{"id":20878,"date":"2022-04-15T15:43:43","date_gmt":"2022-04-15T15:43:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20878"},"modified":"2022-04-18T17:06:16","modified_gmt":"2022-04-18T17:06:16","slug":"pioglitazone-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pioglitazone-actavis\/","title":{"rendered":"Pioglitazone Actavis &#8211; Pioglitazone uses, dose and side effects"},"content":{"rendered":"\n<p>15 mg, 30 mg, 45 mg&nbsp;tablets<br>pioglitazone (pioglitazone)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pioglitazone Actavis is and what it is used for<\/h2>\n\n\n\n<p>Pioglitazone Actavis contains pioglitazone.\u00a0It is an antidiabetic medicine\u00a0used to treat type 2\u00a0diabetes\u00a0mellitus\u00a0when\u00a0metformin\u00a0is not suitable or has sufficient effect.\u00a0This type of\u00a0diabetes\u00a0is also called &#8220;non-insulin-dependent&#8221; and usually occurs in adulthood.<\/p>\n\n\n\n<p>Pioglitazone Actavis helps keep blood sugar levels under control in type 2&nbsp;diabetes&nbsp;so that the body can make better use of the&nbsp;insulin&nbsp;that is produced.&nbsp;3 to 6 months after starting treatment, your doctor will check if Pioglitazone Actavis is working for you.<\/p>\n\n\n\n<p>Pioglitazone Actavis can be used only in patients who can not take\u00a0metformin\u00a0and when treatment with diet and exercise fails to control blood sugar levels or can be added to other treatments (such as\u00a0metformin, sulphonylureas, or\u00a0insulin\u00a0) that have failed to control blood sugar levels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Pioglitazone Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Pioglitazone Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to pioglitazone or any of the other ingredients of Pioglitazone Actavis (see section 6 Contents).<\/li><li>if you have or have had\u00a0heart failure\u00a0in the past.<\/li><li>if you have liver disease.<\/li><li>if you have had diabetic\u00a0ketoacidosis\u00a0(a complication of\u00a0diabetes\u00a0that causes rapid weight loss, nausea, or vomiting<\/li><li>if you have or have ever had bladder cancer<\/li><li>if you have blood in your urine that your doctor has not examined further<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking this medicine:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are accumulating water (\u00a0fluid retention\u00a0) or have problems with\u00a0heart failure, especially if you are over 75 years old.\u00a0Tell your doctor if you are taking anti-inflammatory medications that may cause you to accumulate fluid and swell.<\/li><li>if you have a type of diabetes-related eye disease called macular edema (swelling in the back of the eye).<\/li><li>if you have ovarian cysts (\u00a0polycystic ovary syndrome\u00a0).\u00a0There may be an increased chance of getting pregnant because you may ovulate again when you take Pioglitazone Actavis.\u00a0If this affects you, use appropriate contraception to avoid unplanned pregnancy.<\/li><li>if you have liver or heart problems.\u00a0Before you start using Pioglitazone Actavis, you will need to have a blood test to check your liver function.\u00a0This check may be repeated at intervals.\u00a0Some patients who have had type 2\u00a0diabetes mellitus\u00a0and heart disease for many years or previous\u00a0strokes\u00a0developed\u00a0heart failure\u00a0during treatment with Pioglitazone Actavis and\u00a0insulin.\u00a0Tell your doctor as soon as possible if you get signs of\u00a0heart failure\u00a0such as unexpected shortness of breath, rapid weight gain, or local swelling (\u00a0edema\u00a0).<\/li><\/ul>\n\n\n\n<p>If you use Pioglitazone Actavis with other diabetes medicines, your blood sugar may likely drop below normal levels (hypoglycemia).<\/p>\n\n\n\n<p>You may also have a decrease in the number of&nbsp;blood cells&nbsp;(&nbsp;anemia&nbsp;).<\/p>\n\n\n\n<p><strong>Fracture<\/strong><\/p>\n\n\n\n<p>A higher incidence of bone fractures has been observed in patients, especially in women taking pioglitazone.\u00a0Your doctor will take this into account when treating your\u00a0diabetes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Use in children under 18 years of age is not recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pioglitazone Actavis<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>You can normally continue to take other medicines while you are being treated with Pioglitazone Actavis.&nbsp;However, some drugs are especially likely to affect the amount of sugar in your blood:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gemfibrozil (cholesterol lowering)<\/li><li>Rifampicin (used to treat tuberculosis and other&nbsp;infections&nbsp;)<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking any of these preparations.&nbsp;Your blood sugar will be monitored and your&nbsp;dose&nbsp;of Pioglitazone Actavis may need to be adjusted.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pioglitazone Actavis with food and drink<\/h2>\n\n\n\n<p>The tablets can be taken with or without food.&nbsp;The tablets should be swallowed together with a glass of water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.<\/p>\n\n\n\n<p>Your doctor will advise you to stop taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Pioglitazone does not affect your ability to drive or use machines, but use caution if you experience visual disturbances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pioglitazone Actavis contains lactose monohydrate<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Pioglitazone Actavis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Pioglitazone Actavis<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The usual starting dose is a 15 mg or 30 mg pioglitazone tablet taken once daily.&nbsp;Your doctor may increase your&nbsp;dose&nbsp;to a maximum of 45 mg once a day.&nbsp;Your doctor will tell you which&nbsp;dose&nbsp;to take.&nbsp;If you have the impression that the effect of Pioglitazone Actavis is too weak, talk to your doctor.<\/p>\n\n\n\n<p>Pioglitazone Actavis can be taken with or without food.<\/p>\n\n\n\n<p>When Pioglitazone Actavis is taken in combination with other medicines used to treat\u00a0diabetes\u00a0(such as\u00a0insulin, chloropropamide, glibenclamide, gliclazide, tolbutamide), your doctor will tell you if you need to take a smaller dose of any of your medicines.<\/p>\n\n\n\n<p>Your doctor will take blood tests regularly during treatment with Pioglitazone Actavis.&nbsp;This is done to check that the liver is functioning normally.<\/p>\n\n\n\n<p>If you have been recommended for a diabetic diet, you should continue with this while you are taking Pioglitazone Actavis.<\/p>\n\n\n\n<p>Check your weight regularly and tell your doctor if the weight increases.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Pioglitazone Actavis than you should<\/h2>\n\n\n\n<p>If you accidentally take too many tablets, or if someone else or a child takes your medicine, talk to a doctor or pharmacist immediately.\u00a0Your blood sugar can drop below normal levels and can be increased by consuming sugar.\u00a0It is recommended to carry sugar cubes, sweets, biscuits, or sugary fruit drinks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Pioglitazone Actavis<\/h2>\n\n\n\n<p>Try to take Pioglitazone Actavis daily as prescribed.\u00a0However, if you miss a\u00a0dose, just continue with the next\u00a0dose\u00a0as usual.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten tablet.<\/p>\n\n\n\n<p>For pack sizes of 14, 28, 56, 84, and 98 tablets, you can see which day you last took a Pioglitazone Actavis tablet using the calendar printed on the blister card.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Pioglitazone Actavis<\/h2>\n\n\n\n<p>Pioglitazone Actavis should be used daily to achieve the desired effect.&nbsp;If you stop taking Pioglitazone Actavis, your blood sugar level may increase.&nbsp;Talk to your doctor before stopping this treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>In particular, patients have experienced the following serious side effects:<\/p>\n\n\n\n<p>Heart failure\u00a0has been common (up to 1 in 10 people) in patients taking pioglitazone in combination with\u00a0insulin.\u00a0The symptoms are abnormal shortness of breath or rapid weight gain or local swelling (\u00a0edema\u00a0).\u00a0Seek medical attention immediately if you experience any of these, especially if you are over 65 years old.<\/p>\n\n\n\n<p>Bladder cancer has been detected in some patients (up to 1 in 100 people) taking pioglitazone.\u00a0Signs and symptoms of this can be blood in the urine, pain when urinating, or urination (sudden need to urinate).\u00a0Contact your doctor as soon as possible if you experience any of these symptoms.<\/p>\n\n\n\n<p>It has also been very common for patients taking pioglitazone in combination with\u00a0insulin\u00a0to experience local swelling (\u00a0edema\u00a0).\u00a0Contact your doctor as soon as possible if you experience this\u00a0side effect.<\/p>\n\n\n\n<p>It has been common (up to 1 in 10 people) for female patients taking pioglitazone to report bone fractures.\u00a0Bone fractures have also been reported in male patients taking pioglitazone (occurring in an unknown number of users).\u00a0Contact your doctor as soon as possible if you experience this\u00a0side effect.<\/p>\n\n\n\n<p>Blurred vision due to swelling (or fluid) in the back of the eye (unknown frequency) has also been reported in patients taking pioglitazone.\u00a0Contact your doctor as soon as possible if you experience this symptom for the first time.\u00a0Also, contact your doctor as soon as possible if you already have blurred vision and the symptom worsens.<\/p>\n\n\n\n<p>Allergic reactions have been reported (no known frequency) in patients taking Pioglitazone Actavis.\u00a0If you get a severe\u00a0allergic reaction\u00a0such as hives or swelling of your face, lips, tongue, or throat, which may cause difficulty breathing or swallowing, stop taking this medicine and contact your doctor immediately.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that have occurred in patients taking pioglitazone are:<\/p>\n\n\n\n<p>common (can affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>respiratory tract infection<\/li><li>visual impairment<\/li><li>weight gain<\/li><li>numbness<\/li><\/ul>\n\n\n\n<p>less common (may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sinusitis<\/li><li>insomnia<\/li><\/ul>\n\n\n\n<p>no known frequency (can not be calculated from the available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>elevated levels of liver enzymes<\/li><li>allergic reactions<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that have occurred in some patients who have used pioglitazone with any other antidiabetic medicine are:<\/p>\n\n\n\n<p>very common (may affect more than 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased blood sugar (hypoglycemia)<\/li><\/ul>\n\n\n\n<p>common (can affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>dizziness<\/li><li>joint pain<\/li><li>impotence<\/li><li>back pain<\/li><li>respiratory distress<\/li><li>a slight decrease in the number of&nbsp;red blood cells<\/li><li>weather voltage<\/li><\/ul>\n\n\n\n<p>less common (may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sugar in the urine, egg whites in the urine<\/li><li>increase&nbsp;in&nbsp;enzymes<\/li><li>dizziness<\/li><li>sweating<\/li><li>fatigue<\/li><li>increased appetite<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pioglitazone Actavis<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after the words \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions are required for this medicine.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is pioglitazone. Each tablet contains 15 mg, 30 mg, or 45 mg of pioglitazone (in the form of hydrochloride). Each tablet contains 15 mg of pioglitazone (in the form of hydrochloride). Each tablet contains 30 mg of pioglitazone (in the form of hydrochloride). Each tablet contains 45 mg of pioglitazone (in the form of hydrochloride).\u00a0<\/li><li>The other ingredients are\u00a0lactose monohydrate, hydroxypropylcellulose, carmellose calcium, and magnesium stearate.<\/li><\/ul>\n\n\n\n<p><strong>What the medicine looks like and the contents of the pack<\/strong><\/p>\n\n\n\n<p>Pioglitazone Actavis 15 mg tablets are white, round, flat, beveled, 5.5 mm in diameter, and engraved with \u201cTZ15\u201d on one side.<\/p>\n\n\n\n<p>Pioglitazone Actavis 30 mg tablets are white, round, flat, beveled, 7 mm in diameter, and engraved with \u201cTZ30\u201d on one side.<\/p>\n\n\n\n<p>Pioglitazone Actavis 45 mg tablets are white, round, flat, beveled, 8 mm in diameter, and engraved with \u201cTZ45\u201d on one side.<\/p>\n\n\n\n<p>The tablets are delivered in blister packs of aluminum with 14, 28, 30, 50, 56, 84, 90, 98, or 100 tablets.<\/p>\n\n\n\n<p>The packs of 14, 28, 56, 84, and 98 tablets contain blisters with abbreviations for the days of the week printed on the blister (Mon, Tue, Wed, Thu, Fri, Sat, Sun).<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Natives approved for sale<\/em>&nbsp;:<\/p>\n\n\n\n<p>Actavis Group PTC EHF.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>220 Hafnarfjordur<\/p>\n\n\n\n<p>Iceland<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Actavis Ltd.<\/p>\n\n\n\n<p>BLB 015-016 Bulebel Industrial Estate<\/p>\n\n\n\n<p>Zejtun ZTN 3000<\/p>\n\n\n\n<p>Malta<\/p>\n\n\n\n<p>Further information on this medicine can be obtained from the representative of the marketing authorization holder:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Actavis Group PTC ehf.Iceland \/ Iceland \/ IcelandTel: +354 5503300<\/td><td><strong>Lithuania<\/strong>UAB Teva BalticsTel: +370 52660203<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Teva TV LADTel: +359 24899585<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Teva Pharmaceuticals CR, sroTel: +420 251 007 111<\/td><td><strong>Hungary<\/strong>Teva Gy\u00f3gyszergy\u00e1r Zrt.Tel: +36 12886400<\/td><\/tr><tr><td><strong>Denmark<\/strong>Teva Denmark A \/ STel: +45 44 98 55 11<\/td><td><strong>Malta<\/strong>Teva Pharmaceuticals IrelandL-IrelandTel: +44 2075407117<\/td><\/tr><tr><td><strong>Germany<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><td><strong>The Netherlands<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><\/tr><tr><td><strong>Eesti<\/strong>UAB Teva Baltics Eesti subsidiaryTel: +372 6610801<\/td><td><strong>Norway<\/strong>Teva Norway ASTel: +47 66775590<\/td><\/tr><tr><td><strong>Greece<\/strong>Specify ABEE:\u0397\u03bb: +30 2118805000<\/td><td><strong>Austria<\/strong>ratiopharm Arzneimittel Vertriebs-GmbHTel: +43 1970070<\/td><\/tr><tr><td><strong>Spain<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><td><strong>Poland<\/strong>Teva Pharmaceuticals Polska Sp.&nbsp;z ooTel: +48 223459300<\/td><\/tr><tr><td><strong>France<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><td><strong>Portugal<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pliva Hrvatska dooTel: +385 13720000<\/td><td><strong>Romania<\/strong>Teva Pharmaceuticals SRLTel: +40 212306524<\/td><\/tr><tr><td><strong>Ireland<\/strong>Teva Pharmaceuticals IrelandTel: +44 2075407117<\/td><td><strong>Slovenia<\/strong>Pliva Ljubljana dooTel: +386 15890390<\/td><\/tr><tr><td><strong>Iceland<\/strong>Actavis Group PTC ehf.Phone: +354 5503300<\/td><td><strong>Slovak Republic<\/strong>TEVA Pharmaceuticals Slovakia sroTel: +421 257267911<\/td><\/tr><tr><td><strong>Italy<\/strong>Actavis Group PTC ehf.IcelandTel: +354 5503300<\/td><td><strong>Finland \/ Finland<\/strong>Teva Finland OyPuh \/ Tel: +358 201805900<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>Specify ABEEGreece:\u0397\u03bb: +30 2118805000<\/td><td><strong>Sweden<\/strong>Teva Sweden ABTel: +46 42121100<\/td><\/tr><tr><td><strong>Latvia<\/strong>UAB Teva Baltics subsidiary Latvij\u0101Tel: +371 67323666<\/td><td><strong>United Kingdom<\/strong>Teva Pharmaceuticals IrelandIrelandTel: +44 2075407117<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Pioglitazone Actavis contains pioglitazone. It is an antidiabetic medicine used to treat type 2 diabetes mellitus , when metformin is not suitable or has sufficient effect. This type of diabetes is also called &#8220;non-insulin dependent&#8221; and usually occurs in adulthood.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[11721,21394,6691,21390,21393,21395,6693,6694,6692,21391,21392,12895],"class_list":["post-20878","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pioglitazone","tag-benefits-of-pioglitazone-actavis","tag-pioglitazone","tag-pioglitazone-actavis","tag-pioglitazone-actavis-side-effects","tag-pioglitazone-actavis-tablet","tag-pioglitazone-side-effects","tag-pioglitazone-tablet","tag-what-is-pioglitazone","tag-what-is-pioglitazone-actavis","tag-what-pioglitazone-actavis-is-used-for","tag-what-pioglitazone-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20878"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20878\/revisions"}],"predecessor-version":[{"id":20928,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20878\/revisions\/20928"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20878"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20878"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}