{"id":21654,"date":"2022-06-01T06:29:33","date_gmt":"2022-06-01T06:29:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21654"},"modified":"2023-02-23T07:36:37","modified_gmt":"2023-02-23T07:36:37","slug":"rapiscan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/rapiscan\/","title":{"rendered":"Rapiscan &#8211; Regadenoson Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Rapiscan 400 micrograms&nbsp;Regadenoson Solution&nbsp;For Injection<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Is Rapiscan And What Rapiscan Used For?<\/h2>\n\n\n\n<p>Rapiscan contains the active substance\u00a0<strong><em>regadenoson<\/em><\/strong>.\u00a0It belongs to a group of medicines called\u00a0<em>&#8220;coronary vasodilators.&#8221;\u00a0<\/em>It causes the heart arteries to dilate and the heart rate to increase.\u00a0This causes more blood to flow to the muscles of the heart. <strong><span style=\"text-decoration: underline;\">Intended for diagnostics only.<\/span><\/strong><\/p>\n\n\n\n<p>Rapiscan regadenoson is used in cardiac examination in adults called\u00a0<strong><em>&#8220;myocardial perfusion imaging&#8221;<\/em><\/strong><em>.<\/em> A diagnostic drug is used to create images in this type of examination.<\/p>\n\n\n\n<p>These pictures show how well the blood flows to the heart&#8217;s muscles.\u00a0Physical exertion is usually used on a pedal machine to load the heart before the examination.\u00a0During physical exertion, a small amount of diagnostic drug is injected into the body, often into a vein in hand.<\/p>\n\n\n\n<p>Then pictures are taken of the heart.\u00a0When loaded, the doctor can see if the heart muscles get enough blood flow. If you cannot perform sufficient physical exertion to achieve the desired load on the heart, Rapiscan is injected to provide a load on the heart at the corresponding level and thus increase blood flow.<\/p>\n\n\n\n<p>Rapiscan is also used in catheterization and imaging of\u00a0arteries\u00a0in the heart (\u00a0invasive\u00a0coronary angiography) to dilate the heart vessels to measure the pressure differences caused by narrowing in one or more\u00a0vessels.<\/p>\n\n\n\n<p>During\u00a0cardiac catheterization, a long narrow tube called a\u00a0catheter\u00a0is inserted, either through your femoral artery (via the groin) or your radicular artery (via the forearm) and runs through your blood vessels to the heart.<\/p>\n\n\n\n<p>The catheterization doctor may also want to measure the pressure difference (fractional flow reserve) if constrictions are detected in one or more cardiovascular vessels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before You Get Rapiscan?<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Rapiscan:\u00a0<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have a\u00a0<strong>slow heart rate\u00a0<\/strong><em>(high heart rate or sinus node disease)<\/em>\u00a0and do not have a pacemaker.<\/li><li>If you have\u00a0chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a>\u00a0that occurs unpredictably (\u00a0unstable angina\u00a0) and has not improved after treatment.<\/li><li>If you have\u00a0low\u00a0blood pressure\u00a0(\u00a0hypotension\u00a0).<\/li><li>If you have\u00a0heart failure.<\/li><li>If you are allergic to regadenoson or any other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Talk To Your Doctor Or Pharmacist Before Taking Rapiscan<\/h2>\n\n\n\n<p>Before you receive Rapiscan, your doctor needs to know the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have\u00a0recently\u00a0had a\u00a0serious heart problem\u00a0(\u00a0such as a heart attack or abnormal heart rhythm\u00a0).<\/li><li>If you have a heart rhythm where your heartbeat is very fast or irregular (\u00a0atrial fibrillation\u00a0or\u00a0atrial flutter\u00a0).<\/li><li>If you have high\u00a0blood pressure\u00a0that is not controlled, especially if problems with nosebleeds, headaches or blurred vision, or <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/distinction-and-double-vision-in-adults\/\">double vision<\/a> have recently accompanied this.<\/li><li>If you have had problems with &#8220;mini&#8221; strokes (so-called\u00a0TIA,\u00a0transient ischemic attacks\u00a0).<\/li><li>If you have a heart rhythm disorder called\u00a0long\u00a0QT\u00a0syndrome.<\/li><li>If you have episodes of\u00a0heart block\u00a0(which may lower your heart rate) or a very slow heart rate.<\/li><li>If you have a\u00a0cardiovascular\u00a0condition that\u00a0worsens\u00a0when your\u00a0blood pressure\u00a0drops.<\/li><li>These include low blood volume (\u00a0for example, caused by severe diarrhea or dehydration or\u00a0diuretic\u00a0tablets\u00a0),\u00a0inflammation\u00a0around the heart (\u00a0pericarditis\u00a0), and certain forms of a heart valve or artery disease (\u00a0for example,\u00a0aortic\u00a0or\u00a0mitral stenosis\u00a0).<\/li><li>If you have a condition that causes seizures, such as\u00a0epilepsy, or if you have ever had seizures.<\/li><li>If you have\u00a0asthma\u00a0or\u00a0lung disease.<\/li><\/ul>\n\n\n\n<p>If any of these apply to you,&nbsp;<strong>tell your doctor before getting&nbsp;an&nbsp;injection<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People:<\/h2>\n\n\n\n<p>This medicine should not be used in children and adolescents under 18.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Rapiscan:<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p><strong>Take special care with the following medicines:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Theophylline<\/strong>, a medicine used to treat\u00a0asthma\u00a0and other lung diseases,\u00a0should not be used for at least 12 hours before\u00a0receiving Rapiscan, as it may block the effect of Rapiscan.<\/li><li>Dipyridamole, a medicine used to prevent blood clots,\u00a0<strong>should not be used for at least two days before<\/strong>\u00a0receiving Rapiscan, as it may alter the effect of Rapiscan.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Rapiscan With Food, Drink, And Alcohol:<\/h2>\n\n\n\n<p>Do not eat beverages containing caffeine (e.g., tea, coffee, cocoa, Coca-Cola, or chocolate) for at least 12 hours before receiving Rapiscan.\u00a0This is because caffeine can interfere with the effects of Rapiscan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding:<\/h2>\n\n\n\n<p>Before you take Rapiscan, tell your doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If<strong>\u00a0<\/strong>you are pregnant,\u00a0think you may be pregnant or planning to have a baby.\u00a0There is insufficient information on the use of Rapiscan in pregnant women.\u00a0Harmful effects have been seen in animal studies, but it is unknown if there is a risk to humans.\u00a0Your doctor will only give you Rapiscan if necessary.<\/li><li>If\u00a0you are breastfeeding, it is unknown if Rapiscan is excreted in human milk, and you will only get it if your doctor thinks it is necessary.\u00a0You should avoid breastfeeding for at least 10 hours after receiving this medicine. Ask your doctor for advice before taking any medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines:<\/h2>\n\n\n\n<p>Rapiscan can make you feel dizzy.\u00a0It may cause other symptoms (headache or shortness of breath), affecting your ability to drive or use machines.\u00a0These effects last no longer than 30 minutes.\u00a0Do not drive or use any tools or machines until these symptoms have improved.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Rapiscan Contains Sodium:<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose.&nbsp;After receiving Rapiscan, you will receive an&nbsp;injection&nbsp;of sodium chloride 9 mg\/ml (0.9%) solution containing 45 mg of&nbsp;sodium.&nbsp;This should be considered if you have been prescribed a low-salt diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Is Rapiscan given?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Rapiscan is injected by a healthcare professional<\/strong>\u00a0(a doctor, nurse, or biomedical analyst) into a medical device where your heart and\u00a0blood pressure\u00a0can be monitored.\u00a0It is injected directly into a vein in a single\u00a0dose\u00a0of 400 micrograms in 5 ml solution &#8211;\u00a0injection\u00a0one takes about 10 seconds to complete.\u00a0The injected\u00a0dose\u00a0does not depend on your weight.<\/li><li><strong>You will also receive<\/strong>\u00a0an\u00a0injection\u00a0of sodium chloride 9 mg\/ml (0.9%) solution (5 ml) and a small amount of diagnostic medicine.<\/li><li><strong>When you receive Rapiscan<\/strong>, your heart rate will increase rapidly.\u00a0Your heart rate and\u00a0blood pressure\u00a0will be monitored.<\/li><li><strong>After\u00a0injecting\u00a0Rapiscan<\/strong>, you must sit or lie down until your heart rate and\u00a0blood pressure\u00a0return to normal.\u00a0Your doctor, nurse, or biomedical analyst will tell you when you can get up.<\/li><li>The examination of your heart is done when sufficient time has passed so that the diagnostic medicine has had time to reach the heart muscle.<\/li><li>During catheterization of the\u00a0vessels\u00a0of the heart, your doctor can measure the pressure difference that occurs due to a narrowing of one or more\u00a0vessels.\u00a0This pressure difference is called the fractional flow reserve &#8211; FFR.<\/li><li>If necessary, the second\u00a0dose\u00a0of 400 micrograms may be injected at least 10 minutes after the first\u00a0dose\u00a0to measure the pressure difference during the same catheterization procedure.\u00a0Heart rate and\u00a0blood pressure\u00a0are monitored throughout the procedure.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Rapiscan Than You Should:<\/h2>\n\n\n\n<p>Some people have developed\u00a0redness, dizziness, and increased heart rate when they receive too much Rapiscan.\u00a0If your doctor thinks you have serious\u00a0side effects\u00a0or the effects of Rapiscan last too long, you may be given an\u00a0injection\u00a0of a drug called aminophylline that reduces these effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Rapiscan Side Effects:<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them. <strong>The side effects\u00a0are usually mild.\u00a0<\/strong>They usually start shortly after\u00a0injection\u00a0of Rapiscan and are<strong>\u00a0usually over within 30 minutes<\/strong>.\u00a0They usually do not need any treatment.<\/p>\n\n\n\n<p><strong>More serious&nbsp;side effects&nbsp;include:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden cardiac arrest or damage to the heart, heart block (a disturbance of the heart&#8217;s electrical signal so that the signal can not be transmitted from the atrium to the ventricle), rapid heartbeat<\/li><li>low\u00a0blood pressure, which may result in fainting or minor strokes (including facial weakness or inability to speak).\u00a0In rare cases, Rapiscan may cause a\u00a0stroke\u00a0(also known as a sudden\u00a0cerebrovascular\u00a0disorder)<\/li><li>An\u00a0allergic reaction\u00a0that may cause rash, streaks, swelling under the skin near the eyes or throat, feeling of tightness in the throat, and difficulty breathing that may occur immediately or be delayed after\u00a0injection\u00a0of Rapiscan<\/li><\/ul>\n\n\n\n<p>Tell your doctor immediately if you think you have serious&nbsp;side effects.&nbsp;Your doctor may give you an&nbsp;injection&nbsp;of a medicine called aminophylline that reduces these effects.<\/p>\n\n\n\n<p><strong>Very common:\u00a0<em>(may affect more than 1 user in 10)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Dizziness<\/li><li>Shortness of breath<\/li><li>Chest pain<\/li><li>Altered results in cardiac examinations (\u00a0electrocardiogram\u00a0)<\/li><li>Redness<\/li><li>Discomfort in the stomach<\/li><\/ul>\n\n\n\n<p><strong>Usual:\u00a0<\/strong><em><strong>(may affect up to 1 in 10 users)<\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart pain (angina)<\/li><li>Abnormal heart rhythm<\/li><li>Fast heartbeat<\/li><li>Feeling of the heart skipping a beat<\/li><li>Fluttering or beating too hard or too fast (palpitations)<\/li><li>Low\u00a0blood pressure<\/li><li>Congested throat<\/li><li>Throat irritation<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">Cough<\/a><\/li><li>Vomiting<\/li><li>Nausea<\/li><li>Feeling sick or feeling weak<\/li><li>Heavy sweating<\/li><li>Pain in the back, arms, legs, neck, or jaw<\/li><li>Discomfort in the skeleton and muscles<\/li><li>Tingling<\/li><li>Decreased sensation<\/li><li>Taste changes<\/li><li>Discomfort in the mouth<\/li><\/ul>\n\n\n\n<p><strong>Uncommon:\u00a0<em>(may affect up to 1 in 100 users)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden cardiac arrest or damage to the heart, heart block (a disturbance of the heart&#8217;s electrical signal so that the signal can not be transmitted from the atrium to the ventricle)<\/li><li>Slow heartbeat<\/li><li>Seizures<\/li><li>Fainting<\/li><li>Minor strokes (including facial weakness or inability to speak)<\/li><li>Decreased level of consciousness (which may include unconsciousness)<\/li><li>Tremors<\/li><li>Drowsiness<\/li><li>An\u00a0allergic reaction\u00a0that can cause rash, streaks, swelling under the skin near the eyes or throat, feeling of tightness in the throat, difficulty breathing<\/li><li>Hissing breathing<\/li><li>Rapid breathing<\/li><li>High\u00a0blood pressure, pallor<\/li><li>Cold\u00a0extremity\u00a0er<\/li><li>Blurred vision<\/li><li>Eye pain<\/li><li>Anxiety<\/li><li>Difficulty sleeping<\/li><li>Ringing in the ears<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/flatulence\/\">Flatulence<\/a>, diarrhea, involuntary discharge of feces<\/li><li>Reddening of the skin<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a><\/li><li>Pain or discomfort around the injected area<\/li><li>Body pain<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>  <em>(frequency can not be calculated from available data)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Breathing difficulties (bronchial spasm)<\/li><li>Respiratory arrest<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Rapiscan?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the vial and carton after EXP.\u00a0No special storage instructions.<\/li><li>Rapiscan must not be used if the solution is discolored or contains particles.<\/li><li>Medicines should not be disposed of via wastewater or household waste.\u00a0These measures will help to protect the environment.\u00a0Healthcare professionals will be responsible for the storage and destruction of this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Pack And Other Information:<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance in Rapiscan is regadenoson.&nbsp;Each 5 ml Rapiscan&nbsp;vial&nbsp;contains 400 micrograms of regadenoson.<\/li><li>The other ingredients are disodium edetate, disodium phosphate dihydrate, sodium dihydrogen phosphate monohydrate, propylene glycol, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack?<\/h2>\n\n\n\n<p>Rapiscan&nbsp;solution for injection&nbsp;is a clear, colorless solution with no visible particles.&nbsp;Rapiscan is delivered in a carton containing a 5 ml disposable vial with a rubber stopper and an aluminum sealed lid.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorisation Holder:<\/p>\n\n\n\n<p>GE Healthcare AS<\/p>\n\n\n\n<p>Nycoveien 1<\/p>\n\n\n\n<p>NO-0485 Oslo<\/p>\n\n\n\n<p>Norway<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>Millimount Healthcare Limited,<\/p>\n\n\n\n<p>Block 7, City North Business Campus,<\/p>\n\n\n\n<p>Stamullen, Co Meath, K32 YD60 Ireland<\/p>\n\n\n\n<p>Haupt Pharma Wolfratshausen GmbH<\/p>\n\n\n\n<p>Pfaffenrieder Str. 5<\/p>\n\n\n\n<p>D-82515 Wolfratshausen<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rapiscan is only for diagnostic purposes. It is used in a form of heart scan called &#8216;radionuclide myocardial perfusion imaging&#8217; to see how much blood is flowing through the heart muscle.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[22363,22364,22371,22365],"class_list":["post-21654","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-regadenoson","tag-what-is-regadenoson","tag-what-rapiscan-is-used-for","tag-what-regadenoson-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21654"}],"version-history":[{"count":60,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21654\/revisions"}],"predecessor-version":[{"id":51208,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21654\/revisions\/51208"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21654"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}