{"id":21840,"date":"2022-06-10T11:13:41","date_gmt":"2022-06-10T11:13:41","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21840"},"modified":"2022-06-10T12:22:44","modified_gmt":"2022-06-10T12:22:44","slug":"relenza","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/relenza\/","title":{"rendered":"Relenza &#8211; Zanamivir uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg\/dose,\u00a0inhalation powder,\u00a0divided\u00a0dose<br>zanamivir<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Relenza is and what it is used for<\/h2>\n\n\n\n<p>Relenza contains zanamivir, which belongs to a group of medicines called\u00a0<em>antivirals<\/em>.\u00a0<strong>Relenza is used to treat\u00a0flu\u00a0<\/strong>(\u00a0<em>flu virus infection<\/em>\u00a0).\u00a0It reduces flu symptoms and helps you recover faster.<\/p>\n\n\n\n<p>Relenza is also used to prevent&nbsp;flu&nbsp;during an ongoing flu epidemic.<\/p>\n\n\n\n<p>Adults and children 5 years and older can be treated with Relenza.<\/p>\n\n\n\n<p>Relenza should be inhaled (inhaled) directly into the lungs as it is not absorbed by the body when swallowed.\u00a0The influenza virus infects the lungs and therefore Relenza acts\u00a0directly on the\u00a0virus\u00a0in the lungs after\u00a0inhalation.<\/p>\n\n\n\n<p><strong>Relenza does not replace flu vaccination<\/strong>.\u00a0You still need to talk to your doctor about the need for\u00a0flu\u00a0vaccination.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Relenza<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Relenza<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you are allergic<\/strong>&nbsp;to zanamivir or any of the other ingredients of this medicine (listed in section 6).<\/li><li><strong>if you have a milk protein allergy<\/strong>&nbsp;(see \u201cRelenza contains&nbsp;lactose&nbsp;and milk protein\u201d and section 6).<\/li><\/ul>\n\n\n\n<p><strong>Do not give Relenza to children under 5 years of age.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with Relenza<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you feel tight in the throat or feel pressure over your chest when using Relenza.<\/strong><\/li><\/ul>\n\n\n\n<p>In very rare cases, Relenza may cause reactions such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>tightness in the throat or pressure over the chest<\/strong><\/li><li><strong>difficulty breathing.<\/strong><\/li><\/ul>\n\n\n\n<p>If any of these symptoms occur while you are using Relenza:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>stop taking Relenza and seek medical help immediately.&nbsp;<\/strong>Contact a doctor or the nearest emergency department for advice.<\/li><\/ul>\n\n\n\n<p><strong>If you have&nbsp;asthma&nbsp;or other lung or respiratory problems<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>asthma<\/strong><\/li><li><strong>another lung disease<\/strong> that causes breathing problems, e.g.\u00a0emphysema,\u00a0chronic obstructive pulmonary disease\u00a0(COPD), or\u00a0chronic\u00a0bronchitis<strong>.<\/strong><\/li><li><strong>Talk to your doctor before using Relenza<\/strong>\u00a0for close monitoring and monitoring of your condition.<\/li><\/ul>\n\n\n\n<p><strong>If you are taking medicines for&nbsp;inhalation<\/strong>&nbsp;for your&nbsp;asthma&nbsp;or other respiratory problems, you should carefully read the text below &#8221;&nbsp;<em>Using Relenza for concomitant treatment with inhaled medicines for respiratory problems<\/em>&nbsp;&#8221; before using Relenza.<\/p>\n\n\n\n<p><strong>Use of Relenza during concomitant treatment with inhaled medicinal products for respiratory distress<\/strong><\/p>\n\n\n\n<p><strong>If you are taking medicines for&nbsp;inhalation<\/strong>&nbsp;for&nbsp;asthma&nbsp;or other respiratory problems, continue with this as before. If you have been prescribed Relenza for the same time of day as you are taking your second inhalation medicine,&nbsp;<strong>take the other medicine a few minutes before taking Relenza.&nbsp;Be sure to have your fast-acting bronchodilator medication<\/strong>&nbsp;(eg&nbsp;salbutamol&nbsp;) on hand when using Relenza.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Relenza<\/h2>\n\n\n\n<p><strong>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines,<\/strong>\u00a0including medicines obtained without a prescription.<\/p>\n\n\n\n<p><strong>If you are using inhaled medicines,<\/strong>&nbsp;e.g.&nbsp;for&nbsp;asthma&nbsp;or other respiratory problems, be sure to read the above advice.<\/p>\n\n\n\n<p><strong>If you have been advised to get vaccinated against the&nbsp;flu<\/strong><\/p>\n\n\n\n<p>You can be vaccinated at any time, even if you use Relenza to help prevent\u00a0the flu.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>If you are pregnant or breastfeeding, think you may be pregnant<\/strong><\/p>\n\n\n\n<p><strong>or planning to have children, consult your doctor before using&nbsp;<\/strong><strong>this medicine.<\/strong>&nbsp;<\/p>\n\n\n\n<p>There is only limited information on the safety of Relenza during pregnancy.&nbsp;Although to date there is no evidence that Relenza affects the unborn baby, do not use it during pregnancy unless your doctor advises you to do so.<\/p>\n\n\n\n<p>The active substance (zanamivir) may pass into breast milk and therefore you should not breastfeed while taking Relenza.\u00a0Discuss with your doctor whether you should stop or stop using Relenza or stop breastfeeding, depending on what is best for you and your baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Relenza is unlikely to affect your ability to drive or use machines.<br>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Relenza contains lactose and milk protein<\/h2>\n\n\n\n<p>Relenza contains a sugar called&nbsp;lactose&nbsp;and contains milk protein.<br>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Relenza<\/h2>\n\n\n\n<p><strong>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;<\/strong>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Relenza is a powdered medicine that is inhaled through the mouth into the lungs using an&nbsp;inhaler&nbsp;(&nbsp;<strong>Diskhaler<\/strong>&nbsp;) contained in the pack.&nbsp;The powder is packed in blisters on a&nbsp;dosing disc&nbsp;(&nbsp;<strong>Rotadisk<\/strong>&nbsp;) which is placed in the Diskhaler.<\/p>\n\n\n\n<p><strong>The drug in the dosing discs (Rotadisk) may only be inhaled using\u00a0the Diskhaler device.<\/strong><\/p>\n\n\n\n<p><strong>Do not give Relenza to children under 5 years of age.<\/strong><\/p>\n\n\n\n<p><strong>When to start treatment with Relenza<\/strong><\/p>\n\n\n\n<p><strong>If you have the\u00a0flu<\/strong>, you should, for maximum effect, start treatment with Relenza as soon as possible after you get the flu symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>adults: within 48 hours<\/strong>&nbsp;after the first symptoms<\/li><li><strong>children: within 36 hours<\/strong>&nbsp;after the first symptoms.<\/li><\/ul>\n\n\n\n<p><strong>To help prevent&nbsp;flu<\/strong><\/p>\n\n\n\n<p><strong>In case of&nbsp;flu&nbsp;in your family, after contacting this person, you should use Relenza as soon as possible to help prevent the flu:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>adults and children: within 36 hours<\/strong>&nbsp;after contact with the infected person.<\/li><\/ul>\n\n\n\n<p><strong>In case of\u00a0flu\u00a0in your area<\/strong>, follow your doctor&#8217;s advice on when to start treatment with Relenza.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The amount of Relenza you take varies depending on whether you have the\u00a0flu\u00a0or whether you use Relenza to help prevent\u00a0the flu.<\/p>\n\n\n\n<p><strong>Treatment of&nbsp;influenza<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults and children 5 years and older:<\/strong>&nbsp;The usual&nbsp;dose&nbsp;is 2&nbsp;inhalations&nbsp;(2 blisters) twice daily for 5 days.<\/li><\/ul>\n\n\n\n<p><strong>To help prevent\u00a0flu\u00a0(\u00a0flu\u00a0in the family)<\/strong>.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults and children 5 years and older:<\/strong>&nbsp;The usual&nbsp;dose&nbsp;is 2&nbsp;inhalations&nbsp;(2 blisters) once daily for 10 days.<\/li><\/ul>\n\n\n\n<p><strong>Influenza&nbsp;prevention&nbsp;( local&nbsp;flu&nbsp;).<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults and children 5 years and older:<\/strong>&nbsp;The recommended&nbsp;dose&nbsp;is 2&nbsp;inhalations&nbsp;(2 blisters) once daily for up to 28 days.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Relenza than you should<\/h2>\n\n\n\n<p>If you accidentally take too high a&nbsp;dose&nbsp;of Relenza, this will probably not cause you any problems.&nbsp;<strong>However, you should contact your doctor<\/strong>&nbsp;if you are worried or unwell, especially if you have&nbsp;asthma&nbsp;or other lung problems.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0a child accidentally ingested the drug,<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Relenza<\/h2>\n\n\n\n<p>If you forget to take a\u00a0dose\u00a0of Relenza, take your usual\u00a0dose\u00a0as soon as possible.\u00a0Then continue to use your medicine as before.<br><strong>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Relenza<\/h2>\n\n\n\n<p><strong>When treating the\u00a0flu<\/strong>, you must complete the entire treatment\u00a0(normally 5 days) even if you feel better, otherwise, the flu symptoms may return.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Contact a doctor<\/strong>&nbsp;if you plan to stop treatment with Relenza prematurely.<\/li><\/ul>\n\n\n\n<p><strong>There is a step-by-step instruction at the back of this leaflet that shows you how to use\u00a0Diskhaler<\/strong>.\u00a0Read it carefully before taking your first\u00a0dose.\u00a0If you are still unsure about how to use\u00a0Diskhaler, ask someone at the pharmacy to review the instructions with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Conditions you need to be aware of:<\/strong><\/p>\n\n\n\n<p><strong>Severe allergic reactions<\/strong><\/p>\n\n\n\n<p>These are rare and occur in&nbsp;<strong>less than 1 in 1000<\/strong>&nbsp;users of Relenza.&nbsp;Signs of these include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Elevated and itchy rash (hives)<\/strong><\/li><li><strong>Swelling &#8211; sometimes of the face, mouth, or throat, which makes it difficult to breathe<\/strong><\/li><li><strong>Collapse.<\/strong><\/li><\/ul>\n\n\n\n<p>If you get any of these symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Contact a doctor immediately.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Severe skin reactions<\/strong><\/p>\n\n\n\n<p>These&nbsp;side effects&nbsp;are rare and may affect&nbsp;<strong>less than 1 in 1000<\/strong>&nbsp;people in Relenza:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Skin rashes, which can become blisters and look like small targets (dark spot in the middle surrounded by a lighter field and a dark ring along the edge &#8211; erythema multiforme), scattered skin rashes with blisters and flaking skin, occur especially around the mouth, nose, eyes and the genitals (&nbsp;Stevens-Johnson syndrome&nbsp;), extensive skin detachment on large parts of the body (&nbsp;toxic epidermal necrolysis&nbsp;).<\/li><li>If you notice any of these symptoms, contact your doctor immediately.&nbsp;Stop using Relenza.<\/li><\/ul>\n\n\n\n<p><strong>Other common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Occurs in&nbsp;<strong>less than 1 in 10<\/strong>&nbsp;users of Relenza:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rash<\/li><\/ul>\n\n\n\n<p><strong>Other less common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Occurs in less than 1 in&nbsp;<strong>100<\/strong>&nbsp;users of Relenza:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Feeling of tightness in the throat or pressure over the chest, shortness of breath,<\/strong> or sudden difficulty breathing.\u00a0If you have a lung disease (eg\u00a0asthma\u00a0or COPD) your treatment may need to be followed up while you are taking Relenza as you may experience this side effect.<\/li><li>Swelling of the face, mouth, or throat.<\/li><li>&#8220;Hives&#8221; (raised, itchy rash).<\/li><li><strong>Fainting and dizziness in the head.\u00a0<\/strong>If you do not feel well when you take Relenza, you may faint or feel dizzy after inhaling Relenza.\u00a0Before inhaling Relenza\u00a0dose\u00a0one, sit down in a relaxed position and only hold your breath for as long as it is comfortable after\u00a0dose\u00a0one has been inhaled.<\/li><\/ul>\n\n\n\n<p>If you feel unwell, you should have someone next to you when you inhale your&nbsp;dose of&nbsp;Relenza.<\/p>\n\n\n\n<p>If you get any of these symptoms, you should:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>stop using Relenza and seek medical help immediately.&nbsp;<\/strong>Contact a doctor or the nearest emergency department for advice.<\/li><\/ul>\n\n\n\n<p><strong>Sudden changes in behavior, hallucinations, and seizures<\/strong><\/p>\n\n\n\n<p>Behavioral changes such as confusion and incontestability have occurred during treatment with Relenza.\u00a0Some people may also have hallucinations (see, hear or experience things that do not exist) or seizures that can lead to unconsciousness.\u00a0Parents should pay special attention to these symptoms if their child or teen has the\u00a0flu.\u00a0These symptoms have been seen in people with\u00a0the flu\u00a0who have not used Relenza.\u00a0It is therefore not known whether Relenza had a role in causing these symptoms.<\/p>\n\n\n\n<p>If you get any of these symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Contact a doctor immediately.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Relenza<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Use Relenza and&nbsp;Diskhaler&nbsp;before the expiry date which is stated on the carton.<\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is zanamivir (5 mg per&nbsp;dose&nbsp;).<\/li><li>The other ingredients are&nbsp;lactose monohydrate&nbsp;(which contains milk protein).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Relenza\u00a0inhalation powder\u00a0is packaged in 4 blisters on a silver-colored\u00a0dose plate\u00a0of aluminum foil (Rotadisk).\u00a0The powder in each of these blisters contains 5 mg zanamivir.\u00a0The drug in the dosing discs is inhaled through the mouth using a plastic inhaler called\u00a0Diskhaler.<\/p>\n\n\n\n<p>Relenza is available in two different packages<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>starter&nbsp;pack for 1 day<\/strong>&nbsp;that contains 1&nbsp;dose plate&nbsp;Relenza Rotadisk and 1&nbsp;Diskhaler<\/li><li><strong>pack for 5 days treatment<\/strong>&nbsp;containing 5&nbsp;dose discs&nbsp;Relenza Rotadisk and 1&nbsp;Diskhaler<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>GlaxoSmithKline AB, Box 516, 169 29 Solna<\/p>\n\n\n\n<p>Tel: 08-638 93 00<\/p>\n\n\n\n<p>Email: info.produkt@gsk.com<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Glaxo Wellcome Production<\/p>\n\n\n\n<p>Industrial Zone No.2<\/p>\n\n\n\n<p>23 Rue Lavoisier<\/p>\n\n\n\n<p>27000 Evreux<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>GlaxoSmithKline Trading Services Limited<\/p>\n\n\n\n<p>12 Riverwalk<\/p>\n\n\n\n<p>Citywest Business Campus<\/p>\n\n\n\n<p>Dublin 24<\/p>\n\n\n\n<p>Ireland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Relenza contains zanamivir, which belongs to a group of medicines called antivirals . Relenza is used to treat flu ( flu virus infection ). It reduces flu symptoms and helps you recover faster.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22619,22614,22615,22618,22616,22617,22613,22612,6020,6022],"class_list":["post-21840","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-benefits-of-relenza","tag-benefits-of-zanamivir","tag-relenza","tag-relenza-side-effects","tag-what-is-relenza","tag-what-relenza-is-used-for","tag-what-zanamivir-is-used-for","tag-wht-is-zanamivir","tag-zanamivir","tag-zanamivir-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21840","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21840"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21840\/revisions"}],"predecessor-version":[{"id":21863,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21840\/revisions\/21863"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21840"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21840"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21840"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}