{"id":21261,"date":"2022-05-18T07:55:14","date_gmt":"2022-05-18T07:55:14","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21261"},"modified":"2022-05-18T15:51:09","modified_gmt":"2022-05-18T15:51:09","slug":"probecid","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/probecid\/","title":{"rendered":"Probecid &#8211; Probenecid uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg&nbsp;probenecid&nbsp;tablets<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Probecid is and what it is used for<\/h2>\n\n\n\n<p>Probecid contains the active substance probenecid and is used in\u00a0gout\u00a0to relieve gout problems.\u00a0Probecid accelerates the excretion of\u00a0uric acid\u00a0by preventing it from re-entering the kidneys.\u00a0As a result, the blood&#8217;s content of\u00a0uric acid\u00a0decreases, and this leads to reduced gout problems.\u00a0Probecid should be administered continuously.\u00a0When treatment is stopped, the level of\u00a0uric acid\u00a0in the blood rises.\u00a0Probecid has no immediate analgesic effect.\u00a0In acute gout attacks, painkillers must therefore be used.<\/p>\n\n\n\n<p>Probecid also inhibits the excretion of\u00a0penicillin\u00a0via the kidneys and can in some special cases be used to enhance the effect of penicillin.\u00a0If Probecid is given together with\u00a0penicillin, a higher level of\u00a0penicillin\u00a0is therefore obtained in the body for a longer period.\u00a0The penicillin doses can then be given at longer intervals.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Probecid<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Probecid:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to probenecid or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have severe kidney damage.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Probecid<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Probecid may affect or be affected by certain medicines such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>methotrexate (medicines for\u00a0tumors\u00a0and disorders of the immune system)<\/li><li>naproxen, indomethacin, ketorolac (medicines for\u00a0inflammation\u00a0and rheumatism)<\/li><li>zidovudine (antiviral drug)<\/li><li>paracetamol\u00a0(medicine for pain and fever).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy:<\/em>&nbsp;Limited experience of use during pregnancy.&nbsp;Therefore, consult a physician if more than temporary use of Probecid during pregnancy.<\/p>\n\n\n\n<p><em>Lactation:<\/em>\u00a0It is unknown whether Probecid is excreted in human milk.\u00a0Therefore, consult a physician\u00a0<em>before<\/em>\u00a0regular use during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Probecid has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Probecid<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose&nbsp;one should be determined by a doctor who adapts it individually for you.<\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0for\u00a0<em>adults<\/em>\u00a0with\u00a0gout\u00a0is 1 tablet twice daily (the first week, however, 1\/2 tablet twice daily).<\/p>\n\n\n\n<p>You should drink a lot when using Probecid for gout treatment.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;for&nbsp;<em>adults<\/em>&nbsp;when combined with&nbsp;penicillin&nbsp;is 2 tablets twice daily.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Probecid than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0a child ingested the medicine accidentally contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (may affect more than 1 in 100 people<\/em>\u00a0)<em>:<\/em>\u00a0Nausea<\/p>\n\n\n\n<p><em>Rare (&nbsp;<\/em><em>may affect up to 1 in 1,000 people&nbsp;<\/em><em>):<\/em>&nbsp;Skin rash<\/p>\n\n\n\n<p><em>Has been reported&nbsp;<\/em>&nbsp;<em>(occurs in an unknown number of users):<\/em>&nbsp;Coombs positive&nbsp;hemolytic anemia&nbsp;(a special type of&nbsp;anemia&nbsp;)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Probecid<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is probenecid 500 mg.<\/li><li>The other ingredients are gelatin, potato starch,\u00a0colloidal\u00a0silica, stearic acid, talc, and magnesium stearate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p><em>Pack size:<\/em>\u00a0Plastic jar, 50 tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Recipharm Stockholm AB, Jordbro<\/p>\n\n\n\n<p>allphamed PHARBIL Arzneimittel GmbH<\/p>\n\n\n\n<p>Hildebrandstr.&nbsp;10-12<\/p>\n\n\n\n<p>37081 G\u00f6ttingen<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Probecid contains the active substance probenecid and is used in gout to relieve gout problems. Probecid accelerates the excretion of uric acid by preventing it from re-entering the kidneys. As a result, the blood&#8217;s content of uric acid decreases and this leads to reduced gout problems. Probecid should be administered continuously. When treatment is stopped, the level of uric acid in the blood rises . Probecid has no immediate analgesic effect. In acute gout attacks, painkillers must therefore be used.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21919,21922,21923,21914,21917,21918,21920,21915,21921,21916],"class_list":["post-21261","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-probecid","tag-probecid-side-effects","tag-probecid-tablet","tag-probenecid","tag-probenecid-side-effects","tag-probenecid-tablet","tag-what-is-probecid","tag-what-is-probenecid","tag-what-probecid-is-used-for","tag-what-probenecid-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21261"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21261\/revisions"}],"predecessor-version":[{"id":21309,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21261\/revisions\/21309"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}