0.5 mg, 1 mg, 2 mg tablets
Repaglinide<\/p>\n\n\n\n
Repaglinide Accord\u00a0contains repaglinide<\/em>\u00a0and is an\u00a0oral tablet for the treatment of\u00a0diabetes<\/em>.\u00a0Repaglinide Accord helps your\u00a0pancreas\u00a0to produce more\u00a0insulin\u00a0and lower your blood sugar (blood glucose).<\/p>\n\n\n\n Repaglinide Accord is used to control type 2\u00a0diabetes\u00a0in adults as a supplement to diet and exercise.\u00a0Treatment is usually started if diet, exercise, and weight loss alone are not enough to control (or lower) your blood sugar.\u00a0Repaglinide Accord can also be given with\u00a0metformin, another diabetes medicine.<\/p>\n\n\n\n Talk to your doctor before taking Repaglinide Accord:<\/p>\n\n\n\n Talk to your doctor<\/strong> if any of the above apply to you. You may not be treated with Repaglinide Accord, but your doctor will advise you.<\/p>\n\n\n\n Do not take this medicine if you are under 18 years of age.<\/p>\n\n\n\n If you get an insulin sensation (low blood sugar)<\/strong><\/p>\n\n\n\n If your blood sugar is low or you get an <\/strong>insulin sensation: eat glucose tablets or a snack or a drink that contains a lot of sugar and then rest.<\/p>\n\n\n\n When the symptoms of\u00a0hypoglycemia<\/strong>\u00a0have disappeared or your blood sugar level has stabilized, you can continue treatment with Repaglinide Accord.<\/p>\n\n\n\n If your blood sugar gets too high<\/strong> \u2022 You have eaten more than usual Tell your doctor<\/strong>\u00a0or pharmacist if you are taking, have recently taken, or might take any other medicines. \u2022 Your body may react differently to Repaglinide Accord if you are taking other medicines, especially these: Alcohol may alter the ability of Repaglinide Accord to lower blood sugar. Pay attention to signs of insulin sensation.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n You should not take Repaglinide Accord if you are pregnant or planning to become pregnant. Your ability to drive or use machines may be affected if your blood sugar is too high or too low. Remember that you can put yourself and others at risk. Talk to your doctor if you can drive a car if you: Always take this medicine exactly as your doctor has told you.\u00a0Consult a doctor if you are unsure. Do not take more Repaglinide Accord than your doctor has prescribed.<\/p>\n\n\n\n If you take too many tablets, your blood sugar may become too low and lead to insulin sensation. See If you get an insulin sensation<\/em> for more information on what this is and how it is treated.<\/p>\n\n\n\n If you miss a\u00a0dose, take the next\u00a0dose\u00a0as usual – do not take a double\u00a0dose.<\/p>\n\n\n\n Keep in mind that you will not get the desired effect if you stop taking Repaglinide Accord. Your diabetes may worsen. If your treatment needs to be changed, always consult your doctor first.<\/p>\n\n\n\n If you have any further questions on the use of Repaglinide Accord, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Low blood sugar (hypoglycemia<\/em><\/strong>) Allergy<\/em><\/strong> Other side effects Common<\/em><\/strong> Rare<\/strong> (may affect up to 1 in 1,000 people) Very rare<\/strong> (may affect up to 1 in 10,000 people) Unknown frequency<\/strong> Reporting of\u00a0side effects\u00a0If<\/strong> Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton, bottle label, and blister after \u201cEXP\u201d.\u00a0The expiration date is the last day of a specified month.\u00a0This is stated on the outer carton and blister foil.<\/p>\n\n\n\n No special storage instructions apply to the medicine.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is repaglinide. The other ingredients are microcrystalline cellulose, anhydrous calcium hydrogen phosphate, maize starch, meglumine, poloxamer 188, povidone, glycerin, magnesium stearate, yellow iron oxide (E172) only in 1 mg tablets, and red iron oxide (E172) only in 2 mg tablets.<\/p>\n\n\n\n The Repaglinide Accord 0.5 mg tablet is white to off-white, round, biconvex, with a beveled edge and marked with \u201cR\u201d on one side and unmarked on the other side.<\/p>\n\n\n\n The tablet Repaglinide Accord 1 mg is light yellow to yellow, round, biconvex, with a beveled edge and marked with \u201cR\u201d on one side and unmarked on the other side, and maybe marbled.<\/p>\n\n\n\n The tablet Repaglinide Accord 2 mg is peach-colored, round, biconvex, with a beveled edge and marked with \u201cR\u201d on one side and unmarked on the other side, maybe marbled.<\/p>\n\n\n\n The tablets are available in the following pack sizes: HDPE bottle with 100 tablets.<\/p>\n\n\n\n Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n Accord Healthcare SLU<\/p>\n\n\n\n World Trade Center, Moll de Barcelona, \u200b\u200bs \/ n,<\/p>\n\n\n\n Edifici Est 6\u00aa planta,<\/p>\n\n\n\n 08039 Barcelona,<\/p>\n\n\n\n Spain<\/p>\n\n\n\n Manufacturer<\/strong><\/p>\n\n\n\n Accord Healthcare Polska Sp.z oo,<\/p>\n\n\n\n ul. Lutomierska 50,95-200 Pabianice, Poland<\/p>\n\n\n\n Accord Healthcare BV,<\/p>\n\n\n\n Winthontlaan 200,<\/p>\n\n\n\n 3526 VK Utrecht,<\/p>\n\n\n\n Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":" Type 2 diabetes is a disease in which the pancreas does not produce enough insulin to control the level of sugar in your blood or where your body does not respond normally to the insulin it produces.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[19225,22695,22699,22698,19229,19228,19226,22696,22697,19227],"class_list":["post-21924","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-repaglinide","tag-repaglinide-accord","tag-repaglinide-accord-side-effects","tag-repaglinide-accord-tablet","tag-repaglinide-side-effects","tag-repaglinide-tablet","tag-what-is-repaglinide","tag-what-is-repaglinide-accord","tag-what-repaglinide-accord-is-used-for","tag-what-repaglinide-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21924","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21924"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21924\/revisions"}],"predecessor-version":[{"id":21945,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21924\/revisions\/21945"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21924"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21924"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21924"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Type 2 diabetes<\/strong> is a disease in which the pancreas does not produce enough insulin to control the level of sugar in your blood or where your body does not respond normally to the insulin it produces.<\/p>\n\n\n\n
Repaglinide Accord lowers blood sugar, which helps prevent complications of your\u00a0diabetes.<\/p>\n\n\n\nWhat you need to know before using Repaglinide Accord<\/h2>\n\n\n\n
Do not take Repaglinide Accord:<\/h2>\n\n\n\n
If you are allergic to repaglinide or any of the other ingredients of this medicine (listed in section 6).
\u2022 if you have type 1 diabetes<\/strong>
\u2022 if the acid level in your blood is<\/strong> elevated ( diabetic ketoacidosis<\/strong> )
\u2022 if you have a severe liver disease<\/strong>
\u2022 if you are taking gemfibrozil<\/strong> (for the treatment of high blood fats).<\/p>\n\n\n\nWarnings and cautions<\/h2>\n\n\n\n
\u2022 if you have\u00a0liver problems.\u00a0<\/strong>Repaglinide Accord is not recommended for patients with moderate liver disease.\u00a0Repaglinide Accord should not be taken if you have severe liver disease (see\u00a0Do not take Repaglinide Accord<\/em>\u00a0).
\u2022 if you have\u00a0kidney problems<\/strong>.\u00a0Repaglinide Accord should then be used with caution.
\u2022 if you are having\u00a0major surgery\u00a0or have recently had a\u00a0serious illness\u00a0or\u00a0infection.\u00a0In such cases, diabetes control may be insufficient.\u00a0\u2022 if you are\u00a0under 18<\/strong>\u00a0or\u00a0over 75 years of age<\/strong>
.\u00a0Repaglinide Accord can then not be recommended, as studies in these age groups are lacking.<\/p>\n\n\n\nChildren and young people<\/h2>\n\n\n\n
You get insulin sensation (hypoglycemia) if your blood sugar gets too low.\u00a0This may happen:
\u2022 if you take too much Repaglinide Accord
\u2022 if you exercise more than usual
\u2022 if you are taking other medicines or have kidney or liver problems (see other sections under 2.\u00a0What you need to know before taking Repaglinide Accord<\/em>\u00a0).<\/p>\n\n\n\n
The warning signs of low blood sugar<\/strong> can come on suddenly and manifest themselves as: cold sweat; cold and pale skin; headache; palpitation; nausea; strong hunger; temporary vision changes; drowsiness; unusual fatigue and weakness; nervousness or tremors; feelings of anxiety; confusion; concentration difficulties.<\/p>\n\n\n\n
Tell people around you that you have\u00a0diabetes\u00a0and that if you become unconscious<\/strong>, they should put you on the sidelines and get medical attention immediately.\u00a0They must not give you anything to eat or drink.\u00a0Then there is a risk that you will suffocate.
\u2022 If untreated insulin sensitivity<\/strong>\u00a0is not treated, it can cause brain damage (temporary or permanent) and even death.
If you get an insulin sensation<\/strong>\u00a0and lose consciousness, or if you get a lot of insulin sensations, talk to your doctor.\u00a0Dose\u00a0a Repaglinide Accord, diet or exercise may need to be adjusted.<\/p>\n\n\n\n
Your blood sugar may get too high (this is called hyperglycemia ). It can have the following causes:
\u2022 You have taken too little Repaglinide Accord
\u2022 You have an infection or fever<\/p>\n\n\n\n
\u2022 You have exercised less than usual.
The warning signs of high blood sugar<\/strong>\u00a0gradually appear.\u00a0They manifest as: increased urine output;\u00a0thirst;\u00a0dry skin and\u00a0dry mouth.\u00a0Talk to your doctor.\u00a0Dose\u00a0a Repaglinide Accord, diet or exercise may need to be adjusted.<\/p>\n\n\n\nOther medicines and Repaglinide Accord<\/h2>\n\n\n\n
You can take Repaglinide Accord together with\u00a0metformin, another diabetes medicine if your doctor tells you to.\u00a0If you are taking gemfibrozil (for the treatment of high blood fats), do not take Repaglinide Accord.<\/p>\n\n\n\n
\u2022\u00a0MAO inhibitors\u00a0(used to treat depression)
\u2022 Beta-receptor blockers (used to treat high\u00a0blood pressure\u00a0or heart disease)
\u2022\u00a0ACE inhibitors\u00a0(used to treat heart disease)
\u2022 Salicylates (included in some painkillers)
\u2022 Octreotide (used to treat cancer)
\u2022 Non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0) (painkillers)
\u2022\u00a0Steroids\u00a0(anabolic )steroids\u00a0and\u00a0corticosteroids\u00a0– used in\u00a0anemia\u00a0or treatment of\u00a0inflammation\u00a0)
\u2022 Oral contraceptives (\u00a0birth control pills\u00a0)
\u2022\u00a0Thiazides\u00a0(\u00a0diuretics\u00a0or diuretics)
\u2022 Danazol (used to treat breast cysts and endometrial tissue outside the uterus, so-called\u00a0endometriosis\u00a0)
\u2022 Thyroid drugs ( used to treat low levels of thyroid hormones)
\u2022 Adrenergic agents (used to treat\u00a0asthma\u00a0)
\u2022 Clarithromycin, trimethoprim, rifampicin (\u00a0antibiotics\u00a0)
\u2022 Itraconazole,\u00a0ketoconazole\u00a0(antifungal)
\u2022 Gemfibrozil (used to treat high blood fats)
\u2022 Ciclosporin (used to\u00a0suppress\u00a0the immune system)
\u2022 Deferasirox (used to remove excess iron from the body )
\u2022 Clopidogrel (prevents blood clots)
\u2022\u00a0Phenytoin, carbamazepine, phenobarbital (used to treat\u00a0epilepsy\u00a0)
\u2022\u00a0St. John’s wort (herbal medicine).<\/p>\n\n\n\nRepaglinide Accord with food, drink, and alcohol<\/h2>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
You should not take Repaglinide Accord if you are breastfeeding.<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
\u2022 often have insulin sensations
\u2022 have few or no warning signs of low blood sugar.<\/p>\n\n\n\nHow to use Repaglinide Accord<\/h2>\n\n\n\n
Your doctor will determine your\u00a0dose.
\u2022 The usual starting dose<\/strong>\u00a0is 0.5 mg before each main meal.\u00a0Swallow the tablets with a glass of water
immediately before or up to 30 minutes before each main meal.
\u2022 Your doctor may increase the\u00a0dose\u00a0by up to 4 mg immediately before or up to 30 minutes before each main meal.\u00a0The maximum recommended daily\u00a0dose\u00a0is 16 mg.<\/p>\n\n\n\nIf you use more Repaglinide Accord than you should <\/h2>\n\n\n\n
If you forget to use Repaglinide Accord<\/h2>\n\n\n\n
If you stop using Repaglinide Accord<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
The most common\u00a0side effect\u00a0is low blood sugar, which may affect up to 1 in 10 people (see\u00a0If you get an insulin sensation\u00a0in section 2).\u00a0Reactions to low blood sugar are generally mild\/moderate but may temporarily develop into hypoglycaemic unconsciousness or\u00a0coma.\u00a0If this happens, seek medical attention immediately.<\/p>\n\n\n\n
Allergies very rare (may affect up to 1 in 10,000 patients).\u00a0Symptoms such as swelling, difficulty breathing, palpitations, dizziness, and sweating may be signs of anaphylactic reaction.\u00a0Contact a doctor immediately.<\/p>\n\n\n\n
(<\/strong> may affect up to 1 in 10 people)
\u2022 Abdominal pain
\u2022 Diarrhea.<\/p>\n\n\n\n
\u2022 Acute coronary heart disease (need not be associated with the medicine).<\/p>\n\n\n\n
\u2022 Vomiting
\u2022 Constipation
\u2022 Visual disturbances
\u2022 Severe liver problems, abnormal liver function, increase in liver enzymes in your blood.<\/p>\n\n\n\n
\u2022 Hypersensitivity (such as rash, itchy skin, reddening of the skin, swelling of the skin)
\u2022 Nausea.<\/p>\n\n\n\n
If you get\u00a0any side effects, talk to your doctor, pharmacist, or nurse.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly via the national reporting system listed in Appendix V. By reporting\u00a0side effects, you can help increase information on the safety of medicines.<\/p>\n\n\n\nHow to store Repaglinide Accord<\/h2>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Repaglinide Accord 0.5 mg: Each tablet contains 0.5 mg repaglinide
Repaglinide Accord 1 mg: Each tablet contains 1 mg repaglinide
Repaglinide Accord 2 mg: Each tablet contains 2 mg repaglinide<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Blister of 30, 90, 120, 180, or 270 tablets.<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n