{"id":21513,"date":"2022-05-26T06:48:20","date_gmt":"2022-05-26T06:48:20","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21513"},"modified":"2022-05-26T13:57:26","modified_gmt":"2022-05-26T13:57:26","slug":"questran","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/questran\/","title":{"rendered":"Questran &#8211; Cholestyramine uses, dose and side effects"},"content":{"rendered":"\n<p>4 g\u00a0powder for\u00a0oral\u00a0suspension,\u00a0sachet<br>cholestyramine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Questran is and what it is used for<\/h2>\n\n\n\n<p>Questran is used:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>to lower elevated levels of blood fats when dietary treatment has not had sufficient effect.<\/li><li>in case of skin itching caused by an obstruction in the bile ducts.<\/li><li>in diarrhea caused by too much bile acids in the intestine.<\/li><\/ul>\n\n\n\n<p>In the small intestine, Questran binds bile acids, which are formed from\u00a0cholesterol.\u00a0In the new formation of bile acids,\u00a0cholesterol\u00a0is taken from the blood, the content of which thereby decreases.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Questran<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Questran<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to cholestyramine or any of the other ingredients of this medicine (listed in section 6).<\/li><li>at a complete stop in the bile ducts.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Questran:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have\u00a0inflammatory\u00a0bowel disease.<\/li><li>with very long-term treatment, as it can reduce the uptake of fat-soluble\u00a0vitamins\u00a0and a lack of\u00a0vitamin\u00a0K can increase the tendency to bleed.\u00a0Vitamins\u00a0A, D, and K may in some cases need to be given prophylactically.<\/li><li>if you have constipation.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Questran<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The effect of certain other medicines may be affected if Questran is taken at the same time as these.&nbsp;Therefore, consult your doctor before using other medicines at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Experience with the use of Questran during pregnancy is limited.&nbsp;Therefore, always consult a doctor before using Questran during pregnancy.<\/p>\n\n\n\n<p>Cholestyramine does not pass into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Questran contains sucrose and propylene glycol<\/h2>\n\n\n\n<p>Contains 3.79 grams of sucrose per\u00a0sachet\u00a0.\u00a0This should be considered in patients with\u00a0diabetes mellitus.<\/p>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p>May be harmful to teeth.&nbsp;Therefore, be careful with oral hygiene.<\/p>\n\n\n\n<p>This medicine contains 97.5 mg of propylene glycol per\u00a0sachet.<\/p>\n\n\n\n<p>If your child is younger than 4 weeks or weighs less than 8 kg, consult a doctor or pharmacist before using the medicine, especially if the child is taking other medicines containing propylene glycol or alcohol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Questran<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;for&nbsp;<em>adults<\/em>&nbsp;is 1-2 sachets 2-3 times daily.<\/p>\n\n\n\n<p><strong>Children:&nbsp;<\/strong>The dose&nbsp;is determined by the doctor, who adjusts it individually to the child&#8217;s weight or age.<\/p>\n\n\n\n<p>To avoid upset stomach and constipation, start with only \u00bd\u00a0sachet\u00a0daily during the first week and then increase the\u00a0dose\u00a0one week until the prescribed\u00a0dose\u00a0is reached.\u00a0Other medicines should be taken 1 hour before or 4-6 hours after Questran to prevent the absorption of the medicines from being affected.<\/p>\n\n\n\n<p>The powder is mixed with water, juice, juice, or other beverage.\u00a0It is also possible to mix in soups or finely chopped fruit, such as apple puree or crushed pineapple.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Questran than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0a child ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported during treatment with Questran:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>altered prothrombin values,<\/li><li>weight gain, weight loss,<\/li><li>tendency to bleed decreased protein content in the blood,\u00a0anemia, lymph node disease, large bruises,<\/li><li>headache, dizziness, fainting, drowsiness, nerve pain, tingling, taste disturbances,<\/li><li>night blindness\u00a0(with\u00a0vitamin\u00a0A deficiency),\u00a0inflammation\u00a0of the grape membrane of the eye,<\/li><li>tinnitus, dizziness,<\/li><li>asthma, wheezing, labored breathing, hiccups,<\/li><li>constipation,\u00a0inflammation\u00a0of the pancreas, discomfort in the stomach, flatulence, nausea, vomiting, diarrhea,\u00a0dyspepsia, fatty diarrhea,\u00a0inflammation\u00a0of the tongue, rectal problems, bleeding in the gastrointestinal tract, rectal bleeding, discoloration of stool, hemorrhoidal bleeding,\u00a0duodenal\u00a0hemorrhage\u00a0difficulty swallowing, pain in the rectum, belching,\u00a0acute\u00a0abdomen,\u00a0caries, bleeding in the mouth, constipation,\u00a0inflammation\u00a0of the colon,<\/li><li>blood in the urine, difficulty passing water, abnormal urine odor, increased urine output,<\/li><li>redness, skin irritation,\u00a0hives,<\/li><li>osteoporosis, back pain, muscle pain, joint pain, joint inflammation,<\/li><li>vitamin\u00a0A deficiency,\u00a0vitamin\u00a0K deficiency,\u00a0vitamin\u00a0D deficiency, high levels of acids, excess chlorine in the blood (in children),\u00a0anorexia,<\/li><li>fatigue,\u00a0edema,<\/li><li>gallstones, gallbladder calcification, gallbladder pain, abnormal liver function values,<\/li><li>increased sexual desire, anxiety.<\/li><\/ul>\n\n\n\n<p>With long-term treatment, a lack of\u00a0vitamin\u00a0K can increase the tendency to bleed and a lack of\u00a0vitamin\u00a0A can in rare cases cause\u00a0night blindness.\u00a0Osteoporosis and lowered <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a> in the blood have also been reported.<\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get\u00a0any side effects, talk to your doctor or pharmacist.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly (see details below).\u00a0By reporting\u00a0side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Questran<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is cholestyramine 4 g per\u00a0sachet\u00a0.<\/li><li>The other ingredients are sucrose, acacia gum, propylene glycol alginate, anhydrous citric acid, polysorbate 80, and flavoring (orange).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Carton of 50 sachets.<\/p>\n\n\n\n<p>Carton of 4 x 50 sachets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>CHEPLAPHARM Arzneimittel GmbH<\/p>\n\n\n\n<p>Ziegelhof 24<\/p>\n\n\n\n<p>17489 Greifswald<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Farmea<\/p>\n\n\n\n<p>10 rue Bouche Thomas<\/p>\n\n\n\n<p>ZAC d&#8217;Orgemont<\/p>\n\n\n\n<p>49000 Angers<\/p>\n\n\n\n<p>France<\/p>\n","protected":false},"excerpt":{"rendered":"<p>4 g powder for oral suspension , sachet<br \/>\ncholestyramine<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18528],"tags":[15147,22267,15143,15146,22263,22266,15145,15144,22264,22265],"class_list":["post-21513","post","type-post","status-publish","format-standard","hentry","category-medicines","category-q","tag-benefits-of-cholestyramine","tag-benefits-of-questran","tag-cholestyramine","tag-cholestyramine-side-effects","tag-questran","tag-questran-side-effects","tag-what-cholestyramine-is-used-for","tag-what-is-cholestyramine","tag-what-is-questran","tag-what-questran-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21513","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21513"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21513\/revisions"}],"predecessor-version":[{"id":21570,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21513\/revisions\/21570"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21513"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21513"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21513"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}