Breast-feeding<\/strong><\/p>\n\n\n\nYou should not take Ramipril \/ Hydrochlorothiazide Krka if you are breastfeeding.<\/p>\n\n\n\n
Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
You may feel dizzy when taking Ramipril \/ Hydrochlorothiazide Krka. This is more likely to happen when you start taking Ramipril \/ Hydrochlorothiazide Krka or if you start taking a higher dose. If this happens, do not drive or use any tools or machines.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Ramipril \/ Hydrochlorothiazide Krka contains sodium<\/h2>\n\n\n\n
This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per tablet, ie essentially ‘sodium-free’.\u00a0is next to “sodium-free”.<\/p>\n\n\n\n
How to use Ramipril \/ Hydrochlorothiazide Krka<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
Dosage<\/strong><\/p>\n\n\n\n- the drug should be swallowed and taken at the same time each day, usually in the morning<\/li>
- swallow the tablets with liquid<\/li>
- do not crush or chew the tablets<\/li><\/ul>\n\n\n\n
What dose should you take?<\/strong><\/p>\n\n\n\nTreatment of high blood pressure<\/em><\/p>\n\n\n\nYour doctor will adjust the dose until your blood pressure is under control.<\/p>\n\n\n\n
Older<\/em><\/p>\n\n\n\nYour doctor will reduce the starting dose and adjust your treatment at a slower pace.<\/p>\n\n\n\n
If you use more Ramipril \/ Hydrochlorothiazide Krka than you should <\/h2>\n\n\n\n
Contact a doctor or see the emergency department at the nearest hospital as soon as possible. Do not drive to the hospital, ask someone else to drive you or call an ambulance. Bring your medicine pack. This is so that the doctor knows what you have taken.<\/p>\n\n\n\n
If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n
If you forget to use Ramipril \/ Hydrochlorothiazide Krka<\/h2>\n\n\n\n
If you forget to take a dose, take your normal dose at the next dose.<\/p>\n\n\n\n
Do not take a double dose to make up for a forgotten tablet.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Stop taking <\/strong>Ramipril \/ Hydrochlorothiazide Krka and see a doctor immediately if you notice any of the following serious side effects – you may need urgent medical attention:<\/strong><\/p>\n\n\n\n- swelling of the face, lips, or throat which makes it difficult to swallow or breathe, but also\u00a0itching\u00a0and rash.\u00a0This may be a sign of a severe\u00a0allergic reaction\u00a0to Ramipril \/ Hydrochlorothiazide Krka.<\/li>
- severe skin reactions including rash, cold sores, worsening of skin conditions,\u00a0redness, blistering, or skin rash (such as Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis,\u00a0or erythema multiforme).<\/li>
- acute\u00a0respiratory distress syndrome (signs of severe shortness of breath, fever, weakness, and confusion) (very rare (may affect up to 1 in 10,000 people)).<\/li><\/ul>\n\n\n\n
Tell your doctor immediately if you experience:<\/strong><\/p>\n\n\n\n- increased heart rate, irregular or severe heartbeat (\u00a0palpitation\u00a0), chest pain, chest tightness, or more serious problems including heart attack and\u00a0stroke<\/li>
- shortness of breath, cough, and fever for 2-3 days, and decreased appetite.\u00a0This can be a sign of lung problems including pneumonia<\/li>
- bruising that occurs more easily than usual, prolonged bleeding time, signs of bleeding (eg bleeding in the gums), purple spots on the skin, spots on the skin or increased susceptibility to infection, sore throat and fever, fatigue, weakness, dizziness or pale skin.\u00a0This could be a sign of blood or bone marrow problems<\/li>
- or severe abdominal pain that can be felt in the back.\u00a0This may be a sign of inflammation of the pancreas (\u00a0pancreatitis\u00a0).<\/li>
- fever, chills, fatigue, loss of appetite, abdominal pain, nausea, yellowing of the skin or eyes (jaundice).\u00a0This can be a sign of liver problems such as\u00a0inflammation\u00a0of the liver (\u00a0hepatitis\u00a0) or other liver damage.<\/li><\/ul>\n\n\n\n
Other side effects include:<\/em><\/p>\n\n\n\nTell your doctor if any of the following become serious or persist for more than a few days.<\/strong><\/p>\n\n\n\nCommon<\/strong> (may affect up to 1 in 10 people):<\/p>\n\n\n\n- headache, fatigue, or feeling of weakness<\/li>
- dizziness.\u00a0This is more likely to happen when you start taking Ramipril \/ Hydrochlorothiazide Krka or if you take a higher\u00a0dose<\/li>
- abnormally low\u00a0blood pressure\u00a0(\u00a0hypotension\u00a0), especially when standing or sitting up<\/li>
- dry cough or\u00a0bronchitis<\/li>
- blood tests that show higher blood sugar than normal.\u00a0If you have\u00a0diabetes, this can make your\u00a0diabetes worse<\/li>
- blood tests that show more\u00a0uric acid\u00a0or more fatty acids than normal<\/li>
- sore, red, and swollen joints<\/li>
- blood tests that show more\u00a0potassium\u00a0than normal in your blood<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people):<\/p>\n\n\n\n- skin rash with or without swelling<\/li>
- hot flashes, fainting<\/li>
- balance problem (fraud)<\/li>
- itching\u00a0and abnormal sensations in the skin such as numbness, tingling, burning sensation, or an ant crawling (\u00a0paresthesia\u00a0)<\/li>
- altered or lost taste experience<\/li>
- sleep disorders<\/li>
- depression, anxiety, increased nervousness or restlessness<\/li>
- stuffy nose, sinusitis, shortness of breath<\/li>
- inflammation\u00a0of the gums (\u00a0gingivitis\u00a0), swelling of the mouth<\/li>
- red, itchy, swollen, or watery eyes<\/li>
- earrings<\/li>
- dimsyn<\/li>
- hair loss<\/li>
- chest pain<\/li>
- muscle pain<\/li>
- constipation, abdominal pain<\/li>
- indigestion or nausea<\/li>
- increased urination<\/li>
- increased sweating or thirst<\/li>
- lost or decreased appetite (\u00a0anorexia\u00a0), feeling of decreased hunger<\/li>
- increased or irregular heartbeat<\/li>
- swollen arms and legs.\u00a0This may be a sign that your body is storing more water than usual<\/li>
- fever<\/li>
- sexual inability in men decreased sexual desire in men or women<\/li>
- blood tests showing changes in the number of\u00a0red blood cells, white blood cells, or\u00a0platelets\u00a0or a decrease in the level of\u00a0hemoglobin<\/li>
- blood tests that show changes in your liver function, pancreas, or kidney function<\/li>
- blood tests that show less\u00a0potassium\u00a0in your blood<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people):<\/p>\n\n\n\n- confusion<\/li>
- blemishes on the skin and cold limbs (hands and feet)<\/li><\/ul>\n\n\n\n
Very rare<\/strong> (may affect up to 1 in 10,000 people):<\/p>\n\n\n\n- vomiting, diarrhea, or heartburn<\/li>
- red and swollen tongue or\u00a0dry mouth<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users):<\/p>\n\n\n\n- skin and lip cancer (Non-\u00a0melanoma\u00a0skin cancer)<\/li>
- concentrated urine (dark-colored), nausea or vomiting, muscle cramps, confusion, and seizures, which may be due to incorrect secretion of\u00a0antidiuretic hormone\u00a0(\u00a0ADH\u00a0).\u00a0If you experience these symptoms, contact your doctor as soon as possible.<\/li><\/ul>\n\n\n\n
Other reported side effects:<\/strong><\/p>\n\n\n\nTell your doctor if any of the following become serious or persist for more than a few days:<\/p>\n\n\n\n
- concentration difficulties<\/li>
- color change of fingers and toes in cold and then pain and creeps when warmed up (Raynaud’s phenomenon)<\/li>
- enlarged breasts in men<\/li>
- blood clots<\/li>
- hearing changes<\/li>
- reduced tear flow<\/li>
- the visual disturbance which means that things look yellow<\/li>
- impaired vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or\u00a0acute\u00a0narrow-angle glaucoma\u00a0)<\/li>
- dehydration<\/li>
- swelling, pain, and\u00a0redness\u00a0of the cheek (\u00a0inflammation\u00a0of the salivary gland)<\/li>
- swelling in the stomach called “intestinal angioedema” which causes symptoms such as abdominal pain, vomiting, and diarrhea<\/li>
- increased sun sensitivity<\/li>
- severe skin flaking, itchy lumpy rash, or other skin reactions such as red rash on the face or forehead<\/li>
- skin rash or bruising<\/li>
- nail problems (eg loose nails or the nail coming loose from its bracket)<\/li>
- muscle stiffness or inability to move the jaw (\u00a0tetany\u00a0)<\/li>
- the feeling of weakness or cramps in the muscles<\/li>
- blood in the urine.\u00a0This may be a sign of a kidney problem (interstitial nephritis)<\/li>
- more sugar than normal in the urine<\/li>
- increased number of certain\u00a0blood cells\u00a0(\u00a0eosinophilia\u00a0) detected by blood tests<\/li>
- blood tests that show too few\u00a0blood cells\u00a0in your blood (pancytopenia)<\/li>
- blood tests that show changes in the number of salts such as\u00a0sodium,\u00a0calcium,\u00a0magnesium,\u00a0and chloride in the blood<\/li>
- slow or worsening reactions<\/li>
- change of sense of smell<\/li>
- difficulty breathing or worsening\u00a0asthma<\/li><\/ul>\n\n\n\n
How to store Ramipril \/ Hydrochlorothiazide Krka<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Do not store above 30 \u00b0 C.<\/p>\n\n\n\n
Store in the original package. Moisture sensitive.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substances are ramipril and\u00a0hydrochlorothiazide\u00a0.2.5 mg \/ 12.5 mg tablets: Each tablet contains 2.5 mg ramipril and 12.5 mg\u00a0hydrochlorothiazide\u00a0.5 mg \/ 25 mg tablets: Each tablet contains 5 mg ramipril and 25 mg\u00a0hydrochlorothiazide\u00a0.<\/li>
- The other ingredients are hypromellose, microcrystalline cellulose, pregelatinized maize starch, and sodium stearyl fumarate.\u00a0See section 2 “Ramipril \/ Hydrochlorothiazide Krka contains sodium”.<\/li><\/ul>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
2.5 mg \/ 12.5 mg tablets: white to off-white, round tablets, with beveled edges and marked C on one side.\u00a0Tablet diameter: 5.5 mm.<\/p>\n\n\n\n
5 mg \/ 25 mg tablets: white to off-white, round tablets, with beveled edges, scored on one side and marked with S on the other side of the tablet.\u00a0Tablet diameter: 7.5 mm.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n
Ramipril \/ Hydrochlorothiazide Krka is available in cartons of 14, 28, 30, 56, 98, and 100 tablets in blisters.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/strong><\/p>\n\n\n\nKrka, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nKrka, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n
TAD Pharma GmbH, Heinz-Lohmann-Stra\u00dfe 5, 27472 Cuxhaven, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"
Ramipril \/ Hydrochlorothiazide Krka is a combination of two medicines called ramipril and hydrochlorothiazide .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18529],"tags":[3664,7937,22283,4301,22268,22271,7947,7941,7938,22282,22270],"class_list":["post-21588","post","type-post","status-publish","format-standard","hentry","category-medicines","category-r","tag-hydrochlorothiazide","tag-hydrochlorothiazide-krka","tag-hydrochlorothiazide-krka-tablet","tag-hydrochlorothiazide-tablet","tag-ramipril","tag-ramipril-tablet","tag-what-hydrochlorothiazide-is-used-for","tag-what-hydrochlorothiazide-krka-is-used-for","tag-what-is-hydrochlorothiazide-krka","tag-what-ramipril","tag-what-ramipril-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21588","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21588"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21588\/revisions"}],"predecessor-version":[{"id":21626,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21588\/revisions\/21626"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21588"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21588"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21588"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}