Important to consider for patients receiving peritoneal dialysis:<\/em><\/p>\n\n\n\nYou may develop\u00a0peritonitis\u00a0(peritonitis) associated with\u00a0peritoneal dialysis.\u00a0This risk can be reduced if you carefully follow the sterile methods during bag changes.\u00a0You should tell your doctor immediately if you get new signs or symptoms of abdominal discomfort, abdominal swelling, abdominal pain, abdominal pain or hard\/stiff abdomen, constipation, fever, chills, nausea, or vomiting.<\/p>\n\n\n\n
Children<\/strong><\/p>\n\n\n\nSafety and efficacy in children (under 6 years of age) have not been studied. Therefore, this medicine is not recommended for children under 6 years of age.<\/p>\n\n\n\n
Other medicines and Renvela<\/h2>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
- You should not take Renvela at the same time as\u00a0ciprofloxacin\u00a0(an\u00a0antibiotic\u00a0).<\/li>
- If you are taking\u00a0medicines<\/em>\u00a0for heart rhythm problems or epilepsy, you should consult your doctor when taking Renvela.<\/li>
- Renvela may reduce the effects of medicines such as ciclosporin, mycophenolate mofetil, and tacrolimus (medicines used to\u00a0suppress\u00a0the immune system).\u00a0Your doctor will advise you if you are taking these medicines.<\/li>
- Thyroid hormone deficiency can be observed in less common cases in some people taking levothyroxine (used to treat low levels of thyroid hormone) and Renvela.\u00a0Therefore, your doctor may check the levels of thyroid-stimulating hormone\u00a0in your blood more closely.<\/li>
- Drugs to treat heartburn and acid reflux from your stomach or esophagus, such as omeprazole, pantoprazole, or lansoprazole, so-called “proton pump inhibitors”, may reduce the effect of Renvela.\u00a0Your doctor may want to check the phosphate levels in your blood.<\/li><\/ul>\n\n\n\n
Your doctor will regularly check the risk of Renvela being affected or affected by other medicines.<\/p>\n\n\n\n
In some cases when Renvela is to be taken while you are taking another medicine, your doctor may ask you to take the other medicine 1 hour before or 3 hours after taking Renvela. Your doctor may also want to check the levels of the other medicine in your blood.<\/p>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0The potential risk of Renvela during human pregnancy is unknown.\u00a0Talk to your doctor who will decide if you can continue treatment or not.<\/p>\n\n\n\n
It is unknown if Renvela can pass into breast milk and affect your baby.\u00a0Talk to your doctor who will decide if you can breastfeed or not and if it is necessary to stop taking Renvela.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Renvela is unlikely to affect your ability to drive or use machines.<\/p>\n\n\n\n
Excipients<\/h2>\n\n\n\n
This medicine contains less than 1 mmol sodium (23 mg) per tablet, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
How to take Renvela<\/h2>\n\n\n\n
Always take Renvela exactly as your doctor has told you. Your doctor will base dose one on your serum phosphorus level.<\/p>\n\n\n\n
The recommended starting dose of Renvela tablets for adults and the elderly is one to two tablets of 800 mg at each meal, ie 3 times a day.\u00a0If you are not sure, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n
Take Renvela after a meal or with food.<\/p>\n\n\n\n
The tablets must be swallowed whole.\u00a0They must not be crushed, chewed, or split.<\/p>\n\n\n\n
In the beginning, the doctor will check the phosphorus levels in your blood at 2-4 week intervals and may adjust Renvelados one if necessary to achieve a suitable phosphate level.<\/p>\n\n\n\n
Follow the diet prescribed by your doctor.<\/p>\n\n\n\n
If you take more Renvela than you should<\/h2>\n\n\n\n
In the event of an overdose, contact your doctor immediately.<\/p>\n\n\n\n
If you forget to take Renvela<\/h2>\n\n\n\n
If you have missed a\u00a0dose, skip this\u00a0dose\u00a0and take the next\u00a0dose\u00a0at regular meal times.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n
If you stop taking Renvela<\/h2>\n\n\n\n
Taking Renvela treatment is important to maintain an appropriate level of phosphate in your blood. Quitting Renvela would lead to significant consequences such as calcification of the blood vessels. If you are considering stopping treatment with Renvela, contact your doctor or pharmacist first.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Constipation is a very common side effect (may affect more than 1 in 10 people). It can be an early symptom of intestinal blockage. In case of constipation, you should contact a doctor or pharmacist.<\/p>\n\n\n\n
Some\u00a0side effects\u00a0can be serious.\u00a0If you get any of the following\u00a0side effects, seek immediate medical attention:<\/p>\n\n\n\n
- Allergic reaction\u00a0(symptoms include rash, hives, swelling, and difficulty breathing).\u00a0This is a very rare\u00a0side effect\u00a0(may affect up to 1 in 10,000 people).<\/li>
- Intestinal blockage (symptoms include severe bloating (abdominal pain, swelling, or cramps), and severe constipation) have been reported.\u00a0No known frequency (frequency can not be calculated from available data).<\/li>
- Holes in the intestinal wall (symptoms include severe abdominal pain, chills, fever, nausea, vomiting, or sore abdomen).\u00a0No known frequency.<\/li>
- Severe\u00a0inflammation\u00a0of the colon (symptoms include severe abdominal pain, gastrointestinal upset or blood in the stool (\u00a0gastrointestinal\u00a0bleeding)), and deposition of sevelamer crystals in the intestinal mucosa have been reported.\u00a0No known frequency.<\/li><\/ul>\n\n\n\n
Other side effects have been reported in patients taking Renvela:<\/p>\n\n\n\n
Very common:<\/strong>
vomiting, pain in the upper abdomen, nausea<\/p>\n\n\n\nCommon (may affect up to 1 in 10 people):<\/strong>
diarrhea, stomach pain, indigestion, flatulence<\/p>\n\n\n\nNo known frequency:<\/strong>
cases of\u00a0pruritus, rash, slow bowel motility (mobility)<\/p>\n\n\n\nHow to store Renvela<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the can and carton after \u201cEXP\u201d. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Close the jar tightly. Moisture sensitive.<\/p>\n\n\n\n
No special storage instructions.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is sevelamer carbonate.\u00a0One film-coated tablet contains 800 mg of sevelamer carbonate<\/li>
- The other ingredients are microcrystalline cellulose, sodium chloride, and zinc stearate.\u00a0The tablet coating contains hypromellose (E464) and diacetylated\u00a0monoglycerides.\u00a0The label ink contains black iron oxide (E172), isopropyl alcohol, and propylene glycol.<\/li><\/ul>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Renvela film-coated tablets are white tablets with “Renvela 800” embossed on one side.\u00a0The tablets are packaged in high-density polyethylene cans with a polypropylene cap and induction seal.<\/p>\n\n\n\n
Pack sizes :
Each jar contains 30 tablets or 180 tablets.<\/p>\n\n\n\n
Packs of 1 can with 30 or 180 tablets (without outer carton) and aultiple packs containing 180 (6 cans of 30) tablets.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Genzyme Europe BV<\/p>\n\n\n\n
Paasheuvelweg 25
1105 BP Amsterdam<\/p>\n\n\n\n
Netherlands<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\n
Genzyme Ireland Limited
IDA Industrial Park
Old Kilmeaden Road
Waterford
Ireland<\/p>\n\n\n\n
Contact the representative of the marketing authorization holder to find out more about this medicine.<\/p>\n\n\n\n
Sanofi AB<\/p>\n\n\n\n
Tel: +46 (0) 8 634 50 00<\/p>\n","protected":false},"excerpt":{"rendered":"
Renvela contains sevelamer carbonate as the active substance. It binds phosphate from the food in the digestive tract and thus lowers the serum levels of phosphorus in the blood.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22711,22715,22714,22706,22710,22709,22712,22707,22713,22708],"class_list":["post-21920","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-renvela","tag-renvela-side-effects","tag-renvela-tablet","tag-sevelamer-carbonate","tag-sevelamer-carbonate-side-effects","tag-sevelamer-carbonate-tablet","tag-what-is-renvela","tag-what-is-sevelamer-carbonate","tag-what-renvela-is-used-for","tag-what-sevelamer-carbonate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21920"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21920\/revisions"}],"predecessor-version":[{"id":21947,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21920\/revisions\/21947"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}