{"id":21926,"date":"2022-06-14T07:53:18","date_gmt":"2022-06-14T07:53:18","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21926"},"modified":"2022-06-14T13:20:55","modified_gmt":"2022-06-14T13:20:55","slug":"repaglinide-krka","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/repaglinide-krka\/","title":{"rendered":"Repaglinide Krka &#8211; Repaglinide uses, dose and side effects"},"content":{"rendered":"\n<p>0.5 mg, 1 mg, 2 mg&nbsp;repaglinide&nbsp;tablets<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Repaglinide Krka is and what it is used for<\/h2>\n\n\n\n<p>Repaglinide Krka contains repaglinide and is an oral tablet for the treatment of\u00a0diabetes.\u00a0Repaglinide Krka helps your\u00a0pancreas\u00a0to produce more\u00a0insulin\u00a0and lower your blood sugar (\u00a0glucose\u00a0).<\/p>\n\n\n\n<p>Type 2&nbsp;diabetes&nbsp;is a disease in which the pancreas does not produce enough&nbsp;insulin&nbsp;to control the level of sugar in your blood or where your body does not respond normally to the&nbsp;insulin&nbsp;it produces.<\/p>\n\n\n\n<p>Repaglinide Krka is used to control type 2&nbsp;diabetes&nbsp;in adults as a supplement to diet and exercise.&nbsp;Treatment is usually started if diet, exercise and weight loss alone are not enough to control (or lower) your blood sugar.<\/p>\n\n\n\n<p>Repaglinide Krka can also be given with\u00a0metformin, another diabetes medicine.<\/p>\n\n\n\n<p>Repaglinide Krka lowers blood sugar, which helps prevent complications of your\u00a0diabetes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Repaglinide Krka<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Repaglinide Krka<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to repaglinide or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have type 1\u00a0diabetes.<\/li><li>if the acid level in your blood is elevated (diabetic ketoacidosis).<\/li><li>if you have severe liver disease.<\/li><li>if you have gemfibrozil (a medicine used to reduce blood fats).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Repaglinide Krka:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have liver problems.\u00a0Repaglinide Krka is not recommended for patients with moderate liver disease.\u00a0Repaglinide Krka should not be taken if you have severe liver disease (see Do not take Repaglinide Krka).<\/li><li>if you have kidney problems.\u00a0Repaglinide Krka should be used with caution.<\/li><li>if you are going to have major surgery or have recently had a serious illness or\u00a0infection.\u00a0In such cases, diabetes control may be insufficient.<\/li><li>if you are under 18 or over 75 years of age.\u00a0Repaglinide Krka can then not be recommended, as studies in these age groups are lacking.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor if any of the above apply to you.&nbsp;Then you may not be treated with Repaglinide Krka, but your doctor will advise you.<\/p>\n\n\n\n<p><strong>Children and young people<\/strong><\/p>\n\n\n\n<p>Do not take this medicine if you are under 18 years of age.<\/p>\n\n\n\n<p><strong>If you get an insulin sensation (low blood sugar)<\/strong><\/p>\n\n\n\n<p>You get insulin sensation (&nbsp;hypoglycaemia&nbsp;) if your blood sugar gets too low.&nbsp;It could happen:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you take more Repaglinide Krka than you should<\/li><li>if you exercise more than usual<\/li><li>if you are taking other medicines or have kidney or liver problems (see other sections under 2. What you need to know before taking Repaglinide Krka).<\/li><\/ul>\n\n\n\n<p><strong>The warning signs of low blood sugar<\/strong>&nbsp;can come on suddenly and manifest themselves as: cold sweat;&nbsp;cold and pale skin;&nbsp;headache;&nbsp;palpitation;&nbsp;nausea;&nbsp;strong hunger;&nbsp;temporary vision changes;&nbsp;drowsiness;&nbsp;unusual fatigue and weakness;&nbsp;nervousness or tremors;&nbsp;feelings of anxiety;&nbsp;confusion;&nbsp;concentration difficulties.<\/p>\n\n\n\n<p><strong>If your blood sugar is low or you get an insulin sensation:<\/strong>\u00a0eat glucose tablets or a snack or a drink that contains a lot of sugar and then rest.<\/p>\n\n\n\n<p><strong>When the symptoms of\u00a0hypoglycaemia\u00a0have disappeared or your blood sugar level has stabilized<\/strong>, you can continue treatment with Repaglinide Krka.<\/p>\n\n\n\n<p><strong>Tell people around you that you have\u00a0diabetes\u00a0and that if you become unconscious<\/strong>, they should put you on the sidelines and get medical attention immediately.\u00a0They must not give you anything to eat or drink.\u00a0Then there is a risk that you will suffocate.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If severe insulin sensitivity<\/strong>&nbsp;is not treated, it can cause brain damage (temporary or permanent) and even death.<\/li><li><strong>If you get an insulin sensation<\/strong>&nbsp;and lose consciousness, or if you get a lot of insulin sensations, talk to your doctor.&nbsp;Dose&nbsp;a Repaglinide Krka, diet or exercise may need to be adjusted.<\/li><\/ul>\n\n\n\n<p><strong>If your blood sugar gets too high<\/strong><\/p>\n\n\n\n<p>Your blood sugar may become too high (this is called&nbsp;hyperglycaemia&nbsp;).&nbsp;It can have the following causes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you take too little&nbsp;Repaglinide&nbsp;Krka<\/li><li>whether you have an&nbsp;infection&nbsp;or fever<\/li><li>if you have eaten more than usual<\/li><li>if you have exercised less than usual.<\/li><\/ul>\n\n\n\n<p>The warning signs of high blood sugar gradually appear.\u00a0They manifest as: increased urine output;\u00a0thirst;\u00a0dry skin and\u00a0dry mouth.\u00a0Talk to your doctor.\u00a0Dose\u00a0a Repaglinide Krka, diet or exercise may need to be adjusted.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Repaglinide Krka<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>You can take Repaglinide Krka with\u00a0metformin, another diabetes medicine if your doctor tells you to.<\/p>\n\n\n\n<p>If you are taking gemfibrozil (used to treat high blood fats), do not take Repaglinide Krka.<\/p>\n\n\n\n<p>Your body may react differently to Repaglinide Krka if you are taking other medicines, especially these:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>MAO inhibitors\u00a0(used to treat depression).<\/li><li>Beta-receptor blockers (used to treat high\u00a0blood pressure\u00a0or heart disease).<\/li><li>ACE inhibitors\u00a0(angiotensin converters) (are used to treat certain heart conditions).<\/li><li>Salicylates (included in some painkillers).<\/li><li>Octreotide (used to treat cancer).<\/li><li>Non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0) (painkillers).<\/li><li>Steroids\u00a0(anabolic\u00a0steroids\u00a0and\u00a0corticosteroids\u00a0&#8211; used in\u00a0anaemia\u00a0or treatment of\u00a0inflammation\u00a0).<\/li><li>Oral contraceptives (\u00a0birth control pills\u00a0).<\/li><li>Thiazides\u00a0(\u00a0diuretics\u00a0or diuretics).<\/li><li>Danazol (used to treat breast cysts and endometrial tissue outside the uterus, called\u00a0endometriosis\u00a0).<\/li><li>Thyroid drugs (used to treat low levels of thyroid hormones).<\/li><li>Adrenergic agents (used to treat\u00a0asthma\u00a0).<\/li><li>Clarithromycin, trimethoprim, and rifampicin (\u00a0antibiotics\u00a0).<\/li><li>Itraconazole,\u00a0ketoconazole\u00a0(antifungal).<\/li><li>Gemfibrozil (used to treat high blood fats).<\/li><li>Ciclosporin (used to\u00a0inhibit\u00a0the immune system).<\/li><li>Deferasirox (used to remove excess iron from the body).<\/li><li>Clopidogrel (prevents the formation of blood clots).<\/li><li>Phenytoin, carbamazepine, phenobarbital (used to treat\u00a0epilepsy\u00a0).<\/li><li>St. John&#8217;s wort\u00a0(herbal medicine).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Repaglinide Krka with food, drink and alcohol<\/h2>\n\n\n\n<p>Alcohol may alter Repaglinide Krka&#8217;s ability to lower blood sugar.&nbsp;Pay attention to signs of insulin sensation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<p>You should not take Repaglinide Krka if you are pregnant or planning to become pregnant.<\/p>\n\n\n\n<p>You should not take Repaglinide Krka if you are breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Your ability to drive or use machines may be affected if your blood sugar is too high or too low.&nbsp;Remember that you can&nbsp;put&nbsp;yourself and others at risk.&nbsp;Talk to your doctor if you can drive if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have insulin sensations<\/li><li>receive few or no warning signs of low blood sugar<\/li><\/ul>\n\n\n\n<p><strong>Repaglinide Krka contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Repaglinide Krka<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Consult a doctor if you are unsure.<\/p>\n\n\n\n<p>Your doctor will determine your\u00a0dose.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The usual starting dose is 0.5 mg before each main meal.&nbsp;Swallow the tablets with a glass of water immediately before or up to 30 minutes before each main meal.<\/li><li>Your doctor may increase the&nbsp;dose&nbsp;to one up to 4 mg immediately before or up to 30 minutes before each main meal.&nbsp;The maximum recommended daily&nbsp;dose&nbsp;is 16 mg.<\/li><\/ul>\n\n\n\n<p>Do not take more Repaglinide Krka than your doctor has prescribed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Repaglinide Krka than you should&nbsp;<\/h2>\n\n\n\n<p>If you take too many tablets, your blood sugar may become too low and lead to insulin sensation.&nbsp;See If you get an insulin sensation (low blood sugar) for more information on what this is and how it is treated.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Repaglinide Krka<\/h2>\n\n\n\n<p>If you miss a\u00a0dose, take the next\u00a0dose\u00a0as usual.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Repaglinide Krka<\/h2>\n\n\n\n<p>Keep in mind that you will not get the desired effect if you stop taking Repaglinide Krka.\u00a0Your\u00a0diabetes\u00a0may worsen.\u00a0If any change is needed, you must contact your doctor.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Low blood sugar (&nbsp;hypoglycaemia&nbsp;)<\/strong><\/p>\n\n\n\n<p>The most common\u00a0side effect\u00a0is low blood sugar, which may affect up to 1 in 10 people (see &#8221;\u00a0<em>If you get a feeling of insulin (low blood sugar)<\/em>\u00a0&#8221; in section 2).\u00a0Reactions to low blood sugar are generally mild\/moderate but can sometimes develop into hypoglycaemic unconsciousness or\u00a0coma.\u00a0If this happens, seek medical attention immediately.<\/p>\n\n\n\n<p><strong>Allergy<\/strong><\/p>\n\n\n\n<p>Allergies\u00a0are very rare (may affect up to 1 in 10,000 people).\u00a0Symptoms such as swelling, difficulty breathing, palpitations, dizziness and sweating may be signs of\u00a0an anaphylactic reaction.\u00a0Contact a doctor immediately.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1&nbsp;<\/em><em>in 10&nbsp;<\/em><em>people&nbsp;<\/em><em>)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abdominal pain<\/li><li>Diarrhoea<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1&nbsp;<\/em><em>in 1,000&nbsp;<\/em><em>people&nbsp;<\/em><em>)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute coronary heart disease (does not need to be related to the drug).<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting<\/li><li>Constipation<\/li><li>Visual disturbances<\/li><li>Severe liver problems, and abnormal liver function such as an increase in liver enzymes in your blood.<\/li><\/ul>\n\n\n\n<p>No known frequency (can not be calculated from the available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity (such as rash, itchy skin, reddening of the skin, swelling of the skin; if these symptoms occur, contact your doctor as soon as possible)<\/li><li>Nausea.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Repaglinide Krka<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original package.<\/p>\n\n\n\n<p>Sensitive to light.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is repaglinide.\u00a0Each tablet contains 0.5 mg, 1 mg, 2 mg repaglinide.<\/li><li>The other ingredients are microcrystalline cellulose (E460), calcium hydrogen phosphate, croscarmellose sodium, povidone K25,\u00a0glycerol, magnesium stearate, and meglumine, poloxamer, yellow iron oxide (E172) only in 1 mg tablets and red iron oxide (E172) only in 2 mg tablets. See section 2 &#8220;Repaglinide Krka contains sodium&#8221;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The 0.5 mg tablets are white, round and biconvex with bevelled edges.<\/p>\n\n\n\n<p>The 1 mg tablets are light brownish yellow, round and biconvex with bevelled edges with possibly darker dots.<\/p>\n\n\n\n<p>The 2 mg tablets are pink, marbled, round and biconvex with bevelled edges with possibly darker dots.<\/p>\n\n\n\n<p>Packs of 30, 60, 90, 120, 270 or 360 tablets in blisters are available.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p>TAD Pharma GmbH, Heinz-Lohmann-Stra\u00dfe 5, 27472 Cuxhaven, Germany<\/p>\n\n\n\n<p>KRKA &#8211; FARMA doo, DPC Jastrebarsko, Cvetkovi\u0107 bb, 10450 Jastrebarsko, Croatia<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Repaglinide Krka contains repaglinide and is an oral tablet for the treatment of diabetes . Repaglinide Krka helps your pancreas to produce more insulin and lower your blood sugar ( glucose ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[19225,22690,22694,22693,19229,19228,19226,22691,19227,22692],"class_list":["post-21926","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-repaglinide","tag-repaglinide-krka","tag-repaglinide-krka-side-effects","tag-repaglinide-krka-tablet","tag-repaglinide-side-effects","tag-repaglinide-tablet","tag-what-is-repaglinide","tag-what-is-repaglinide-krka","tag-what-repaglinide-is-used-for","tag-what-repaglinide-krka-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21926"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21926\/revisions"}],"predecessor-version":[{"id":21944,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21926\/revisions\/21944"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}