{"id":22006,"date":"2022-06-16T07:07:59","date_gmt":"2022-06-16T07:07:59","guid":{"rendered":"https:\/\/zeepedia.com\/?p=22006"},"modified":"2022-06-16T09:48:11","modified_gmt":"2022-06-16T09:48:11","slug":"resonium","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/resonium\/","title":{"rendered":"Resonium &#8211; Sodium polystyrene sulfonate uses, dose and side effects"},"content":{"rendered":"\n<p>powder for oral\/rectal\u00a0suspension<br>sodium polystyrene sulfonate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Resonium is and what it is used for<\/h2>\n\n\n\n<p>Resonium is a so-called ion exchanger, which during the passage in the gastrointestinal tract binds\u00a0potassium\u00a0in exchange for\u00a0sodium.\u00a0The powder is not absorbed into the body but only passes through the gastrointestinal tract.<\/p>\n\n\n\n<p>Resonium is used to lower elevated levels of&nbsp;potassium&nbsp;in the blood.&nbsp;Excessive levels of&nbsp;potassium&nbsp;can lead to heart failure.<\/p>\n\n\n\n<p>The use of Resonium requires regular blood tests, as it is important that potassium levels are not reduced too quickly and that the balance of other salts such as&nbsp;calcium&nbsp;and&nbsp;magnesium&nbsp;is not disturbed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Resonium<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Resonium<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sodium polystyrene sulphonate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if the amount of&nbsp;potassium&nbsp;in your blood is less than 5 mmol \/ l.<\/li><li>in certain intestinal diseases.<\/li><\/ul>\n\n\n\n<p>Resonium should not be given orally to newborns and not at all to newborns with impaired bowel function.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Take special care with Resonium:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have high&nbsp;blood pressure<\/li><li>if you have&nbsp;heart failure<\/li><li>if you have fluid retention with swelling<\/li><li>if you become constipated during treatment<\/li><\/ul>\n\n\n\n<p>Concomitant use with sorbitol is not recommended as there is a risk of serious gastrointestinal side effects that may damage the intestinal tissue.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Resonium<\/h2>\n\n\n\n<p>Resonium can affect the effect of medicines taken by mouth and should therefore be taken either at least 3 hours before or 3 hours after other medication.&nbsp;If you have delayed gastric emptying (so-called gastroparesis), there should be 6 hours between the use of Resonium and other medicines.<\/p>\n\n\n\n<p>Concomitant use with sorbitol is not recommended due to the risk of serious gastrointestinal side effects that may cause tissue damage to the intestine.\u00a0Deaths due to gastrointestinal side effects when used concomitantly have been reported.\u00a0The reports refer to cases where sorbitol has been used as a\u00a0laxative.\u00a0There is no information on sorbitol used as an additive (sweetener) in medicines and foods.<\/p>\n\n\n\n<p>The effect of Resonium can be affected by certain medicines for acid stomach (antacids) and certain medicines for constipation (\u00a0laxatives\u00a0).\u00a0The use of Resonium may affect the effect of medicines containing\u00a0digoxin.<\/p>\n\n\n\n<p>Combination with thyroid hormones or lithium may require dose adjustment.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Resonium is not absorbed from the gastrointestinal tract, but there is no data on its use during pregnancy and lactation.<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No known effect on the ability to drive or perform precision work.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Resonium contains sodium:<\/h2>\n\n\n\n<p>This medicine contains 1.7 g of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per\u00a0dose.\u00a0This corresponds to 85% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you need to take Resonium daily for an extended period, especially if you have been prescribed a low-salt diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Resonium<\/h2>\n\n\n\n<p>Dose&nbsp;one should be determined by a doctor, who will adjust it individually for you with careful control of the salt balance.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Resonium should be ingested to avoid the risk of inhalation.<\/p>\n\n\n\n<p><em>The usual\u00a0dose\u00a0for adults:<\/em>\u00a01 ironed dose (approx. 15 g) 3-4 times daily.<\/p>\n\n\n\n<p>The preparation is taken stirred in a little water or porridge, juice, or jam.\u00a0Can also be taken as an enema, which must then be retained for the time specified by the doctor.<\/p>\n\n\n\n<p>Dosage measurements are included in the package.&nbsp;A coated dosage measure holds about 15 g.<\/p>\n\n\n\n<p>Resonium should not be taken at the same time as other oral medicines.&nbsp;See section \u201cOther medicines and Resonium\u201d for more information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Resonium than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>Overdose can cause symptoms of salt balance disorders, such as irritability, confusion, delayed thinking, muscle weakness, weakened reflexes, and in some cases paralysis symptoms.\u00a0Respiratory arrest is a possible serious consequence of this development.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Resonium<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Provided that the salt balance in the body is not disturbed, the\u00a0side effect\u00a0consists almost exclusively of difficulty in swallowing the fairly large amount of stirred powder, or in achieving sufficient variation in food\/drink for mixing the powder, so that in the long run it does not become nauseating.<br><br>Serious gastrointestinal side effects such as tissue damage to the intestine (in some cases fatal) have been reported.\u00a0Talk to your doctor or nurse immediately if you notice any of the following serious\u00a0side\u00a0effects<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe abdominal pain, pain in the rectum<\/li><li>Flatulence, severe constipation<\/li><li>Severe nausea and vomiting<\/li><li>Black, bloody, or tarry stools, coughing up blood or having vomiting similar to coffee grounds.<\/li><\/ul>\n\n\n\n<p><em>Common\u00a0side effects\u00a0(more than 1 person in 100 affected):<br><\/em>Constipation or lump in the stools, nausea, nausea, vomiting, loss of appetite, and diarrhea.\u00a0Disturbances in the salt balance.<br><br>Rare\u00a0side effects\u00a0(\u00a0\u00a0less than 1 in 1000 people affected):<br>Tracheal catarrh,\u00a0pneumonia\u00a0(often due to inhalation of the powder).\u00a0Constipation in the intestine, lack of oxygen in the intestine,\u00a0inflammation\u00a0in the large intestine.\u00a0Sores or severe tissue damage to the intestine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Resonium<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>If Resonium is stirred into water, this&nbsp;preparation&nbsp;should be used within 24 hours.&nbsp;Heating should be avoided.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is sodium polystyrene sulfonate.&nbsp;100 g of powder contains 99.934 g of sodium polystyrene sulfonate.<\/li><li>The other ingredients are vanillin and saccharin.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Light brown powder.<\/p>\n\n\n\n<p>Pack size: Plastic jar containing 450 g powder for oral\/rectal\u00a0suspension, and dosage measure that holds about 15 g.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Sanofi AB, Box 30052, 104 25 Stockholm<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Sanofi-Synthelabo Ltd., Newcastle-upon-Tyne, United Kingdom<\/p>\n\n\n\n<p>and<\/p>\n\n\n\n<p>Sanofi Winthrop Industry, Amilly, France<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Resonium is a so-called ion exchanger, which during the passage in the gastrointestinal tract binds potassium in exchange for sodium . The powder is not absorbed into the body but only passes through the gastrointestinal tract.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22903,22898,22899,22902,22894,22897,22900,22895,22901,22896],"class_list":["post-22006","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-resonium","tag-benefits-of-sodium-polystyrene-sulfonate","tag-resonium","tag-resonium-side-effects","tag-sodium-polystyrene-sulfonate","tag-sodium-polystyrene-sulfonate-side-effects","tag-what-is-resonium","tag-what-is-sodium-polystyrene-sulfonate","tag-what-resonium-is-used-for","tag-what-sodium-polystyrene-sulfonate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=22006"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22006\/revisions"}],"predecessor-version":[{"id":22056,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/22006\/revisions\/22056"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=22006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=22006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=22006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}