{"id":21074,"date":"2022-05-09T11:04:18","date_gmt":"2022-05-09T11:04:18","guid":{"rendered":"https:\/\/zeepedia.com\/?p=21074"},"modified":"2022-05-10T11:03:25","modified_gmt":"2022-05-10T11:03:25","slug":"pravastatin-rivopharm","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pravastatin-rivopharm\/","title":{"rendered":"Pravastatin Rivopharm &#8211; Pravastatin sodium uses, dose and side effects"},"content":{"rendered":"\n<p>20 mg and 40 mg&nbsp;tablets<br>(pravastatin sodium)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pravastatin Rivopharm is and what it is used for<\/h2>\n\n\n\n<p>The active substance in this medicine is pravastatin sodium, which belongs to a group of medicines called statins or &#8216;HMG-CoA reductase inhibitors&#8217;.\u00a0These drugs work by reducing the levels of\u00a0cholesterol\u00a0and other fats, called\u00a0triglycerides, in the blood.<\/p>\n\n\n\n<p>Cholesterol&nbsp;is important for the body to function, but if the cholesterol level is too high (&nbsp;hypercholesterolemia&nbsp;), it can accumulate on the artery walls and lead to the blood vessels clogging.&nbsp;This in turn can cause angina (severe chest pain) and heart attack.<\/p>\n\n\n\n<p>High cholesterol in the blood can be due to many factors, including high cholesterol and fatty diets, certain diseases, hereditary diseases, and too little exercise.<\/p>\n\n\n\n<p>Your doctor may have prescribed Pravastatin Rivopharm tablets as a supplement to your diet for any of the following reasons:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have high levels of\u00a0cholesterol\u00a0or fats in your blood, which have not dropped after measures in the form of diet, weight loss, or exercise.<\/li><li>You have coronary heart disease or you are at risk of developing coronary heart disease because you have\u00a0diabetes, have had a\u00a0stroke, or other vascular disease or chest pain (\u00a0unstable angina\u00a0pectoris).\u00a0Pravastatin sodium can reduce the risk of heart disease and thereby prolong life by helping to keep your\u00a0arteries\u00a0open, even if you have normal cholesterol levels.<\/li><li>You have high cholesterol and are taking medication to prevent your body from rejecting a newly transplanted organ.<\/li><\/ul>\n\n\n\n<p>Your doctor will also advise you on how to lower your blood cholesterol levels by eating a low-fat diet throughout your treatment with Pravastatin Rivopharm tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Pravastatin Rivopharm<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pravastatin Rivopharm<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to pravastatin sodium or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are pregnant or planning to become pregnant<\/li><li>if you are breast-feeding<\/li><li>if you have liver problems<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Pravastatin Rivopharm in some patients may increase the risk of\u00a0myopathy, which causes muscle aches, sore muscles, and decreased muscle strength.\u00a0Your doctor may take blood samples to check the condition of your muscles before and after you start treatment with Pravastatin Rivopharm.<\/p>\n\n\n\n<p>Talk to your doctor BEFORE you take the tablets if any of the following apply to you as you may be at greater risk of developing\u00a0myopathy.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you get unexplained muscle aches, sore muscles,<\/strong> or decreased muscle strength, or if you have ever had a disease called\u00a0myopathy\u00a0(muscle disease).<\/li><li>If you have ever had muscle problems during treatment with cholesterol-lowering medicines called statins (eg\u00a0simvastatin\u00a0or atorvastatin) or fibrates (eg gemfibrozil and fenofibrate).If you are taking, or within the last 7 days, have taken or been given a medicine called fusidic acid (a medicine for bacterial\u00a0infections\u00a0) by mouth or by\u00a0injection.\u00a0The combination of fusidic acid and Pravastatin Rivopharm can lead to severe muscle problems (\u00a0rhabdomyolysis\u00a0).<\/li><li>If you drink a lot of alcohol or have had liver disease.\u00a0Your doctor may take some blood samples to examine your liver before and after starting treatment.<\/li><li>If you or close family members have a hereditary muscle disease.<\/li><li>If you have kidney or thyroid problems.<\/li><li>If you are over 70 years old.<\/li><li>If you have had liver disease.<\/li><\/ul>\n\n\n\n<p><strong>Ask your doctor or pharmacist for advice before taking Pravastatin Rivopharm if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have a severe pulmonary impairment.<\/li><\/ul>\n\n\n\n<p>During treatment with this medicine, your doctor will closely monitor you if you have\u00a0diabetes\u00a0or are at risk of developing\u00a0diabetes.\u00a0You are more likely to get\u00a0diabetes\u00a0if you have high blood sugar and high blood fat levels, are overweight and have high\u00a0blood pressure.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you have persistent muscle weakness.&nbsp;Additional tests and medications may be needed to investigate and treat this.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pravastatin Rivopharm<\/h2>\n\n\n\n<p><strong>The risk of muscle problems may increase if Pravastatin Rivopharm is taken with other medicines.\u00a0Tell your doctor if you are taking, have recently taken, or might take any of the following medicines:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are taking medicines called fibrates, e.g.\u00a0gemfibrozil or fenofibrate (cholesterol-lowering drugs).<\/li><li>If you need to take fusidic acid by mouth to treat a bacterial infection, you must temporarily stop using this medicine.\u00a0Your doctor will tell you when it is safe to start taking Pravastatin Rivopharm again.\u00a0Pravastatin Rivopharm taken with fusidic acid may in rare cases lead to muscle weakness, tenderness, or pain (\u00a0rhabdomyolysis\u00a0).\u00a0For more information on\u00a0rhabdomyolysis, see section 4.<\/li><\/ul>\n\n\n\n<p>Other medicines can be affected by Pravastatin Rivopharm.&nbsp;They in turn can affect the way pravastatin sodium works.&nbsp;Tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drugs used to\u00a0inhibit\u00a0the immune system, e.g.\u00a0cyclosporine.<\/li><li>Niacin\u00a0or\u00a0nicotinic acid\u00a0in\u00a0doses\u00a0higher than or equal to 1 g per day (used as a cholesterol-lowering drug).<\/li><li>Drugs that contain cholestyramine or colestipol (often used as cholesterol-lowering drugs).<\/li><li>Antibiotics\u00a0such as erythromycin or clarithromycin.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before taking Pravastatin Rivopharm if you are taking a medicine that is used to treat and prevent the formation of blood clots, a so-called &#8220;vitamin K antagonist&#8221;, as the use of\u00a0vitamin\u00a0K\u00a0antagonist\u00a0together with pravastatin Rivopharm may affect the results. of blood samples used to monitor treatment with\u00a0vitamin\u00a0K\u00a0antagonist\u00a0er.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pravastatin Rivopharm with food and drink<\/h2>\n\n\n\n<p>Pravastatin Rivopharm tablets can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0If you become pregnant while taking Pravastatin Rivopharm, stop taking them immediately and consult a doctor.<\/p>\n\n\n\n<p>Do not take Pravastatin Rivopharm if you are breastfeeding as this medicine passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>This medicine may make you dizzy.&nbsp;If this happens, do not drive or use machines until you feel better.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pravastatin Rivopharm contains lactose<\/h2>\n\n\n\n<p>This medicine contains\u00a0lactose.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Pravastatin Rivopharm.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pravastatin Rivopharm<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Pravastatin Rivopharm tablets should be taken as a single dose in the evening or at night.&nbsp;Swallow the tablets whole with a glass of water.&nbsp;The recommended&nbsp;dose&nbsp;is:<\/p>\n\n\n\n<p><strong>Adults (18 years and older):<\/strong><\/p>\n\n\n\n<p>The recommended starting dose for lowering cholesterol is 10 mg once a day.&nbsp;Your doctor may increase this&nbsp;dose&nbsp;to 40 mg once a day.<\/p>\n\n\n\n<p>The starting and maintenance dose for the prevention of coronary heart disease is 40 mg.<\/p>\n\n\n\n<p>The starting dose after organ transplantation is 20mg once a day.&nbsp;Your doctor may increase the&nbsp;dose&nbsp;from one to 40 mg.<\/p>\n\n\n\n<p>The starting dose for patients with moderate or severe kidney disease or significant liver problems is 10 mg daily.&nbsp;Your doctor may change your&nbsp;dose&nbsp;depending on how you react to the treatment.<\/p>\n\n\n\n<p><strong>Use in children and adolescents, 8\u201313 years:<\/strong><\/p>\n\n\n\n<p>The recommended starting dose for lowering cholesterol is 10 mg once a day.&nbsp;Your doctor may increase this&nbsp;dose&nbsp;to 20 mg once a day.<\/p>\n\n\n\n<p><strong>Young people 14\u201318 years:<\/strong><\/p>\n\n\n\n<p>The recommended starting dose for lowering cholesterol is 10 mg once a day.&nbsp;Your doctor may increase this&nbsp;dose&nbsp;to 40 mg once a day.<\/p>\n\n\n\n<p>If you are taking a medicine that contains cholestyramine or colestipol (to lower your cholesterol), Pravastatin Rivopharm tablets should be taken at least one hour before or four hours after you have taken such medicines.&nbsp;The reason for this is that these drugs can affect the&nbsp;absorption&nbsp;of pravastatin if taken too close to each other.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Pravastatin Rivopharm than you should<\/h2>\n\n\n\n<p>If you take more Pravastatin Rivopharm than you should, or if you accidentally swallow any tablets, contact your doctor or pharmacist as soon as possible or go to the nearest emergency room immediately.&nbsp;Remember to bring the pack and any remaining tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Pravastatin Rivopharm<\/h2>\n\n\n\n<p>If you forget to take Pravastatin Rivopharm tablet (s), do not worry.\u00a0Only take the next\u00a0dose\u00a0when it is time for it.\u00a0Do not take a double\u00a0dose\u00a0to make up for a\u00a0forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Pravastatin Rivopharm<\/h2>\n\n\n\n<p>If you stop taking Pravastatin Rivopharm tablets, your cholesterol level may rise again.&nbsp;Keep taking the tablets for as long as your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>If any of these serious\u00a0side effects\u00a0occur, stop taking this medicine and contact your doctor immediately or go to the nearest emergency department.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle aches, decreased muscle strength, sore muscles or muscle aches, and especially if you also feel sick or have a fever.\u00a0In very rare cases, muscle problems can be serious (\u00a0rhabdomyolysis\u00a0) and can lead to serious, life-threatening kidney disease.<\/li><li>Sudden severe allergic reactions include sudden wheezing, difficulty breathing, swollen eyelids, lips, tongue or throat, skin rash or\u00a0itching\u00a0(especially if the whole body is affected), joint pain,\u00a0inflammation\u00a0of joints and blood vessels, abnormal bruising, rash, swelling, hives, skin becomes sensitive to sunlight if you get a fever or hot flashes.<\/li><li>Inflammation\u00a0of the liver with yellowing of the skin and whites of the eyes,\u00a0itching, dark-colored urine, or pale-colored stools (liver failure).<\/li><li>Inflammation\u00a0of the pancreas often with severe abdominal pain.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported with pravastatin:<\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>headache<\/li><li>difficulty sleeping<\/li><li>sleep disorders (insomnia)<\/li><li>visual disturbances, such as blurred vision or double vision<\/li><li>stomach upset (such as nausea or vomiting, constipation, diarrhea, flatulence, indigestion, and stomach pain)<\/li><li>hair loss<\/li><li>rash<\/li><li>itching<\/li><li>impotence<\/li><li>fatigue<\/li><li>impotence<\/li><li>the way your liver works<\/li><li>heartburn<\/li><li>bladder problems (painful or dense bladder emptying)<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects up to 1 in 10,000 people, including occasional reports)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>numbness or loss of sensation in the arms and legs<\/li><li>crawling or tingling (&nbsp;paresthesia&nbsp;)<\/li><li>muscle and joint pain<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Persistent muscle weakness.<\/li><\/ul>\n\n\n\n<p>Other possible&nbsp;side effects&nbsp;that have been reported with certain statins are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sleep disorders including insomnia and nightmares<\/li><li>Memory loss<\/li><li>Impaired sexual ability<\/li><li>Depression<\/li><li>Respiratory problems including persistent cough and\/or shortness of breath or fever<\/li><li>Diabetes\u00a0Mellitus: The frequency depends on the presence or absence of risk factors (fasting glucose \u22655.6 mmol \/ l,\u00a0BMI\u00a0> 30 kg \/ m\u00a02, elevated\u00a0triglycerides, high\u00a0blood pressure\u00a0in the history of the disease).<\/li><li>Dermatomyositis\u00a0(a condition characterized by an\u00a0inflammation\u00a0of the muscles and skin).<\/li><\/ul>\n\n\n\n<p><strong>Reporting of\u00a0side effects\u00a0If<br><\/strong>If you get\u00a0any side effects, talk to your doctor, pharmacist, or nurse.\u00a0This also applies to side effects that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly via the Medical Products Agency, Box 26, SE-751 03 Uppsala.\u00a0Website: www.lakemedelsverket.se.\u00a0By reporting\u00a0side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pravastatin Rivopharm<\/h2>\n\n\n\n<p><strong>Keep this medicine out of the sight and reach of children.<\/strong><\/p>\n\n\n\n<p>Pravastatin Rivopharm tablets should not be stored above 25 \u00b0 C.&nbsp;Close the package tightly.&nbsp;Store in the original package<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and each blister pack of tablets.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is pravastatin sodium.<\/p>\n\n\n\n<p>Each tablet contains 20 mg or 40 mg of pravastatin sodium.<\/p>\n\n\n\n<p>The other ingredients are\u00a0lactose monohydrate, microcrystalline cellulose, magnesium aluminum silicate, croscarmellose sodium, povidone, talc, and magnesium stearate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pravastatin Rivopharm 20 mg tablets are white to off-white capsule-shaped tablets marked with \u201c6\u201d on one side of the tablet and \u201cPV 20\u201d on the other side.\u00a0The breaking slot allows the tablet to be divided into two equal\u00a0doses.<\/p>\n\n\n\n<p>Pravastatin Rivopharm 40 mg tablets are white to off-white capsule-shaped tablets marked with \u201c6\u201d on one side of the tablet and \u201cPV 40\u201d on the other side.<\/p>\n\n\n\n<p>Pravastatin Rivopharm 20 mg tablets are available in blister packs of 10, 20, 28, 30, 50, 56, 60, 98, 100 and 500 (5&#215;100) tablets and jars of 30, 250 and 1000 tablets.<\/p>\n\n\n\n<p>Pravastatin Rivopharm 40 mg tablets are available in blister packs of 10, 14, 20, 28, 30, 50, 56, 60, 98, 100 and 500 (5&#215;100) tablets and jars of 30, 250 and 750 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Rivopharm Ltd.<\/p>\n\n\n\n<p>17 Corrig Road<\/p>\n\n\n\n<p>Sandyford, Dublin 18<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>\u2022 Arrow Pharm (Malta) Ltd, HF 62, Hal Far Industrial Estate, Birzebbugia BBG 06, Malta<\/p>\n\n\n\n<p>\u2022 Juta Pharma GmbH, Gutenbergstrasse 13, 24941 Flensburg, Germany<\/p>\n\n\n\n<p>\u2022 Quality (Burnley) Limited, Talbot Street, Briercliffe, Burnley, Lancashire, BB10 2JY<\/p>\n\n\n\n<p>UK<\/p>\n\n\n\n<p>\u2022 Actavis Ltd, BLB 016, Bulebel Industrial Estate, Zejtun, ZTN 3000, Malta<\/p>\n\n\n\n<p><strong>Agent:<\/strong><\/p>\n\n\n\n<p>SanoSwiss UAB<\/p>\n\n\n\n<p>Love 25-701<\/p>\n\n\n\n<p>LT-09320 Vilnius<\/p>\n\n\n\n<p>Lithuania<\/p>\n\n\n\n<p>info@sanoswiss.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The active substance in this medicine is pravastatin sodium, which belongs to a group of medicines called statins or &#8216;HMG-CoA reductase inhibitors&#8217;. These drugs work by reducing the levels of cholesterol and other fats, called triglycerides , in the blood.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21687,21688,21692,21691,21677,21681,21689,21678,21690,21679],"class_list":["post-21074","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pravastatin-sodium","tag-pravastatin-rivopharm","tag-pravastatin-rivopharm-side-effects","tag-pravastatin-rivopharm-tablet","tag-pravastatin-sodium","tag-pravastatin-sodium-side-effects","tag-what-is-pravastatin-rivopharm","tag-what-is-pravastatin-sodium","tag-what-pravastatin-rivopharm-is-used-for","tag-what-pravastatin-sodium-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=21074"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21074\/revisions"}],"predecessor-version":[{"id":21137,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/21074\/revisions\/21137"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=21074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=21074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=21074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}