1.2 mmol \/ l phosphate hemodialysis fluid \/ haemofiltration fluid
calcium chloride dihydrate, magnesium chloride hexahydrate, sodium chloride, sodium bicarbonate, potassium chloride, disodium phosphate dihydrate<\/p>\n\n\n\n
Phoxilium belongs to the group of haemofiltration fluids and contains calcium chloride dihydrate, magnesium chloride hexahydrate, sodium chloride, sodium bicarbonate, potassium chloride and disodium phosphate dihydrate.<\/p>\n\n\n\n
Phoxilium is used in hospitals in intensive care to correct chemical imbalances in the blood caused by kidney damage.<\/p>\n\n\n\n
Continuous kidney replacement therapy<\/strong> is used to remove waste products from the blood that have accumulated when the kidneys are not functioning.<\/p>\n\n\n\n Phoxilium solution<\/strong> is mainly used to treat critically ill patients with acute kidney injury and:<\/p>\n\n\n\n This drug can also be used for drug poisoning or intoxication of dialyzable or filterable substances.<\/p>\n\n\n\n Do not use hemodialysis or haemofiltration in any of the following three cases:<\/strong><\/p>\n\n\n\n Talk to your doctor, pharmacist or nurse before using Phoxilium.<\/p>\n\n\n\n Before and during treatment, your blood condition will be checked and, for example, the acid \/ base balance and salt concentration in the blood ( electrolytes ) will be<\/em> monitored, including all fluid supply ( intravenous infusion ) and all fluid withdrawals (urine production), even those not directly related to the treatment. .<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is important because the concentration of other medicines may affect the treatment with Phoxilium. Your doctor will decide if the dosage of any of the medicines you are taking may need to be adjusted. Pregnancy and breast-feeding:<\/p>\n\n\n\n There are no documented clinical data on the use of this medicine during pregnancy or lactation. This medicine should only be given to pregnant or lactating women if there is a clear need.<\/p>\n\n\n\n Fertility:<\/p>\n\n\n\n No effects on fertility are expected as calcium , sodium , potassium , magnesium , chloride, hydrogen phosphate and bicarbonate are normal constituents of the body.<\/p>\n\n\n\n Phoxilium does not affect the ability to drive or use machines.<\/p>\n\n\n\n Phoxilium should be used in hospitals and only administered by healthcare professionals. The volume of Phoxilium, and thus the dose used, will depend on your condition. Dosage one will be determined by the doctor responsible for your treatment. Always use this medicine exactly as your doctor, pharmacist or nurse has told you.\u00a0If you are not sure, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n Phoxilium should be used in a hospital and only administered by healthcare professionals, and your fluid balance and blood status will be closely monitored.<\/p>\n\n\n\n It can lead to serious consequences, such as heart failure or blood disorder.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them. Some side effects can be\u00a0caused by\u00a0dialysis treatments, such as:<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the label and the carton.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n Store between + 4 \u00b0 C and + 30 \u00b0 C. Store in a cold place. Do not freeze.<\/p>\n\n\n\n For the reconstituted solution, chemical and physical in-use stability have been demonstrated for up to 24 hours at 22 \u00b0 C.\u00a0If not used immediately, in-use storage times and conditions before\u00a0administration\u00a0are the responsibility of the user and should not exceed 24 hours, including treatment time.<\/p>\n\n\n\n Do not use this medicine if the solution is cloudy or if the cover is damaged. All seals must be unbroken.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substances before and after reconstitution ( mixture ) are shown below.<\/p>\n\n\n\n Active substances before reconstitution:<\/strong> 1,000 ml solution from\u00a0the large chamber (B)<\/strong>\u00a0contains:<\/p>\n\n\n\n Active substances after reconstitution:<\/strong> Theoretical osmolarity: 293 mOsm \/ l<\/p>\n\n\n\n Other ingredients are:<\/strong><\/p>\n\n\n\n Phoxilium is a solution for\u00a0hemodialysis\u00a0and\u00a0hemofiltration\u00a0and is packaged in a two-chamber bag.\u00a0The ready-mixed solution is obtained by breaking the seal and mixing the two solutions.\u00a0The reconstituted solution is clear and colorless.\u00a0Each bag (A + B) contains 5,000 ml of solution for\u00a0hemodialysis\u00a0and\u00a0haemofiltration.\u00a0The bag is covered with a transparent film. Baxter Holding BV<\/p>\n\n\n\n Kobaltweg 49<\/p>\n\n\n\n 3542CE Utrecht<\/p>\n\n\n\n Netherlands<\/p>\n\n\n\n Manufacturer:<\/strong><\/p>\n\n\n\n Bieffe Medital SpA, Via Stelvio 94, 23035 Sondalo (SO), ITALY<\/p>\n\n\n\n Local representative<\/strong><\/p>\n\n\n\n Baxter Medical AB<\/p>\n\n\n\n Box 63<\/p>\n\n\n\n 164 94 Kista<\/p>\n","protected":false},"excerpt":{"rendered":" Phoxilium belongs to the group of haemofiltration fluids and contains calcium chloride dihydrate, magnesium chloride hexahydrate, sodium chloride, sodium bicarbonate, potassium chloride and disodium phosphate dihydrate.uuu<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21283,8764,21278,21277,14284,21279,21282,4230,14699,11616,21280,21281],"class_list":["post-20811","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-phoxilium","tag-disodium-phosphate-dihydrate","tag-haemofiltration-fluid-calcium-chloride-dihydrate","tag-l-phosphate-hemodialysis-fluid","tag-magnesium-chloride-hexahydrate","tag-phoxilium","tag-phoxilium-side-effects","tag-potassium-chloride","tag-sodium-bicarbonate","tag-sodium-chloride","tag-what-is-phoxilium","tag-what-phoxilium-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20811","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20811"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20811\/revisions"}],"predecessor-version":[{"id":20862,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20811\/revisions\/20862"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20811"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20811"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before using Phoxilium<\/h2>\n\n\n\n
Do not use Phoxilium in the following three cases:<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Other drugs and Phoxilium<\/h2>\n\n\n\n
It is especially important that you tell your doctor if you are taking any of the following:<\/p>\n\n\n\nPregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
How to use Phoxilium<\/h2>\n\n\n\n
Phoxilium can be administered directly into the bloodstream ( intravenously<\/em> ) through a CRRT machine or via hemodialysis where the solution flows on one side of a dialysis membrane while the blood flows on the other side.<\/p>\n\n\n\n
Instructions for use can be found in the section “The following information is only intended for healthcare professionals”.<\/p>\n\n\n\nIf you use more Phoxilium than you should <\/h2>\n\n\n\n
Therefore, it is unlikely that you will use too much Phoxilium.<\/strong>
If this is unlikely to happen and you get an overdose, your doctor will take the necessary steps and adjust your\u00a0dose.
Overdose may result in dehydration,\u00a0reduction\u00a0of blood bicarbonate concentration (metabolic\u00a0acidosis\u00a0), and\/or high phosphate levels (\u00a0hyperphosphatemia\u00a0) if you have kidney damage.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
The following three\u00a0side effects may be\u00a0associated with the use of<\/strong>\u00a0Phoxilium\u00a0:<\/p>\n\n\n\nHow to store Phoxilium<\/h2>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
1,000 ml solution from\u00a0the small chamber (A)<\/strong>\u00a0contains:<\/p>\n\n\n\nCalcium chloride, 2 H 2<\/sub> O<\/td> 3.68 g<\/td><\/tr> Magnesium chloride, 6 H 2<\/sub> O<\/td> 2.44 g<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n Sodium chloride<\/td> 6.44 g<\/td><\/tr> Sodium bicarbonate<\/td> 2.92 g<\/td><\/tr> Potassium chloride<\/td> 0.314 g<\/td><\/tr> Disodium phosphate, 2 H 2<\/sub> O<\/td> 0.225 g<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
The solutions in chambers A (250 ml) and B (4 750 ml) are reconstituted with the reconstituted solution (5,000 ml), the composition of which is:
<\/p>\n\n\n\n <\/td> mmol \/ l<\/strong><\/td><\/tr><\/thead> Calcium Ca 2+<\/sup><\/td> 1.25<\/td><\/tr> Magnesium Mg 2+<\/sup><\/td> 0.6<\/td><\/tr> Sodium, Na\u00a0+<\/sup><\/td> 140<\/td><\/tr> Chloride, Cl –<\/sup><\/td> 115.9<\/td><\/tr> Hydrogen phosphate, HPO 4 <\/sub>2-<\/sup><\/td> 1.2<\/td><\/tr> Hydrogen carbonate, HCO 3 <\/sub>–<\/sup><\/td> 30<\/td><\/tr> Potassium, K\u00a0+<\/sup><\/td> 4<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Each carton contains two bags and a package leaflet.<\/p>\n\n\n\nMarketing Authorisation Holder<\/h2>\n\n\n\n