{"id":21096,"date":"2022-05-09T11:47:21","date_gmt":"2022-05-09T11:47:21","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21096"},"modified":"2022-05-10T10:51:42","modified_gmt":"2022-05-10T10:51:42","slug":"prednisolone-unimedic","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/prednisolone-unimedic\/","title":{"rendered":"Prednisolone Unimedic &#8211; Prednisolone sodium phosphate uses, dose and side effects"},"content":{"rendered":"\n<p>31.25 mg rectal solution<br>Prednisolone sodium phosphate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Prednisolone Unimedic is and what it is used for<\/h2>\n\n\n\n<p>Prednisolone&nbsp;Unimedic is a cortisone preparation used for moderate or severe ulcerative&nbsp;proctosigmoiditis&nbsp;(painful&nbsp;inflammation&nbsp;of the colon), in particular the treatment of acute deterioration of the lower part of the colon or rectum.<\/p>\n\n\n\n<p>Prednisolone sodium phosphate (a type of\u00a0cortisone\u00a0) contained in\u00a0Prednisolone\u00a0Unimedic may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Prednisolone Unimedic<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Prednisolone Unimedic<\/h2>\n\n\n\n<p>&#8211; if you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n<p>if you have a local\u00a0viral, fungal, or bacterial infection (such as\u00a0tuberculosis\u00a0or\u00a0gonorrhea\u00a0).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using\u00a0Prednisolone\u00a0Unimedic.<\/p>\n\n\n\n<p>Contact a doctor if you experience blurred vision or other visual disturbances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Prednisolone Unimedic<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, as\u00a0Prednisolone\u00a0Unimedic may affect the\u00a0dosage\u00a0of one of the medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor or pharmacist if you are taking any of the following:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Medicines (active substance)<\/strong><\/td><td><strong>Purpose of the medicinal product<\/strong><\/td><\/tr><tr><td>phenobarbital,&nbsp;phenytoin&nbsp;and carbamazepine<\/td><td>prevent seizures<\/td><\/tr><tr><td>rifampicin<\/td><td>Treat\u00a0infections\u00a0like\u00a0tuberculosis<\/td><\/tr><tr><td>itraconazole<\/td><td>treat fungal infections<\/td><\/tr><tr><td>ketoconazole (other than\u00a0shampoo\u00a0)<\/td><td>used in Cushing&#8217;s syndrome (when the body produces too much&nbsp;cortisol&nbsp;)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>There is only limited experience with the use of&nbsp;Prednisolone&nbsp;Unimedic during pregnancy.<\/p>\n\n\n\n<p>Prednisolone\u00a0Unimedic passes into breast milk but is unlikely to affect breastfed infants.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Prednisolone Unimedic<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Your doctor will decide which&nbsp;dosage&nbsp;is best for you.<\/p>\n\n\n\n<p>The doctor&#8217;s dosing instructions should always be followed, but the recommended&nbsp;dose&nbsp;in adults is usually 125 ml of rectal solution in the rectum every night before bedtime.<\/p>\n\n\n\n<p><strong>Instructions for use.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Prednisolone\u00a0Unimedic rectal solution is taken at bedtime.\u00a0Use a plastic bag as hand protection (see photos).<\/li><li>Push the protective sleeve down as far as it will go all the way down to the top of the lid (NOTE! Do not turn).<\/li><li>Remove the depressed protective sleeve.<\/li><li>Lie on the left side, possibly with a pillow under the hip, and insert the tip of the bottle into the rectum.\u00a0The insertion can be facilitated if you lubricate the tip with a little Vaseline.<\/li><li>Start by squeezing out a little, so that the intestine gets used to it, and then slowly empty the contents of the bottle into the intestine for a few minutes.<\/li><li>Remove the tip when the bottle is emptied, but keep the bottle still compressed to prevent re-suction.<\/li><li>If you need to pause while using the rectal solution, pull out the spout with the bottle still compressed to prevent re-suction.\u00a0Then continue\u00a0injecting\u00a0the rest of the medicine.\u00a0Discard the bottle after use.<\/li><li>Rollover on your stomach and stay in this position for 3-5 minutes!<\/li><li>The rectal fluid should be kept in the intestine for as long as possible, preferably overnight.<\/li><\/ul>\n\n\n\n<p>Thread the plastic bag over your hand and grab the bottle.&nbsp;Keep the handle around the bottle after it has been emptied.&nbsp;Pull the bag down over the bottle, which is then thrown away.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20151120000068#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/fb40ffa9-c4e5-4e4a-a43d-948167b27215\" alt=\"picture\" title=\"picture\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Prednisolone Unimedic than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Prednisolone Unimedic<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Prednisolone\u00a0Unimedic is given in the rectum.\u00a0When\u00a0prednisolone\u00a0is given in the rectum, the body does not absorb as much\u00a0prednisolone\u00a0and therefore has few\u00a0side effects.\u00a0With long-term use, the levels of certain\u00a0hormones\u00a0that are formed in the\u00a0adrenal cortex\u00a0can decrease (part of the adrenal glands) (plasma cortisol lowering).<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people): Nausea<\/p>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people): Lowering plasma cortisol levels<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users): Blurred vision<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Prednisolone Unimedic<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store in the outer carton to protect from light.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is prednisolone sodium phosphate.\u00a0125 ml rectal solution contains 31.25 mg prednisolone sodium phosphate equivalent to 23.25 mg\u00a0prednisolone<\/li><li>The other ingredients are purified water, sodium chloride,\u00a096%\u00a0ethanol,\u00a0nicotinamide, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), sodium citrate, disodium phosphate dihydrate, sodium hydroxide, and citric acid.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Each package contains 6 soft plastic bottles of 125 ml with an insertion tip and protective sleeve.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Unimedic Pharma AB Box 6216<\/p>\n\n\n\n<p>102 34 Stockholm<\/p>\n\n\n\n<p>Tel: 010-130 99 50<\/p>\n\n\n\n<p>Email: medinfo@unimedicpharma.se<\/p>\n\n\n\n<p><em>Manufacturer<\/em>&nbsp;:<\/p>\n\n\n\n<p>Unimedic AB<\/p>\n\n\n\n<p>Box 91<\/p>\n\n\n\n<p>864 21 Matfors<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prednisolone Unimedic is a cortisone preparation used for moderate or severe ulcerative proctosigmoiditis (painful inflammation of the colon), in particular the treatment of acute deterioration of the lower part of the colon or rectum.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21613,21618,21609,21612,21614,21617,21610,21615,21611,21616],"class_list":["post-21096","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-prednisolone-sodium-phosphate","tag-benefits-of-prednisolone-unimedic","tag-prednisolone-sodium-phosphate","tag-prednisolone-sodium-phosphate-side-effects","tag-prednisolone-unimedic","tag-prednisolone-unimedic-side-effects","tag-what-is-prednisolone-sodium-phosphate","tag-what-is-prednisolone-unimedic","tag-what-prednisolone-sodium-phosphate-is-used-for","tag-what-prednisolone-unimedic-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21096","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21096"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21096\/revisions"}],"predecessor-version":[{"id":21124,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21096\/revisions\/21124"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21096"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21096"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21096"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}