2 g \/ 0.25 g and 4 g \/ 0.5 g powder for solution for infusion piperacillin
\/ tazobactam<\/p>\n\n\n\n
Piperacillin belongs to a group of medicines called ‘broad-spectrum penicillin antibiotics’. It can kill many types of bacteria. Tazobactam may prevent certain resistant bacteria from surviving the effects of piperacillin. This means that several types of bacteria are killed when piperacillin and tazobactam are given together.<\/p>\n\n\n\n
Piperacillin \/ Tazobactam Fresenius Kabi is used in adults and adolescents to treat bacterial infections such as those affecting the lower respiratory tract (lungs), urinary tract (kidneys and bladder), abdomen, skin, or blood.
Piperacillin \/ Tazobactam Fresenius Kabi can be used to treat bacterial infections in patients with low\u00a0white blood cell count\u00a0(reduced resistance to\u00a0infections\u00a0).<\/p>\n\n\n\n
Piperacillin \/ Tazobactam Fresenius Kabi is used in children aged 2-12 years to treat\u00a0infections\u00a0in the abdomen, such as appendicitis,\u00a0peritonitis\u00a0(\u00a0infection\u00a0of the fluid and the lining of the abdominal organs), and\u00a0infection\u00a0of the gallbladder.
Piperacillin \/ Tazobactam Fresenius Kabi can be used to treat bacterial infections in patients with low\u00a0white blood cell count\u00a0(reduced resistance to\u00a0infections\u00a0).<\/p>\n\n\n\n
In case of some serious\u00a0infection, your doctor may consider using Piperacillin \/ Tazobactam Fresenius Kabi in combination with other\u00a0antibiotics.<\/p>\n\n\n\n
Piperacillin\/tazobactam contained in Piperacillin \/ Tazobactam Fresenius Kabi may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor or another healthcare professional if you have any further questions and always follow their instructions.<\/p>\n\n\n\n
Talk to your doctor or nurse before using Piperacillin \/ Tazobactam Fresenius Kabi:<\/p>\n\n\n\n
Hemophagocytic lymphohistiocytosis<\/strong><\/p>\n\n\n\n There have been reports of a disease in which the immune system produces too many of the otherwise normal\u00a0white blood cells, so-called histiocytes, and\u00a0lymphocytes, which leads to\u00a0inflammation\u00a0(hemophagocytic lymphohistiocytosis).\u00a0This condition can be life-threatening if not diagnosed and treated early.\u00a0If you get several symptoms, e.g.\u00a0fever, swollen\u00a0glands, feeling weak, feeling dizzy, shortness of breath, bruising, or rash, you should contact your doctor immediately.<\/p>\n\n\n\n The use of piperacillin\/tazobactam is not recommended for use in children below 2 years of age due to insufficient data on safety and efficacy.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0Some medicines may affect or be affected by piperacillin and tazobactam. Effects on laboratory tests<\/strong> If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0Your doctor will decide if Piperacillin \/ Tazobactam Fresenius Kabi is right for you.<\/p>\n\n\n\n Piperacillin and tazobactam can pass into a fetus or be excreted in human milk.\u00a0If you are breastfeeding, your doctor will decide if Piperacillin \/ Tazobactam Fresenius Kabi is right for you.<\/p>\n\n\n\n The use of Piperacillin \/ Tazobactam Fresenius Kabi is not expected to affect the ability to drive or use machines.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n Piperacillin \/ Tazobactam Fresenius Kabi 2 g \/ 0.25 g <\/strong> contains<\/strong> 112 mg sodium (the main ingredient in table salt \/ table salt) per vial . This corresponds to 5.6% of the maximum recommended daily intake of sodium for adults.<\/p>\n\n\n\n Piperacillin \/ Tazobactam Fresenius Kabi 4 g \/ 0.5 g <\/strong>contains<\/strong> <\/p>\n\n\n\n 224 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per\u00a0vial.\u00a0This corresponds to 11.2% of the highest recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n Your doctor or other healthcare professional will give you this medicine by infusion (a 30-minute drip) into one of your veins.<\/p>\n\n\n\n The dose of medicine you are given depends on what you are being treated for, your age, and whether you have kidney problems or not.<\/p>\n\n\n\n Adults and adolescents 12 years of age and older<\/em><\/strong> Children 2 to 12 years of age<\/em><\/strong><\/p>\n\n\n\n The recommended\u00a0dose\u00a0for children with abdominal infections is 100 mg \/ 12.5 mg piperacillin\/tazobactam per kg body weight given every 8 hours in a vein (directly in the bloodstream).\u00a0The usual\u00a0dose\u00a0for children with low\u00a0white blood cell count\u00a0is 80 mg \/ 10 mg piperacillin\/tazobactam per kg body weight given every 6 hours in a vein (directly in the bloodstream).<\/p>\n\n\n\n Your doctor will calculate a\u00a0dose\u00a0depending on your child’s body weight, but each dose\u00a0should not exceed 4 g \/ 0.5 g piperacillin\/tazobactam.<\/p>\n\n\n\n You will be given Piperacillin \/ Tazobactam Fresenius Kabi until the signs of infection have completely disappeared (5 to 14 days).<\/p>\n\n\n\n Patients with kidney problems Your<\/em><\/strong> Because you are being given Piperacillin \/ Tazobactam Fresenius Kabi by a doctor or other healthcare professional, it is unlikely that you will be given the wrong\u00a0dose.\u00a0However, if you experience\u00a0side effects\u00a0such as seizures or if you think you have had too much, tell your doctor immediately.<\/p>\n\n\n\n If you think you have not received a\u00a0dose of\u00a0Piperacillin \/ Tazobactam Fresenius Kabi tell your doctor or another healthcare professional immediately.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Talk to your doctor immediately<\/strong>\u00a0if you experience any of these potentially serious\u00a0side effects\u00a0from Piperacillin \/ Tazobactam Fresenius Kabi:<\/p>\n\n\n\n Serious adverse reactions (in brackets) from Piperacillin \/ Tazobactam Fresenius Kabi are:<\/strong><\/p>\n\n\n\n If any of the\u00a0following\u00a0<\/strong>side effects\u00a0get worse or if you notice any\u00a0side effects\u00a0not listed in this leaflet, please tell your doctor or healthcare professional.<\/p>\n\n\n\n Very common side effects (affects more than 1 user in 10):<\/strong><\/p>\n\n\n\n Common side effects (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n Uncommon side effects (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n Rare side effects (may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n Has been reported (occurs in an unknown number of people) <\/strong>:<\/strong><\/p>\n\n\n\n Treatment with piperacillin has been associated with an increased incidence of fever and rash in patients with\u00a0cystic fibrosis.<\/p>\n\n\n\n Beta-lactam antibiotics, including piperacillin\/tazobactam, may lead to the\u00a0manifestation\u00a0of\u00a0encephalopathy\u00a0(brain damage or brain disease) and convulsions<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Store the vials in the outer carton.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton after \u201cEXP\u201d. and on the vial after \u201cEXP\u201d.<\/p>\n\n\n\n The expiration date is the last day of the specified month.<\/p>\n\n\n\n Unopened vials: Do not store above 25 \u00b0 C.<\/p>\n\n\n\n For single use only. Discard any unused solution.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substances are piperacillin and tazobactam.<\/p>\n\n\n\n Each vial contains 2 g piperacillin (as sodium salt) and 0.25 g tazobactam (as sodium salt). The product does not contain any other substances.<\/p>\n\n\n\n Piperacillin \/ Tazobactam Fresenius Kabi 2 g \/ 0.25 g and 4 g \/ 0.5 g are a white to off-white lyophilized powder for\u00a0solution for\u00a0infusion Not all sizes may be marketed.<\/p>\n\n\n\n Manufacturer:<\/strong><\/p>\n\n\n\n LABESFAL – Laborat\u00f3rios Almiro SA and<\/p>\n\n\n\n For Piperacillin \/ Tazobactam Fresenius Kabi 4 g \/ 0.5 g:<\/p>\n\n\n\n MITIM Srl<\/p>\n\n\n\n Via Cacciamali no 34-36-38<\/p>\n\n\n\n 25125 Brescia<\/p>\n\n\n\n Italy<\/p>\n","protected":false},"excerpt":{"rendered":" Piperacillin belongs to a group of medicines called ‘broad-spectrum penicillin antibiotics’. It can kill many types of bacteria. Tazobactam may prevent certain resistant bacteria from surviving the effects of piperacillin. This means that several types of bacteria are killed when piperacillin and tazobactam are given together.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21385,21362,21365,21371,21386,21389,21363,21372,21387,21364,21388,21373],"class_list":["post-20880","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-piperacillin","tag-piperacillin","tag-piperacillin-side-effects","tag-tazobactam","tag-tazobactam-fresenius-kabi","tag-tazobactam-fresenius-kabi-side-effects","tag-what-is-piperacillin","tag-what-is-tazobactam","tag-what-is-tazobactam-fresenius-kabi","tag-what-piperacillin-is-used-for","tag-what-tazobactam-fresenius-kabi-is-used-for","tag-what-tazobactam-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20880"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20880\/revisions"}],"predecessor-version":[{"id":20927,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20880\/revisions\/20927"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Children under 2 years<\/h2>\n\n\n\n
Other medicines and Piperacillin \/ Tazobactam Fresenius Kabi<\/h2>\n\n\n\n
These include:<\/p>\n\n\n\n
Tell your doctor or laboratory staff that you are taking Piperacillin \/ Tazobactam Fresenius Kabi if you have to take a blood or urine sample.<\/p>\n\n\n\nPregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Piperacillin \/ Tazobactam Fresenius Kabi contains sodium<\/h2>\n\n\n\n
How to use Piperacillin \/ Tazobactam Fresenius Kabi<\/h2>\n\n\n\n
The recommended\u00a0dose\u00a0is 4 g \/ 0.5 g piperacillin\/tazobactam given every 6 to 8 hours as\u00a0an infusion\u00a0into one of your veins (directly into the bloodstream).<\/p>\n\n\n\n
the doctor may need to reduce the\u00a0dose\u00a0of Piperacillin \/ Tazobactam Fresenius Kabi or how often you get it.\u00a0Your doctor may also want to test your blood to ensure that the treatment is given at the right\u00a0dose, especially if you have to take the medicine for a long time.<\/p>\n\n\n\nIf you take more Piperacillin \/ Tazobactam Fresenius Kabi than you should<\/h2>\n\n\n\n
If you forget to take a dose of Piperacillin \/ Tazobactam Fresenius Kabi<\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
How to store Piperacillin \/ Tazobactam Fresenius Kabi<\/h2>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Each vial contains 4 g of piperacillin (as sodium salt) and 0.5 g of tazobactam (as sodium salt).<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Piperacillin \/ Tazobactam Fresenius Kabi 2 g \/ 0.25 g are available in 15 ml and 50 g ml vials of stained glass (type II) closed with a gray chlorobutyl rubber stopper.
Piperacillin \/ Tazobactam Fresenius Kabi 4 g \/ 0.5 g are available in 50 ml stained glass vials (type II) closed with a gray chlorobutyl rubber stopper.
Pack sizes: 1, 5, and 10 vials.<\/p>\n\n\n\nMarketing Authorisation Holder:<\/h2>\n\n\n\n
Fresenius Kabi AB, SE-751 74 Uppsala, Sweden<\/p>\n\n\n\n
FRESENIUS KABI GROUP
3465-157 Santiago de Besteiros
Portugal<\/p>\n\n\n\n