{"id":22103,"date":"2022-06-18T07:54:59","date_gmt":"2022-06-18T07:54:59","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22103"},"modified":"2022-06-18T12:23:03","modified_gmt":"2022-06-18T12:23:03","slug":"rigmin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/rigmin\/","title":{"rendered":"Rigmin &#8211; Rivastigmine uses, dose and side effects"},"content":{"rendered":"\n<p>4.6 mg \/ 24 h, 9.5 mg \/ 24 h&nbsp;transdermal<br>patch rivastigmine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Rigmin is and what it is used for<\/h2>\n\n\n\n<p>The active substance in Rigmin transdermal patch is rivastigmine.<\/p>\n\n\n\n<p>Rivastigmine belongs to a class of substances called cholinesterase inhibitors.\u00a0In patients with\u00a0Alzheimer&#8217;s dementia, certain nerve cells in the brain die.\u00a0This leads to low levels of the neurotransmitter\u00a0acetylcholine\u00a0(a substance that allows nerve cells to communicate with each other).\u00a0Rivastigmine works by blocking the\u00a0enzymes\u00a0that break down\u00a0acetylcholine\u00a0(\u00a0acetylcholinesterase\u00a0and butyrylcholinesterase).\u00a0By blocking these\u00a0enzymes, Rigmin increases acetylcholine levels in the brain, thus helping to reduce the symptoms of\u00a0Alzheimer&#8217;s disease.<\/p>\n\n\n\n<p>Rigmin is used to treat adult patients with mild to moderate\u00a0Alzheimer&#8217;s dementia, a progressive brain disease that gradually affects memory, intellectual ability, and behavior.<\/p>\n\n\n\n<p>Rivastigmine contained in Rigmin may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Rigmin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Rigmin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to rivastigmine (the active substance in Rigmin) or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have ever had an\u00a0allergic reaction\u00a0to a similar type of medicine (carbamate derivatives).<\/li><li>if you get a skin reaction that spreads beyond the size of the patch, if a more intense local reaction occurs (eg blisters, increasing skin inflammation, swelling), and if it does not improve within 48 hours after removal of the transdermal patch.<\/li><\/ul>\n\n\n\n<p>If this applies to you, talk to your doctor and do not use Rigmin transdermal\u00a0patches.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Rigmin transdermal patches:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have ever had, an irregular or slow heartbeat.<\/li><li>if you have or have ever had, an active\u00a0stomach ulcer.<\/li><li>if you have or have ever had, difficulty urinating.<\/li><li>if you have or have ever had seizures.<\/li><li>if you have or have ever had,\u00a0asthma\u00a0or severe respiratory problems.<\/li><li>if you suffer from tremors.<\/li><li>if you have a low body weight.<\/li><li>if you get reactions from the stomach or intestines such as.\u00a0nausea, vomiting, and diarrhea.\u00a0You may become dehydrated (lose too much fluid) if vomiting or diarrhea persists for a long time.<\/li><li>if you have impaired liver function.<\/li><\/ul>\n\n\n\n<p>If any of the above applies to you, your doctor may need to check you more closely when you are being treated with this medicine.<\/p>\n\n\n\n<p>If you have not used a&nbsp;patch&nbsp;for more than three days, do not put on a new one until you have talked to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>There is no relevant use of Rigmin for a\u00a0pediatric\u00a0population in the treatment of\u00a0Alzheimer&#8217;s disease.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Rigmin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Rigmin can affect other anticholinergic medicines, some of which are medicines for stomach cramps or seizures (eg dicyclomine), medicines to treat\u00a0Parkinson&#8217;s disease\u00a0(eg amantadine), or medicines to prevent motion sickness (eg diphenhydramine, scopolamine, or meclozine).<\/p>\n\n\n\n<p>Rigmin&nbsp;patches&nbsp;should not be given concomitantly with metoclopramide (a medicine used to relieve or prevent nausea or vomiting).&nbsp;Taking both medicines at the same time can cause problems such as&nbsp;stiff joints or tremors in the hands.<\/p>\n\n\n\n<p>If you are going to have surgery while using Rigmin transdermal\u00a0patches, tell your doctor that you are using the medicine, as Rigmin\u00a0transdermal patches\u00a0may intensify the effects of certain muscle relaxants during anesthesia.<\/p>\n\n\n\n<p>Caution should be exercised when taking Rigmin\u00a0patches\u00a0concomitantly with beta-blockers\u00a0(medicines such as atenolol for high\u00a0blood pressure, angina, and other heart conditions).\u00a0Taking both medicines at the same time can cause problems such as\u00a0a slower heartbeat (\u00a0bradycardia\u00a0), which can lead to fainting or unconsciousness.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>If you are pregnant, the benefits of using Rigmin must be weighed against the possible effects on your unborn baby.\u00a0Rigmin should not be used during pregnancy unless necessary.<\/p>\n\n\n\n<p>You should not breastfeed when you are being treated with Rigmin\u00a0transdermal patches.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Your doctor will tell you if you can drive and use machines safely when you have this disease.&nbsp;Rigmin transdermal&nbsp;patches&nbsp;can cause fainting spells or you may feel very confused.&nbsp;If you feel dizzy or confused, do not drive, use machines or perform any other tasks that require your attention.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Rigmin<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.\u00a0If you are not sure, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<p><strong>IMPORTANT:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Remove the previous day&#8217;s\u00a0patches\u00a0before putting ONE new\u00a0patch.<\/strong><\/li><li><strong>Use only one\u00a0patch\u00a0per day.<\/strong><\/li><li><strong>Do not cut the patch into pieces.<\/strong><\/li><li><strong>The patch should be pressed firmly with the palm of your hand for at least 30 seconds.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>How to start the treatment<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor will tell you which Rigmin\u00a0transdermal patch\u00a0is most suitable for you.<\/li><li>Treatment is usually started with Rigmin 4.6 mg \/ 24 hours.<\/li><li>The usual recommended daily\u00a0dose\u00a0is Rigmin 9.5 mg \/ 24 hours per day.\u00a0If this\u00a0dose\u00a0is well-tolerated, your doctor may increase your\u00a0dose\u00a0to Rigmin 13.3 mg \/ 24 hours.<\/li><li>Use only one Rigmin\u00a0patch\u00a0at a time and replace the patch with a new one after 24 hours.<\/li><\/ul>\n\n\n\n<p>During treatment, your doctor may need to adjust your&nbsp;dose&nbsp;to suit your individual needs.<\/p>\n\n\n\n<p>If you have not used a&nbsp;patch&nbsp;in three days, do not put on the next&nbsp;patch&nbsp;until you have talked to your doctor.&nbsp;The treatment with&nbsp;transdermal patches&nbsp;can be resumed with the same&nbsp;dose&nbsp;if the treatment has only been interrupted for a maximum of three days.&nbsp;Otherwise, your doctor will restart your treatment with Rigmin 4.6 mg \/ 24 hours.<\/p>\n\n\n\n<p>Rigmin can be used with food, drink, and alcohol.<\/p>\n\n\n\n<p><strong>Where should your Rigmin&nbsp;transdermal patch&nbsp;be affixed?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Before applying the patch, make sure that the skin is clean, dry, and hair-free, free of powder, oil, moisturizer, or lotion, which may prevent the patch from adhering properly to the skin, free from scratches, rashes, and\/or irritation.<\/li><li>If you are already using\u00a0patches, remove what you are wearing before applying a new one.\u00a0If you have several\u00a0patches\u00a0attached to your body at the same time, you may receive an overdose\u00a0of\u00a0the medicine, which can be potentially dangerous.<\/li><li>Apply\u00a0ONE\u00a0patch\u00a0per day in\u00a0ONLY ONE\u00a0of the possible locations shown in the following diagram:<ul><li>left upper arm\u00a0or\u00a0right upper arm<\/li><li>the left\u00a0or\u00a0right side of the upper part of the chest\u00a0(avoid the breasts themselves)<\/li><li>the left\u00a0or\u00a0right side of the upper back<\/li><li>the left\u00a0<strong>or<\/strong>\u00a0right side of the lower back<\/li><\/ul><\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Remove the previous day&#8217;s&nbsp;patch&nbsp;after 24 hours before putting ONE new&nbsp;patch&nbsp;in ONLY ONE of the following possible places.<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a>When changing\u00a0patches, you must remove the previous day&#8217;s\u00a0patch\u00a0before applying the new patch to a new spot on the skin each time (eg on the right side of the body one day, on the left side the next day, on the upper part of the body one day, on the lower part of the body the next day).\u00a0Do not put a new\u00a0patch\u00a0on the same skin surface twice within 14 days.<\/p>\n\n\n\n<p><strong>How should your Rigmin&nbsp;transdermal patch&nbsp;be attached?<\/strong><\/p>\n\n\n\n<p>Rigmin\u00a0patches\u00a0are thin, opaque plastic patches that are attached to the skin.\u00a0Each\u00a0patch\u00a0is sealed in a patch envelope, which protects it until it is put on.\u00a0Do not open the patch envelope or remove the patch until just before you apply it.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>If you are already using\u00a0patches, carefully remove what you are wearing before applying a new one.<br>For patients starting treatment for the first time or starting Rigmin again after stopping treatment, please start at the next picture.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>Each\u00a0patch\u00a0is individually packaged in a sealed patch envelope. Only open the patch envelope when you are ready to apply the patch. Cut up the patch envelope along the dotted line and remove the patch from the patch envelope.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>A protective film covers the adhesive side of the patch. Peel off one side of the protective film and do not touch the adhesive part of the patch with your fingers.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>Attach the adhesive side of the patch to the upper or lower part of the back, upper arm, or chest, and then pull off the other part of the protective film.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>Then press the patch firmly in place for at least 30 seconds with the palm of your hand and make sure that the edges adhere properly.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20121215000037#\" rel=\"noopener\"><\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>If it is helpful, you can write e.g.&nbsp;what a weekday it is with a thin ballpoint pen on the patch.<\/p>\n\n\n\n<p>The patch should be used all the time until it is time to change to a new one.\u00a0Feel free to try to find different places to attach the patches, places that feel comfortable for you, and where the clothes do not rub against the patch.<\/p>\n\n\n\n<p><strong>How to remove your Rigmin\u00a0transdermal patch?<\/strong><\/p>\n\n\n\n<p>Gently grasp one edge of the patch and slowly pull it away from the skin.&nbsp;If adhesive remains on the skin, you can moisten the area with warm water and mild soap or use baby oil to remove them.&nbsp;Alcohol or other dissolving liquids (nail polish remover or other solvents) should not be used.<\/p>\n\n\n\n<p>You should wash your hands with soap and water when the patch has been removed.&nbsp;If the patch comes in contact with the eyes, or if the eyes turn red after handling the patch, rinse immediately with plenty of water and consult a physician if symptoms persist.<\/p>\n\n\n\n<p><strong>Can you use your Rigmin transdermal\u00a0patch\u00a0when bathing, swimming, or sunbathing?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bathing, swimming, or showering should not affect the patch.\u00a0Make sure that the patch does not come off on such occasions.<\/li><li>Do not expose the patch to external heat sources (eg excessive sunbathing, sauna, solarium) for a long time.<\/li><\/ul>\n\n\n\n<p><strong>What to do if Rigmin transdermal&nbsp;patches&nbsp;fall off?<\/strong><\/p>\n\n\n\n<p>If a&nbsp;patch&nbsp;falls off, apply a new one for the rest of the day, then change to a new one again at the usual time the next day.<\/p>\n\n\n\n<p><strong>When and for how long should you use your Rigmin\u00a0transdermal patch?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>To benefit from your treatment, you need to put on a new&nbsp;patch&nbsp;every day, preferably at the same time every day.<\/li><li>Use only one&nbsp;patch&nbsp;at a time and replace the patch with a new one after 24 hours.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Rigmin than you should<\/h2>\n\n\n\n<p>If you inadvertently apply more than one\u00a0patch, remove all patches from the skin and tell your doctor that you accidentally applied more than one\u00a0patch.\u00a0You may need medical attention.\u00a0Some people, who have inadvertently used too much Rigmin, have felt nauseous, vomited, or had diarrhea, high\u00a0blood pressure, and hallucinations.\u00a0Slow heart rate and fainting can also occur.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Rigmin<\/h2>\n\n\n\n<p>If you find that you have forgotten to apply a\u00a0patch, apply a new one immediately.\u00a0You can apply the next\u00a0patch\u00a0at the usual time the next day.\u00a0Do not apply two\u00a0patches\u00a0to compensate for a forgotten\u00a0patch.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Rigmin<\/h2>\n\n\n\n<p>If you stop using the patch, talk to your doctor or pharmacist.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n<p>You will likely experience some\u00a0side effects, especially when you start treatment or when your\u00a0dose\u00a0is increased.\u00a0Usually, the\u00a0side effects\u00a0gradually disappear when the body gets used to the drug.<\/p>\n\n\n\n<p><strong>Remove the patch and contact your doctor immediately if you get any of the following&nbsp;side effects&nbsp;that may be serious:<\/strong><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Loss of appetite<\/li><li>Dizziness<\/li><li>The feeling of agitation or fatigue<\/li><li>Urinary incontinence (inability to retain urine)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart rhythm disorders (both fast and slow heartbeats)<\/li><li>Seeing things that are not real (hallucinations)<\/li><li>Gastric ulcer<\/li><li>Dehydration (fluid loss)<\/li><li>Hyperactivity (high activity, restlessness)<\/li><li>Aggressiveness<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Case<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stiffness in arms or legs<\/li><li>Shaking hands<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>\u00a0(occurs in an unknown number of users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An allergic reactions\u00a0where the patch has been applied, such as\u00a0blisters or inflammation of the skin<\/li><li>Worsening of the symptoms of\u00a0Parkinson&#8217;s disease\u00a0&#8211; such as\u00a0trembling, stiffness, and sluggish gait<\/li><li>Inflammation\u00a0of the pancreas &#8211; symptoms include severe pain in the upper abdomen, usually with nausea and vomiting)<\/li><li>Fast or irregular heartbeat<\/li><li>High\u00a0blood pressure<\/li><li>Cramps (seizures)<\/li><li>Disorders of liver function (yellowing of the skin, yellowing of the whites of the eyes, abnormally dark urine or unexplained nausea, unexplained vomiting, tiredness, and loss of appetite)<\/li><li>Elevated liver values<\/li><li>Feeling of restlessness<\/li><li>Nightmares<\/li><\/ul>\n\n\n\n<p>Remove the patch and contact your doctor immediately if you get any of the above\u00a0side effects.<\/p>\n\n\n\n<p><strong>Additional&nbsp;side effects&nbsp;that have been seen with rivastigmine capsules or&nbsp;oral&nbsp;solution and that may occur with the patch:<\/strong><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Too much saliva<\/li><li>Decreased appetite<\/li><li>Restlessness<\/li><li>General malaise<\/li><li>Trembling or feeling of confusion<\/li><li>Increased sweating<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Irregular heartbeat (eg fast heartbeat)<\/li><li>Difficulty sleeping<\/li><li>Stumble unintentionally<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cramps (seizures)<\/li><li>Intestinal ulcers<\/li><li>Chest pain &#8211; can be caused by a heart attack<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High\u00a0blood pressure<\/li><li>Inflammation\u00a0of the pancreas &#8211; signs of it include severe pain in the upper abdomen, usually with nausea and vomiting<\/li><li>Gastrointestinal bleeding &#8211; manifests as blood in the stool or case of vomiting<\/li><li>Seeing things that are not real (hallucinations)<\/li><li>Some people who have had severe vomiting have had stretch marks in the esophagus (esophagus, the tube that connects the mouth to the stomach)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Rigmin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and patch envelope after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not store above 25 \u00b0 C.<\/li><li>Keep the transdermal patch in the patch envelope until use.<\/li><li>Do not use the patch if you see that it is damaged or if the patch envelope shows signs of opening.<\/li><li>After removing the patch, fold it double with the adhesive side inwards and press it together.\u00a0Put the used patch back in the plaster envelope and throw it away so that children cannot get hold of it.\u00a0Do not poke in the eyes with your fingers and wash your hands with soap and water after removing the patch.\u00a0Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines no longer required.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance in Rigmin\u00a0transdermal patch\u00a0is rivastigmine.Rigmin 4.6 mg \/ 24 hours: Each\u00a0patch\u00a0that releases 4.6 mg rivastigmine per 24 hours is 5 cm\u00a0<sup>2<\/sup>\u00a0and contains 9 mg rivastigmine.Rigmin 9.5 mg \/ 24 hours: Each\u00a0patch\u00a0that releases 9.5 mg of rivastigmine per 24 hours is 10 cm\u00a0<sup>2<\/sup>\u00a0and contains 18 mg of rivastigmine.<\/li><li>The other ingredients are lacquered polyethylene terephthalate film, all-rac-\u03b1-Tocopherol, poly (butyl methacrylate, methyl methacrylate), copolymer (3: 1), acrylic copolymer, silicone, dimethicone, polyester film coated with fluoropolymer, resin, pigment, organic polymers\/resins.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Rigmin 4.6 mg \/ 24 hours\u00a0transdermal patch\u00a0is a thin\u00a0matrix-type transdermal patch and consists of three layers.\u00a0The outside of the patch film is beige and marked with \u201cRIV\u201d and \u201c4.6 mg \/ 24 h\u201d.<\/p>\n\n\n\n<p>Rigmin 9.5 mg \/ 24 hours\u00a0transdermal patch\u00a0is a thin\u00a0matrix-type transdermal patch and consists of three layers.\u00a0The outside of the patch film is beige and marked with &#8220;RIV&#8221; and &#8220;9.5 mg \/ 24 h&#8221;.<\/p>\n\n\n\n<p>Each\u00a0transdermal patch\u00a0is sealed in a patch envelope.\u00a0Depot patches\u00a0are available in pack sizes of 7, 30, 60 (2 packs of 30), and 90 (3 packs of 30)\u00a0depot patches.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Novartis Pharma GmbH, Roonstrasse 25, D-90429 Nuremberg, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The active substance in Rigmin transdermal patch is rivastigmine.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22974,19007,22970,22973,3354,3357,22971,19005,22972,19006],"class_list":["post-22103","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-rigmin","tag-benefits-of-rivastigmine","tag-rigmin","tag-rigmin-side-effects","tag-rivastigmine","tag-rivastigmine-side-effects","tag-what-is-rigmin","tag-what-is-rivastigmine","tag-what-rigmin-is-used-for","tag-what-rivastigmine-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22103"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22103\/revisions"}],"predecessor-version":[{"id":22127,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22103\/revisions\/22127"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}