{"id":20809,"date":"2022-04-14T08:02:46","date_gmt":"2022-04-14T08:02:46","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20809"},"modified":"2022-04-15T15:25:38","modified_gmt":"2022-04-15T15:25:38","slug":"phosphoral","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/phosphoral\/","title":{"rendered":"Phosphoral | Sodium dihydrogen phosphate dihydrate \/ disodium phosphate dodecahydrate | uses, dose and side effects"},"content":{"rendered":"\n<p>24.4 g \/ 10.8 g&nbsp;oral&nbsp;solution<br>Sodium dihydrogen phosphate dihydrate\/disodium phosphate dodecahydrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Phosphoral is and what it is used for<\/h2>\n\n\n\n<p>Phosphorous is an intestinal cleanser that works by increasing the amount of water in the stool.&nbsp;It is a solution that you drink and that is provided in cartons containing two 45 ml bottles.&nbsp;One bottle contains a&nbsp;dose&nbsp;to be diluted with water before use (see section 3).<\/p>\n\n\n\n<p>You must take Phosphoral as a bowel cleanser before surgery and X-ray examination of the colon (&nbsp;colon&nbsp;) or examination of the bowel (&nbsp;endoscopy&nbsp;).&nbsp;The bowel must be empty so that doctors can see it.<\/p>\n\n\n\n<p>Phosphorous is not a remedy for constipation.<\/p>\n\n\n\n<p>Phosphoric should be used by adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Phosphoral<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Phosphoral<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to disodium phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are under 18 years of age.<\/li><li>if you are nauseous, vomit, or have stomach pain.<\/li><li>if you have kidney disease.<\/li><li>if you suffer from&nbsp;symptomatic&nbsp;heart disease.<\/li><li>if you have an abnormal accumulation of fluid in the abdominal cavity (&nbsp;ascites&nbsp;).<\/li><li>if you have or suspect you have a blockage, broken wound, or paralysis of the intestines.<\/li><li>if you have a congenital or acquired enlargement of the colon (megacolon).<\/li><li>if you have active&nbsp;inflammatory&nbsp;bowel disease.<\/li><li>if you have hyperactive parathyroid glands (hyperparathyroidism).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Phosphoral.<\/p>\n\n\n\n<p>Do not take Phosphoral with other&nbsp;laxatives&nbsp;that contain sodium phosphate.<\/p>\n\n\n\n<p>Consult your doctor if you suspect that any of the above applies to you.&nbsp;Your doctor will then decide if Phosphoral is right for you.<\/p>\n\n\n\n<p><strong>Take special care with Phosphoral:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are elderly or generally debilitated (65 years or older).<\/li><li>if you have impaired heart or kidney function.<\/li><li>if you have disturbances in the salinity of the body (electrolytic imbalance) or if you are at risk of having such disturbances, for example when you are dehydrated (dehydrated).<\/li><li>if you have low&nbsp;blood pressure&nbsp;or reduced bowel movements in some or all of the intestines.<\/li><li>if you have had surgery to remove a large bowel opening (&nbsp;colostomy&nbsp;) or small bowel opening (&nbsp;ileostomy&nbsp;).<\/li><li>if you have had any other gastrointestinal surgery.<\/li><li>if you are on a low-salt diet (&nbsp;<strong>see also important information on some ingredients in Phosphoral at the end of section 2).<\/strong><\/li><\/ul>\n\n\n\n<p>Talk to your doctor if you think any of these claims apply to you today or have ever happened to you before.&nbsp;Phosphoric may change the heart rhythm slightly as a result of disturbances in the electrolyte balance and consequently, you may need closer supervision during treatment.<\/p>\n\n\n\n<p>After taking Phosphoral, you can expect frequent and fluid bowel movements.&nbsp;You should drink as much clear drink (see point 3) as possible so that you do not become dehydrated (dehydrated).<\/p>\n\n\n\n<p>Phosphoric usually works within 30 minutes to 6 hours.&nbsp;If no bowel movement has been induced within 6 hours of taking either the first or second&nbsp;dose of&nbsp;Phosphoral, contact your doctor immediately as you may become dehydrated (dehydrated).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Phosphoral<\/h2>\n\n\n\n<p>Before you take Phosphoral, tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, in particular:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines used to treat high&nbsp;blood pressure&nbsp;or chest pain (&nbsp;angina pectoris&nbsp;) (eg calcium channel blockers,&nbsp;ACE inhibitors&nbsp;(angiotensin converting&nbsp;enzyme&nbsp;inhibitors ), angiotensin receptor blockers (ARBs)).<\/li><li>diuretics (&nbsp;diuretics&nbsp;).<\/li><li>non-steroidal anti-inflammatory painkillers (&nbsp;NSAIDs&nbsp;) such as <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/treo-comp\/\">Aspirin<\/a>.<\/li><li>certain remedies for mental illness (which contain lithium).<\/li><li>other medicines that can cause&nbsp;dehydration&nbsp;(dehydration) or affect different levels of salt (&nbsp;potassium&nbsp;, sodium,&nbsp;phosphate&nbsp;or water) in your body (your electrolyte balance).<\/li><li>drugs that change the rhythm of the heart.<\/li><li>drugs with&nbsp;parathyroid hormone.<\/li><li>medicines that are taken regularly by mouth e.g.&nbsp;birth control pills, antiepileptic&nbsp;drugs,&nbsp;or&nbsp;diabetes,&nbsp;and&nbsp;antibiotics&nbsp;such as Phosphoral can delay or completely prevent the uptake of these oral medications, reducing or destroying their effect.<\/li><\/ul>\n\n\n\n<p>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Phosphoric with food and drink<\/h2>\n\n\n\n<p>See section 3 of this leaflet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding or think you may be pregnant or are planning to have a baby, ask your doctor for advice before using Phosphoral.&nbsp;You should not use this medicine during pregnancy unless your doctor considers it necessary.&nbsp;If you are breastfeeding, you should milk out and discard the breast milk from the first&nbsp;dose&nbsp;one to 24 hours after the second&nbsp;dose&nbsp;of the bowel cleansing solutions.&nbsp;You should not breastfeed your baby for 24 hours after taking the second&nbsp;dose&nbsp;of Phosphoral.<\/p>\n\n\n\n<p><strong>Weakened and elderly patients (65 years or older)<\/strong><\/p>\n\n\n\n<p>Carefully read the information given in the sections \u201cTake special care with Phosphoral\u201d and \u201cUsing other medicines\u201d (above) and the instructions in section 3 (below).&nbsp;You may need closer supervision.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Do not drive or use machines or tools if you feel tired or dizzy or if you think you may be dehydrated (dehydrated) after taking Phosphoral.&nbsp;Also stay close to a toilet after taking this medicine.<\/p>\n\n\n\n<p>You are always responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Phosphoric contains sodium<\/h2>\n\n\n\n<p>This medicine contains 5000 mg of&nbsp;sodium&nbsp;(the main ingredient in cooking\/table salt) in each 45 ml&nbsp;dose.&nbsp;This corresponds to 250% of the recommended maximum daily intake of&nbsp;sodium&nbsp;for an adult.&nbsp;It should be noted that this may harm patients who require a low-sodium (low-salt) diet.<\/p>\n\n\n\n<p><strong>Phosphoric&nbsp;contains&nbsp;ethanol<\/strong><\/p>\n\n\n\n<p>This medicine contains small amounts of&nbsp;ethanol&nbsp;(alcohol), less than 100 mg per&nbsp;dose&nbsp;.<\/p>\n\n\n\n<p><strong>Phosphoric<\/strong> contains sodium benzoate<\/p>\n\n\n\n<p>This medicine contains 15 mg of sodium benzoate (E 211) in each 45 ml&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Phosphoral<\/h2>\n\n\n\n<p>Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>From the time you start taking Phosphoral until the examination is done, you must drink only &#8220;clear drink&#8221;.&nbsp;Do not eat solid foods.<\/li><li>&#8220;Clear beverage&#8221; includes water, broth, or soup that has been sieved to remove solids, sifted fruit juice without pulp (but no red or red-blue juice), tea, or coffee (without milk or cream), and clear carbonated or non-carbonated beverage t eg soft drinks.<\/li><li>To prevent you from feeling unwell while taking this medicine, it is important that you drink as much clear drink as possible.<\/li><li>Phosphorous can cause bowel movements similar to diarrhea.&nbsp;It often starts working within 30 minutes and can continue to work for up to 6 hours.&nbsp;Stay close to a toilet until bowel movements have stopped.<\/li><\/ul>\n\n\n\n<p>If bowel movements have not been induced within 6 hours after taking either the first or second&nbsp;dose of&nbsp;Phosphoral, you should contact your doctor immediately as you may become dehydrated (dehydrated).<\/p>\n\n\n\n<p>Treatment with Phosphoral should be started THE DAY BEFORE the hospital visit.<\/p>\n\n\n\n<p><strong>How to take the first or second&nbsp;dose&nbsp;of one<\/strong><\/p>\n\n\n\n<p>Dilute the contents of&nbsp;<strong>a<\/strong>&nbsp;bottle (45 ml) of Phosphoral in half a glass (120 ml) of cold water and drink.&nbsp;Then drink at least one full glass (240 ml) of cold water.&nbsp;Drink as large amounts of clear drink as possible to replace the fluid lost during bowel movements.<\/p>\n\n\n\n<p><strong>When to take the first or second&nbsp;dose&nbsp;one<\/strong><\/p>\n\n\n\n<p>See one of the two boxes below, depending on what time you have for the hospital visit.<\/p>\n\n\n\n<p>You must follow the instructions completely in order for the examination or operation to be performed.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><strong>MORNING VISIT AT&nbsp;8.00 &#8211; 12.00<\/strong><\/th><th scope=\"col\"><strong>AFTERNOON VISIT AT&nbsp;12.00 &#8211; 17.00<\/strong><\/th><\/tr><\/thead><tbody><tr><td><strong>THE&nbsp;DAY BEFORE THE EXAMINATION \/ OPERATION7 am<\/strong>&nbsp;&#8211; Instead of breakfast &#8211; drink at least one large glass (240 ml) clear drink, preferably more if desired. Immediately afterward&nbsp;take the&nbsp;first&nbsp;dose&nbsp;(see above).<br>Kl.&nbsp;13&nbsp;&#8211; Instead of lunch &#8211; drink at least three large glasses (720 ml) of clear drink.&nbsp;In the afternoon you can continue to drink clear drink to quench your thirst.<br>Kl.&nbsp;19&nbsp;&#8211; Instead of supper &#8211; drink at least one large glass (240 ml) clear drink, preferably more if desired.<br>Immediately afterward&nbsp;take the&nbsp;second&nbsp;dose&nbsp;(see above).<br>You can continue to drink clear drinks until midnight to quench your thirst.&nbsp;If you drink a clear drink after midnight, this can cause further toilet visits and result in lost sleep.<\/td><td><strong>THE DAY BEFORE THE EXAMINATION \/ operational.&nbsp;13<\/strong>&nbsp;&#8211; A light lunch can be eaten, such as soup and a sandwich.<br>After that, you must not eat any more solid food before the hospital visit.&nbsp;In the afternoon you can drink clear drink to quench your thirst.<br><strong>19<\/strong>&nbsp;&#8211; Instead of supper &#8211; drink at least one large glass (240 ml) clear drink, preferably more if desired.<br>Immediately afterwards&nbsp;<strong>take the&nbsp;first&nbsp;dose<\/strong>&nbsp;(see above).<br>During the evening, drink at least three full glasses (720 ml) of water or clear drink before going to bed.<\/td><\/tr><tr><td>&nbsp;<\/td><td><strong>EXAMINATION \/ OPERATION DAYKl.&nbsp;7<\/strong>&nbsp;&#8211; Instead of breakfast &#8211; drink at least a large glass of clear drink, preferably more if desired.<br>Immediately afterwards&nbsp;<strong>take the&nbsp;second&nbsp;dose<\/strong>&nbsp;(see above).<br>You can continue to drink clear drinks until 8 o&#8217;clock to quench your thirst.&nbsp;If you drink a clear drink after 8 o&#8217;clock, this can cause further toilet visits and result in you having difficulty getting to the hospital.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Be sure to drink large amounts of fluid after the hospital visit to replace the fluid that was lost while you were taking Phosphoral.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Phosphoral than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has ingested the medicine, contact a doctor or hospital for an assessment of the risk and advice.&nbsp;An excessive amount of the drug can cause&nbsp;dehydration&nbsp;(dehydration), problems with the heart and circulation, difficulty breathing, anxiety, and colic pain.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Phosphoral<\/h2>\n\n\n\n<p>Consult your doctor.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>In very rare cases, Phosphoral may cause severe allergic reactions with or without rash.&nbsp;Contact your doctor or emergency department at the nearest hospital&nbsp;<strong>immediately<\/strong>&nbsp;if your hands, face, lips, throat, or tongue begin to swell or if you have difficulty breathing or swallowing.<\/p>\n\n\n\n<p>Other possible&nbsp;side effects&nbsp;are caused by Phosphoral:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<p>nausea, abdominal pain, feeling of fullness in the stomach, diarrhea, chills, weakness, and dizziness.<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<p>vomiting, chest pain, and headache.<\/p>\n\n\n\n<p><strong>Uncommon (may&nbsp;<\/strong><strong>affect<\/strong>&nbsp;up to 1 in 100 people):<\/p>\n\n\n\n<p>dehydration&nbsp;(dehydration).<\/p>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<p>deposition of&nbsp;calcium&nbsp;in the kidneys.<\/p>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<p>heart attack, palpitations, low&nbsp;blood pressure, change in the number of salts (&nbsp;electrolytes&nbsp;) in the blood (which can lead to muscle twitching and&nbsp;spasms&nbsp;), muscle cramps, tingling, unconsciousness, and&nbsp;kidney failure.<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users): Hyponatremia (low sodium concentration in the blood which can lead to neurological disorders, such as confusion,&nbsp;coma,&nbsp;or seizures.<\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Phosphoral<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C<\/p>\n\n\n\n<p>Use immediately after opening.&nbsp;Discard any remaining solution.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance (s) are sodium dihydrogen phosphate dihydrate 24.4 g and disodium phosphate dodecahydrate 10.8 g each 45 ml&nbsp;dose.<\/li><li>The other ingredients are sodium benzoate (&nbsp;preservative&nbsp;E 211), saccharin sodium,&nbsp;glycerol, purified water and flavoring (ginger and lemon aroma) consisting of ginger balm, alcohol, lemon oil, terpene-reduced citric oil, citric acid and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Phosphorous is a clear, colorless&nbsp;oral&nbsp;solution with the scent of ginger and lemon.&nbsp;Phosphorous is supplied in cartons containing 2 or 100 ml bottles with screw caps.<\/p>\n\n\n\n<p>One bottle contains one&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorization Holder: Case Recordati SL, Autov\u00eda de Logro\u00f1a, km.&nbsp;13,300, 50180 Utebo, Zaragoza, Spain<\/p>\n\n\n\n<p>Manufacturer: Casen Recordati SL, Autovia de Logr\u00f5no, km.&nbsp;13,300, 50180 Utebo, Zaragoza, Spain.<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Denmark: Phosphoral&nbsp;oral&nbsp;solution<\/p>\n\n\n\n<p>Finland: Phosphoral oraaliliuos<\/p>\n\n\n\n<p>France: Recholan, buvable solution<\/p>\n\n\n\n<p>Greece: Phospho soda<\/p>\n\n\n\n<p>Ireland: Phospho-soda&nbsp;oral&nbsp;solution<\/p>\n\n\n\n<p>Netherlands: Phosphoral, drink<\/p>\n\n\n\n<p>Portugal: Phospho-Soda Oral&nbsp;Solution<\/p>\n\n\n\n<p>Spain: Phosphosoda&nbsp;oral solution<\/p>\n\n\n\n<p>United Kingdom: Phospho-soda&nbsp;oral&nbsp;solution<\/p>\n\n\n\n<p>Sweden: Phosphoral&nbsp;oral&nbsp;solution<\/p>\n\n\n\n<p>Germany: Phospho-soda solution for ingestion<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Phosphoral is an intestinal cleanser that works by increasing the amount of water in the stool. It is a solution that you drink and that is provided in cartons containing two 45 ml bottles. One bottle contains a dose to be diluted with water before use (see section 3).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21288,21292,21295,21284,21287,21289,21294,21293,21285,21290,21286,21291],"class_list":["post-20809","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-phosphoral","tag-disodium-phosphate-dodecahydrate","tag-disodium-phosphate-dodecahydrate-side-effects","tag-phosphoral","tag-phosphoral-side-effects","tag-sodium-dihydrogen","tag-what-disodium-phosphate-dodecahydrate-is-used-for","tag-what-is-disodium-phosphate-dodecahydrate","tag-what-is-phosphoral","tag-what-is-sodium-dihydrogen","tag-what-phosphoral-is-used-for","tag-what-sodium-dihydrogen-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20809","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20809"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20809\/revisions"}],"predecessor-version":[{"id":20863,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20809\/revisions\/20863"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20809"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20809"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20809"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}