{"id":22202,"date":"2022-06-22T07:24:25","date_gmt":"2022-06-22T07:24:25","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22202"},"modified":"2022-06-22T10:05:53","modified_gmt":"2022-06-22T10:05:53","slug":"rinvoq","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/rinvoq\/","title":{"rendered":"RINVOQ &#8211; Upadacitinib uses, dose and side effects"},"content":{"rendered":"\n<p>15 mg and 30 mg&nbsp;prolonged-release tablets&nbsp;are<br>Upadacitinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What RINVOQ is and what it is used for<\/h2>\n\n\n\n<p>RINVOQ contains the active substance upadacitinib.\u00a0It belongs to a group of medicines called Januskinas inhibitors.\u00a0By lowering the activity of an\u00a0enzyme\u00a0in the body called &#8216;Janus kinase&#8217;, RINVOQ helps reduce\u00a0inflammation\u00a0in the following diseases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rheumatoid arthritis<\/li><li>psoriatic arthritis<\/li><li>ankylosing spondylitis<\/li><li>atopic&nbsp;dermatitis<\/li><\/ul>\n\n\n\n<p><em>Rheumatoid arthritis<\/em><\/p>\n\n\n\n<p>RINVOQ is used to treat adults with\u00a0rheumatoid arthritis\u00a0(\u00a0rheumatoid arthritis\u00a0).\u00a0Rheumatoid arthritis\u00a0is a disease that causes inflamed joints.\u00a0If you have moderate to severely active\u00a0rheumatoid arthritis, you may first be given other medicines, which are usually methotrexate.\u00a0If these medicines do not work well enough, you will receive RINVOQ either alone or in combination with methotrexate to treat your\u00a0rheumatoid arthritis.<\/p>\n\n\n\n<p>RINVOQ can help reduce pain, stiffness, and swelling in your joints, reduce fatigue and slow down damage to bones and\u00a0cartilage\u00a0in your joints.\u00a0These effects can make it easier for you to perform everyday activities and thus improve your quality of life.<\/p>\n\n\n\n<p><em>Psoriatic arthritis<\/em><\/p>\n\n\n\n<p>RINVOQ is used to treat adults with psoriatic arthritis.\u00a0Psoriatic arthritis is a disease that causes inflamed joints and\u00a0psoriasis.\u00a0If you have active psoriatic arthritis, you may first be given other medicines.\u00a0If these medicines do not work well enough, you will be given RINVOQ either alone or in combination with methotrexate to treat your psoriatic arthritis.<\/p>\n\n\n\n<p>RINVOQ can help reduce pain, stiffness, and swelling in and around the joints, pain, stiffness in the spine, psoriasis rash, and fatigue.\u00a0It can slow down damage to the bones and\u00a0cartilage\u00a0in your joints.\u00a0These effects can make it easier for you to perform everyday activities and thus improve your quality of life.<\/p>\n\n\n\n<p><em>Ankylosing spondylitis<\/em><\/p>\n\n\n\n<p>RINVOQ is used to treat adults with\u00a0ankylosing spondylitis.\u00a0Ankylosing spondylitis\u00a0is a disease that mainly causes\u00a0inflammation\u00a0in the spine.\u00a0If you have active\u00a0ankylosing spondylitis, you may first be given other medicines.\u00a0If these medicines do not work well enough, you will be given RINVOQ to treat your\u00a0ankylosing spondylitis.<\/p>\n\n\n\n<p><br>RINVOQ can help reduce back pain, stiffness, and\u00a0inflammation\u00a0in the spine.\u00a0These effects can make it easier for you to perform everyday activities and thus improve your quality of life.<\/p>\n\n\n\n<p><em>Atopic&nbsp;dermatitis<\/em><\/p>\n\n\n\n<p>RINVOQ is used to treat adults and adolescents aged 12 years and older with moderate to severe atopic\u00a0dermatitis, also called\u00a0atopic eczema\u00a0and flexural eczema.\u00a0RINVOQ can be used with eczema medicines that you apply to the skin or use alone.<\/p>\n\n\n\n<p>RINVOQ can improve the condition of the skin and reduce\u00a0itching\u00a0and flare-ups.\u00a0RINVOQ can also relieve the symptoms of pain, anxiety, and depression that people with atopic\u00a0dermatitis\u00a0can have.\u00a0RINVOQ can also reduce sleep disorders and provide an improved quality of life.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking RINVOQ\u00a0<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take RINVOQ<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to upadacitinib or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have a serious&nbsp;infection&nbsp;(such as&nbsp;pneumonia&nbsp;or a bacterial skin infection)<\/li><li>if you have active&nbsp;tuberculosis&nbsp;(TB)<\/li><li>if you have severe liver problems<\/li><li>if you are pregnant (see section Pregnancy, breast-feeding and contraception)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before and during treatment with RINVOQ about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have an\u00a0infection\u00a0(fever, sweating or chills, shortness of breath, have hot, red, or sore skin or sores on the body, feeling tired, coughing, burning sensation when urinating or urinating more often than normal, have a severe headache with neck stiffness), or if you have had a recurring\u00a0infection\u00a0&#8211; RINVOQ may reduce the body&#8217;s ability to fight\u00a0infection\u00a0and thus aggravate an ongoing\u00a0infection\u00a0or increase the risk of getting a new infection<\/li><li>you have had\u00a0tuberculosis\u00a0or been in close contact with someone with\u00a0tuberculosis.\u00a0Your doctor will test you for\u00a0tuberculosis\u00a0before you start taking RINVOQ and may repeat the test during treatment<\/li><li>if you have had a\u00a0herpes\u00a0zoster\u00a0infection\u00a0(\u00a0shingles\u00a0) because RINVOQ may cause it to come back.\u00a0Tell your doctor if you get painful skin rashes with blisters as this may be a sign of\u00a0shingles<\/li><li>you have had\u00a0hepatitis\u00a0B or C<\/li><li>you have recently or are planning to get vaccinated &#8211; this is because live vaccines are not recommended when using RINVOQ<\/li><li>if you have cancer &#8211; because your doctor needs to assess if you can still take RINVOQ<\/li><li>you are at high risk of developing skin cancer.\u00a0Your doctor may recommend preventative measures such as regular skin examinations while you are taking RINVOQ.\u00a0Tell your doctor if you develop a new skin change or see any change in the appearance of your skin.\u00a0Some patients receiving RINVOQ have developed skin cancer<\/li><li>you have heart problems, high\u00a0blood pressure,\u00a0or high\u00a0cholesterol<\/li><li>your liver is not working as well as it should<\/li><li>you have had blood clots in the veins of your legs (deep\u00a0vein thrombosis\u00a0) or your lungs (\u00a0pulmonary embolism\u00a0).\u00a0Tell your doctor if you get a sore, swollen leg, chest pain, or shortness of breath as this may be a sign of blood clots in the veins.<\/li><li>you have kidney problems<\/li><li>you have had\u00a0diverticulitis\u00a0(a type of\u00a0inflammation\u00a0of the colon) (see section 4).<\/li><\/ul>\n\n\n\n<p>If you notice any of the following serious\u00a0side effects, tell your doctor straight away:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe abdominal pain, especially if accompanied by fever, nausea, and vomiting.<\/li><\/ul>\n\n\n\n<p><strong>Blood tests<\/strong><\/p>\n\n\n\n<p>You will have a blood test before you start taking RINVOQ or while you are taking it.\u00a0This is to check if you have a low\u00a0red blood cell count\u00a0(\u00a0anemia\u00a0), low\u00a0white blood cell count\u00a0(\u00a0neutropenia\u00a0or lymphopenia), high blood fats (\u00a0cholesterol\u00a0), or high levels of liver enzymes.\u00a0These tests are to check that the treatment with RINVOQ does not cause any problems.<\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>Infection rates are higher in patients 65 years of age and older.\u00a0Tell your doctor as soon as you notice any signs or symptoms of an\u00a0infection.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>RINVOQ is not recommended for children under 12 years of age or adolescents weighing less than 30 kg with atopic\u00a0dermatitis.\u00a0This is because the drug has not been studied in these patients.<\/p>\n\n\n\n<p>RINVOQ is not recommended for children and adolescents under 18 years of age with\u00a0rheumatoid arthritis, psoriatic arthritis, or\u00a0ankylosing spondylitis.\u00a0This is because the drug has not been studied in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and RINVOQ<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This is because some medicines may reduce the effect of RINVOQ or increase the risk of\u00a0side effects.\u00a0You must tell your doctor or pharmacist if you are taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines for fungal infections (eg itraconazole, posaconazole or voriconazole)<\/li><li>drugs against bacterial infections (eg clarithromycin)<\/li><li>medicines for Cushing&#8217;s syndrome (eg\u00a0ketoconazole\u00a0)<\/li><li>drugs against\u00a0tuberculosis\u00a0(eg rifampicin)<\/li><li>medicines for seizures and seizures (eg\u00a0phenytoin\u00a0)<\/li><li>medicines that affect your immune system (eg azathioprine, cyclosporin, and tacrolimus)<\/li><li>drugs that may increase the risk of\u00a0diverticulitis, such as non-steroidal anti-inflammatory drugs (often used as painkillers and\/or to treat\u00a0inflammation\u00a0in muscles or joints) and\/or\u00a0opioids\u00a0(used for severe pain), and\/or\u00a0corticosteroids\u00a0(often used to treat\u00a0inflammation\u00a0) (see section 4).<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you or you are not sure, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and contraception<\/h2>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>RINVOQ should not be used if you are pregnant.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>If you are breastfeeding or planning to start breastfeeding, talk to your doctor before using this medicine.\u00a0You should not take RINVOQ while breastfeeding as it is unknown if this medicine passes into breast milk.\u00a0You and your doctor should decide whether to breastfeed or take RINVOQ.\u00a0You should not do both.<\/p>\n\n\n\n<p><em>Contraceptive<\/em><\/p>\n\n\n\n<p>If you are a woman of\u00a0childbearing potential, you must use an effective contraceptive to avoid pregnancy while you are being treated with RINVOQ and for at least 4 weeks after the last\u00a0dose\u00a0of RINVOQ.\u00a0If you become pregnant during this time, you must tell your doctor immediately.<\/p>\n\n\n\n<p>If your child gets her first period while taking RINVOQ, tell your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>RINVOQ does not affect the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take RINVOQ<\/h2>\n\n\n\n<p><strong>Always take this medicine exactly as your doctor or pharmacist has told you.<\/strong><\/p>\n\n\n\n<p>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>How much to take<\/strong><\/p>\n\n\n\n<p><em>If you have\u00a0rheumatoid arthritis<\/em>, psoriatic arthritis,<em> and\u00a0ankylosing spondylitis<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one 15 mg tablet once a day.<\/p>\n\n\n\n<p><em>If you have atopic&nbsp;dermatitis<\/em><\/p>\n\n\n\n<p><em>Adults<\/em>&nbsp;:<\/p>\n\n\n\n<p>The recommended\u00a0dose\u00a0is 15 mg or 30 mg as prescribed by your doctor,\u00a0which is taken as a tablet once a day.<\/p>\n\n\n\n<p>Your doctor may increase or decrease your&nbsp;dose&nbsp;depending on how well the medicine works.<\/p>\n\n\n\n<p><em>Older:<\/em><\/p>\n\n\n\n<p>If you are 65 years of age or older, the recommended&nbsp;dose&nbsp;is 15 mg once daily.<\/p>\n\n\n\n<p><em>Adolescents (from 12 to 17 years) weighing at least 30 kg:<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one 15 mg tablet once a day.<\/p>\n\n\n\n<p><strong>How to take the medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the tablet whole with water.\u00a0The tablet should not be split, crushed, chewed, or broken before swallowing as it may affect the amount of RINVOQ in your body.<\/li><li>To help you remember to take RINVOQ, take it at the same time each day.<\/li><li>The tablets can be taken with or without food.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more RINVOQ than you should<\/h2>\n\n\n\n<p>If you take more RINVOQ than you should, contact your doctor.&nbsp;You may experience some of the&nbsp;side effects&nbsp;described in section 4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take RINVOQ<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you miss a\u00a0dose, take it as soon as you remember.<\/li><li>If you have missed your\u00a0dose\u00a0for an entire day, skip the missed\u00a0dose\u00a0and take your usual\u00a0dose,\u00a0as usual, the next day.<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a forgotten tablet.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking RINVOQ<\/h2>\n\n\n\n<p>Do not stop taking RINVOQ unless your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Contact your doctor or seek medical help immediately if you get any signs\/symptoms of\u00a0infection\u00a0eg:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>shingles\u00a0or painful skin rash with blisters (\u00a0herpes\u00a0zoster) &#8211; common (may affect up to 1 in 10 people)<\/li><li>lung infection\u00a0(\u00a0pneumonia\u00a0) which can cause shortness of breath, fever, and cough &#8211; uncommon (may affect up to 1 in 100 people)<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you get any of the following side effects:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the infection\u00a0you in the throat and nose<\/li><li>acne<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cough<\/li><li>fever<\/li><li>cold sores (\u00a0herpes\u00a0simplex)<\/li><li>nausea<\/li><li>increase in an\u00a0enzyme\u00a0called creatine kinase, which is shown in blood tests<\/li><li>the low number of\u00a0white blood cells\u00a0shown in blood samples<\/li><li>elevated cholesterol levels (a type of blood fat) shown in blood tests<\/li><li>elevated levels of liver enzymes, which appear on blood tests (signs of liver problems)<\/li><li>weight gain<\/li><li>inflammation\u00a0(swelling) of the hair follicles<\/li><li>influenza<\/li><li>anemia<\/li><li>abdominal pain<\/li><li>fatigue<\/li><li>headache<\/li><li>hives<\/li><li>urinary tract infection<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fungus in the mouth (white spots in the mouth)<\/li><li>elevated triglyceride levels (a type of blood fat) shown in blood tests<\/li><li>diverticulitis&nbsp;(painful&nbsp;inflammation&nbsp;in small pockets in the intestinal mucosa)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store RINVOQ<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister and carton after \u201cEXP\u201d.<\/p>\n\n\n\n<p>No special temperature instructions.<\/p>\n\n\n\n<p>Store in original blister.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is upadacitinib.<\/p>\n\n\n\n<p><strong>RINVOQ 15 mg&nbsp;prolonged-release tablet&nbsp;is<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Each\u00a0prolonged-release tablet\u00a0contains upadacitinib hemihydrate, equivalent to 15 mg upadacitinib.<\/li><li>Other ingredients are:<ul><li>Tablet core: microcrystalline cellulose, mannitol, tartaric acid, hypromellose, silicon\u00a0colloidal, anhydrous, magnesium stearate<\/li><li>Film coating: poly (vinyl alcohol), macrogol, talc, titanium dioxide (E171), red iron oxide (E172), black iron oxide (E172).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>RINVOQ 30 mg&nbsp;prolonged-release tablet&nbsp;is<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Each\u00a0prolonged-release tablet\u00a0contains upadacitinib hemihydrate, equivalent to 30 mg upadacitinib.<\/li><li>Other ingredients are:<ul><li>Tablet core: microcrystalline cellulose, mannitol, tartaric acid, hypromellose, silicon\u00a0colloidal, anhydrous, magnesium stearate<\/li><li>Film coating: poly (vinyl alcohol), macrogol, talc, titanium dioxide (E171), red iron oxide (E172).<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p><strong>RINVOQ 15 mg&nbsp;prolonged-release tablet&nbsp;is<\/strong><\/p>\n\n\n\n<p>RINVOQ 15 mg&nbsp;prolonged-release tablets&nbsp;are purple, oval, biconvex tablets debossed with \u201ca15\u201d on one side.<\/p>\n\n\n\n<p>The tablets are available in blister packs or jars.<\/p>\n\n\n\n<p>RINVOQ is available in packs of 28 or 98\u00a0prolonged-release tablets\u00a0and multipacks of 84, consisting of 3 cartons containing 28\u00a0prolonged-release tablets\u00a0each.<\/p>\n\n\n\n<p>Each calendar blister contains 7 tablets.<\/p>\n\n\n\n<p>RINVOQ is available in cans of desiccant containing 30\u00a0prolonged-release tablets, each pack contains 1 can (pack of 30 tablets) or 3 cans (pack of 90 tablets).<\/p>\n\n\n\n<p><strong>RINVOQ 30 mg&nbsp;prolonged-release tablet&nbsp;is<\/strong><\/p>\n\n\n\n<p>RINVOQ 30 mg&nbsp;prolonged-release tablets&nbsp;are red, oval, biconvex tablets debossed with \u201ca30\u201d on one side.<\/p>\n\n\n\n<p>The tablets are available in blister packs or jars.<\/p>\n\n\n\n<p>RINVOQ is available in packs of 28 or 98\u00a0prolonged-release tablets.<\/p>\n\n\n\n<p>Each calendar blister contains 7 tablets.<\/p>\n\n\n\n<p>RINVOQ is available in cans of desiccant containing 30\u00a0prolonged-release tablets, each pack contains 1 can (pack of 30 tablets) or 3 cans (pack of 90 tablets).<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>AbbVie Deutschland GmbH &amp; Co.&nbsp;KG<\/p>\n\n\n\n<p>Knollstrasse<\/p>\n\n\n\n<p>67061 Ludwigshafen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>AbbVie Srl<\/p>\n\n\n\n<p>SR 148 Pontina, km 52 SNC<\/p>\n\n\n\n<p>04011 Campoverde di Aprilia (Latina)<\/p>\n\n\n\n<p>Italy<\/p>\n\n\n\n<p>AbbVie Logistics BV<\/p>\n\n\n\n<p>Zuiderzeelaan 53<\/p>\n\n\n\n<p>Zwolle, 8017 JV, The Netherlands<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<p>AbbVie AB<\/p>\n\n\n\n<p>Tel: +46 (0) 8 684 44 600<\/p>\n","protected":false},"excerpt":{"rendered":"<p>RINVOQ contains the active substance upadacitinib. It belongs to a group of medicines called Januskinas inhibitors. By lowering the activity of an enzyme in the body called &#8216;januskinas&#8217;, RINVOQ helps reduce inflammation in the following diseases:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[23138,23142,23141,23133,23137,23136,23139,23134,23140,23135],"class_list":["post-22202","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-rinvoq","tag-rinvoq-side-effects","tag-rinvoq-tablet","tag-upadacitinib","tag-upadacitinib-side-effects","tag-upadacitinib-tablet","tag-what-is-rinvoq","tag-what-is-upadacitinib","tag-what-rinvoq-is-used-for","tag-what-upadacitinib-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22202"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22202\/revisions"}],"predecessor-version":[{"id":22237,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22202\/revisions\/22237"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22202"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22202"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}