{"id":21193,"date":"2022-05-17T09:39:07","date_gmt":"2022-05-17T09:39:07","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21193"},"modified":"2022-05-17T15:43:45","modified_gmt":"2022-05-17T15:43:45","slug":"prevenar-13","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/prevenar-13\/","title":{"rendered":"Prevenar 13 | Polysaccharide vaccine uses, dose and side effects"},"content":{"rendered":"\n<p>injection,\u00a0suspension\u00a0in a single-dose vial<br>Polysaccharide vaccine against pneumococcal infections, conjugated,\u00a0adsorbed, 13-valent<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Prevenar 13 is and what it is used for<\/h2>\n\n\n\n<p>Prevenar 13 is a pneumococcal vaccine for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>children aged 6 weeks to 17 years<\/strong>\u00a0who help protect your child against diseases such as\u00a0meningitis\u00a0(\u00a0meningitis\u00a0), sepsis or\u00a0bacteremia\u00a0(bacteria in the blood),\u00a0pneumonia\u00a0(\u00a0pneumonia\u00a0), an ear infection<\/li><li>adults aged 18 years or older\u00a0who help protect against diseases such as\u00a0pneumonia\u00a0(\u00a0pneumonia\u00a0), sepsis or\u00a0bacteremia\u00a0(bacteria in the blood), and\u00a0meningitis\u00a0(\u00a0meningitis\u00a0),<\/li><\/ul>\n\n\n\n<p>caused by 13 different types of the bacterium\u00a0<em>Streptococcus pneumonia<\/em>.<\/p>\n\n\n\n<p>Prevenar 13 protects against 13 types of the bacterium\u00a0Streptococcus pneumoniae\u00a0and replaces Prevenar which protected 7 types.<\/p>\n\n\n\n<p>The vaccine helps the body make antibodies\u00a0that protect you or your child against these diseases.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you or your child receive Prevenar 13<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Prevenar 13<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you or your child are allergic (hypersensitive) to active substances or any of the other ingredients of this medicine (listed in section 6) or any other vaccine containing diphtheria toxoid.<\/li><li>if you or your child have a severe\u00a0infection\u00a0with a high fever (above 38 \u00b0 C).\u00a0If this applies to you or your child, the vaccination will be postponed until you or your child feels better.\u00a0A mild\u00a0infection, such as a cold, should not be a problem but talk to a doctor, pharmacist, or nurse first.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before vaccination if you or your child:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have or have had a health problem after any previous\u00a0dose\u00a0of Prevenar or Prevenar 13 such as an\u00a0allergic reaction\u00a0or breathing problem,<\/li><li>have bleeding problems, or easily getting bruises.<\/li><li>has a weakened immune system (eg due to\u00a0HIV\u00a0infection\u00a0), in which case he\/she may not get the full benefit of Prevenar 13.<\/li><li>had seizures, antipyretic drugs may then need to be given before Prevenar 13 is given.\u00a0If your child has a seizure or becomes absent after vaccination, contact a doctor immediately.\u00a0See also section 4.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before vaccination if your baby is born very prematurely (in or before week 28), as there may be longer breaks between breaths than normal for 2 to 3 days after vaccination.\u00a0See also section 4.<\/p>\n\n\n\n<p>As with all vaccines, Prevenar 13 does not provide full protection to all vaccinated individuals.<\/p>\n\n\n\n<p>Prevenar 13 only protects against ear infections in children caused by the types of the bacterium\u00a0<em>Streptococcus pneumonia<\/em>, for which the vaccine has been developed.\u00a0Prevenar 13 will not protect against other infectious agents that can cause ear infections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines\/vaccines and Prevenar 13<\/h2>\n\n\n\n<p>Your doctor may ask you to give your child&nbsp;paracetamol&nbsp;or any other antipyretic before taking Prevenar 13.&nbsp;This will help reduce any of the possible&nbsp;side effects&nbsp;that may occur with Prevenar 13.<\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you or your child are receiving or have recently received any other medicines, including medicines obtained without a prescription, or have recently been vaccinated with another vaccine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Prevenar 13 has no or negligible effect on the ability to drive and use machines.&nbsp;However, some of the effects mentioned in section 4 \u201cPossible side effects\u201d may temporarily affect the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Prevenar 13 contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per\u00a0dose, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How Prevenar 13 is given<\/h2>\n\n\n\n<p>Your doctor or nurse will inject the recommended\u00a0dose\u00a0(0.5 ml) of the vaccine into a muscle on your upper arm or your baby&#8217;s upper arm or a muscle in your leg.<\/p>\n\n\n\n<p><em><strong>Infants aged 6 weeks to 6 months<\/strong><\/em><\/p>\n\n\n\n<p>Generally, the child should be vaccinated with three&nbsp;doses&nbsp;of the vaccine, followed by a booster dose.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The first\u00a0injection\u00a0can be given from 6 weeks of age.<\/li><li>Each\u00a0injection\u00a0is given at least one month apart.<\/li><li>A fourth\u00a0injection\u00a0(booster dose) is given when the baby is between 11-15 months.<\/li><li>You will be told when the child will return for the next vaccination.<\/li><\/ul>\n\n\n\n<p>By official recommendations in your country, an alternative dosing schedule can be used.\u00a0Talk to a doctor, pharmacist, or nurse for more information.<\/p>\n\n\n\n<p><strong>Premature infants<\/strong><\/p>\n\n\n\n<p>Your child will be initially vaccinated with three&nbsp;doses&nbsp;of the vaccine.&nbsp;The first&nbsp;injection&nbsp;can be given as early as 6 weeks of age and then at least one month apart.&nbsp;Your baby gets a fourth&nbsp;injection&nbsp;(booster) between 11 and 15 months of age.<\/p>\n\n\n\n<p><em>Unvaccinated infants, children, and adolescents over 7 months of age<\/em><\/p>\n\n\n\n<p>Infants aged\u00a0<strong>7 to 11 months<\/strong>\u00a0should receive two\u00a0injections.\u00a0The injections\u00a0are given at least one month apart.\u00a0A third\u00a0injection\u00a0is given during the second year of life.<\/p>\n\n\n\n<p>Children aged\u00a0<strong>12 to 23 months<\/strong>\u00a0should receive two\u00a0injections.\u00a0The injections\u00a0are given at least two months apart.<\/p>\n\n\n\n<p>Children aged\u00a0<strong>2 to 17 years<\/strong>\u00a0should receive an\u00a0injection.<\/p>\n\n\n\n<p><em>Infants, children, and adolescents previously vaccinated with Prevenar<\/em><\/p>\n\n\n\n<p>Infants and children who have previously received Prevenar may receive Prevenar 13 to complete the vaccination program.<\/p>\n\n\n\n<p>For children aged&nbsp;<strong>1-5 years<\/strong>&nbsp;who have previously received Prevenar, your doctor or nurse will recommend how many&nbsp;doses&nbsp;of Prevenar 13 are needed.<\/p>\n\n\n\n<p><em>Children and adolescents aged\u00a0<strong>6-17 years<\/strong>\u00a0should receive an\u00a0injection.<\/em><\/p>\n\n\n\n<p>You must follow the instructions of the doctor, pharmacist, or nurse so that the child undergoes the entire vaccination program.<\/p>\n\n\n\n<p>If you forget to go back in time, ask your doctor, pharmacist, or nurse for advice.<\/p>\n\n\n\n<p><em>Adults<\/em><\/p>\n\n\n\n<p>Adults are given an\u00a0injection.<\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you have previously been vaccinated against\u00a0pneumococci.<\/p>\n\n\n\n<p>If you have any further questions on the use of Prevenar 13, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<p><strong>Special patient groups<\/strong><\/p>\n\n\n\n<p>Individuals who are considered to be at higher risk for pneumococcal infection (eg patients with sickle cell disease or\u00a0HIV infection\u00a0)\u00a0may\u00a0receive at least one\u00a0dose\u00a0of Prevenar 13. This also applies to those previously vaccinated with the 23-valent pneumococcal polysaccharide vaccine.<\/p>\n\n\n\n<p>Individuals who have undergone transplantation of blood-forming\u00a0stem cells\u00a0may receive three\u00a0injections, the first of which is given 3 to 6 months after the transplant at an interval of at least one month between\u00a0doses.\u00a0A fourth\u00a0injection\u00a0(booster) is recommended 6 months after the third\u00a0injection.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all vaccines, Prevenar 13 can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been reported with Prevenar 13 in infants and children (6 weeks to 5 years):<\/strong><\/p>\n\n\n\n<p><strong>The most common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with more than 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite<\/li><li>Fever, irritability, pain, tenderness,\u00a0redness, swelling or hardening at the vaccination site, drowsiness, restless sleep<\/li><li>Redness, hardening, swelling at the vaccination site of 2.5 cm \u2013 7.0 cm (after the booster dose and in older children [aged 2 to 5 years])<\/li><\/ul>\n\n\n\n<p><strong>Common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting, diarrhea<\/li><li>Fever above 39 \u00b0 C, tenderness at the vaccination site affecting mobility,\u00a0redness, hardening, swelling at the vaccination site of 2.5 cm \u2013 7.0 cm (after the basic vaccination)<\/li><li>Rash<\/li><\/ul>\n\n\n\n<p><strong>Uncommon\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 100\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Seizures including seizures caused by high fever<\/li><li>Hives (\u00a0urticaria\u00a0or urticaria-like rash)<\/li><li>Redness, swelling, or hardness at the vaccination site, greater than 7 cm, persistent crying<\/li><\/ul>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 1,000\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Collapse or shock-like state (hypotonic-hyporesponsive episodes)<\/li><li>Allergic (hypersensitivity) reactions, including swelling of the face and\/or lips, difficulty breathing<\/li><\/ul>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been reported with Prevenar 13 in children and adolescents (6 to 17 years of age):<\/strong><\/p>\n\n\n\n<p><strong>The most common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with more than 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite<\/li><li>Irritability, pain, tenderness,\u00a0redness, swelling or hardening at the vaccination site, drowsiness, restless sleep, and tenderness at the vaccination site affect mobility<\/li><\/ul>\n\n\n\n<p><strong>Common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Vomiting, diarrhea<\/li><li>Skin rash, hives (&nbsp;urticaria&nbsp;or urticaria-like rash)<\/li><li>Fever<\/li><\/ul>\n\n\n\n<p>Children and adolescents with either\u00a0HIV\u00a0infection, sickle cell disease, or who have had a blood-forming\u00a0stem cell transplant\u00a0had similar\u00a0side effects, except that headaches, vomiting, diarrhea, fever, fatigue, and joint and muscle pain were very common.<\/p>\n\n\n\n<p>In children who are born very prematurely (born in pregnancy week 28 or earlier), the child may have a longer break than usual between breaths, which can last for 2-3 days after vaccination.<\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been reported with Prevenar 13 in adults:<\/strong><\/p>\n\n\n\n<p><strong>The most common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with more than 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite, headache, diarrhea, vomiting (for people aged 18 to 49 years)<\/li><li>Chills, fatigue, rash, pain,\u00a0redness, swelling, or tenderness at the vaccination site affecting arm mobility (severe pain or tenderness at the vaccination site for persons aged 18 to 39 years and severe reduction of arm mobility for persons aged 18 to 39 years)<\/li><li>Worsening of new-onset pain in joints, worsening or new-onset pain in muscles<\/li><li>Fever (for people aged 18 to 29 years)<\/li><\/ul>\n\n\n\n<p><strong>Common\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 10\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting (for people 50 years and older), fever (for people aged 30 years and older)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon\u00a0side effects\u00a0(which<\/strong>\u00a0may occur with up to 1 in 100\u00a0doses\u00a0of the vaccine) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea<\/li><li>Allergic (hypersensitivity) reactions, including swelling of the face and\/or lips, difficulty breathing<\/li><li>Enlarged\u00a0lymph nodes\u00a0(\u00a0lymphadenopathy\u00a0) in the vicinity of the vaccination site, e.g.\u00a0in armpits<\/li><\/ul>\n\n\n\n<p>Adults with\u00a0HIV\u00a0infection\u00a0had\u00a0similar\u00a0side effects\u00a0except that fever, and vomiting was very common and nausea was common.<\/p>\n\n\n\n<p>Adults undergoing hematopoietic\u00a0stem cell transplantation\u00a0had similar\u00a0side effects\u00a0except that fever and vomiting were very common.<\/p>\n\n\n\n<p><strong>The following additional&nbsp;side effects&nbsp;have been observed with Prevenar 13 after the marketing authorization:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe\u00a0allergic reaction, including\u00a0shock\u00a0(\u00a0cardiovascular\u00a0collapse),\u00a0angioedema\u00a0(swelling of the lips, face, or throat)<\/li><li>Hives (\u00a0urticaria\u00a0),\u00a0redness\u00a0and irritation (skin inflammation) or\u00a0itching\u00a0(\u00a0pruritus\u00a0) at the vaccination site,\u00a0redness<\/li><li>Enlarged\u00a0lymph nodes\u00a0(\u00a0lymphadenopathy\u00a0) in the vicinity of the vaccination site, e.g.\u00a0in the armpits or groin<\/li><li>Skin rash with itchy red spots (erythema multiforme)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Prevenar 13<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/p>\n\n\n\n<p>Do not freeze.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is polysaccharides conjugated to\u00a0carrier protein\u00a0CRM\u00a0<sub>197<\/sub>, consisting of:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>2.2 \u03bcg polysaccharide from serotypes 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19A, 19F and 23F<\/li><li>4.4 \u03bcg polysaccharide from serotype 6B<\/li><\/ul>\n\n\n\n<p>One\u00a0dose\u00a0(0.5 ml) contains approximately 32 \u00b5g of carrier protein CRM\u00a0197,\u00a0adsorbed\u00a0to aluminum phosphate (0.125 mg aluminum).<\/p>\n\n\n\n<p>The other ingredients are sodium chloride, succinic acid, polysorbate 80, and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The vaccine is a white\u00a0suspension\u00a0for\u00a0injection\u00a0and is supplied in a single-dose vial (0.5 ml).\u00a0Pack sizes of 1, 5, 10, 25, and 50 vials.\u00a0Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20150528000045#\" rel=\"noopener\">Show larger<\/a><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Marketing Authorisation Holder:<br>Pfizer Europe MA EEIGBoulevard de la Plaine 171050 BrusselsBelgium<\/td><td>Manufacturer responsible for batch release:<br>Pfizer Manufacturing Belgium NVRijksweg 12B-2870 PuursBelgium<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong><strong>Luxembourg \/ Luxemburg<\/strong>Pfizer NV \/ SATel: + 32 (0) 2 554 62 11<\/td><td><strong>Lithuania<\/strong>Pfizer Luxembourg SARL branches in LithuaniaTel.&nbsp;+ 370 52 51 4000<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Pfizer Emperor Hamburg, Clone of BulgariaTel: +359 2 970 4333<\/td><td><strong>Hungary<\/strong>Pfizer KftTel: +36 1 488 3700<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Pfizer, spol.&nbsp;s roTel: +420 283 004 111<\/td><td><strong>Malta<\/strong>Vivian Corporation Ltd.Tel: +35621 344610<\/td><\/tr><tr><td><strong>Denmark<\/strong>Pfizer ApSTel: + 45 44 201 100<\/td><td><strong>The Netherlands<\/strong>Pfizer BVTel: +31 (0) 10 406 43 01<\/td><\/tr><tr><td><strong>Germany<\/strong>Pfizer Pharma GmbHTel: +49 (0) 30 550055-51000<\/td><td><strong>Norway<\/strong>Pfizer ASTel.&nbsp;+ 47 67 526 100<\/td><\/tr><tr><td><strong>Eesti<\/strong>Pfizer Luxembourg SARL Eesti subsidiaryTel .: +372 666 7500<\/td><td><strong>Austria<\/strong>Pfizer Corporation Austria Ges.mbHTel: +43 (0) 1 521 15-0<\/td><\/tr><tr><td><strong>Greece<\/strong>Pfizer A\u03bb\u03bb\u03ac\u03c2 AE.:\u0397\u03bb .: +30 210 6785 800<\/td><td><strong>Poland<\/strong>Pfizer Polska Sp.&nbsp;z ooTel: +48 22 335 61 00<\/td><\/tr><tr><td><strong>Spain<\/strong>Pfizer, SLTel: +34914909900<\/td><td><strong>Portugal<\/strong>Pfizer Laboratories, Lda.Tel: +351 21 423 5500<\/td><\/tr><tr><td><strong>France<\/strong>PfizerTel: + 33 (0) 1 58 07 34 40<\/td><td><strong>Romania<\/strong>Pfizer Romania SRLTel: + 40 (0) 21 207 28 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pfizer Croatia dooTel: + 385 1 3908 777<\/td><td><strong>Slovenia<\/strong>Pfizer Luxembourg SARLPfizer, underwriting and dryingpharmacevtske dejavnosti, LjubljanaTel .: + 386 (0) 1 52 11 400<\/td><\/tr><tr><td><strong>Ireland<\/strong>Pfizer Healthcare IrelandTel: 1800 633 363 (toll free)+44 (0) 1304 616161<\/td><td><strong>Slovak Republic<\/strong>Pfizer Luxembourg SARL, organizer of services: + 421 2 3355 5500<\/td><\/tr><tr><td><strong>Iceland<\/strong>Icepharma hfPhone: +354 540 8000<\/td><td><strong>Finland \/ Finland<\/strong>Pfizer OyPuh \/ Tel: + 358 (0) 9 430 040<\/td><\/tr><tr><td><strong>Italy<\/strong>Pfizer SrlTel: +39 06 33 18 21<\/td><td><strong>Sweden<\/strong>Pfizer ABTel: +46 (0) 8 550 520 00<\/td><\/tr><tr><td><strong>\u038e\u03c0\u03c1\u03bf\u03c2<\/strong>Pfizer A\u03bb\u03bb\u03ac\u03c2 AE (Cyprus Branch):\u0397\u03bb: +357 22 817690<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Pfizer LimitedTel: +44 (0) 1304 616161<\/td><\/tr><tr><td><strong>Latvia<\/strong>Pfizer Luxembourg SARL subsidiary Latvij\u0101Tel .: + 371 670 35 775<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Polysaccharide vaccine against pneumococcal infections, conjugated, adsorbed , 13-valent<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21466,21842,21462,21465,21838,21841,21463,21839,21464,21840],"class_list":["post-21193","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-polysaccharide-vaccine","tag-benefits-of-prevenar-13","tag-polysaccharide-vaccine","tag-polysaccharide-vaccine-side-effects","tag-prevenar-13","tag-prevenar-13-side-effects","tag-what-is-polysaccharide-vaccine","tag-what-is-prevenar-13","tag-what-polysaccharide-vaccine-is-used-for","tag-what-prevenar-13-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21193"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21193\/revisions"}],"predecessor-version":[{"id":21256,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21193\/revisions\/21256"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}