{"id":21592,"date":"2022-05-30T06:17:32","date_gmt":"2022-05-30T06:17:32","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21592"},"modified":"2022-05-30T10:40:18","modified_gmt":"2022-05-30T10:40:18","slug":"ramipril-hydrochlorothiazide-hexal","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ramipril-hydrochlorothiazide-hexal\/","title":{"rendered":"Ramipril \/ Hydrochlorothiazide HEXAL &#8211; Ramipril and hydrochlorothiazide uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg \/ 12.5 mg, 5 mg \/ 25 mg&nbsp;tablets<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triatec\/\">ramipril<\/a> and&nbsp;hydrochlorothiazide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Ramipril \/ Hydrochlorothiazide HEXAL is and what it is used for<\/h2>\n\n\n\n<p>Ramipril \/ Hydrochlorothiazide HEXAL is a combination of two medicines called ramipril and&nbsp;hydrochlorothiazide&nbsp;.<\/p>\n\n\n\n<p><strong>Ramipril<\/strong>&nbsp;belongs to a group of medicines called &#8216;ACE inhibitors&#8217; (&nbsp;Angiotensin&nbsp;Converting&nbsp;Enzyme&nbsp;inhibitors) that work by:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reduce the body&#8217;s production of substances that increase your&nbsp;blood pressure<\/li><li>Make your blood vessels dilate and relax<\/li><li>Make it easier for your heart to pump blood around your body<\/li><\/ul>\n\n\n\n<p><strong>Hydrochlorothiazide<\/strong>\u00a0belongs to a group of medicines called &#8220;thiazide diuretics&#8221; or diuretics that work by increasing the amount of water (urine) produced in the body.\u00a0This lowers your\u00a0blood pressure.<\/p>\n\n\n\n<p>Ramipril \/ Hydrochlorothiazide HEXAL is used for high\u00a0blood pressure\u00a0.\u00a0The two active substances work together to lower your\u00a0blood pressure.\u00a0They are used together when one or the other has not worked alone.<\/p>\n\n\n\n<p>Ramipril\/hydrochlorothiazide contained in Ramipril \/ Hydrochlorothiazide HEXAL may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ramipril,\u00a0hydrochlorothiazide,\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to medicines similar to Ramipril \/ Hydrochlorothiazide HEXAL (other\u00a0ACE inhibitors\u00a0or\u00a0sulfonamides\u00a0). Signs of an\u00a0allergic reaction\u00a0may include rash, difficulty swallowing or breathing, and swelling of your face, lips, throat, or tongue.<\/li><li>if you have ever had a severe\u00a0allergic reaction\u00a0called &#8220;angioedema&#8221;.\u00a0Signs of this include\u00a0itching,\u00a0hives\u00a0(\u00a0urticaria\u00a0), red marks on the hands, feet, and neck, swelling of the throat and tongue, swelling around the eyes and lips, and difficulty breathing and swallowing.<\/li><li>if you are undergoing\u00a0dialysis\u00a0or any other type of blood filtration.\u00a0Depending on the machine used, Ramipril \/ Hydrochlorothiazide HEXAL may not be suitable for you.<\/li><li>if you have severe liver problems.<\/li><li>if you have abnormal amounts of salts (\u00a0calcium,\u00a0potassium,\u00a0sodium\u00a0) in your blood.<\/li><li>if you have kidney problems it means that the blood supply to your kidneys is reduced (\u00a0stenosis\u00a0of the renal artery).<\/li><li>if you have severe kidney problems and do not undergo\u00a0dialysis.<\/li><li>if you have\u00a0diabetes\u00a0or renal impairment and are being treated with a blood pressure-lowering medicine containing aliskiren.<\/li><li>if you have taken or are taking sacubitril\/valsartan, a medicine used to treat a type of long-term (\u00a0chronic\u00a0)\u00a0heart failure\u00a0in adults, it increases the risk of\u00a0angioedema\u00a0(rapid swelling under the skin in an area such as the throat).<\/li><li>during the last 6 months of pregnancy (see section \u201cPregnancy and breastfeeding\u201d below).<\/li><li>if you are breastfeeding (see section \u201cPregnancy and breastfeeding\u201d below).<\/li><\/ul>\n\n\n\n<p>Do not take Ramipril \/ Hydrochlorothiazide HEXAL if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor before taking Ramipril \/ Hydrochlorothiazide HEXAL.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Ramipril \/ Hydrochlorothiazide HEXAL:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have heart, liver, or kidney problems<\/li><li>if you have lost a lot of body salts or body fluids (through vomiting, diarrhea, abnormal sweating, strictly low-salt diet, treatment with\u00a0diuretics\u00a0for a long time, or have undergone\u00a0dialysis\u00a0)<\/li><li>if you are going to undergo a treatment to reduce your\u00a0allergy\u00a0to wasp or bee stings (\u00a0hyposensitization\u00a0)<\/li><li>if you will be given anesthetics or anesthetics.\u00a0This can be given to you before an operation or dental treatment.\u00a0You may need to stop taking Ramipril \/ Hydrochlorothiazide HEXAL one day before surgery;\u00a0Ask your doctor for advice<\/li><li>if you suffer from primary aldosteronism (extra fluid in your body caused by too much of a\u00a0hormone\u00a0called\u00a0aldosterone\u00a0)<\/li><li>if you have high levels of\u00a0potassium\u00a0in your blood (shown by a blood test)<\/li><li>if you are taking medicines or have a condition that can reduce the sodium levels (salinity) in your blood. Your doctor may take regular blood tests to check your blood\u00a0sodium\u00a0levels, especially if you are older (see section 4).<\/li><li>the risk of\u00a0angioedema\u00a0may increase if you take any of the following medicines:<ul><li>racecadotril, a medicine used to treat diarrhea<\/li><li>drugs used to prevent rejection of transplanted organs and against cancer, called mTOR inhibitors (eg <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/torisel\/\">temsirolimus<\/a>, sirolimus, everolimus)<\/li><li>vildagliptin, a medicine used to treat\u00a0diabetes<\/li><\/ul><\/li><li>if you have a connective tissue disease such as scleroderma or\u00a0SLE\u00a0(systemic lupus erythematosus)<\/li><li>if you have had skin cancer or if you get an unforeseen skin change during treatment.\u00a0Treatment with hydrochlorothiazide, especially long-term use with high\u00a0doses, may increase the risk of certain types of skin and lip cancer (non-melanoma\u00a0skin cancer).\u00a0Protect your skin from exposure to sunlight and UV rays while taking Ramipril \/ Hydrochlorothiazide HEXAL<\/li><li>if you are taking any of the following medicines used to treat high blood pressure:<ul><li>an\u00a0angiotensin\u00a0II receptor blocker (ARB) (also known as sartans &#8211; for example, valsartan, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tolura\/\">telmisartan<\/a>, irbesartan), especially if you have diabetes-related kidney problems<\/li><li>aliskiren your doctor may need to check your kidney function,\u00a0blood pressure,\u00a0and the number of\u00a0electrolytes\u00a0(eg\u00a0potassium\u00a0) in your blood at regular intervals. See also the information under the heading \u201cDo not take Ramipril \/ Hydrochlorothiazide HEXAL\u201d.<\/li><\/ul><\/li><li>if you experience impaired vision or eye pain.\u00a0This may be a symptom of fluid accumulation in the eye (between the choroid and retina) or an increase in pressure in the eye and may occur within a few hours to weeks after taking Ramipril \/ Hydrochlorothiazide HEXAL.\u00a0Untreated, it can lead to permanent visual impairment.\u00a0If you have previously had a\u00a0penicillin\u00a0and sulfonamide allergy, you may be at a higher risk for this.\u00a0End treatment and consult a doctor (see section 4).<\/li><\/ul>\n\n\n\n<p>If you think you may be pregnant (or may become) pregnant during treatment, consult your doctor.&nbsp;Ramipril \/ Hydrochlorothiazide HEXAL is not recommended during the first 3 months of pregnancy and may cause birth defects if used later in pregnancy (see section \u201cPregnancy and breast-feeding\u201d below).<\/p>\n\n\n\n<p><strong>Ethnic differences<\/strong><\/p>\n\n\n\n<p>If you are a black patient of African descent, this medicine may be less effective in lowering your&nbsp;blood pressure&nbsp;or you may have a higher risk of&nbsp;angioedema&nbsp;(rapid swelling under the skin in an area such as the throat).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Ramipril \/ Hydrochlorothiazide HEXAL is not recommended for use in children and adolescents below 18 years.&nbsp;This is because the drug has never been used in this age group.<\/p>\n\n\n\n<p>If any of the above apply to you (or you are not sure), talk to your doctor before taking Ramipril \/ Hydrochlorothiazide HEXAL.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This is because Ramipril \/ Hydrochlorothiazide HEXAL may affect the way some other medicines work.\u00a0Some medicines may also affect the way Ramipril \/ Hydrochlorothiazide HEXAL works.<\/p>\n\n\n\n<p><em>Tell your doctor if you are taking any of the following medicines.&nbsp;They can make Ramipril \/ Hydrochlorothiazide HEXAL work worse:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drugs used to relieve pain and\u00a0inflammation\u00a0(non-steroidal anti-inflammatory drugs such as\u00a0ibuprofen\u00a0or indomethacin and\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>\u00a0)<\/li><li>Medicines are used to treat low\u00a0blood pressure,\u00a0shock,\u00a0heart failure,\u00a0asthma,\u00a0or\u00a0allergies\u00a0such as\u00a0ephedrine,\u00a0norepinephrine,\u00a0or\u00a0adrenaline.\u00a0Your doctor will check your\u00a0blood pressure.<\/li><\/ul>\n\n\n\n<p><em>Tell your doctor if you are taking any of the following medicines.&nbsp;They may increase the risk of&nbsp;side effects&nbsp;if you take them with Ramipril \/ Hydrochlorothiazide HEXAL:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drugs used to relieve pain and\u00a0inflammation\u00a0(non-steroidal anti-inflammatory drugs such as\u00a0ibuprofen\u00a0or indomethacin and\u00a0acetylsalicylic acid\u00a0)<\/li><li>Drugs that can reduce the amount of\u00a0potassium\u00a0in your blood.\u00a0These include medicines for constipation,\u00a0diuretics\u00a0(diuretics), amphotericin B (used to treat fungal infections), and ACTH (used to examine the function of your adrenal glands)<\/li><li>Anti-cancer drugs (\u00a0chemotherapy\u00a0)<\/li><li>Temsirolimus (for cancer)<\/li><li>Sirolimus, everolimus (for graft rejection\u00a0prevention\u00a0)<\/li><li>Medicines for heart problems including problems with heart rhythm<\/li><li>Diuretics\u00a0(diuretics) such as\u00a0furosemide<\/li><li>Potassium supplements (including salt substitutes), potassium-sparing\u00a0diuretics\u00a0(diuretics), and other medicines that may increase the amount of\u00a0potassium\u00a0in your blood (eg\u00a0spironolactone, triamterene, amiloride, trimethoprim, and cotrimoxazole against bacterial\u00a0infections; cyclosporine or tacrolimus, an immunosuppressive drug that prevents rejection of transplanted organs; and\u00a0heparin, a drug used to thin the blood to prevent blood clots).<\/li><li>Steroids\u00a0used in\u00a0inflammation\u00a0such as\u00a0prednisolone<\/li><li>Calcium supplementation<\/li><li>Allopurinol (used to reduce the amount of\u00a0uric acid\u00a0in your blood)<\/li><li>Procainamide\u00a0(used for heart rhythm disorders)<\/li><li>Cholestyramine (used to reduce blood fats)<\/li><li>Carbamazepine (used to\u00a0treat epilepsy\u00a0)<\/li><li>Vildagliptin (used to treat type 2\u00a0diabetes\u00a0)<\/li><li>NEP inhibitors (eg racecadotril used for diarrhea).<\/li><\/ul>\n\n\n\n<p>Your doctor may need to change your\u00a0dose\u00a0and\/or take other precautions:<\/p>\n\n\n\n<p>If you are taking an&nbsp;angiotensin&nbsp;II receptor blocker (ARB) or aliskiren (see also the information under the headings \u201cDo not take Ramipril \/ Hydrochlorothiazide HEXAL\u201d and \u201cWarnings and precautions\u201d).<\/p>\n\n\n\n<p><em>Tell your doctor if you are taking any of the following medicines.&nbsp;They may be affected by Ramipril \/ Hydrochlorothiazide HEXAL:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Antidiabetic\u00a0drugs\u00a0such as oral glucose-lowering drugs and\u00a0insulin.\u00a0Ramipril \/ Hydrochlorothiazide HEXAL may lower your blood sugar levels.\u00a0Check your blood sugar levels carefully while you are taking Ramipril \/ Hydrochlorothiazide HEXAL.<\/li><li>Lithium (used in mental illness).\u00a0Ramipril \/ Hydrochlorothiazide HEXAL may increase the amount of lithium in your blood.\u00a0Your lithium levels will need to be monitored closely by your doctor.<\/li><li>Muscle relaxants<\/li><li>Quinine (used against\u00a0malaria\u00a0)<\/li><li>Drugs that contain iodine, can be used in X-ray examinations in hospitals<\/li><li>Penicillin\u00a0(used to\u00a0treat infections\u00a0)<\/li><li>Oral blood thinners (oral\u00a0anticoagulants\u00a0) such as\u00a0warfarin.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you (or you are not sure), talk to your doctor before taking Ramipril \/ Hydrochlorothiazide HEXAL.<\/p>\n\n\n\n<p><strong>Surveys<\/strong><\/p>\n\n\n\n<p>Check with your doctor or pharmacist before taking your medicine:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Whether the function of your&nbsp;parathyroid gland&nbsp;should be examined.&nbsp;Ramipril \/ Hydrochlorothiazide HEXAL may affect the results of the study.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ramipril \/ Hydrochlorothiazide HEXAL with alcohol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you drink alcohol while taking Ramipril \/ Hydrochlorothiazide HEXAL you may feel dizzy.&nbsp;If you are concerned about how much you can drink while taking Ramipril \/ Hydrochlorothiazide HEXAL, talk to your doctor as alcohol may increase the effect of antihypertensive drugs.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>You must tell your doctor if you think you are (or might become) pregnant.<\/p>\n\n\n\n<p>You should not take Ramipril \/ Hydrochlorothiazide HEXAL during the first 12 weeks of pregnancy and you should not take them at all after the 13th week of pregnancy as use during pregnancy may be harmful to your baby.<\/p>\n\n\n\n<p>If you become pregnant while taking Ramipril \/ Hydrochlorothiazide HEXAL, tell your doctor immediately.&nbsp;A change to an alternative treatment that is better suited for pregnancy should be done in advance if you plan to become pregnant.<\/p>\n\n\n\n<p>You should not take Ramipril \/ Hydrochlorothiazide HEXAL if you are breastfeeding.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy when taking Ramipril \/ Hydrochlorothiazide HEXAL.\u00a0This is more likely to happen when you start taking Ramipril \/ Hydrochlorothiazide HEXAL or if you start taking a higher\u00a0dose.\u00a0If this happens, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ramipril \/ Hydrochloride HEXAL contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>To be swallowed.&nbsp;Taken at the same time each day, usually in the morning<\/li><li>This medicine can be taken with or without food<\/li><li>Swallow the tablets with liquid<\/li><li>Do not crush or chew the tablets.<\/li><\/ul>\n\n\n\n<p><strong>Recommended&nbsp;dose<\/strong><\/p>\n\n\n\n<p>Your doctor will adjust&nbsp;dose&nbsp;one until your&nbsp;blood pressure&nbsp;is under control.<\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>Your doctor will reduce the starting dose and adjust your treatment at a slower pace.<\/p>\n\n\n\n<p>Ramipril \/ Hydrochlorothiazide HEXAL 2.5 mg \/ 12.5 mg:<\/p>\n\n\n\n<p>The breaker is not there to divide the tablet into equal\u00a0doses, but only to facilitate swallowing.<\/p>\n\n\n\n<p>Ramipril \/ Hydrochlorothiazide HEXAL 5 mg \/ 25 mg:<\/p>\n\n\n\n<p>The tablet can be divided into two equal&nbsp;doses&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Ramipril \/ Hydrochlorothiazide HEXAL than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>Tell your doctor or see the emergency department at the nearest hospital as soon as possible.&nbsp;Do not drive to the hospital, ask someone else to drive you or call an ambulance.&nbsp;Bring your medicine pack.&nbsp;This is so that the doctor knows what you have taken.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a\u00a0dose, take your normal\u00a0dose\u00a0at the next dose<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a forgotten tablet.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop taking Ramipril \/ Hydrochlorothiazide HEXAL and see a doctor&nbsp;<\/strong><strong>immediately&nbsp;<\/strong><strong>if you notice any of the following serious&nbsp;side effects&nbsp;&#8211; you may need&nbsp;urgent&nbsp;medical attention:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, lips, or throat, which makes it difficult to swallow or breathe, as well as\u00a0itching\u00a0and rash.\u00a0This may be a sign of a severe\u00a0allergic reaction\u00a0to Ramipril \/ Hydrochlorothiazide HEXAL.<\/li><li>Severe skin reactions include rash, cold sores, worsening of skin conditions,\u00a0redness, blisters, or skin detachment (such as\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis,\u00a0or erythema multiforme).<\/li><li>Concentrated urine (dark color), nausea or vomiting, muscle cramps, confusion, and seizures may be caused by incorrect secretion of\u00a0ADH\u00a0(\u00a0antidiuretic hormone\u00a0) (see \u201cWarnings and Precautions\u201d).<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;have been reported (occurring in an unknown number of users).<\/p>\n\n\n\n<p><strong>Tell your doctor immediately if you experience:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased heart rate, irregular or severe heartbeat (\u00a0palpitations\u00a0), chest pain, pressure over the chest (less common\u00a0side effects\u00a0), or more serious problems including heart attack and\u00a0stroke\u00a0(\u00a0side effects\u00a0that occur in an unknown number of users).<\/li><li>Shortness of breath, cough, and fever for 2-3 days, and decreased appetite.\u00a0This may be a sign of lung problems including\u00a0pneumonia\u00a0(\u00a0side effects\u00a0that occur in an unknown number of users).<\/li><li>Bruising that occurs more easily than usual, prolonged bleeding time, signs of bleeding (eg bleeding in the gums), purple spots on the skin or increased susceptibility to infection, sore throat and fever, fatigue, weakness, dizziness, or pale skin.\u00a0This may be a sign of blood or bone marrow problems (\u00a0side effects\u00a0that occur in an unknown number of users).<\/li><li>Severe abdominal pain can be felt in the back.\u00a0This may be a sign of\u00a0pancreatitis\u00a0(\u00a0inflammation\u00a0of the pancreas) ( a\u00a0side effect\u00a0that occurs in an unknown number of users).<\/li><li>Fever, chills, fatigue, loss of appetite, abdominal pain, nausea, yellowing of the skin or eyes (jaundice).\u00a0This can be a sign of liver problems such as\u00a0hepatitis\u00a0(\u00a0inflammation\u00a0of the liver) (less common\u00a0side effect\u00a0) or other liver damage (a\u00a0side effect\u00a0that occurs in an unknown number of users).<\/li><li>Sudden myopia (side effect with unknown frequency).<\/li><li>Impaired vision or pain in the eyes, blurred vision or vision of halos around light sources, headache, watery eyes or nausea and vomiting due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or\u00a0acute\u00a0narrow-angle glaucoma\u00a0) (side effect with unknown frequency).\u00a0See &#8220;Warnings and Cautions&#8221;.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;include:<\/strong><\/p>\n\n\n\n<p>Tell your doctor if any of the following become serious or persist for more than a few days.<\/p>\n\n\n\n<p><strong>Common&nbsp;<\/strong><strong>(may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, fatigue, or feeling of weakness<\/li><li>Dizziness.\u00a0This is more likely to happen when you start taking Ramipril \/ Hydrochlorothiazide HEXAL or if you start taking a higher\u00a0dose.<\/li><li>Dry cough or\u00a0bronchitis<\/li><li>Blood tests show higher blood sugar than normal.\u00a0If you have\u00a0diabetes, this can make your\u00a0diabetes\u00a0worse.<\/li><li>Blood tests that show more\u00a0uric acid\u00a0or more fatty acids than normal<\/li><li>Sore, red, and swollen joints.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;<\/strong><strong>(may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Skin rash with or without swelling<\/li><li>Hemorrhoids, fainting, abnormally low\u00a0blood pressure\u00a0(\u00a0hypotension\u00a0), especially when standing or sitting up quickly<\/li><li>Balance problem (fraud)<\/li><li>Itching\u00a0and abnormal sensations in the skin such as numbness, tingling, tingling, burning sensation, or ant crawling (\u00a0paresthesia\u00a0)<\/li><li>Changed or lost taste experience<\/li><li>Sleep disorders<\/li><li>Depression, anxiety, increased nervousness or shaking<\/li><li>Nasal congestion, sinusitis, shortness of breath<\/li><li>Inflammation\u00a0of the gums (\u00a0gingivitis\u00a0), swelling of the mouth<\/li><li>Red, itchy, swollen, or watery eyes<\/li><li>Earrings<\/li><li>Dimsyn<\/li><li>Hair loss<\/li><li>Chest pain<\/li><li>Muscle pain<\/li><li>Constipation, stomach or intestinal pain<\/li><li>Poor digestion or nausea<\/li><li>Increased urination<\/li><li>Increased sweating or thirst<\/li><li>Lost or decreased appetite (\u00a0anorexia\u00a0), feeling of decreased hunger<\/li><li>Increased or irregular heartbeat<\/li><li>Swollen arms and legs.\u00a0This may be a sign that your body is storing more water than usual.<\/li><li>Fever<\/li><li>Sexual inability in men<\/li><li>Blood tests that show changes in the number of\u00a0red blood cells,\u00a0white blood cells,\u00a0or\u00a0platelets\u00a0or a decrease in the level of\u00a0hemoglobin<\/li><li>Blood tests that show changes in your liver function, pancreas, or kidney function<\/li><li>Blood tests show less\u00a0potassium\u00a0in your blood.<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;<\/strong><strong>(may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting, diarrhea, or heartburn<\/li><li>Red and swollen tongue or\u00a0dry mouth<\/li><li>Blood tests that show an increased amount of\u00a0potassium\u00a0than normal in your blood.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users):<\/strong><\/p>\n\n\n\n<p>Tell your doctor if any of the following become serious or persist for more than a few days<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty concentrating, restlessness, or confusion<\/li><li>Color change of fingers and toes when cold and then pain and tingling when warmed up (Raynaud&#8217;s phenomenon)<\/li><li>Enlarged breasts in men<\/li><li>Blood clots<\/li><li>Hearing changes<\/li><li>Reduced tear flow<\/li><li>The visual disturbance which means that things look yellow<\/li><li>Dehydration<\/li><li>Swelling, pain, and\u00a0redness\u00a0of the cheek (\u00a0inflammation\u00a0of the salivary gland)<\/li><li>Swelling in the intestine is called &#8220;intestinal angioedema&#8221; which causes symptoms such as abdominal pain, vomiting, and diarrhea<\/li><li>Increased sun sensitivity<\/li><li>Severe skin flaking, itchy lumpy rash, or other skin reactions such as red rash on the face or forehead<\/li><li>Skin rash or bruising<\/li><li>Stains on the skin and cold limbs<\/li><li>Nail problems (eg loose nails or loosening of the nail from its attachment)<\/li><li>Muscle stiffness or inability to move the jaw (\u00a0tetany\u00a0)<\/li><li>Feeling weak or have muscle cramps<\/li><li>Decreased sexual desire in men or women<\/li><li>Blood in the urine.\u00a0This may be a sign of a kidney problem (interstitial nephritis).<\/li><li>More sugar than normal in the urine<\/li><li>Increased number of certain\u00a0white blood cells\u00a0(\u00a0eosinophilia\u00a0) detected by blood tests<\/li><li>Blood tests that show too few\u00a0blood cells\u00a0in your blood (pancytopenia)<\/li><li>Blood tests that show a change in the number of salts such as\u00a0sodium,\u00a0calcium\u00a0,\u00a0magnesium,\u00a0and chloride in your blood<\/li><li>Slow or worsening reactions<\/li><li>Change of the sense of smell<\/li><li>Difficulty breathing or worsening\u00a0asthma.<\/li><li>Skin and lip cancer (Non-\u00a0melanoma\u00a0skin cancer)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Ramipril \/ Hydrochlorothiazide HEXAL<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store below 30&nbsp;<sup>o<\/sup>&nbsp;C.<\/p>\n\n\n\n<p>Blister<strong>:<\/strong>\u00a0Store in the original package.\u00a0Moisture sensitive.<\/p>\n\n\n\n<p>HDPE jar: Close the jar tightly.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><strong>The active substances are<\/strong>\u00a0ramipril and\u00a0hydrochlorothiazide.<\/p>\n\n\n\n<p><em>2.5 mg \/ 12.5 mg tablets:<\/em><\/p>\n\n\n\n<p>Each tablet contains ramipril 2.5 mg and&nbsp;hydrochlorothiazide&nbsp;12.5 mg.<\/p>\n\n\n\n<p><em>5 mg \/ 25 mg tablets:<\/em><\/p>\n\n\n\n<p>Each tablet contains ramipril 5 mg and&nbsp;hydrochlorothiazide&nbsp;25 mg.<\/p>\n\n\n\n<p><strong>The other ingredients are:<\/strong>&nbsp;sodium bicarbonate, hypromellose, microcrystalline cellulose, corn starch, sodium stearyl fumarate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p><em>Ramipril \/ Hydrochlorothiazide HEXAL 2.5 mg \/ 12.5 mg tablets:<\/em><\/p>\n\n\n\n<p>The tablets are white, oblong with a scoreline on both sides and marked \u201cR 15\u201d on one side.<\/p>\n\n\n\n<p><em>Ramipril \/ Hydrochlorothiazide HEXAL 5 mg \/ 25 mg tablets:<\/em><\/p>\n\n\n\n<p>The tablets are white, oblong with a scoreline on both sides and marked \u201cR 30\u201d on one side.<\/p>\n\n\n\n<p>The tablets are packaged in aluminum\/aluminum blisters in a carton or a tablet jar of HDPE.\u00a0The jar has a screw cap made of PP with desiccant (white silica gel).<\/p>\n\n\n\n<p>HDPE can: 14, 20, 28, 30, 50, 98, 100 tablets.<\/p>\n\n\n\n<p>Blister: 14, 20, 28, 30, 50, 98, 100 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>HEXAL A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>LEK SA, Ul.&nbsp;Domaniewska 50 C, 02-672 Warsaw, Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ramipril \/ Hydrochlorothiazide HEXAL is a combination of two medicines called ramipril and hydrochlorothiazide .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[3664,22278,22281,4301,22268,22271,22280,7947,4300,22279,22269,22270],"class_list":["post-21592","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-hydrochlorothiazide","tag-hydrochlorothiazide-hexal","tag-hydrochlorothiazide-hexal-tablet","tag-hydrochlorothiazide-tablet","tag-ramipril","tag-ramipril-tablet","tag-what-hydrochlorothiazide-hexal-is-used-for","tag-what-hydrochlorothiazide-is-used-for","tag-what-is-hydrochlorothiazide","tag-what-is-hydrochlorothiazide-hexal","tag-what-is-ramipril","tag-what-ramipril-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21592"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21592\/revisions"}],"predecessor-version":[{"id":21623,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21592\/revisions\/21623"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}