{"id":20864,"date":"2022-04-15T15:31:39","date_gmt":"2022-04-15T15:31:39","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20864"},"modified":"2022-04-18T17:08:04","modified_gmt":"2022-04-18T17:08:04","slug":"pilexam","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pilexam\/","title":{"rendered":"Pilexam &#8211; Tranexamic acid uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg \/ ml&nbsp;solution&nbsp;for injection<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tranexamic-acid-accord\/\">tranexamic acid<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pilexam is and what it is used for<\/h2>\n\n\n\n<p>Pilexam contains\u00a0tranexamic acid, which belongs to a group of medicines called hemostatics;<br>fibrinolysis inhibitors,\u00a0amino acids.<br>Pilexam is used in adults and children over 1 year of age to prevent and treat bleeding due to\u00a0fibrinolysis, which means that the blood has difficulty coagulating.<\/p>\n\n\n\n<p>Specific uses include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heavy menstruation in women<\/li><li>Bleeding in the stomach\/intestine<\/li><li>Urinary tract bleeding after prostate surgery or surgery that affects the urinary tract<\/li><li>Ear, nose, or throat surgery<\/li><li>Cardiovascular surgery, abdominal surgery, or gynecological surgery<\/li><li>Bleeding after you have been treated with another anticoagulant.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Pilexam<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pilexam<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;tranexamic acid&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have a disease that causes you to get blood clots<\/li><li>if you have a disease called &#8220;consumption coagulopathy&#8221;, in which the blood throughout the body begins to form blood clots<\/li><li>if you have kidney problems<\/li><li>if you have had seizures in the past.<\/li><\/ul>\n\n\n\n<p>Due to the risk of brain&nbsp;edema&nbsp;and seizures, use in the brain (&nbsp;intrathecal&nbsp;and&nbsp;intraventricular&nbsp;injection&nbsp;or intracerebral application) is not recommended.<\/p>\n\n\n\n<p>If you think any of the above applies to you, or if you have any further questions, ask your doctor or doctor before taking Pilexam.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before using Pilexam.<br>Tell your doctor if any of the following apply to you to help him or she decides if Pilexam is right for you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have had blood in your urine: Pilexam may obstruct the urethra.<\/li><li>If you have an increased risk of getting blood clots.<\/li><li>If you have severe coagulation or bleeding throughout the body (disseminated intravascular\u00a0coagulation\u00a0), Pilexam may not be suitable for you, unless you have\u00a0acute\u00a0severe bleeding and blood tests have shown that the process inhibits the blood&#8217;s ability to coagulate (\u00a0fibrinolysis\u00a0) has been activated.<\/li><li>If you have had seizures before, you should not be treated with Pilexam.\u00a0Your doctor should use the lowest possible\u00a0dose\u00a0to avoid seizures during treatment with Pilexam.<\/li><li>If you are on long-term treatment with Pilexam, any changes in color vision should be monitored, and if necessary, treatment should be stopped.\u00a0If you continue to use Pilexam for long-term use, you should have regular eye examinations (check for\u00a0visual acuity, color vision, fundus,\u00a0visual field, etc.).\u00a0In case of eye changes, especially diseases of the retina, the doctor should, after consultation with a specialist, decide whether long-term treatment with Pilexam is necessary in your case.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pilexam<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br>In particular, tell your doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other drugs to make the blood coagulate, so-called antifibrinolytic agents<\/li><li>drugs that prevent blood clots, so-called thrombolytic drugs<\/li><li>birth control pills.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br>Tranexamic acid\u00a0is excreted in breast milk.\u00a0The use of Pilexam during breastfeeding is therefore not recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No studies have been performed on the ability to drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pilexam<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Use in adults<\/strong><br>Pilexam will be given to you by a slow&nbsp;injection&nbsp;into a blood vessel.&nbsp;Your doctor will decide which&nbsp;dose&nbsp;is right for you and for how long you should be treated.<\/p>\n\n\n\n<p><strong>Use in children<\/strong><br>If Pilexam&nbsp;solution for injection&nbsp;is given to children from 1 year of age,&nbsp;dose&nbsp;one is based on the weight of the child.&nbsp;The doctor decides which&nbsp;dose&nbsp;is appropriate and how long the child should be treated.<\/p>\n\n\n\n<p><strong>Use in the elderly<\/strong><br>No dose reduction is required unless there is evidence of\u00a0renal failure.<\/p>\n\n\n\n<p><strong>Use in patients with renal impairment<\/strong><br>In renal impairment, the&nbsp;dose&nbsp;of&nbsp;tranexamic acid will&nbsp;be reduced by taking a blood test (serum creatinine value).<\/p>\n\n\n\n<p><strong>Use in patients with hepatic impairment<\/strong><br>No dose reduction is required.<\/p>\n\n\n\n<p><strong>Method of administration<\/strong><br>Pilexam should only be administered slowly in a blood vessel.<br>Pilexam must not be injected into a muscle.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Pilexam than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>If you receive more Pilexam than the recommended\u00a0dose, you may experience a transient drop in blood pressure.\u00a0Talk to a doctor or pharmacist immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Side effects&nbsp;reported for tranexamic acid:<\/strong><br>The following&nbsp;side effects&nbsp;have been observed for tranexamic acid:<br>Common (may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>gastrointestinal disorders: nausea, vomiting, diarrhea<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin effect: rash<\/li><\/ul>\n\n\n\n<p>No known frequency (frequency can not be calculated from available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feeling sick with low\u00a0blood pressure, especially if the\u00a0injection\u00a0has been given too quickly<\/li><li>blood clots<\/li><li>effects on the nervous system: seizures<\/li><li>effects on the eyes: changes in vision including impaired color vision<\/li><li>effects on the immune system: allergic reactions<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pilexam<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>No special storage instructions.<br>Do not use this medicine after the expiry date which is stated on the label after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is\u00a0tranexamic acid.\u00a0Each 1 ml solution contains 100 mg\u00a0tranexamic acid.<\/li><li>The other ingredients are water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Clear&nbsp;ampoule&nbsp;in type I glass containing 5 ml.&nbsp;Carton of 10 ampoules x 5 ml.<br>Clear&nbsp;ampoule&nbsp;in type I glass containing 10 ml.&nbsp;Carton of 10 ampoules x 10 ml.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Pilum Pharma A \/ S, Energivej 15, 5260 Odense S, Denmark<\/p>\n\n\n\n<p><em>Local representative<\/em><\/p>\n\n\n\n<p>Orifarm Generics AB, Box 56048, 102 17 Stockholm, info@orifarm.com<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><br>Medochemie Ltd.<br>Ampoule Injectable Facility: 48 Iapetou Street, Agios Athanassios Industrial Area, 4101 Agios<br>Athanassios, Limassol<br>Cyprus<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pilexam contains tranexamic acid , which belongs to a group of medicines called hemostatics;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21428,21423,21424,21427,6309,6313,21425,6310,21426,21422],"class_list":["post-20864","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pilexam","tag-benefits-of-tranexamic-acid","tag-pilexam","tag-pilexam-side-effects","tag-tranexamic-acid","tag-tranexamic-acid-side-effects","tag-what-is-pilexam","tag-what-is-tranexamic-acid","tag-what-pilexam-is-used-for","tag-what-tranexamic-acid-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20864","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20864"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20864\/revisions"}],"predecessor-version":[{"id":20932,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20864\/revisions\/20932"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20864"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20864"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20864"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}