13.6 mg \/ ml (1.36% w \/ v), 22.7 mg \/ ml (2.27% w \/ v), 38.6 mg \/ ml (3.86% w \/ v) peritoneal dialysis fluid<\/p>\n\n\n\n
Physioneal 40\u00a0Glucose\u00a0is a\u00a0peritoneal dialysis fluid.\u00a0It removes water and waste products from the blood.\u00a0It also corrects abnormal levels of various components in the blood.\u00a0Physioneal 40\u00a0Glucose\u00a0is available with different glucose contents (1.36%, 2.27%, and 3.86%).\u00a0The higher the glucose content of the solution, the more water it will remove from the blood.<\/p>\n\n\n\n
Physioneal 40 Glucose can be prescribed to you if you suffer from:<\/p>\n\n\n\n
\u2022 either temporary or permanent renal failure<\/p>\n\n\n\n
\u2022 heavy accumulation of water in the body,<\/p>\n\n\n\n
\u2022 severe disturbances in acidity or alkalinity ( pH ) and salt levels in the blood<\/p>\n\n\n\n
\u2022 certain types of drug poisoning where no other treatment is available<\/p>\n\n\n\n
Physioneal 40 Glucose has an acidity ( pH ) that is close to the blood. Therefore, it can be especially useful if you experience pain or discomfort when ingesting other peritoneal dialysis fluids that are more acidic (have a lower pH ).<\/p>\n\n\n\n
The first time you use the product, a doctor should monitor the procedure.<\/p>\n\n\n\n
-if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n
– if you have problems that affect the abdominal wall or abdominal cavity and that can not be operated on or if you have non-correctable problems that lead to an increased risk of abdominal infections<\/p>\n\n\n\n
– if you have documented impaired peritoneal function due to severe scarring of the peritoneum.<\/p>\n\n\n\n
Talk to your doctor before using Physioneal 40\u00a0Glucose.<\/p>\n\n\n\n
Be especially careful:<\/p>\n\n\n\n
– If you have problems affecting the abdominal wall or abdominal cavity. For example, if you have a hernia or a chronic infectious or chronic inflammatory condition that affects your intestines.<\/p>\n\n\n\n
– If you have a (graft) prosthesis in the large carotid artery.<\/p>\n\n\n\n
– If you have severe breathing problems.<\/p>\n\n\n\n
– If you experience stomach pain, fever, or notice that the dialysate is cloudy, cloudy, or contains particles.\u00a0It may be a sign of\u00a0peritonitis\u00a0(inflamed peritoneum) or\u00a0infection.\u00a0Contact your medical care team immediately.\u00a0Make a note of the batch number and take it with you to the dialysate bag for your healthcare team.\u00a0They will decide if the treatment should be stopped or if any other treatment needs to be started.\u00a0For example, if you have an\u00a0infection, your doctor may take certain samples to find out which\u00a0antibiotic\u00a0is best for you.\u00a0Until the doctor knows what kind of\u00a0infection\u00a0you have, you can get an\u00a0antibiotic that is effective against a large number of different bacteria.\u00a0This is called a broad-spectrum antibiotic.<\/p>\n\n\n\n
– If you have a high level of lactic acid in your blood. You have a greater risk of lactic acidosis if:<\/p>\n\n\n\n
\u2022 you have very low blood pressure<\/p>\n\n\n\n
\u2022 you have an infection in the blood<\/p>\n\n\n\n
\u2022 you have acute kidney failure<\/p>\n\n\n\n
\u2022 you have a congenital metabolic disorder<\/p>\n\n\n\n
\u2022 you are taking metformin (a medicine used to treat diabetes )<\/p>\n\n\n\n
\u2022 you are taking medicines for\u00a0HIV, especially medicines called NRTIs.<\/p>\n\n\n\n
– If you have diabetes and use this fluid, the dose of one of the medicines used to adjust your blood sugar level (eg insulin ) should be evaluated regularly. Especially when peritoneal dialysis treatment is started or changed, the dose of one of your diabetes medicines may need to be adjusted.<\/p>\n\n\n\n
-If you are allergic to corn which can cause\u00a0hypersensitivity reaction, including a severe\u00a0allergic reaction, so-called\u00a0anaphylaxis.\u00a0Discontinue the\u00a0infusion\u00a0immediately and remove the solution from the abdominal cavity.<\/p>\n\n\n\n
– If you have a high level of parathyroid hormone in your blood due to your kidney disease. The low level of calcium in Physioneal 40 Glucose may aggravate hyperparathyroidism. Your doctor will monitor the level of parathyroid hormone in your blood.<\/p>\n\n\n\n
– You should, possibly in consultation with your doctor, keep a record of fluid balance and body weight.\u00a0Your doctor will monitor your blood levels at regular intervals.\u00a0Especially for salts (eg\u00a0bicarbonate,\u00a0potassium,\u00a0magnesium,\u00a0calcium,\u00a0and\u00a0phosphate\u00a0), parathyroid hormone, and fats.<\/p>\n\n\n\n
– If you have high levels of bicarbonate in your blood.<\/p>\n\n\n\n
– Do not use more solutions than your doctor prescribed.\u00a0Symptoms of over-infusion are a feeling of tension in the abdomen, a feeling of satiety, and shortness of breath.<\/p>\n\n\n\n
– Your doctor will measure your potassium levels regularly. If they get too low, you can get potassium chloride to compensate.<\/p>\n\n\n\n
– If\u00a0flushing\u00a0or opening and closing of clamps is done in the wrong order, it can result in air entering the abdominal cavity, which can cause abdominal pain and\/or\u00a0peritonitis<\/p>\n\n\n\n
– If you infuse an unmixed bag, empty the solution immediately and use a freshly mixed bag.<\/p>\n\n\n\n
A condition called encapsulating peritoneal sclerosis (EPS) is a known, rare complication of peritoneal dialysis treatment. You should, possibly in consultation with your doctor, be aware of this possible complication. Encapsulating peritoneal sclerosis causes:<\/p>\n\n\n\n
\u2022 inflammation of the abdomen (stomach)<\/p>\n\n\n\n
\u2022 thickening of the intestines that can lead to abdominal pain, distended abdomen, or vomiting.\u00a0EPS can be fatal.<\/p>\n\n\n\n
Your doctor will weigh the risk against the benefits of this medicine if you are younger than 18 years old.<\/p>\n\n\n\n
Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.<\/p>\n\n\n\n
If you are taking other medicines, your doctor may need to increase the dose of one of these. This is because treatment with peritoneal dialysis increases the secretion of certain drugs.<\/p>\n\n\n\n
\u2022 If you are taking heart medicines called cardiac glycosides (eg digoxin ) you can:<\/p>\n\n\n\n
\u2022 Need potassium and calcium supplements.<\/p>\n\n\n\n
\u2022 Develop an irregular heartbeat ( arrhythmia )<\/p>\n\n\n\n
\u2022 Your doctor will monitor your treatment closely, especially your potassium levels.<\/p>\n\n\n\n
If you are pregnant, breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0The doctor decides whether the treatment is appropriate or not.<\/p>\n\n\n\n
This treatment can cause fatigue, weakness, blurred vision, and dizziness.\u00a0Do not drive or use any tools or machines if you are affected.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Physioneal 40 Glucose should be inserted into the abdominal cavity. It is the space in the abdomen (stomach) between the skin and the peritoneum. The peritoneum is the membrane that surrounds the internal organs such as the intestines and liver.<\/p>\n\n\n\n
It is not for intravenous use.<\/p>\n\n\n\n
Always use this medicine exactly according to the instructions of the care team that specializes in\u00a0peritoneal dialysis.\u00a0Consult a doctor if you are unsure.<\/p>\n\n\n\n
If the bag is damaged, it must be discarded.<\/p>\n\n\n\n
How much and how often<\/strong><\/p>\n\n\n\n Your doctor will prescribe the appropriate glucose strength and the appropriate number of bags for you to use each day.<\/p>\n\n\n\n Use for children and adolescents<\/strong><\/p>\n\n\n\n If you are under 18 years of age, your doctor will carefully assess the prescription of this medicine.<\/p>\n\n\n\n If you stop using Physioneal 40 Glucose<\/strong><\/p>\n\n\n\n Do not stop treatment with peritoneal dialysis without your doctor’s consent. Discontinuation of treatment may have life-threatening consequences.<\/p>\n\n\n\n Method of use<\/strong><\/p>\n\n\n\n Before use:<\/p>\n\n\n\n \u2022 Heat the bag to 37 \u00b0 C. Use a hot plate designed for this purpose. Never immerse in water. The bag must not be heated in the microwave.<\/p>\n\n\n\n Use the aseptic technique throughout the\u00a0administration\u00a0of one of the solutions, as you have learned.<\/p>\n\n\n\n \u2022 Before starting a solution change, wash your hands and the surface where the change is to be made.<\/p>\n\n\n\n \u2022 Before opening the outer bag, check that it is the correct solution, expiry date, and quantity (volume).\u00a0Lift the dialysis bag to check for leaks (excess fluid in the outer bag).\u00a0Do not use the bag if leakage is detected.<\/p>\n\n\n\n \u2022 After the outer bag has been removed, check the container for signs of leakage by pressing the bag firmly. Check that the breaker pin between the chambers is not interrupted. Discard the bag if the breaker pin is already broken. Do not use the bag if leakage is detected.<\/p>\n\n\n\n \u2022 Check that the solution is ready. Do not use the bag if the solution is cloudy or contains particles.<\/p>\n\n\n\n \u2022 Make sure that all connections are secure before starting the change.<\/p>\n\n\n\n \u2022 Mix the contents of the two chambers thoroughly by breaking the brake pin.\u00a0Wait until the small chamber is completely emptied into the large chamber.\u00a0Mix gently by pressing with both hands on the walls of the large chamber.<\/p>\n\n\n\n Ask your doctor if you have any questions or concerns about this product or its use.<\/p>\n\n\n\n \u2022 Each bag may only be used once. Discard any remaining solution.<\/p>\n\n\n\n \u2022 The solution must be used within 24 hours after\u00a0mixing.<\/p>\n\n\n\n After use, check that the drained liquid is not cloudy.<\/p>\n\n\n\n Compatibility with other drugs<\/strong><\/p>\n\n\n\n Your doctor may\u00a0prescribe\u00a0other injectable medicines to be added directly to the Physioneal 40\u00a0Glucose bag.\u00a0In this case, the drug should be added through the injection port in the small chamber before breaking the broken pin between the two chambers.\u00a0Use the product immediately after the drug has been added.\u00a0Ask your doctor if you are unsure.<\/p>\n\n\n\n If you use more Physioneal 40 Glucose bags than you should for 24 hours<\/strong><\/p>\n\n\n\n If you infuse too much Physioneal 40\u00a0Glucose, you may get:<\/p>\n\n\n\n – stretched abdomen<\/p>\n\n\n\n feeling full and\/or<\/p>\n\n\n\n – shortness of breath.<\/p>\n\n\n\n Contact your doctor immediately.\u00a0He\/she decides on any action.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Tell your doctor or dialysis clinic immediately if you experience any of the following:<\/p>\n\n\n\n \u2022 Hypertension ( blood pressure is higher than usual)<\/p>\n\n\n\n \u2022 Swollen ankles and legs, swelling around the eyes, shortness of breath, or chest pain (increased blood volume).<\/p>\n\n\n\n \u2022 Abdominal pain.<\/p>\n\n\n\n Chills (chills \/ flu-like symptoms)<\/p>\n\n\n\n Inflamed\u00a0peritonitis.<\/p>\n\n\n\n These are serious\u00a0side effects.\u00a0You need to get medical attention quickly.<\/p>\n\n\n\n If you get any\u00a0side effects, talk to your doctor or doctor.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.<\/p>\n\n\n\n Common side effects (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n \u2022 Changing your blood tests:<\/p>\n\n\n\n – increase in calcium ( hypercalcemia )<\/p>\n\n\n\n – decrease in\u00a0potassium\u00a0(\u00a0hypokalaemia\u00a0), which can cause muscle weakness, twitching, and abnormal heart rhythm.<\/p>\n\n\n\n – increase in bicarbonate ( alkalosis )<\/p>\n\n\n\n Weakness, fatigue<\/p>\n\n\n\n \u2022 Fluid retention ( edema )<\/p>\n\n\n\n \u2022 Weight gain<\/p>\n\n\n\n Uncommon side effects (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n – Reduced fluid secretion during\u00a0dialysis.<\/p>\n\n\n\n Fainting, tiredness, or headache.<\/p>\n\n\n\n – Turbid dialysate from the abdominal cavity, abdominal pain.<\/p>\n\n\n\n – Bleeding in the abdominal cavity, scarring, swelling,\u00a0or\u00a0pain at the starting point of the catheter, stop in the catheter.<\/p>\n\n\n\n – Nausea, decreased appetite, indigestion, flatulence (thirst), thirst, dry mouth<\/p>\n\n\n\n – Stretched abdomen or inflammation in the abdomen, pain in the shoulders, hernia in the abdominal cavity (bulging in the groin).<\/p>\n\n\n\n – Changing your blood tests:<\/p>\n\n\n\n – lactic acidosis<\/p>\n\n\n\n increased carbon dioxide content<\/p>\n\n\n\n – increased sugar content (hyperglycemia)<\/p>\n\n\n\n – increased white blood cell count ( eosinophilia )<\/p>\n\n\n\n – Difficulty sleeping<\/p>\n\n\n\n – Low blood pressure ( hypotension )<\/p>\n\n\n\n – Hosta<\/p>\n\n\n\n – Pain in muscles or legs<\/p>\n\n\n\n – Swelling of the face or neck<\/p>\n\n\n\n Rash<\/p>\n\n\n\n Other side effects associated with peritoneal dialysis treatment:<\/em><\/p>\n\n\n\n – infection at the catheter starting point, stop in the catheter.<\/p>\n\n\n\n \u2022 Keep this medicine out of the reach and sight of children<\/p>\n\n\n\n \u2022 Store in the original packaging<\/p>\n\n\n\n \u2022 Do not store below 4 \u00b0 C<\/p>\n\n\n\n \u2022 Use before the expiry date which is stated on the carton and the bag after the abbreviation\u00a0EXP\u00a0.\u00a0or\u00a0EXP\u00a0and the symbol.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n Dispose of Physioneal 40 Glucose according to the instructions given to you.<\/p>\n\n\n\n This leaflet does not contain all the information about the medicine. Ask your doctor if you have any questions or are unsure.<\/p>\n\n\n\n The active substances in the\u00a0mixed<\/strong>\u00a0peritoneal dialysis fluid are:<\/p>\n\n\n\n The other ingredients are water for injections and\u00a0carbon dioxide.<\/p>\n\n\n\n Composition in mmol \/ l in the\u00a0mixed<\/strong>\u00a0solution is:<\/p>\n\n\n\n What the medicine looks like and the contents of the pack<\/strong><\/p>\n\n\n\n \u2022 Physioneal 40\u00a0Glucose\u00a0is a clear, colorless,\u00a0sterile\u00a0solution for\u00a0peritoneal dialysis.<\/p>\n\n\n\n \u2022 Physioneal 40 Glucose is packaged in PVC bags with two chambers. The two chambers are separated by a permanent closure. Physioneal 40 Glucose must not be given until the solutions in the two chambers have been mixed properly.<\/p>\n\n\n\n \u2022 Each bag is packed in an outer bag and the bags are delivered in a carton.<\/p>\n\n\n\n The line coupling contains iodine.<\/p>\n\n\n\n Not all pack sizes may be marketed.<\/p>\n\n\n\n Further information on this medicine can be obtained from the representative of the marketing authorization holder:<\/p>\n\n\n\n Manufacturer: <\/strong><\/p>\n\n\n\n Baxter and Physioneal are trademarks of Baxter International Inc.<\/p>\n","protected":false},"excerpt":{"rendered":" Physioneal 40 Glucose is a peritoneal dialysis fluid . It removes water and waste products from the blood. It also corrects abnormal levels of various components in the blood. Physioneal 40 Glucose is available with different glucose contents (1.36%, 2.27% and 3.86%). The higher the glucose content of the solution, the more water it will remove from the blood.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[19402,21271,3276,3279,21267,21270,8834,21268,8835,21269],"class_list":["post-20817","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-peritoneal-dialysis-fluid","tag-benefits-of-physioneal-40-glucose","tag-peritoneal-dialysis-fluid","tag-peritoneal-dialysis-fluid-side-effects","tag-physioneal-40-glucose","tag-physioneal-40-glucose-side-effects","tag-what-is-peritoneal-dialysis-fluid","tag-what-is-physioneal-40-glucose","tag-what-peritoneal-dialysis-fluid-is-used-for","tag-what-physioneal-40-glucose-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20817"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20817\/revisions"}],"predecessor-version":[{"id":20857,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20817\/revisions\/20857"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Possible side effects<\/h2>\n\n\n\n
How to store Physioneal 40 Glucose<\/h2>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
<\/td> 13.6 mg \/ ml<\/strong><\/td> 22.7 mg \/ ml<\/strong><\/td> 38.6 mg \/ ml<\/strong><\/td><\/tr> Glucose monohydrate (g \/ l)<\/td> 15.0<\/td> 25.0<\/td> 42.5<\/td><\/tr> corresponds to anhydrous glucose (g \/ l)<\/td> 13.6<\/td> 22.7<\/td> 38.6<\/td><\/tr> Sodium chloride (g \/ l)<\/td> 5.38<\/td> 5.38<\/td> 5.38<\/td><\/tr> Calcium chloride dihydrate (g \/ l)<\/td> 0.184<\/td> 0.184<\/td> 0.184<\/td><\/tr> Magnesium chloride hexahydrate (g \/ l)<\/td> 0.051<\/td> 0.051<\/td> 0.051<\/td><\/tr> Sodium bicarbonate (g \/ l)<\/td> 2.10<\/td> 2.10<\/td> 2.10<\/td><\/tr> Sodium (S) -lactate solution (g \/ l)<\/td> 1.68<\/td> 1.68<\/td> 1.68<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n <\/td> 13.6 mg \/ ml<\/strong><\/td> 22.7 mg \/ ml<\/strong><\/td> 38.6 mg \/ ml<\/strong><\/td><\/tr><\/thead> Anhydrous glucose (mmol \/ l)<\/td> 75.5<\/td> 126<\/td> 214<\/td><\/tr> Sodium (mmol \/ l)<\/td> <\/td> 132<\/td> <\/td><\/tr> Calcium (mmol \/ l)<\/td> <\/td> 1.25<\/td> <\/td><\/tr> Magnesium (mmol \/ l)<\/td> <\/td> 0.25<\/td> <\/td><\/tr> Chlorides (mmol \/ l)<\/td> <\/td> 95<\/td> <\/td><\/tr> Bicarbonate (mmol \/ l)<\/td> <\/td> 25<\/td> <\/td><\/tr> Lactate (mmol \/ l)<\/td> <\/td> 15<\/td> <\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n Volume<\/td> Number in each box<\/td> Pack size<\/td> Type of coupling<\/td><\/tr> 1.5 l<\/td> 5\/6<\/td> Single bag (APD)<\/td> Screw \/ Tip<\/td><\/tr> 1.5 l<\/td> 5\/6<\/td> DUO bag ( CAPD )<\/td> Screw \/ Tip \/ Lineo<\/td><\/tr> 2.0 l<\/td> 4\/5<\/td> Single bag (APD)<\/td> Screw \/ Tip<\/td><\/tr> 2.0 l<\/td> 4\/5<\/td> DUO bag ( CAPD )<\/td> Screw \/ Tip \/ Lineo<\/td><\/tr> 2.5 l<\/td> 4\/5<\/td> Single bag (APD)<\/td> Screw \/ Tip<\/td><\/tr> 2.5 l<\/td> 4\/5<\/td> DUO bag ( CAPD )<\/td> Screw \/ Tip \/ Lineo<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Sweden:<\/strong>
Baxter Medical AB
Box 63
164 94 KistaTel: 08 – 632 64 00<\/td>Finland:<\/strong>
Baxter Oy
Box 119
FI-00181 Helsinki tel.\u00a009 – 862 1111<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\nBaxter Healthcare SA
Moneen Road
CastlebarCounty Mayo- Ireland<\/td><\/tr>
Bieffe Medital SpAVia Nuova Provinciale23034 Grosotto, Italy<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n