in other parts of the body<ul><li>Exacerbated asthma;\u00a0severe itchy skin.<\/li><\/ul><\/li><\/ul><\/li><li>Very rare\u00a0side effects\u00a0(may affect up to 1 in 10,000 people)<ul><li>Effects on<em> the eye<\/em><ul><li>The eyes look sick (deepening of the eye socket).<\/li><\/ul><\/li><li><em>Side effects\u00a0are in other parts of the body<\/em><ul><li>Exacerbated angina in patients who also have heart disease.<\/li><\/ul><\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Roclanda<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle and carton after \u201cEXP\u201d or \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Unopened bottle: Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/p>\n\n\n\n<p>After opening the bottle: Do not store it above 25 \u00b0 C.<\/p>\n\n\n\n<p>Store in the original package.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>To prevent\u00a0infection, discard the bottle 4 weeks after it was first opened and use a new bottle instead.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are latanoprost and netarsudil.\u00a0Each ml of solution contains 50 micrograms of latanoprost and 200 micrograms netarsudil (as mesylate).<\/li><li>Other excipients are benzalkonium chloride (see section 2 under \u201cRoclanda contains benzalkonium chloride\u201d), mannitol, boric acid, sodium hydroxide (for\u00a0pH\u00a0adjustment), and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Roclanda&nbsp;eye drops&nbsp;are a clear solution in a plastic bottle.&nbsp;Each bottle contains 2.5 ml of medicine and each pack contains a bottle with a screw cap.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Niittyhaankatu 20, 33720 Tampere, Finland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Aerie Pharmaceuticals Ireland, Limited<\/p>\n\n\n\n<p>Athlone Business and Technology Park, Dublin Road,<\/p>\n\n\n\n<p>Garrycastle, Athlone, Co Westmeath, N37 DW40, Ireland<\/p>\n\n\n\n<p>and<\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Kelloportinkatu 1, 33100 Tampere, Finland<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Santen OyTel: +32 (0) 24019172<\/td><td><strong>Lithuania<\/strong>Santen OyTel: +370 37 366628<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Santen OyTel: +359 (0) 888 755 393<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>Santen OyTel: +352 (0) 27862006<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Santen OyTel: +420 234 102 170<\/td><td><strong>Hungary<\/strong>Santen OyTel: +36 (06) 16777305<\/td><\/tr><tr><td><strong>Denmark<\/strong>Santen OyTel: +45 78737843<\/td><td><strong>Malta<\/strong>Santen OyTel: + 358 (0) 3 284 8111<\/td><\/tr><tr><td><strong>Germany<\/strong>Santen GmbHTel: +49 (0) 3030809610<\/td><td><strong>The Netherlands<\/strong>Santen OyTel: +31 (0) 207139206<\/td><\/tr><tr><td><strong>Eesti<\/strong>Santen OyTel: +372 5067559<\/td><td><strong>Norway<\/strong>SantenPharma ABTel: +47 21939612<\/td><\/tr><tr><td><strong>Greece<\/strong>Santen Oy:\u0397\u03bb: + 358 (0) 3 284 8111<\/td><td><strong>Austria<\/strong>Santen OyTel: +43 (0) 720116199<\/td><\/tr><tr><td><strong>Spain<\/strong>Santen Pharmaceutical Spain SLTel: + 34 914 142 485<\/td><td><strong>Poland<\/strong>Santen OyTel .: +48 (0) 221168608<\/td><\/tr><tr><td><strong>France<\/strong>SantenTel: +33 (0) 1 70 75 26 84<\/td><td><strong>Portugal<\/strong>Santen OyTel: + 351 308 805 912<\/td><\/tr><tr><td><strong>Croatia<\/strong>Santen OyTel: + 358 (0) 3 284 8111<strong>Ireland<\/strong>Santen UK LimitedTel: + 353 (0) 16950008<\/td><td><strong>Romania<\/strong>Santen OyTel: +40 (0) 316300603<strong>Slovenia<\/strong>Santen OyTel: + 358 (0) 3 284 8111<\/td><\/tr><tr><td><strong>Iceland<\/strong>Santen OyPhone: + 358 (0) 3 284 8111<\/td><td><strong>Slovak Republic<\/strong>Santen OyTel: +421 (01) 23 332 5519<\/td><\/tr><tr><td><strong>Italy<\/strong>Santen Italy SrlTel: +39 0236009983<\/td><td><strong>Finland \/ Finland<\/strong>Santen OyPuh \/ Tel: +358 (0) 974790211<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>Santen Oy:\u0397\u03bb: + 358 (0) 3 284 8111<\/td><td><strong>Sweden<\/strong>Santen OyTel: +46 (0) 850598833<\/td><\/tr><tr><td><strong>Latvia<\/strong>Santen OyTel: +371 677 917 80<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Santen UK LimitedTel: + 44 (0) 845 075 4863<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Roclanda contains the active substances latanoprost and netarsudil. Latanoprost belongs to a group of medicines called prostaglandin analogues . Netarsudil belongs to a group of medicines called Rho-kinase inhibitors. They work in different ways to reduce the amount of fluid in the eyes and thus lower the pressure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[15448,15451,23018,23022,23253,23256,15449,23019,23254,15450,23020,23255],"class_list":["post-22356","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-latanoprost","tag-latanoprost-side-effects","tag-netarsudil","tag-netarsudil-side-effects","tag-roclanda","tag-roclanda-side-effects","tag-what-is-latanoprost","tag-what-is-netarsudil","tag-what-is-roclanda","tag-what-latanoprost-is-used-for","tag-what-netarsudil-is-used-for","tag-what-roclanda-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22356","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22356"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22356\/revisions"}],"predecessor-version":[{"id":22381,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22356\/revisions\/22381"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22356"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22356"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22356"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}