{"id":22022,"date":"2022-06-16T07:25:46","date_gmt":"2022-06-16T07:25:46","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22022"},"modified":"2022-06-16T09:47:15","modified_gmt":"2022-06-16T09:47:15","slug":"revastad","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/revastad\/","title":{"rendered":"Revastad &#8211; Sildenafil uses, dose and side effects"},"content":{"rendered":"\n<p>20 mg&nbsp;film-coated tablets<br>sildenafil<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Revastad is and what it is used for<\/h2>\n\n\n\n<p>Revastad contains the active substance sildenafil which belongs to a group of medicines called&nbsp;phosphodiesterase&nbsp;type 5 (PDE5) inhibitors.<\/p>\n\n\n\n<p>Revastad lowers&nbsp;blood pressure&nbsp;in the lungs by dilating the blood vessels in the lungs.<\/p>\n\n\n\n<p>Sildenafil is used to treat adults and children and adolescents from 1 to 17 years of age with high&nbsp;blood pressure&nbsp;in the blood vessels of the lungs (&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;).<\/p>\n\n\n\n<p>Sildenafil contained in Revastad may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Revastad<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Revastad<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sildenafil or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are taking medicines that contain nitrates or nitric oxide donors such as amyl nitrite.\u00a0These medications are often given to relieve angina (or\u00a0angina pectoris\u00a0).\u00a0Revastad may cause a serious increase in the effect of these drugs.\u00a0Tell your doctor if you are taking any of these medicines.\u00a0If you are not sure, ask your doctor or pharmacist<\/li><li>if you take riociguat.\u00a0This medicine is used to treat\u00a0pulmonary\u00a0arterial\u00a0hypertension\u00a0(ie high\u00a0blood pressure\u00a0in the lungs) and\u00a0chronic\u00a0thromboembolic\u00a0pulmonary\u00a0hypertension\u00a0(ie high\u00a0blood pressure\u00a0in the lungs due to blood clots).\u00a0PDE5 inhibitors, such as sildenafil, have been shown to increase the antihypertensive effect of this medicine.\u00a0If you are taking riociguat or if you are not sure, talk to your doctor<\/li><li>if you have recently had a\u00a0stroke, heart attack, severe liver disease, or very low\u00a0blood pressure\u00a0(&lt;90\/50 mmHg)<\/li><li>if you are taking medicines containing\u00a0ketoconazole\u00a0or itraconazole to treat fungal infections or medicines containing ritonavir (for\u00a0HIV\u00a0)<\/li><li>if you have ever before lost your sight due to a problem with the blood flow to the nerve in the eye called non-arteritic anterior ischemic optic infarction\/neuropathy (NAION).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to a doctor before taking Revastad if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have a disease due to a blocked or narrowed vein in the lung, rather than a blocked or narrowed\u00a0artery<\/li><li>have severe heart problems<\/li><li>have problems with the chambers of the heart<\/li><li>have high\u00a0blood pressure\u00a0in the blood vessels of the lungs<\/li><li>have low\u00a0blood pressure\u00a0at rest<\/li><li>loses a large number of body fluids (\u00a0dehydration\u00a0) which can occur if you sweat a lot or do not drink enough fluid.\u00a0This can happen if you are sick with fever, vomiting, or diarrhea<\/li><li>have a rare inherited eye disease (\u00a0retinitis pigmentosa\u00a0)<\/li><li>have abnormal\u00a0red blood cells\u00a0(sickle cell anemia), blood cell cancer (\u00a0leukemia\u00a0),\u00a0bone marrow\u00a0cancer (multiple\u00a0myeloma\u00a0)<\/li><li>any disease of the penis or deformed penis<\/li><li>right now have\u00a0stomach ulcers\u00a0or a bleeding disorder (such as\u00a0hemophilia\u00a0) or problems with nosebleeds<\/li><li>uses drugs for\u00a0erectile dysfunction.<\/li><\/ul>\n\n\n\n<p>When used to treat male\u00a0erectile dysfunction\u00a0(ED), the following\u00a0side effects\u00a0on vision have been reported with PDE5 inhibitors, including sildenafil, at an unknown frequency: partial, sudden, temporary, or permanent visual impairment or loss of vision in one or both eyes.<\/p>\n\n\n\n<p>If you experience sudden visual impairment or loss of vision,&nbsp;<strong>stop taking Revastad and contact your doctor immediately<\/strong>&nbsp;(see also section 4).<\/p>\n\n\n\n<p>Prolonged and sometimes painful\u00a0erections\u00a0have been reported in men after using sildenafil.\u00a0If you get an\u00a0erection\u00a0that lasts longer than 4 hours,\u00a0<strong>stop taking Revastad and contact your doctor immediately<\/strong>\u00a0(see also section 4).<\/p>\n\n\n\n<p><strong>Especially to take into account patients with kidney or liver problems<\/strong><\/p>\n\n\n\n<p>You should tell your doctor if you have kidney or liver problems, as your&nbsp;dose&nbsp;may need to be adjusted.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Revastad should not be given to children under 1 year of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Revastad<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs containing nitrates, or nitric oxide donors such as amyl nitrite.\u00a0These medicines are often given to relieve\u00a0angina pectoris\u00a0or angina (see section 2. What you need to know before you take Revastad)<\/li><li>tell your doctor or pharmacist if you are already taking riociguat<\/li><li>treatment for\u00a0pulmonary\u00a0hypertension\u00a0(eg\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tracleer\/\">bosentan<\/a>, iloprost)<\/li><li>medicines containing\u00a0St. John&#8217;s wort (herbal medicine), rifampicin (used to treat bacterial infections), carbamazepine,\u00a0phenytoin,\u00a0and phenobarbital (used, among others, to treat\u00a0epilepsy\u00a0)<\/li><li>blood-thinning drugs (eg\u00a0warfarin\u00a0) even if they did not show any side effects<\/li><li>medicines containing erythromycin, clarithromycin, telithromycin (\u00a0antibiotics\u00a0for the treatment of specific bacterial\u00a0infections\u00a0), saquinavir (for the treatment of\u00a0HIV\u00a0), or nefazodone (for depression), as your\u00a0dose\u00a0may need to be adjusted<\/li><li>alpha-receptor blockers (eg\u00a0doxazosin\u00a0) for the treatment of high\u00a0blood pressure\u00a0or prostate problems, as the combination of the two drugs, can cause symptoms that lead to a decrease in your\u00a0blood pressure\u00a0(eg dizziness and dizziness).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Revastad with food, drink, and alcohol<\/h2>\n\n\n\n<p>You should not drink grapefruit juice while you are being treated with Revastad.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Revastad should be used during pregnancy only when needed.<\/p>\n\n\n\n<p>Revastad should not be used in women of&nbsp;childbearing potential&nbsp;unless appropriate contraception is used.<\/p>\n\n\n\n<p>Stop breastfeeding when you start treatment with Revastad.\u00a0Revastad should not be given to breastfeeding women, as it is not known if the medicine passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Revastad may cause dizziness and affect vision.&nbsp;You should be aware of how you react to the medicine before driving or using machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Revastad contains lactose and sodium<\/h2>\n\n\n\n<p><strong>Revastad contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Revastad contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per film-coated tablet, ie essentially &#8216; sodium-free.\u00a0is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Revastad<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p><em><strong>For adults<\/strong>&nbsp;:<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is 20 mg (1 tablet) three times daily.<\/p>\n\n\n\n<p>This medicine should only be used when&nbsp;administering&nbsp;20 mg three times daily.&nbsp;Other forms of medicine are available for the treatment of patients weighing less than 20 kg, as well as for younger patients who are unable to swallow tablets.<\/p>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Leave 6 &#8211; 8 hours between\u00a0doses.\u00a0Can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p><strong>For children and adolescents between 1 and 17 years of age who weigh:<\/strong><\/p>\n\n\n\n<p><strong>MORE than 20 kg<\/strong>: the recommended\u00a0dose\u00a0is 20 mg (1 tablet) three times daily.<\/p>\n\n\n\n<p><strong>LESS THAN 20 kg<\/strong>: the recommended\u00a0dose\u00a0is 10 mg three times daily.<\/p>\n\n\n\n<p>Higher&nbsp;doses&nbsp;should not be used in children.<\/p>\n\n\n\n<p>This medicine should only be used when&nbsp;administering&nbsp;20 mg three times daily.&nbsp;Other forms of medicine are available for the treatment of patients weighing less than 20 kg, as well as for younger patients who are unable to swallow tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Revastad than you should&nbsp;<\/h2>\n\n\n\n<p>Do not take more medicines than your doctor tells you to do.\u00a0If you take more medicines than you have been told to take, contact your doctor immediately.\u00a0Taking more Revastad than you should increase the risk of known\u00a0side effects.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has accidentally ingested the medicine, contact a doctor or hospital immediately for an assessment of the risk and advice. \u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Revastad<\/h2>\n\n\n\n<p>If you forget to take Revastad, take a\u00a0dose\u00a0as soon as you remember.\u00a0Then continue to take your medicine at the usual time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Revastad<\/h2>\n\n\n\n<p>Sudden discontinuation of Revastad treatment may make your symptoms worse.&nbsp;Do not stop taking Revastad unless your doctor tells you to.&nbsp;Your doctor may ask you to reduce your&nbsp;dose&nbsp;for a few days before stopping completely.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Most serious side effects:<\/strong><\/p>\n\n\n\n<p>If you experience any of the following\u00a0side effects,\u00a0<strong>stop taking Revastad and contact your doctor immediately<\/strong>\u00a0(see also section 2):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you experience a sudden deterioration or loss of vision (no known frequency)<\/li><li>if you have an&nbsp;erection&nbsp;that lasts longer than 4 hours.&nbsp;Prolonged and sometimes painful&nbsp;erections&nbsp;have been reported in men after taking sildenafil (no known frequency).<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>flushing<\/li><li>digestive problems<\/li><li>diarrhea<\/li><li>pain in the arms and legs.<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>user):<\/li><li>infection&nbsp;under the skin<\/li><li>flu-like symptoms<\/li><li>sinusitis<\/li><li>decreased number of&nbsp;red blood cells&nbsp;(&nbsp;anemia&nbsp;)<\/li><li>fluid accumulation in the body<\/li><li>difficulty sleeping<\/li><li>anxiety<\/li><li>migraine<\/li><li>shaking<\/li><li>numbness and tingling<\/li><li>burning sensation<\/li><li>impaired skin sensitivity<\/li><li>bleeding at the back of the eye<\/li><li>impact on vision<\/li><li>blurred vision and light shading<\/li><li>effect on color vision<\/li><li>eye irritation<\/li><li>bloodshot eyes \/ red eyes<\/li><li>dizziness<\/li><li>tracheal catarrh<\/li><li>nosebleeds<\/li><li>Runny nose<\/li><li>cough<\/li><li>nasal congestion<\/li><li>gastrointestinal inflammation<\/li><li>heartburn<\/li><li>hemorrhoids<\/li><li>stretched abdomen<\/li><li>dry mouth<\/li><li>hair loss<\/li><li>reddening of the skin<\/li><li>night sweats<\/li><li>muscle aches<\/li><li>back pain and increased body temperature.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased\u00a0visual acuity<\/li><li>double vision<\/li><li>abnormal feeling in the eyes<\/li><li>bleeding in the penis<\/li><li>presence of blood in semen and\/or urine<\/li><li>breast augmentation in men.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><li>sudden decrease or loss of hearing<\/li><li>lowered\u00a0blood pressure.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Additional side effects in children and adolescents<\/h2>\n\n\n\n<p><strong>The following serious&nbsp;side effects&nbsp;have been reported commonly<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pneumonia<\/li><li>heart failure<\/li><li>right ventricular failure<\/li><li>heart-related\u00a0shock<\/li><li>high\u00a0blood pressure\u00a0in the lungs<\/li><li>chest pain<\/li><li>fainting<\/li><li>respiratory tract infection<\/li><li>tracheal inflammation<\/li><li>viral infection of the stomach and intestines<\/li><li>urinary tract infection<\/li><li>caries.<\/li><\/ul>\n\n\n\n<p><strong>The following serious&nbsp;adverse reactions&nbsp;were considered treatment-related and have been reported as uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions (such as skin rash, swelling of the face, lips, and tongue, wheezing, difficulty breathing and swallowing)<\/li><li>cramps<\/li><li>irregular heartbeats<\/li><li>hearing loss<\/li><li>respiratory distress<\/li><li>inflammation\u00a0of the stomach and intestines<\/li><li>wheezing due to obstructed airflow.<\/li><\/ul>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>vomiting<\/li><li>throat infection<\/li><li>fever<\/li><li>diarrhea<\/li><li>influenza<\/li><li>nosebleed.<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>increased&nbsp;erection<\/li><li>pneumonia<\/li><li>Runny nose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Revastad<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is sildenafil.\u00a01 tablet contains 20 mg of sildenafil (as citrate).<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p><em>Tablet core<\/em>:\u00a0lactose monohydrate, microcrystalline cellulose (E460), hydroxypropylcellulose (E463), croscarmellose sodium (E468),\u00a0colloidal\u00a0anhydrous silica (E551), sodium stearyl fumarate (E485).<\/p>\n\n\n\n<p><em>Film coating<\/em>: Opadry II White (consisting of hypromellose 2910 (E464)), titanium dioxide (E171), FCC polydextrose (E1200), talc (E553b), maltodextrin, medium-chain triglycerides.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Revastad is a round, biconvex, white film-coated tablet with a diameter of about 7.1 mm and a thickness of about 3.4 mm.<\/p>\n\n\n\n<p>The tablets are supplied in PVC \/ PVdC \/ Al blisters containing<\/p>\n\n\n\n<p>30, 90, or 100 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Alternative manufacturers<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Revastad contains the active substance sildenafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22828,22832,22831,9336,13284,9338,22829,9337,22830,13282],"class_list":["post-22022","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-revastad","tag-revastad-side-effects","tag-revastad-tablet","tag-sildenafil","tag-sildenafil-side-effects","tag-sildenafil-tablet","tag-what-is-revastad","tag-what-is-sildenafil","tag-what-revastad-is-used-for","tag-what-sildenafil-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22022","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22022"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22022\/revisions"}],"predecessor-version":[{"id":22048,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22022\/revisions\/22048"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22022"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}