{"id":21659,"date":"2022-06-01T06:33:52","date_gmt":"2022-06-01T06:33:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21659"},"modified":"2022-06-01T09:58:42","modified_gmt":"2022-06-01T09:58:42","slug":"rasagiline-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/rasagiline-accord\/","title":{"rendered":"Rasagiline Accord &#8211; Rasagiline uses, dose and side effects"},"content":{"rendered":"\n<p>1 mg&nbsp;rasagiline&nbsp;tablets<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Rasagiline Accord is and what it is used for<\/h2>\n\n\n\n<p>Rasagiline Accord contains the active substance rasagiline and is used to treat&nbsp;Parkinson&#8217;s disease&nbsp;in adults.&nbsp;It can be used with or without&nbsp;levodopa&nbsp;(another medicine used to treat&nbsp;Parkinson&#8217;s disease&nbsp;).<\/p>\n\n\n\n<p>In\u00a0Parkinson&#8217;s disease, there is a lack of cells that produce\u00a0dopamine\u00a0in the brain.\u00a0Dopamine\u00a0is a substance in the brain involved in movement control.\u00a0Rasagiline Accord helps increase and maintain\u00a0dopamine\u00a0levels in the brain.<\/p>\n\n\n\n<p>Rasagiline contained in Rasagiline Accord may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Rasagiline Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Rasagiline Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to rasagiline or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have severe liver problems.<\/li><\/ul>\n\n\n\n<p>Do not take the&nbsp;following medicines while taking Rasagiline Accord:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>monoamine oxidase (MAO) inhibitors (for the treatment of depression or\u00a0Parkinson&#8217;s disease\u00a0or any other indication), including over-the-counter and herbal medicines, e.g.\u00a0St. John&#8217;s wort<\/li><li>pethidine (a powerful painkiller).<\/li><\/ul>\n\n\n\n<p>You must wait at least 14 days after stopping Rasagiline Accord treatment before starting treatment with an MAOI or pethidine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Talk to your doctor or pharmacist before taking Rasagiline Accord&nbsp;<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have liver problems.<\/li><li>You should talk to your doctor about any suspected skin changes.&nbsp;Treatment with Rasagiline Accord may increase the risk of skin cancer.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you or your family\/caregiver notice that you are developing unusual behavior where you can not resist impulses urges or temptations to engage in certain activities that may harm yourself or others.\u00a0This behavior is called impulse control disorder.\u00a0In patients taking Rasagiline Accord and\/or other medicines for\u00a0Parkinson&#8217;s disease, obsessive-compulsive behavior, obsessive-compulsive disorder, gambling addiction, excessive spending, impulsive behavior, and an abnormally high sex drive or an increase in sexual thoughts or feelings have been observed.\u00a0Your doctor may need to adjust your\u00a0dose\u00a0or stop treatment (see section 4).<\/p>\n\n\n\n<p>Rasagiline Accord can cause drowsiness and cause you to suddenly fall asleep in connection with everyday activities during the day.&nbsp;This is especially true if you are also taking other dopaminergic medicines (used to treat&nbsp;Parkinson&#8217;s disease&nbsp;).&nbsp;For further information, see the section Driving and using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>It is not relevant to use Rasagiline Accord in children and adolescents.&nbsp;Rasagiline Accord is therefore not recommended for use under 18 years of age.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Rasagiline Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>You must tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain antidepressant drugs (selective serotonin reuptake inhibitors, selective\u00a0serotonin\u00a0noradrenaline reuptake inhibitors, tricyclic or tetracyclic antidepressants)<\/li><li>the antibiotic\u00a0ciprofloxacin\u00a0against\u00a0infection\u00a0er<\/li><li>the antitussive drug dextromethorphan<\/li><li>sympathomimetics\u00a0of the type found in\u00a0eye drops, nasal decongestants, or cold medicines containing\u00a0ephedrine\u00a0or pseudoephedrine<\/li><\/ul>\n\n\n\n<p>The use of Rasagiline Accord in combination with antidepressants containing\u00a0fluoxetine\u00a0or fluvoxamine should be avoided.\u00a0If you start treatment with Rasagiline Accord, you should wait at least five weeks after stopping treatment with\u00a0fluoxetine.\u00a0If you start treatment with\u00a0fluoxetine\u00a0or fluvoxamine, you should wait at least 14 days after stopping Rasagiline Accord\u2011 treatment.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you smoke or plan to quit smoking.&nbsp;Smoking can reduce the amount of Rasagiline Accord in the blood.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>As it is not known how Rasagiline Accord affects pregnancy and the unborn baby, you should avoid taking Rasagiline Accord if you are pregnant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Consult a physician before driving or using machines, as both\u00a0Parkinson&#8217;s disease\u00a0itself and treatment with Rasagiline Accord may affect your ability to do so.\u00a0Rasagiline Accord may make you feel dizzy and drowsy.\u00a0It can also cause sudden sleep attacks.\u00a0This may be worse if you are taking other medicines to treat the symptoms of\u00a0Parkinson&#8217;s disease, if you are taking medicines that may cause drowsiness or if you drink alcohol while taking Rasagiline Accord.\u00a0If you have experienced drowsiness ( somnolence\u00a0) and\/or sudden sleep attacks before or in connection with taking Rasagiline Accord,\u00a0do not drive or use machines (see section 2).<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Rasagiline Accord contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie it is essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Rasagiline Accord<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;of Rasagiline Accord is 1 tablet of 1 mg daily, taken orally.&nbsp;Rasagiline Accord can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Rasagiline Accord than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine, contact a doctor or hospital by mistake for assessment of the risk and advice.\u00a0Bring the carton\/blister pack or jar of Rasagiline Accord to your doctor or pharmacist.<\/p>\n\n\n\n<p>Reported symptoms due to overdose of Rasagiline Accord include mild euphoric mood (a mild form of mania), extremely high\u00a0blood pressure,\u00a0and serotonergic syndrome (see section 4).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Rasagiline Accord<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.\u00a0Take the next\u00a0dose\u00a0as usual, when it&#8217;s time to take it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Rasagiline Accord<\/h2>\n\n\n\n<p>Do not stop taking Rasagiline Accord without first talking to a doctor.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately<\/strong>&nbsp;if you notice any of the following symptoms.&nbsp;You may need&nbsp;urgent&nbsp;medical advice or treatment:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you develop abnormal behavior such as obsessive-compulsive behavior, obsessive-compulsive disorder, gambling addiction, excessive shopping or spending, impulsive behavior, and abnormally high sex drive or increase in sexual thoughts (impulse control disorders) (see section 2)<\/li><li>if you see or hear things that do not exist (hallucinations)<\/li><li>if you experience hallucinations, fever, restlessness, tremors, and sweating in any combination (serotonergic syndrome).<\/li><\/ul>\n\n\n\n<p><strong>Contact your doctor<\/strong>&nbsp;if you notice any suspected skin change as there may be an increased risk of skin cancer (&nbsp;melanoma&nbsp;) when using this medicine (see section 2).<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;ar<\/p>\n\n\n\n<p>Very common&nbsp;<em>(may affect more than 1 user in 10)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>involuntary movements (&nbsp;dyskinesia&nbsp;)<\/li><li>headache.<\/li><\/ul>\n\n\n\n<p>Common&nbsp;<em>(may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>abdominal pain<\/li><li>case<\/li><li>allergy<\/li><li>fever<\/li><li>influenza<\/li><li>general malaise<\/li><li>account<\/li><li>chest pain (angina)<\/li><li>drop in blood pressure when getting up, with symptoms such as dizziness\/feeling of instability (\u00a0orthostatic\u00a0hypotension\u00a0)<\/li><li>decreased appetite<\/li><li>constipation<\/li><li>dry mouth<\/li><li>nausea and vomiting<\/li><li>flatulence\u00a0(gas formation)<\/li><li>abnormal results on blood tests (\u00a0leukopenia\u00a0)<\/li><li>joint pain (\u00a0arthralgia\u00a0)<\/li><li>muscle \/ skeletal pain<\/li><li>joint inflammation (\u00a0arthritis\u00a0)<\/li><li>numbness and weakening of the muscles in the hand (\u00a0carpal tunnel syndrome\u00a0)<\/li><li>reduced weight<\/li><li>dream disorders<\/li><li>difficulty coordinating muscles (balance disorder)<\/li><li>Depression<\/li><li>dizziness (fraud)<\/li><li>abnormal muscle tension (\u00a0dystonia\u00a0)<\/li><li>rinnsnuva (\u00a0rinit\u00a0)<\/li><li>irritated skin (\u00a0dermatitis\u00a0)<\/li><li>rash<\/li><li>eye inflammation (\u00a0conjunctivitis\u00a0)<\/li><li>urinary incontinence.<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;<em>(may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stroke (&nbsp;cerebrovascular&nbsp;event)<\/li><li>heart attack (heart attack)<\/li><li>skin rash with blisters (vesicular bullous rash).<\/li><\/ul>\n\n\n\n<p>Has been reported (&nbsp;<em>occurs&nbsp;<\/em><em>in an unknown number of users<\/em>&nbsp;)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high&nbsp;blood pressure<\/li><li>excessive drowsiness<\/li><li>sudden sleep attack.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Rasagiline Accord<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton, can or blister after EXP.&nbsp;dat \/ EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is rasagiline.\u00a0Each tablet contains 1 mg rasagiline (as rasagiline tartrate).<\/li><li>The other ingredients are microcrystalline cellulose, maize starch, pregelatinized maize starch, talc, and sodium stearyl fumarate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Rasagiline Accord tablets are white to off-white, round, flat tablets with a bevelled edge (6.5 mm).<\/p>\n\n\n\n<p>Pack sizes of 7, 10, 28, 30, 60, 100 or 112 tablets in blisters.<\/p>\n\n\n\n<p>Pack sizes of 30 tablets in a tablet jar with a child-resistant screw cap containing desiccant (silica gel).&nbsp;The desiccant should not be swallowed.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 VK Utrecht<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Deloris Pharmaceuticals Ltd<\/p>\n\n\n\n<p>17 Athinon Street, Ergates Industrial Area<\/p>\n\n\n\n<p>2643 Ergates Nicosia, Cyprus<\/p>\n\n\n\n<p>Iberfar &#8211; Ind\u00fastria Farma\u0109eutica, SA<\/p>\n\n\n\n<p>Rua Consiglieri Pedroso, no.&nbsp;121-123<\/p>\n\n\n\n<p>Queluz de Baixo, Barcarena 2745-557, Portugal<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rasagiline Accord contains the active substance rasagiline and is used to treat Parkinson&#8217;s disease in adults. It can be used with or without levodopa (another medicine used to treat Parkinson&#8217;s disease ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[9482,22350,22354,22353,22349,9484,9483,22351,22352,9485],"class_list":["post-21659","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-rasagiline","tag-rasagiline-accord","tag-rasagiline-accord-side-effects","tag-rasagiline-accord-tablet","tag-rasagiline-side-effects","tag-rasagiline-tablet","tag-what-is-rasagiline","tag-what-is-rasagiline-accord","tag-what-rasagiline-accord-is-used-for","tag-what-rasagiline-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21659"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21659\/revisions"}],"predecessor-version":[{"id":21681,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21659\/revisions\/21681"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21659"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21659"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}