{"id":21914,"date":"2022-06-14T07:44:00","date_gmt":"2022-06-14T07:44:00","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21914"},"modified":"2022-06-14T13:21:25","modified_gmt":"2022-06-14T13:21:25","slug":"renitec","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/renitec\/","title":{"rendered":"Renitec &#8211; Enalapril maleate uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg, 5 mg, 10 mg and 20 mg&nbsp;tablets<br>of enalapril maleate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Renitec is and what it is used for<\/h2>\n\n\n\n<p>Renitec contains an active substance called enalapril maleate.\u00a0Renitec belongs to a group of medicines called ACE inhibitors (\u00a0angiotensin-converting\u00a0enzymes).<\/p>\n\n\n\n<p>Renitec is used:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>to treat high\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0)<\/li><li>to treat\u00a0heart failure\u00a0(impaired heart function).\u00a0Renitec may reduce the need for hospitalization and may, for some, lead to prolonged survival<\/li><li>to reduce the symptoms of\u00a0heart failure.\u00a0Symptoms include shortness of breath, and fatigue after light physical activity such as walking, or swelling of the ankles and feet.<\/li><\/ul>\n\n\n\n<p>This medicine works by dilating your blood vessels and this lowers your blood\u00a0pressure.\u00a0The drug usually has an effect within an hour and the effect lasts for at least 24 hours.\u00a0Some individuals may need several weeks of treatment before the optimal effect on\u00a0blood pressure\u00a0is achieved.<\/p>\n\n\n\n<p>Enalapril maleate contained in Renitec may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Renitec<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Renitec:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0enalapril\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have previously had an\u00a0allergic reaction\u00a0to a medicine belonging to the same group as this medicine, a so-called\u00a0ACE inhibitor<\/li><li>if you have previously experienced swelling of the face, lips, mouth, tongue, or throat which caused difficulty swallowing and\/or breathing (\u00a0angioedema\u00a0) of unknown cause or in hereditary\u00a0angioedema<\/li><li>if you have\u00a0diabetes\u00a0or renal impairment and are being treated with a blood pressure-lowering medicine containing aliskiren<\/li><li>during the last 6 months of pregnancy.\u00a0(Even earlier in pregnancy, it is good to avoid Renitec, see Pregnancy and breast-feeding)<\/li><li>if you have taken or are currently taking sacubitril\/valsartan, a medicine used to treat a type of chronic (\u00a0chronic\u00a0)\u00a0heart failure in adults, it increases the risk of\u00a0angioedema\u00a0(rapid swelling under the skin in an area such as the throat).<\/li><\/ul>\n\n\n\n<p>Do not take this medicine if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Renitec:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have heart problems<\/li><li>if you suffer from any disease that affects the blood vessels in the brain<\/li><li>if you have a blood disorder such as low blood cell count or lack of\u00a0white blood cells\u00a0(neutropenia\/agranulocytosis), low\u00a0platelet count\u00a0(\u00a0thrombocytopenia\u00a0), or decreased\u00a0red blood cell count\u00a0(\u00a0anemia\u00a0)<\/li><li>if you have liver problems<\/li><li>if you have any kidney disease (including kidney transplantation), are on a low-salt diet, are being treated with potassium supplements, potassium-sparing agents, potassium-containing salt substitutes, or other medicines that may increase the level of potassium in your blood (eg\u00a0heparin\u00a0[a medicine used to prevent blood clots], medicines containing trimethoprim such as the combination trimethoprim\/sulfamethoxazole [medicines used to treat\u00a0infections\u00a0]).\u00a0This can lead to elevated levels of\u00a0potassium\u00a0in the blood which can be serious.\u00a0Your doctor may need to adjust your\u00a0dose\u00a0of Renitec or check your blood potassium levels.\u00a0See also information under the heading &#8220;Other medicines and Renitec&#8221;<\/li><li>if you are undergoing\u00a0dialysis<\/li><li>if you have recently had severe vomiting or diarrhea<\/li><li>if you have\u00a0diabetes.\u00a0You should monitor your blood sugar levels, especially during the first month of treatment.\u00a0Potassium\u00a0levels\u00a0in the blood can also increase<\/li><li>if you have previously had an\u00a0allergic reaction\u00a0with swelling of the face, lips, tongue, or throat with difficulty swallowing and\/or breathing.\u00a0You should be aware that black patients are at increased risk for these types of reactions with ACE inhibitors<\/li><li>if you have low\u00a0blood pressure\u00a0(you may experience weakness or dizziness, especially when standing up)<\/li><li>if you have a\u00a0collagenous\u00a0vascular\u00a0disease (lupus erythematosus,\u00a0rheumatoid arthritis,\u00a0or scleroderma), are on\u00a0immunosuppressive\u00a0therapy, treated with allopurinol or\u00a0procainamide, or a combination of these<\/li><li>if you are taking any of the following medicines, the risk of\u00a0angioedema\u00a0may be increased:<ul><li>racecadotril, a medicine used to treat diarrhea<\/li><li>drugs used to prevent rejection of transplanted organs and against cancer (eg <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/torisel\/\">temsirolimus<\/a>, sirolimus, everolimus)<\/li><li>vildagliptin, a medicine used to treat\u00a0diabetes<\/li><\/ul><\/li><li>if you are taking any of the following medicines used to treat high blood pressure:<ul><li>an\u00a0angiotensin\u00a0II receptor blocker (ARB) (also known as sartans &#8211; for example, valsartan, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tolura\/\">telmisartan<\/a>, irbesartan), especially if you have diabetes-related kidney problems<\/li><li>aliskiren.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Your doctor may need to check your kidney function,\u00a0blood pressure, and the number of\u00a0electrolytes\u00a0(eg\u00a0potassium\u00a0) in your blood at regular intervals.<\/p>\n\n\n\n<p>See also the information under the heading &#8220;Do not take Renitec&#8221;.<\/p>\n\n\n\n<p>Contact your doctor if you think you are (or might become) pregnant.&nbsp;This medicine is not recommended during early pregnancy and should not be used during the last 6 months of pregnancy as it may cause fetal harm (see Pregnancy).<\/p>\n\n\n\n<p>You should be aware that this medicine does not lower&nbsp;blood pressure&nbsp;as effectively in black patients.<\/p>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<p><strong>If you are going to undergo a treatment<\/strong><\/p>\n\n\n\n<p>Tell them you are taking Renitec if you are going to undergo any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a surgical procedure or if you are going to undergo anesthesia (even at the dentist)<\/li><li>a treatment to remove\u00a0cholesterol\u00a0in the blood called\u00a0LDL\u00a0-apheresis<\/li><li>a\u00a0hyposensitization, to reduce hypersensitivity to bee or wasp stings.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you, talk to your doctor or dentist before taking Renitec.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Renitec<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This also applies to (traditional) herbal medicines and herbal medicines.\u00a0Renitec can affect the way other medicines work in the body and some other medicines can also affect the way Renitec works in the body.\u00a0Your doctor may need to change your\u00a0dose\u00a0and\/or take other precautions.<\/p>\n\n\n\n<p>It is especially important to tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>an\u00a0angiotensin\u00a0II receptor blocker (ARB) or aliskiren (see also the information under the headings \u201cDo not take Renitec\u201d and \u201cWarnings and precautions\u201d)<\/li><li>other antihypertensive drugs such as beta-blockers or\u00a0diuretics\u00a0(\u00a0diuretics\u00a0)<\/li><li>potassium supplements (including salt substitutes), potassium-sparing\u00a0diuretics,\u00a0and other drugs that can increase the amount of\u00a0potassium\u00a0in your blood (eg trimethoprim and the combination trimethoprim\/sulfamethoxazole for\u00a0infection\u00a0caused by bacteria; ciclosporin, an immune-boosting drug used to prevent rejection of transplanted organs, and\u00a0heparin, a blood-thinning drug used to prevent blood clots).\u00a0See also information under the heading &#8220;Warnings and precautions&#8221;.<\/li><li>antidiabetic\u00a0drugs\u00a0(including oral antidiabetic drugs and\u00a0insulin\u00a0)<\/li><li>lithium (a medicine used to treat a certain type of depression)<\/li><li>antidepressants so-called\u00a0tricyclic\u00a0antidepressants<\/li><li>medicines for mental disorders called antipsychotics<\/li><li>certain medicines for coughs and colds and for weight loss which contain something called\u00a0sympathomimetic<\/li><li>certain medicines for pain or rheumatism including gold therapy<\/li><li>an inhibitor of mTOR (eg temsirolimus, sirolimus, everolimus &#8211; medicines used to treat certain types of cancer or to prevent the body&#8217;s immune system from rejecting a transplanted organ).\u00a0See also information under the heading &#8220;Warnings and precautions&#8221;<\/li><li>a drug containing a neprilysin inhibitor such as sacubitril (available as a combination with valsartan), racecadotril, or vildagliptin.\u00a0The risk of\u00a0angioedema\u00a0(swelling of the face, lips, tongue, or throat with difficulty swallowing or breathing) may increase.\u00a0See also the information under the headings &#8220;Do not take Renitec&#8221; and &#8220;Warnings and precautions&#8221;.<\/li><li>non-steroidal anti-inflammatory drugs, including\u00a0COX-2\u00a0inhibitors (drugs that reduce inflammation and can be used to relieve pain)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/treo-comp\/\">aspirin<\/a> (\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>\u00a0)<\/li><li>drugs used to dissolve blood clots (\u00a0thrombolytics\u00a0)<\/li><li>alcohol.<\/li><\/ul>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking Renitec.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Renitec with food and drink<\/h2>\n\n\n\n<p>Renitec can be taken with or without food.&nbsp;Most people take Renitec with a glass of water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.\u00a0Usually, your doctor will suggest that you stop taking Renitec before pregnancy or as soon as you know you are pregnant and instead recommend another medicine for you.\u00a0This medicine should not be used in early pregnancy and should not be used during the last 6 months of pregnancy as it may cause birth defects.<\/p>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<p>Tell your doctor if you are breastfeeding or planning to start breastfeeding.\u00a0This medicine is not recommended for breastfeeding, especially if your baby is a newborn (the first few weeks after birth) or was born prematurely.\u00a0In the case of an older child, your doctor may advise you on the benefits and risks of taking this medicine while breastfeeding compared to other treatments.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may experience dizziness or drowsiness while taking this medicine.&nbsp;If you experience this, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Renitec contains lactose and sodium<\/h2>\n\n\n\n<p><strong>Renitec contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p>Renitec contains\u00a0lactose, which is a sugar.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Renitec contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.&nbsp;is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Renitec<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You must continue to take this medicine as\u00a0prescribed by your doctor<\/li><li>Do not take more tablets than you have been prescribed<\/li><li>the notch is only for you to be able to divide the tablet if you have difficulty swallowing it whole.<\/li><\/ul>\n\n\n\n<p><strong>High&nbsp;blood pressure<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The usual starting dose varies from 5 mg to 20 mg once daily.<\/li><li>Some patients may need a lower starting dose.<\/li><li>The usual maintenance dose is 20 mg once daily.<\/li><li>The maximum maintenance dose is 40 mg once daily.<\/li><\/ul>\n\n\n\n<p><strong>Heart failure<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The usual starting dose is 2.5 mg once daily.<\/li><li>Your doctor may gradually increase the\u00a0dose\u00a0until the appropriate\u00a0dose\u00a0for you is reached.<\/li><li>The usual maintenance dose is 20 mg daily, taken in one or two\u00a0doses.<\/li><li>The maximum maintenance dose is 40 mg daily, divided into two\u00a0doses.<\/li><\/ul>\n\n\n\n<p><strong>Impaired renal function<\/strong><\/p>\n\n\n\n<p>Your&nbsp;dose&nbsp;will need to be adjusted depending on how well your kidneys are working:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>moderate renal impairment &#8211; 5 mg to 10 mg daily<\/li><li>severely impaired renal function &#8211; 2.5 mg daily<\/li><li>if you are on\u00a0dialysis\u00a0&#8211; 2.5 mg daily.\u00a0On days when you do not undergo\u00a0dialysis, your\u00a0dose\u00a0may need to be adjusted depending on how low your\u00a0blood pressure\u00a0is.<\/li><\/ul>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>Your doctor will decide which&nbsp;dose&nbsp;to take and it is based on how well your kidneys are working.<\/p>\n\n\n\n<p><strong>Use for children<\/strong><\/p>\n\n\n\n<p>Experience with the use of Renitec in children with high\u00a0blood pressure\u00a0is limited.\u00a0If the child can swallow tablets, the\u00a0dose\u00a0is calculated based on weight and\u00a0blood pressure.\u00a0The usual starting dose is:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>between 20 kg and 50 kg &#8211; 2.5 mg daily<\/li><li>more than 50 kg &#8211; 5 mg daily.<\/li><\/ul>\n\n\n\n<p>Dose&nbsp;one can be adjusted depending on the child&#8217;s needs:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>maximum&nbsp;dose&nbsp;of 20 mg daily in children weighing between 20 kg and 50 kg<\/li><li>maximum&nbsp;dose&nbsp;of 40 mg daily in children weighing more than 50 kg.<\/li><\/ul>\n\n\n\n<p>This medicine is not recommended for newborns (the first weeks after birth) or children with kidney problems.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Renitec than you should<\/h2>\n\n\n\n<p>If you take more Renitec than you should, talk to your doctor or see a hospital immediately.&nbsp;Take the medicine pack with you.&nbsp;The most likely symptoms are fainting or dizziness.&nbsp;This is due to a sudden or severe drop in blood pressure.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Renitec<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a tablet, skip the missed\u00a0dose.<\/li><li>Take the next\u00a0dose\u00a0as usual.<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Renitec<\/h2>\n\n\n\n<p>Do not stop taking Renitec unless your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<p><strong>If any of these&nbsp;side effects&nbsp;occur, stop taking Renitec and contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, lips, tongue, or throat, which may cause breathing and\/or swallowing difficulties<\/li><li>swelling of hands, feet, or ankles<\/li><li>if you develop raised red skin rashes (\u00a0hives\u00a0).<\/li><\/ul>\n\n\n\n<p>You should be aware that black patients are at increased risk for these types of reactions.&nbsp;If any of the above occur, stop taking Renitec and contact your doctor immediately.<\/p>\n\n\n\n<p>When you start taking this medicine, you may experience fainting or dizziness.\u00a0If this happens, it helps to lie down.\u00a0This is caused by a drop in\u00a0blood pressure.\u00a0It improves if you continue to take the medicine.\u00a0If you have any concerns, talk to your doctor.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;include:<\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness, weakness, or malaise<\/li><li>dimsyn<\/li><li>cough.<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness due to low\u00a0blood pressure, changes in heart rate, palpitations, angina or chest pain<\/li><li>headache, depression, fainting (\u00a0syncope\u00a0), taste changes<\/li><li>respiratory distress<\/li><li>diarrhea, abdominal pain,<\/li><li>fatigue<\/li><li>skin rash, allergic reactions with swelling of the face, lips, tongue, or throat with difficulty swallowing and\/or breathing<\/li><li>high levels of\u00a0potassium\u00a0in the blood, and increased levels of\u00a0creatinine\u00a0in the blood (both are usually detected by a blood test).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>redness<\/li><li>a sudden drop in blood pressure<\/li><li>fast or uneven heartbeat (palpitations)<\/li><li>myocardial infarction (possibly due to low\u00a0blood pressure\u00a0in some high-risk patients including patients with blood flow disorders in the heart or brain)<\/li><li>stroke\u00a0(possibly due to low\u00a0blood pressure\u00a0in high-risk patients)<\/li><li>anemia\u00a0(including aplastic and hemolytic)<\/li><li>confusion, insomnia or drowsiness, nervousness<\/li><li>stinging or numb feeling in the skin<\/li><li>dizziness (fraud)<\/li><li>ringing in the ears (\u00a0tinnitus\u00a0)<\/li><li>runny nose, sore throat, or hoarseness<\/li><li>asthma, associated tightness in the chest<\/li><li>delayed intestinal passage (intestinal knot),\u00a0inflammation\u00a0of the pancreas<\/li><li>nausea (vomiting), indigestion, constipation,\u00a0anorexia<\/li><li>irritated stomach (irritation of the stomach),\u00a0dry mouth,\u00a0stomach ulcers<\/li><li>muscle cramps<\/li><li>renal impairment,\u00a0renal failure<\/li><li>increased sweating<\/li><li>itching\u00a0or\u00a0hives<\/li><li>hair loss<\/li><li>general malaise, fever,\u00a0impotence<\/li><li>high level of\u00a0protein\u00a0in the urine (measured in a test)<\/li><li>low blood sugar or low level of\u00a0sodium\u00a0in the blood, and high level of\u00a0urea\u00a0in the blood (all measured by a blood test).<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>&#8220;Raynaud&#8217;s phenomenon&#8221; where your hands and feet can become very cold and white due to low blood flow<\/li><li>changes in blood values \u200b\u200bsuch as low white and\u00a0red blood cell count, low hemoglobin value, lower\u00a0platelet count<\/li><li>bone marrow depression<\/li><li>swollen\u00a0glands\u00a0in the neck, armpits, or groin<\/li><li>autoimmune diseases<\/li><li>strange dreams or difficulty sleeping<\/li><li>accumulation of fluid or other substances in the lungs (which can be seen on X-ray)<\/li><li>inflammation\u00a0of the nose<\/li><li>inflammation\u00a0of the lungs that causes difficulty breathing (\u00a0pneumonia\u00a0),\u00a0inflammation\u00a0of the cheeks, gums, tongue, lips, throat<\/li><li>reduced urine output<\/li><li>circular rash (erythema multiforme)<\/li><li>&#8220;Stevens-Johnson syndrome&#8221; and &#8220;toxic\u00a0epidermal\u00a0necrolysis&#8221; (severe skin conditions with\u00a0redness\u00a0and scaling of the skin, blisters, or sores) exfoliative dermatitis\/erythroderma (severe rash with flaking or flaking of the skin),\u00a0pemphigus\u00a0(small fluid-filled bumps on the skin)<\/li><li>liver problems or problems with the gallbladder such as hepatic impairment,\u00a0inflammation\u00a0of the liver, jaundice (yellowing of the skin and eyes), high levels of liver enzymes and bilirubin (measured in a blood test)<\/li><li>breast augmentation in men (\u00a0gynecomastia\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the intestine (intestinal&nbsp;angioedema&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(can not be calculated from the available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>overproduction of\u00a0the antidiuretic hormone, which causes\u00a0fluid retention\u00a0and leads to weakness, fatigue, or confusion<\/li><li>a symptom complex has been reported which may include some or all of the following: fever,\u00a0inflammation\u00a0of the blood vessels (serositis\/vasculitis), muscle pain (myalgia\/myositis), joint pain (arthralgia\/arthritis).\u00a0Rash,\u00a0photosensitivity,\u00a0or other skin changes may occur.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Renitec<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister card or the carton after &#8220;EXP&#8221; and &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is enalapril maleate (2.5 mg, 5 mg, 10 mg, and 20 mg respectively).<\/li><li>The other ingredients are\u00a0lactose monohydrate, sodium bicarbonate, corn starch, pregelatinized\u00a0starch, and magnesium stearate.\u00a0The 10 mg tablet also contains red iron oxide (E172) and the 20 mg tablet also contains red iron oxide (E172) and yellow iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Renitec 2.5 mg: white, round, with one side marked MSD 14 and the other side smooth.<\/p>\n\n\n\n<p>Renitec 5 mg: white, rounded triangular, with one side, notched and the other side marked MSD 712.<\/p>\n\n\n\n<p>Renitec 10 mg: rust red, rounded triangular, with one side-notched and the other side marked MSD 713.<\/p>\n\n\n\n<p>Renitec 20 mg: peach-colored, rounded triangular, with one side, notched and the other side marked MSD 714.<\/p>\n\n\n\n<p>The breaker is not for dividing the tablet into equal\u00a0doses, but only for easier swallowing.<\/p>\n\n\n\n<p>Renitec is available in the following pack sizes:<\/p>\n\n\n\n<p>Renitec 2.5 mg: Aluminum \/ aluminum blister pack containing 2, 11, 20, 28, 30, 40, 49&#215;1, 50 or 100 tablets.<\/p>\n\n\n\n<p>Renitec 5 mg: Aluminum \/ aluminum blister pack containing 2, 14, 20, 28, 28&#215;1, 30, 49&#215;1, 50, 56, 98 or 100 tablets.<\/p>\n\n\n\n<p>Renitec 10 mg: Aluminum \/ aluminum blister pack containing 28, 49&#215;1, 30, 50, 98 or 100 tablets.<\/p>\n\n\n\n<p>Renitec 20 mg: Aluminum \/ aluminum blister pack containing 10, 14, 20, 28, 28&#215;1, 30, 49&#215;1, 50, 56, 60, 84, 90, 98, 100 or 500 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><em>Marketing Authorization Holder: <\/em>NV OrganonKloosterstraat 65349 AB OssNetherlands<\/td><td>&nbsp;<\/td><\/tr><tr><td><strong>Manufacturer<\/strong>Merck Sharp &amp; Dohme BVPO Box 5812003 PC Haarlem Netherlands<\/td><td><\/td><\/tr><tr><td>Schering-Plow Labo NVIndustrial Park 30Heist-op-den-Berg, 2220Belgium<\/td><td><\/td><\/tr><tr><td><strong>Local representative:<\/strong>Organon Sweden ABTel: +46 8 502 597 00 dpoc.sweden@organon.com<\/td><td>&nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>This medicine is authorized in the European Economic Area<\/strong><\/p>\n\n\n\n<p><strong>and in the United Kingdom (Northern Ireland) under the names:<\/strong><\/p>\n\n\n\n<p>Austria, Belgium, Finland, France, Greece, Luxembourg, Netherlands, Portugal, Spain, Sweden: UNITEC<\/p>\n\n\n\n<p>Germany: XANEF<\/p>\n\n\n\n<p>Italy: ENAPREN<\/p>\n\n\n\n<p>United Kingdom (Northern Ireland), Ireland: INNOVATE<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Renitec contains an active substance called enalapril maleate. Renitec belongs to a group of medicines called ACE inhibitors ( angiotensin converting enzyme ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22728,4280,4282,4283,22729,22733,22732,16070,22730,22731],"class_list":["post-21914","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-enalapril-maleate","tag-enalapril-maleate","tag-enalapril-maleate-side-effects","tag-enalapril-maleate-tablet","tag-renitec","tag-renitec-side-effects","tag-renitec-tablet","tag-what-enalapril-maleate-is-used-for","tag-what-is-renitec","tag-what-renitec-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21914"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21914\/revisions"}],"predecessor-version":[{"id":21950,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21914\/revisions\/21950"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}