150 mg \/ 75 mg \/ 400 mg Film-coated tablet<\/p>\n\n\n\n
The active substances are rifampicin,\u00a0isoniazid,\u00a0and pyrazinamide.\u00a0Each tablet contains 150 mg rifampicin, 75 mg\u00a0isoniazid\u00a0and 400 mg pyrazinamide.<\/p>\n\n\n\n
Other ingredients are:<\/p>\n\n\n\n
Tablet core: pregelatinized maize starch, maize starch, sodium lauryl sulfate, crospovidone, magnesium stearate, talc.<\/p>\n\n\n\n
Film coating: copovidone, hypromellose, talc, titanium dioxide (E171), opadry pink 03B54929 [hypromellose, titanium dioxide (E171), macrogol 400, red iron oxide (E172)], opadry clear OY-S-29019 [hypromellose, macrogol 6000].<\/p>\n\n\n\n
Sandoz A \/ S<\/p>\n\n\n\n
Edvard Thomsens Vej 14<\/p>\n\n\n\n
2300 Copenhagen S<\/p>\n\n\n\n
Denmark<\/p>\n\n\n\n
Rimcure tablets are oval, pink, and film-coated.<\/p>\n\n\n\n
Rimcure tablets are supplied in blister packs.<\/p>\n\n\n\n
Rimcure belongs to the group of antituberculosis drugs.\u00a0It is a combination drug consisting of three very effective antituberculosis drugs that stop the growth of mycobacteria.\u00a0These mycobacteria cause\u00a0tuberculosis.<\/p>\n\n\n\n
Rimcure is used for the first phase of the treatment of\u00a0tuberculosis.<\/p>\n\n\n\n
\u2022 if you are allergic (hypersensitive) to<\/p>\n\n\n\n
rifamycins,\u00a0isoniazid, pyrazinamide<\/p>\n\n\n\n
– any of the other ingredients in Rimcure.<\/p>\n\n\n\n
\u2022 if you have acute\u00a0liver disease or have previously had a liver disease caused by a medicine.<\/p>\n\n\n\n
\u2022 if you have a condition called\u00a0porphyria.<\/p>\n\n\n\n
\u2022 if you have\u00a0acute\u00a0gout.<\/p>\n\n\n\n
\u2022 if you suffer from severe renal impairment.<\/p>\n\n\n\n
\u2022 if you are taking any of the following medicines:<\/p>\n\n\n\n
– voriconazole.<\/p>\n\n\n\n
– protease inhibitors, other than ritonavir, if you are being treated with a maximum\u00a0dose\u00a0of 600 mg twice daily.<\/p>\n\n\n\n
Do not take Rimcure if the above applies to you.<\/p>\n\n\n\n
Talk to your doctor or pharmacist if you are unsure about anything<\/p>\n\n\n\n
Tell your doctor if you have had any of the following conditions before using this medicine:<\/p>\n\n\n\n
\u2022 impaired liver function and chronic liver disease<\/p>\n\n\n\n
\u2022 impaired renal function<\/p>\n\n\n\n
\u2022 gout<\/p>\n\n\n\n
\u2022 diabetes<\/p>\n\n\n\n
\u2022 epilepsy<\/p>\n\n\n\n
\u2022 inflammation of the peripheral nerves<\/p>\n\n\n\n
\u2022 eye diseases<\/p>\n\n\n\n
\u2022 chronic alcoholism<\/p>\n\n\n\n
\u2022 malnutrition<\/p>\n\n\n\n
You should not use Rimcure if your body weight is below 30 kg.<\/p>\n\n\n\n
You should not stop taking Rimcure without consulting your doctor.<\/p>\n\n\n\n
You should use an extra non-hormonal contraceptive in addition to birth control pills while you are being treated<\/p>\n\n\n\n
Rimcure.<\/p>\n\n\n\n
You should not drink alcohol while taking Rimcure.<\/p>\n\n\n\n
Avoid foods that are high in tyramine (such as cheese and red wine) or\u00a0histamine\u00a0(such as tuna).\u00a0These can, during treatment with Rimcure, cause\u00a0side effects\u00a0such as headaches, palpitations, and redness of the skin.<\/p>\n\n\n\n
Take this medicine at least one hour before a meal.<\/p>\n\n\n\n
Tell your doctor as soon as possible if you are pregnant or think you may be pregnant. Your doctor will decide if it is appropriate to continue treatment with Rimcure. If you are taking Rimcure during pregnancy, your doctor should give you vitamin B6 during pregnancy and vitamin K during the last month of pregnancy.<\/p>\n\n\n\n
This medicine passes into breast milk, so do not use Rimcure while breastfeeding.\u00a0You must tell your doctor if you are breastfeeding or planning to breastfeed before taking Rimcure.<\/p>\n\n\n\n
Rimcure can cause\u00a0side effects\u00a0such as dizziness, confusion, and cloudy eyesight.\u00a0The ability to drive or use machines may be impaired when using Rimcure.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects\u00a0.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n
Tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n
You should not use Rimcure with the following medicines:<\/p>\n\n\n\n
\u2022 voriconazole<\/p>\n\n\n\n
\u2022 protease inhibitors, except ritonavir if you are being treated with a maximum\u00a0dose\u00a0of 600 mg twice daily<\/p>\n\n\n\n
You should not use Rimcure with the following medicines:<\/p>\n\n\n\n
\u2022 nevirapine<\/p>\n\n\n\n
\u2022 simvastatin<\/p>\n\n\n\n
Ritonavir<\/p>\n\n\n\n
\u2022 birth control pills . You should use an extra non-hormonal contraceptive during treatment with Rimcure.<\/p>\n\n\n\n
Also, tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n
\u2022\u00a0Drugs for irregular heartbeat<\/strong>\u00a0such as class 1A\u00a0antiarrhythmics\u00a0(\u00a0quinidine,\u00a0disopyramide\u00a0),\u00a0propafenone, mexiletine<\/p>\n\n\n\n \u2022\u00a0Medicines for the heart or\u00a0blood pressure\u00a0et<\/strong>: calcium antagonists, carvedilol,\u00a0digoxin, beta-blocker\u00a0blockers (such as\u00a0metoprolol, propranolol), imidapril<\/p>\n\n\n\n \u2022 Immunosuppressive drugs such as ciclosporin, tacrolimus, sirolimus ,<\/strong><\/p>\n\n\n\n \u2022 Corticosteroids are<\/strong><\/p>\n\n\n\n \u2022\u00a0Medicines for\u00a0infection\u00a0such<\/strong>\u00a0as azole-type\u00a0antifungals, terbinafine, clarithromycin, telithromycin, dapsone, atovaquone, chloramphenicol, linezolid<\/p>\n\n\n\n \u2022 Drugs<\/strong> such as haloperidol , benzodiazepines, tricyclic antidepressants, buspirone, clozapine<\/p>\n\n\n\n \u2022 Medicines that prevent blood clots<\/strong> such as oral anticoagulants , warfarin<\/p>\n\n\n\n Hormone\u00a0therapy<\/strong>\u00a0such as gestrinone,\u00a0estrogen,\u00a0and progestagen given as hormone replacement therapy and thyroid hormones<\/p>\n\n\n\n \u2022 Painkillers<\/strong> such as morphine, etoricoxib, rofecoxib<\/p>\n\n\n\n \u2022 AIDS<\/strong> medicines <\/strong>such as efavirenz, zidovudine, nevirapine, stavudine<\/p>\n\n\n\n \u2022\u00a0Epilepsy\u00a0medicines\u00a0<\/strong>such as tiagabine, carbamazepine,\u00a0phenytoin, ethosuximide<\/p>\n\n\n\n \u2022 Medicines for insomnia<\/strong> such as zolpidem, zaleplon<\/p>\n\n\n\n \u2022 Medicines for asthma <\/strong>such as theophylline<\/p>\n\n\n\n \u2022\u00a0Diabetes\u00a0drugs such as repaglinide<\/strong>\u00a0or sulfonamide-type oral antidiabetics<\/p>\n\n\n\n \u2022 p-aminosalicylic acid<\/strong> (a medicine used to treat tuberculosis and inflammatory bowel disease)<\/p>\n\n\n\n \u2022 Methadone<\/strong> (a drug used for heroin addicts)<\/p>\n\n\n\n