{"id":21263,"date":"2022-05-18T07:56:49","date_gmt":"2022-05-18T07:56:49","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21263"},"modified":"2022-05-18T15:51:02","modified_gmt":"2022-05-18T15:51:02","slug":"procoralan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/procoralan\/","title":{"rendered":"Procoralan &#8211; Ivabradine uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg, 7.5 mg&nbsp;film-coated tablets<br>ivabradine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Procoralan is and what it is used for<\/h2>\n\n\n\n<p>Procoralan (&nbsp;ivabradine&nbsp;) is a heart medicine used to treat<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Symptomatic stable\u00a0angina pectoris\u00a0(which causes chest pain) in adult patients whose\u00a0heart rate\u00a0is above or equal to 70 beats per minute.\u00a0It is used in adult patients who are intolerant or unable to use beta-blockers.\u00a0It is also used in combination with\u00a0beta-blockers\u00a0in adult patients whose condition cannot be completely controlled with\u00a0beta-blockers\u00a0alone.<\/li><li>Chronic\u00a0heart failure\u00a0in adult patients whose\u00a0heart rate\u00a0is above or equal to 75 beats per minute.\u00a0It is used in combination with standard treatment, including treatment with beta-blockers\u00a0or when beta-blockers\u00a0must not be used or not tolerated.<\/li><\/ul>\n\n\n\n<p>Stable&nbsp;angina pectoris&nbsp;(commonly referred to as &#8220;angina&#8221;):<\/p>\n\n\n\n<p>Stable angina is a heart disease that occurs when the heart does not get enough oxygen.&nbsp;The most common symptom of angina is chest pain or discomfort.<\/p>\n\n\n\n<p>About&nbsp;chronic&nbsp;heart failure:<\/p>\n\n\n\n<p>Chronic\u00a0heart failure\u00a0is a heart disease that occurs when your heart cannot pump enough blood to the rest of your body.\u00a0The most common symptoms of\u00a0heart failure\u00a0are shortness of breath, fatigue, fatigue, and swollen ankles.<\/p>\n\n\n\n<p>How does Procoralan work?<\/p>\n\n\n\n<p>The specific heart rate lowering effect of&nbsp;ivabradine&nbsp;helps to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>control and reduce the number of angina attacks by reducing the heart&#8217;s oxygen needs<\/li><li>improve heart function and life expectancy in patients with\u00a0chronic\u00a0heart failure.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Procoralan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Procoralan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0ivabradine\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if your resting heart rate before treatment is too low (less than 70 beats per minute)<\/li><li>if you suffer from\u00a0cardiogenic\u00a0shock\u00a0(a heart condition that is treated in a hospital)<\/li><li>if you have a heart rhythm disorder (sick sinus syndrome, SA block,\u00a0AV block\u00a0grade III)<\/li><li>if you have a heart attack<\/li><li>if you have very low\u00a0blood pressure<\/li><li>if you have\u00a0unstable angina\u00a0(a serious condition where the chest pain is very common and occurs with or without exertion)<\/li><li>if you have\u00a0heart failure\u00a0that has recently gotten worse<\/li><li>if your heart rhythm is exclusively maintained by a pacemaker<\/li><li>if you have severe liver problems<\/li><li>if you are taking medicines to treat fungal infections (such as\u00a0ketoconazole, itraconazole), macrolide antibiotics (such as josamycin, clarithromycin, telithromycin, or erythromycin given orally), or medicines for\u00a0HIV\u00a0infections\u00a0(such as nelfinavir, ritonavir) or fax of depression) or\u00a0diltiazem, verapamil (used to treat high\u00a0blood pressure\u00a0or\u00a0angina pectoris\u00a0)<\/li><li>if you are a woman of childbearing potential and do not use a safe method of contraception<\/li><li>if you are pregnant or trying to become pregnant<\/li><li>if you are breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Procoralan<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have arrhythmia (such as irregular heartbeat, palpitations, increased chest pain) or persistent\u00a0heart fibrillation\u00a0(a type of irregular heartbeat), or an abnormal\u00a0electrocardiogram\u00a0(\u00a0ECG\u00a0), called &#8220;long\u00a0QT\u00a0syndrome&#8221;.<\/li><li>if you have symptoms such as fatigue, dizziness, or shortness of breath (this may mean that the heart slows down too much)<\/li><li>if you suffer from symptoms of\u00a0atrial fibrillation\u00a0(unusually high resting heart rate (over 110 beats per minute) or irregular resting heart rate for no apparent reason, making it difficult to measure)<\/li><li>if you have recently had\u00a0a\u00a0stroke<\/li><li>if you suffer from\u00a0mild to moderate\u00a0blood pressure<\/li><li>if your\u00a0blood pressure\u00a0is not completely controlled, especially after changes in your blood pressure-lowering treatment<\/li><li>if you suffer from severe\u00a0heart failure\u00a0or\u00a0heart failure\u00a0with an abnormal\u00a0ECG\u00a0called &#8220;branch block&#8221;<\/li><li>if you have\u00a0chronic\u00a0retinal disease<\/li><li>if you have moderate liver problems<\/li><li>if you have severe kidney problems.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you, talk to your doctor immediately before or when you take Procoralan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Do not give this medicine to children or adolescents under 18 years of age.&nbsp;Sufficient information is lacking in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Procoralan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>It is important to inform your doctor if you are using any of the following medicines, as a dose adjustment of Procoralan or follow-up may be necessary:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fluconazole\u00a0(an antifungal medicine)<\/li><li>rifampicin (\u00a0antibiotic\u00a0)<\/li><li>barbiturates\u00a0(for insomnia or\u00a0epilepsy\u00a0)<\/li><li>phenytoin\u00a0(for\u00a0epilepsy\u00a0)<\/li><li><em>Hypericum<\/em> perforatum\u00a0or St. John&#8217;s\u00a0wort\u00a0(a natural remedy for mild depression)<\/li><li>QT-prolonging medications to treat either heart rhythm disorders or other conditions:<ul><li>quinidine,\u00a0disopyramide, ibutilide, sotalol,\u00a0amiodarone\u00a0(for\u00a0cardiac arrhythmias\u00a0)<\/li><li>bepridil (against\u00a0angina pectoris\u00a0)<\/li><li>certain medicines for anxiety, schizophrenia, or other\u00a0psychoses\u00a0(such as pimozide, ziprasidone, sertindole)<\/li><li>malaria drugs (such as mefloquine and halofantrine)<\/li><li>intravenous\u00a0erythromycin (an\u00a0antibiotic\u00a0)<\/li><li>pentamidine (antiparasitic agent)<\/li><li>cisapride (for acid reflux)<\/li><\/ul><\/li><li>Some types of\u00a0diuretics\u00a0can cause a decrease in potassium levels in the blood, such as\u00a0furosemide,\u00a0hydrochlorothiazide, and indapamide (used to treat\u00a0edema and high\u00a0blood pressure\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Procoralan with food and drink<\/h2>\n\n\n\n<p>Avoid grapefruit juice during treatment with Procoralan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Do not use Procoralan if you are pregnant or planning to become pregnant (see &#8216;Do not take Procoralan&#8217;).<\/p>\n\n\n\n<p>Ask your doctor if you are pregnant and have used Procoralan.<\/p>\n\n\n\n<p>Do not use Procoralan if you can get pregnant unless you use a safe method of contraception (see &#8220;Do not take Procoralan&#8221;).<\/p>\n\n\n\n<p>Do not use Procoralan if you are breastfeeding (see &#8220;Do not take Procoralan&#8221;).\u00a0Ask your doctor if you are breastfeeding or plan to start breastfeeding as breastfeeding should be stopped if you are using Procoralan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Procoralan may cause short-term light phenomena (a temporary increase in light intensity in the&nbsp;field&nbsp;of view and see \u201cPossible side effects\u201d).&nbsp;If you get this, be careful with driving and using machines when there may be sudden changes in light intensity, especially when driving at night.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Procoralan contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Procoralan<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Procoralan should be taken with meals.<\/p>\n\n\n\n<p>The Procoralan 5 mg tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n<p>If you are being treated for stable&nbsp;angina pectoris<\/p>\n\n\n\n<p>The starting dose should not exceed one Procoralan 5 mg tablet twice daily.\u00a0If you still have angina symptoms and have tolerated a\u00a0dose\u00a0of 5 mg twice daily, the\u00a0dose\u00a0may be increased.\u00a0The maintenance dose should not exceed 7.5 mg twice daily.\u00a0Your doctor will prescribe the right\u00a0dose\u00a0for you.\u00a0The usual\u00a0dose\u00a0is one tablet in the morning and one tablet in the evening.\u00a0In some cases (eg if you are 75 years or older), your doctor may prescribe half a\u00a0dose, ie half a tablet of Procoralan 5 mg (equivalent to 2.5 mg\u00a0ivabradine\u00a0) in the morning and half a 5 mg tablet in the evening.<\/p>\n\n\n\n<p>If you are being treated for&nbsp;chronic&nbsp;heart failure<\/p>\n\n\n\n<p>The usual recommended starting dose is one tablet of Procoralan 5 mg twice daily, which can be increased to one tablet of Procoralan 7.5 mg twice daily if needed.\u00a0Your doctor will assess which\u00a0dose\u00a0is right for you.\u00a0The usual\u00a0dose\u00a0is one tablet in the morning and one tablet in the evening.\u00a0In some cases (eg if you are 75 years or older), your doctor may prescribe half a\u00a0dose of\u00a0one, ie half a Procoralan 5 mg tablet (equivalent to 2.5 mg\u00a0ivabradine\u00a0) in the morning and half a 5 mg tablet in the evening.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Procoralan than you should<\/h2>\n\n\n\n<p>A high&nbsp;dose&nbsp;of Procoralan can make you feel short of breath or tired because your heart is slowing down too much.&nbsp;Contact your doctor immediately if this happens.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Procoralan<\/h2>\n\n\n\n<p>If you forget to take Procoralan,\u00a0take the next\u00a0dose at the usual time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>The calendar on the tablet blister should help you remember when you last took a tablet of Procoralan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Procoralan<\/h2>\n\n\n\n<p>Because treatment for angina (angina) or&nbsp;chronic&nbsp;heart failure&nbsp;is usually lifelong, you should consult your doctor before stopping treatment with this product.<\/p>\n\n\n\n<p>If you have the impression that the effect of Procoralan is too strong or too weak, talk to your doctor or pharmacist.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The most common\u00a0side effects\u00a0of this medicine are dose-dependent and related to their mechanism of action:<\/p>\n\n\n\n<p><em>Very common<\/em>&nbsp;(may affect more than 1 in 10 people)<\/p>\n\n\n\n<p>Light phenomena in the\u00a0field\u00a0of view (short moments with increased light intensity, usually caused by sudden changes in light conditions).\u00a0They can also be described as a light ring, colored flashes, image resolution, or multiple images.\u00a0They usually appear within the first two months of treatment, after which they may appear and disappear repeatedly during or after treatment.<\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<p>Impact on the work of the heart (symptoms are slow&nbsp;pulse&nbsp;).&nbsp;They occur mainly within the first 2 to 3 months after the start of treatment.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have also been reported:<\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<p>Irregular, rapid contraction of the heart (\u00a0atrial fibrillation\u00a0), abnormal perception of heartbeat (slow heart rate, ventricular extrasystole,\u00a0AV block\u00a0grade I [prolonged PQ interval on\u00a0ECG\u00a0]), uncontrolled\u00a0blood pressure, headache, dizziness, and blurred vision (blurred vision).<\/p>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<p>Palpitations and extra heartbeat, nausea, constipation, diarrhea, abdominal pain, dizziness, difficulty breathing (\u00a0dyspnoea\u00a0), muscle spasms, high levels of\u00a0uric acid\u00a0in the blood, increase in the number of\u00a0eosinophils\u00a0(a type of\u00a0white blood cell\u00a0), and elevated levels of\u00a0creatinine\u00a0in the blood (a breakdown of product )\u00a0muscles), skin rash,\u00a0angioedema\u00a0(such as swelling of the face, tongue or throat, difficulty breathing or swallowing), low\u00a0blood pressure, fainting, tiredness, feeling weak, abnormal\u00a0ECG\u00a0heart pattern, double vision, impaired vision.<\/p>\n\n\n\n<p><em>Rare<\/em>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<p>Hives,\u00a0itching, reddening of the skin, feeling sick.<\/p>\n\n\n\n<p><em>Very rare<\/em>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<p>Irregular heartbeat (&nbsp;AV block&nbsp;grade II,&nbsp;AV block&nbsp;grade III, sick sinus syndrome).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Procoralan<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is&nbsp;ivabradine&nbsp;(as hydrochloride).<\/p>\n\n\n\n<p>Procoralan 5 mg film-coated tablets: one film-coated tablet contains 5 mg&nbsp;ivabradine&nbsp;as hydrochloride.<\/p>\n\n\n\n<p>Procoralan 7.5 mg film-coated tablets: one film-coated tablet contains 7.5 mg&nbsp;ivabradine&nbsp;as hydrochloride.<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tablet core:\u00a0lactose monohydrate, magnesium stearate (E 470 B), maize starch, maltodextrin, anhydrous\u00a0colloidal\u00a0silica (E 551)<\/li><li>film coating: hypromellose (E 464), titanium dioxide (E 171), macrogol 6000,\u00a0glycerol\u00a0(E 422), magnesium stearate (E 470 B), yellow iron oxide (E 172), red iron oxide (E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Procoralan 5 mg tablets are salmon-colored, oblong, film-coated tablets with a notch on both sides, debossed with \u201c5\u201d on one side and\u00a0the other.<\/td><\/tr><tr><td>Procoralan 7.5 mg tablets are salmon-colored, triangular, film-coated tablets debossed with \u201c7.5\u201d on one side and\u00a0the other.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The tablets are available in&nbsp;calendar&nbsp;packs (Aluminum \/ PVC blisters) with 14, 28, 56, 84, 98, 100 or 112 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Servier Laborierires Servier<\/p>\n\n\n\n<p>50, rue Carnot<\/p>\n\n\n\n<p>92284 Suresnes cedex- France<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>The Laboratories Servier Industrie<\/p>\n\n\n\n<p>905 route de Saran<\/p>\n\n\n\n<p>45520 Judy &#8211; France<\/p>\n\n\n\n<p>Servier (Ireland) Industries Ltd<\/p>\n\n\n\n<p>Gorey Road<\/p>\n\n\n\n<p>Arklow &#8211; Co.&nbsp;Wicklow &#8211; Ireland<\/p>\n\n\n\n<p>Przedsiebiorstwo Farmaceutyczne ANPHARM SA<\/p>\n\n\n\n<p>ul.&nbsp;Annopol 6B &#8211; 03-236 Warsaw &#8211; Poland<\/p>\n\n\n\n<p>Servier Laboratorios, SL<\/p>\n\n\n\n<p>Avda.\u00a0de Los Madro\u00f1os, 33<\/p>\n\n\n\n<p>28043 Madrid<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>SA Servier Benelux NVTel: +32 (0) 2 529 43 11<\/td><td><strong>Lithuania<\/strong>UAB &#8220;SERVIER PHARMA&#8221;Tel: +370 (5) 2 63 86 28<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Medical LODG serviceTel: +359 2 921 57 00<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>SA Servier Benelux NVTel: +32 (0) 2 529 43 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Servier sroTel: +420 222 118 111<\/td><td><strong>Hungary<\/strong>Servier Hungaria Kft.Tel .: + 36 1 238 77 99<\/td><\/tr><tr><td><strong>Denmark<\/strong>Servier Danmark A \/ STel: +45 36 44 22 60<\/td><td><strong>Malta<\/strong>VJ Salomone Pharma LtdTel: + 356 21 22 01 74<\/td><\/tr><tr><td><strong>Germany<\/strong>Servier Deutschland GmbHTel: +49 (0) 89 57095 01<\/td><td><strong>The Netherlands<\/strong>Servier Nederland Farma BVTel: +31 (0) 71 5246700<\/td><\/tr><tr><td><strong>Eesti<\/strong>Servier Laboratories O\u00dcTel: + 372 664 5040<\/td><td><strong>Norway<\/strong>Servier Danmark A \/ STel: +45 36 44 22 60<\/td><\/tr><tr><td><strong>Greece<\/strong>\u0395\u03a0\u0395 \u0395\u039b\u039b\u0391\u03a3 \u03a6\u0391\u03a1\u039c\u0391\u039a\u0395\u03a5\u03a4\u0399\u039a\u0397 \u0395\u03a0\u0395:\u0397\u03bb: +30 210 939 1000<\/td><td><strong>Austria<\/strong>Servier Austria GmbHTel: +43 (1) 524 39 99<\/td><\/tr><tr><td><strong>Spain<\/strong>Servierios Servier SLTel: +34 91 748 96 30<\/td><td><strong>Poland<\/strong>Servier Polska SP.&nbsp;Z OOTel .: + 48 (0) 22 594 90 00<\/td><\/tr><tr><td><strong>France<\/strong>Servier Laborierires ServierTel: +33 (0) 1 55 72 60 00<\/td><td><strong>Portugal<\/strong>Servier Portugal, LdaTel: +351 21 312 20 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Servier Pharma, dooTel .: +385 (0) 1 3016 222<\/td><td><strong>Romania<\/strong>Servier Pharma SRLTel: +4 021 528 52 80<\/td><\/tr><tr><td><strong>Ireland<\/strong>Servier Laboratories (Ireland) Ltd.Tel: +353 (0) 1 663 8110<\/td><td><strong>Slovenia<\/strong>Servier Pharma dooTel: + 386 (0) 1 563 48 11<\/td><\/tr><tr><td><strong>Iceland<\/strong>Servier LaboratoriesC \/ o Icepharma hfPhone: +354 540 8000<\/td><td><strong>Slovak Republic<\/strong>Servier Slovensko spol.&nbsp;s roTel: +421 (0) 2 5920 41 11<\/td><\/tr><tr><td><strong>Italy<\/strong>Servier Italia SpATel: +39 06 669081<\/td><td><strong>Finland \/ Finland<\/strong>Servier Finland OyP. \/ Tel: +358 (0) 9 279 80 80<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>CA Papaellinas Ltd.:\u0397\u03bb: +357 22741741<\/td><td><strong>Sweden<\/strong>Servier Sverige ABTel: +46 (8) 5 225 08 00<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA Servier LatviaTel: + 371 6750 2039<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Servier Laboratories (Ireland) LtdTel: +44 (0) 1 753 666409<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>5 mg, 7.5 mg film-coated tablets<br \/>\nivabradine<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21899,21906,6602,6604,6605,21900,21905,21904,6603,21901,12136,21903],"class_list":["post-21263","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-ivabradine","tag-benefits-of-procoralan","tag-ivabradine","tag-ivabradine-side-effects","tag-ivabradine-tablet","tag-procoralan","tag-procoralan-side-effects","tag-procoralan-tablet","tag-what-is-ivabradine","tag-what-is-procoralan","tag-what-ivabradine-is-used-for","tag-what-procoralan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21263"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21263\/revisions"}],"predecessor-version":[{"id":21308,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21263\/revisions\/21308"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}