{"id":21912,"date":"2022-06-14T07:42:35","date_gmt":"2022-06-14T07:42:35","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21912"},"modified":"2022-06-14T13:21:32","modified_gmt":"2022-06-14T13:21:32","slug":"renapur","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/renapur\/","title":{"rendered":"Renapur &#8211; Potassium sodium hydrogen citrate uses, dose and side effects"},"content":{"rendered":"\n<p>granules<br>potassium sodium hydrogen citrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Renapur is and what it is used for<\/h2>\n\n\n\n<p>Renapur is used to dissolve uric acid stones and to prevent the formation of new ones.&nbsp;Renapur is used on&nbsp;prescription&nbsp;from a doctor.<\/p>\n\n\n\n<p>Renapur works by dissolving stones of\u00a0uric acid\u00a0or its salts.\u00a0Normally, the uric acid follows the urine out of the body.\u00a0A stone is formed only when the uric acid crystallizes out, ie when its solubility in the urine decreases.\u00a0This is affected by the\u00a0pH\u00a0of the urine.<\/p>\n\n\n\n<p>The pH\u00a0value is a measure that indicates whether a solution is acidic or\u00a0alkaline.\u00a0A pH\u00a0value of 7 is the neutral value, a higher value means that the solution is\u00a0alkaline,\u00a0and a value below 7, is an acidic solution.<\/p>\n\n\n\n<p>The pH\u00a0value can easily be read on an indicator paper, which when dipped in a solution changes color according to\u00a0pH.<\/p>\n\n\n\n<p>Uric acid\u00a0dissolves poorly if the\u00a0pH\u00a0is below 6.2.\u00a0Crystals can then form and in unfavorable cases grow into stones.\u00a0A shift of the urine\u00a0pH\u00a0towards 7 improves the solubility of the uric acid and already formed stones can dissolve.\u00a0It is important that the shift of the\u00a0pH\u00a0value becomes uniform over a longer period and that the value is kept constant between 6.2 and 6.8.\u00a0This effect can be achieved with Renapur.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Renapur<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Renapur<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to potassium sodium hydrogen citrate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have high levels of\u00a0potassium\u00a0in your blood (hyperkalemia)<\/li><li>if you have poor kidney function (\u00a0acute\u00a0kidney failure\u00a0or\u00a0chronic\u00a0kidney failure\u00a0that causes you to have high levels of\u00a0potassium\u00a0in your blood)<\/li><li>if you have elevated blood\u00a0pH\u00a0(a condition called\u00a0metabolic alkalosis\u00a0)<\/li><li>if you have a\u00a0chronic\u00a0urinary tract infection with certain unusual bacteria, so-called urea-degrading bacteria\u00a0<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before using Renapur.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor if you have severe liver problems.<\/li><\/ul>\n\n\n\n<p>Before starting treatment, kidney function and levels of salts in the blood (\u00a0electrolytes, eg\u00a0potassium,\u00a0and\u00a0sodium\u00a0) should be checked by a doctor.<\/p>\n\n\n\n<p>For the treatment to be successful, it is necessary to be carefully instructed on the use of Renapur.&nbsp;Regular medical check-ups should be done throughout the treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Renapur<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Drugs that may affect or be affected by Renapur are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>potassium-sparing diuretics (eg\u00a0spironolactone\u00a0, eplerenone)<\/li><li>cardiac glycosides (eg\u00a0digoxin\u00a0)<\/li><li>potassium supplements<\/li><li>certain drugs such as\u00a0used for high\u00a0blood pressure\u00a0and\u00a0heart failure\u00a0(\u00a0ACE inhibitors\u00a0eg <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triatec\/\">ramipril<\/a>,\u00a0enalapril\u00a0or angiotensin receptor blockers eg valsartan,\u00a0losartan\u00a0)<\/li><li>certain painkillers (non-steroidal anti-inflammatory drugs, so-called\u00a0NSAIDs, eg\u00a0ibuprofen,\u00a0diclofenac,\u00a0naproxen\u00a0)<\/li><li>drugs containing aluminum, e.g.\u00a0certain antacids (medicines for heartburn and acid reflux).\u00a0Renapur and these medicines should be taken at least 2 hours apart.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Renapur is not expected to pose any risk to the fetus during recommended use.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>No effects are expected on the breastfed baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Renapur\u00a0granules\u00a0do not affect the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Renapur contains para-orange (E 110), potassium, and sodium<\/h2>\n\n\n\n<p>The dye para-orange can cause allergic reactions.<\/p>\n\n\n\n<p>This medicine contains approximately 425 mg of\u00a0potassium\u00a0per dosing spoon (1.7 g per average daily\u00a0dose\u00a0of 4 dosing spoons).\u00a0This should be considered by patients with\u00a0impaired\u00a0renal function, elderly patients, and patients on a low-potassium diet.<\/p>\n\n\n\n<p>This medicine contains approximately 250 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per dosing spoon (1 g per average daily\u00a0dose\u00a0of 4 dosing spoons).\u00a01 g corresponds to 50% of the WHO&#8217;s highest recommended daily intake of\u00a0sodium\u00a0for adults.\u00a0Talk to your doctor or pharmacist if you need more than one tablespoon daily for an extended period, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Renapur<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dosage\u00a0one is individual and should always be done according to the doctor&#8217;s\u00a0prescription.<\/p>\n\n\n\n<p>Dosage&nbsp;one of Renapur should be adjusted so that the uric acid gets its desired&nbsp;pH value&nbsp;between 6.2 and 6.8.&nbsp;Dose&nbsp;one is increased if the&nbsp;pH&nbsp;during the day falls below 6.2 and decreases if the value exceeds 6.8.<\/p>\n\n\n\n<p>In otherwise healthy persons, the urine&nbsp;pH&nbsp;is increased by 0.2 of 1.25 g Renapur (approx. \u00bd dosing spoon).<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;is 4 ironed dosing spoons per day (10 g&nbsp;granules&nbsp;) divided into 3 dosing times according to the dosing table.&nbsp;The granules&nbsp;are stirred into a liquid such as water or juice and taken immediately.&nbsp;Dose&nbsp;and take after meals.<\/p>\n\n\n\n<p><strong>Dosage table<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong><em>Dosing occasion<\/em><\/strong><\/td><td><strong><em>Quantity<\/em><\/strong><strong><em>dosing&nbsp;<\/em><\/strong><strong><em>spoons of 2.5 g<\/em><\/strong><\/td><\/tr><tr><td>In the morning after breakfast<\/td><td>1<\/td><\/tr><tr><td>In the middle of the day after lunch<\/td><td>1<\/td><\/tr><tr><td>In the evening after the meal as late as possible<\/td><td>2<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The effect of the treatment is always measured three times a day before the next\u00a0dose\u00a0by measuring the\u00a0pH\u00a0of the urine, see under\u00a0<strong>Instructions for use.<\/strong><\/p>\n\n\n\n<p><strong>Instructions for use<\/strong><\/p>\n\n\n\n<p>The indicator paper consists of about 100 yellow-brown paper strips and a color scale.<\/p>\n\n\n\n<p>The pH\u00a0is checked before each new\u00a0dose.\u00a0Tear off an indicator paper and moisten in fresh urine.\u00a0The indicator paper now changes color tone and is immediately compared with the color scale.<\/p>\n\n\n\n<p>The value below the color tone that corresponds to the indicator paper is recorded in the control calendar.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19701218000018#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Meda\/Media\/Renapur\/Bruksanvisning20dosering20Renapur20GIF.jpg\" alt=\"Instructions for use for interpretation of indicator paper\" title=\"Instructions for use for interpretation of indicator paper\"\/><\/a><\/figure>\n\n\n\n<p>Then a new&nbsp;dose&nbsp;of Renapur is taken and the number of spoons is noted in the control calendar.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>There is no dose recommendation for children and adolescents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Renapur than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>Taking too much Renapur can lead to high levels of\u00a0potassium\u00a0in the blood (hyperkalemia).\u00a0Muscle weakness, nausea, diarrhea, and irregular heartbeat can be signs of greatly elevated\u00a0potassium\u00a0in the blood.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Renapur<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;abdominal pain.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em>&nbsp;diarrhea, nausea.<\/p>\n\n\n\n<p>There is a risk of the formation of phosphate stones in&nbsp;alkaline&nbsp;urine, so the&nbsp;pH&nbsp;must not exceed 6.8.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Renapur<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Used before the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is potassium sodium hydrogen citrate.&nbsp;100 g of&nbsp;granules&nbsp;contain potassium sodium hydrogen citrate (6: 6: 3: 5) 97.108 g.<\/li><li>The other ingredients are para-orange (dye E 110) and lemon oil.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Plastic jars with 280 grams.<\/p>\n\n\n\n<p>The package also contains a dosing spoon, control calendar, and indicator paper.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Meda AB<\/p>\n\n\n\n<p>Box 906<\/p>\n\n\n\n<p>170 09 Solna<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Renapur is used to dissolve uric acid stones and to prevent the formation of new ones. Renapur is used on prescription from a doctor.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22738,22743,22734,22737,22739,22742,22735,22740,22736,22741],"class_list":["post-21912","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-potassium-sodium-hydrogen-citrate","tag-benefits-of-renapur","tag-potassium-sodium-hydrogen-citrate","tag-potassium-sodium-hydrogen-citrate-side-effects","tag-renapur","tag-renapur-side-effects","tag-what-is-potassium-sodium-hydrogen-citrate","tag-what-is-renapur","tag-what-potassium-sodium-hydrogen-citrate-is-used-for","tag-what-renapur-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21912","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21912"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21912\/revisions"}],"predecessor-version":[{"id":21951,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21912\/revisions\/21951"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21912"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21912"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21912"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}